Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04577 | 33574818 | Front Immunol | Predicting Non-Alcoholic Fatty Liver Disease Progression and Immune Deregulations by Specific Gene Expression Patterns. | 2021 | Details |
| A04584 | 33572810 | Nutrients | Krill Oil Supplementation Reduces Exacerbated Hepatic Steatosis Induced by Thermoneutral Housing in Mice with Diet-Induced Obesity. | 2021 | Details |
| A04602 | 33567543 | Nutrients | Implication between Genetic Variants from APOA5 and ZPR1 and NAFLD Severity in Patients with Hypertriglyceridemia. | 2021 | Details |
| A04611 | 33564651 | Clin Nutr Res | Probiotic Yogurt Fortified with Vitamin D Can Improve Glycemic Status in Non-Alcoholic Fatty Liver Disease Patients: a Randomized Clinical Trial. | 2021 | Details |
| A04629 | 33557355 | Life (Basel) | Sarcopenic Obesity in Non-Alcoholic Fatty Liver Disease-The Union of Two Culprits. | 2021 | Details |
| A04642 | 33554072 | iScience | Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega oxidation. | 2021 | Details |
| A04645 | 33553660 | JGH Open | Eradication of hepatitis C virus with direct-acting antivirals improves glycemic control in diabetes: A multicenter study. | 2020 | Details |
| A04658 | 33549451 | Nutr Metab Cardiovasc Dis | Apolipoprotein A5 controls fructose-induced metabolic dysregulation in mice. | 2020 | Details |
| A04662 | 33548387 | J Hepatol | FOXA3 induction under endoplasmic reticulum stress contributes to non-alcoholic fatty liver disease. | 2021 | Details |
| A04670 | 33546130 | Nutrients | Dietary Polyphenols and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04674 | 33545428 | Cell Mol Gastroenterol Hepatol | SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04675 | 33545391 | Mol Metab | Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH. | 2021 | Details |
| A04684 | 33542919 | Biomed Res Int | Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice. | 2021 | Details |
| A04690 | 33541129 | Exp Biol Med (Maywood) | Effect of vitamin D3 supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice. | 2021 | Details |
| A04694 | 33537464 | Biochem Biophys Rep | A high methionine and low folate diet alters glucose homeostasis and gut microbiome. | 2021 | Details |
| A04706 | 33534958 | ESC Heart Fail | Non-alcoholic fatty liver disease and heart failure with preserved ejection fraction: from pathophysiology to practical issues. | 2021 | Details |
| A04709 | 33532874 | Eur J Nutr | The effects of Chlorella supplementation on glycemic control, lipid profile and anthropometric measures on patients with type 2 diabetes mellitus. | 2021 | Details |
| A04725 | 33526807 | Lab Invest | NLRP3 deficiency did not attenuate NASH development under high fat calorie diet plus high fructose and glucose in drinking water. | 2021 | Details |
| A04750 | 33515696 | Cell Signal | Coordinated regulation of miR-27 by insulin/CREB/Hippo contributes to insulin resistance. | 2021 | Details |
| A04761 | 33513642 | Horm Metab Res | Insulin Resistance and Non-Alcoholic Fatty Liver Disease in Premenopausal Women with Metabolic Syndrome. | 2021 | Details |
| A04764 | 33513383 | J Steroid Biochem Mol Biol | Long-term androgen excess induces insulin resistance and non-alcoholic fatty liver disease in PCOS-like rats. | 2021 | Details |
| A04783 | 33506572 | Liver Int | Fibroblast Growth Factor 19: Potential modulation of hepatic metabolism for the treatment of non-alcoholic fatty liver disease. | 2021 | Details |
| A04784 | 33505944 | Can J Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases: The Heart of the Matter. | 2021 | Details |
| A04786 | 33505894 | Pediatr Gastroenterol Hepatol Nutr | Changes in Liver Enzymes and Metabolic Profile in Adolescents with Fatty Liver following Exercise Interventions. | 2021 | Details |
| A04787 | 33505505 | Evid Based Complement Alternat Med | A Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology. | 2021 | Details |
| A04792 | 33505147 | World J Gastroenterol | Experimental models of metabolic and alcoholic fatty liver disease. | 2021 | Details |
| A04798 | 33503814 | Int J Mol Sci | Mediators of Metabolism: An Unconventional Role for NOD1 and NOD2. | 2021 | Details |
| A04804 | 33500241 | J Lipid Res | Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation. | 2020 | Details |
| A04806 | 33498684 | Plants (Basel) | Plants of the Spontaneous Flora with Beneficial Action in the Management of Diabetes, Hepatic Disorders, and Cardiovascular Disease. | 2021 | Details |
| A04808 | 33498493 | J Clin Med | The Role of Hepatic Fat Accumulation in Glucose and Insulin Homeostasis-Dysregulation by the Liver. | 2021 | Details |
| A04811 | 33498326 | Cells | Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04827 | 33492440 | Eur J Pediatr | The triglycerides and glucose index is strongly associated with hepatic steatosis in children with overweight or obesity. | 2021 | Details |
| A04832 | 33490935 | JHEP Rep | (13C)-Methacetin breath test provides evidence of subclinical liver dysfunction linked to fat storage but not lifestyle. | 2020 | Details |
| A04851 | 33484089 | Andrology | Fatty liver index is associated with the risk of testosterone deficiency in aging men without metabolic syndrome. | 2021 | Details |
| A04853 | 33482185 | Life Sci | Beinaglutide shows significantly beneficial effects in diabetes/obesity-induced nonalcoholic steatohepatitis in ob/ob mouse model. | 2021 | Details |
| A04856 | 33479799 | Eur J Pediatr | Pulmonary function test abnormalities in children and adolescents with non-alcoholic fatty liver disease. | 2021 | Details |
| A04857 | 33479589 | Diabetol Int | Improved insulin sensitivity with sodium-glucose cotransporter 2 inhibitor treatment in a patient with slowly progressive type 1 diabetes mellitus with metabolic syndrome: a case report. | 2020 | Details |
| A04863 | 33477579 | J Clin Med | Association of NAFLD and Insulin Resistance with Non Metastatic Bladder Cancer Patients: A Cross-Sectional Retrospective Study. | 2021 | Details |
| A04868 | 33475559 | J Pak Med Assoc | Non-alcoholic fatty liver disease: A real threat in Pakistan. | 2020 | Details |
| A04870 | 33474802 | Pharmacol Res Perspect | Dexmedetomidine ameliorates high-fat diet-induced nonalcoholic fatty liver disease by targeting SCD1 in obesity mice. | 2021 | Details |
| A04874 | 33471632 | Am J Physiol Gastrointest Liver Physiol | Bacterial and eukaryotic extracellular vesicles and nonalcoholic fatty liver disease: new players in the gut-liver axis? | 2021 | Details |
| A04876 | 33470903 | Am J Physiol Gastrointest Liver Physiol | GCSF deficiency attenuates nonalcoholic fatty liver disease through regulating GCSFR-SOCS3-JAK-STAT3 pathway and immune cells infiltration. | 2021 | Details |
| A04882 | 33468321 | Trends Pharmacol Sci | Triglycerides in Nonalcoholic Fatty Liver Disease: Guilty Until Proven Innocent. | 2021 | Details |
| A04894 | 33464677 | Diabetes Obes Metab | Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review. | 2021 | Details |
| A04907 | 33455863 | Trends Endocrinol Metab | Role of Macrophages in the Endocrine System. | 2021 | Details |
| A04918 | 33449917 | Endocr Connect | Pathophysiology of NASH in endocrine diseases. | 2021 | Details |
| A04932 | 33445096 | J Affect Disord | Effects of Alpha-2-HS-glycoprotein on cognitive and emotional assessment in prediabetic and diabetic subjects. | 2020 | Details |
| A04966 | 33436321 | Dig Liver Dis | Clinical characteristics of metabolic associated fatty liver disease (MAFLD) in subjects with myotonic dystrophy type 1 (DM1). | 2021 | Details |
| A04986 | 33424768 | Front Endocrinol (Lausanne) | Harnessing Muscle-Liver Crosstalk to Treat Nonalcoholic Steatohepatitis. | 2020 | Details |
| A04989 | 33422644 | Mol Metab | Neonatal overfeeding during lactation rapidly and permanently misaligns the hepatic circadian rhythm and programmes adult NAFLD. | 2021 | Details |
| A04992 | 33421970 | Turk J Med Sci | The effect of 1,25-dihydroxyvitamin D3 on liver damage, oxidative stress, and advanced glycation end products in experimental nonalcoholic- and alcoholic- fatty liver disease | 2021 | Details |
| A04997 | 33421258 | J Biochem Mol Toxicol | The protective effects of trelagliptin on high-fat diet-induced nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A05002 | 33417961 | Life Sci | Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity. | 2021 | Details |
| A05004 | 33417276 | Mol Syst Biol | Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis. | 2021 | Details |
| A05008 | 33413060 | Curr Med Chem | Lipid Metabolism and Relevant Disorders to Female Reproductive Health. | 2021 | Details |
| A05009 | 33411984 | J Appl Microbiol | The interplay between host cellular and gut microbial metabolism in NAFLD development and prevention. | 2021 | Details |
| A05016 | 33409407 | Transl Gastroenterol Hepatol | Metabolic syndrome following liver transplantation in nonalcoholic steatohepatitis. | 2021 | Details |
| A05019 | 33409397 | Transl Gastroenterol Hepatol | Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). | 2021 | Details |
| A05020 | 33408593 | EXCLI J | Plasma vascular endothelial growth factor B is elevated in non-alcoholic fatty liver disease patients and associated with blood pressure and renal dysfunction. | 2020 | Details |
| A05025 | 33406763 | Int J Mol Sci | Immunity as Cornerstone of Non-Alcoholic Fatty Liver Disease: The Contribution of Oxidative Stress in the Disease Progression. | 2021 | Details |
| A05030 | 33401717 | Int J Mol Sci | Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. | 2021 | Details |
| A05043 | 33396939 | Int J Mol Sci | Deletion of KLF10 Leads to Stress-Induced Liver Fibrosis upon High Sucrose Feeding. | 2020 | Details |
| A05050 | 33394549 | Diabetes Obes Metab | Nonalcoholic fatty liver disease, diastolic dysfunction, and impaired myocardial glucose uptake in patients with type 2 diabetes. | 2021 | Details |
| A05063 | 33390768 | Int J Med Sci | Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function. | 2021 | Details |
| A05068 | 33388736 | Orv Hetil | Sarcopenia - 2021: Pathophysiology, diagnosis, therapy | 2021 | Details |
| A05087 | 33382757 | PLoS One | Nut consumption and the prevalence and severity of non-alcoholic fatty liver disease. | 2020 | Details |
| A05091 | 33381084 | Front Endocrinol (Lausanne) | FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases. | 2020 | Details |
| A05098 | 33377125 | Cell Rep Med | Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes. | 2020 | Details |
| A05112 | 33371482 | Biomolecules | Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants. | 2020 | Details |
| A05116 | 33370454 | J Gastroenterol Hepatol | Association between the severity of liver fibrosis and cardiovascular outcomes in patients with type 2 diabetes. | 2021 | Details |
| A05118 | 33369197 | Mol Nutr Food Res | Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice. | 2021 | Details |
| A05119 | 33368954 | Diabetes Obes Metab | Pioglitazone and bariatric surgery are the most effective treatments for non-alcoholic steatohepatitis: A hierarchical network meta-analysis. | 2021 | Details |
| A05122 | 33365151 | J Ultrason | Shear wave elastography reveals a high prevalence of liver fibrosis in overweight or obese Hispanic youth. | 2020 | Details |
| A05123 | 33364879 | Sisli Etfal Hastan Tip Bul | The Relationship between Insulin Resistance and Liver Damage in non-alcoholic Fatty Liver Patients. | 2020 | Details |
| A05127 | 33363067 | Front Pediatr | New Perspectives on Genetic Prediction for Pediatric Metabolic Associated Fatty Liver Disease. | 2020 | Details |
| A05137 | 33359401 | Mol Metab | Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease. | 2020 | Details |
| A05138 | 33359400 | Mol Metab | Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH. | 2020 | Details |
| A05148 | 33354866 | Liver Int | Glycogenosis is common in nonalcoholic fatty liver disease and is independently associated with ballooning, but lower steatosis and lower fibrosis. | 2021 | Details |
| A05156 | 33352183 | Eur J Pharmacol | The effects of glucagon-like peptide-1 receptor agonists on glycemic control and anthropometric profiles among diabetic patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. | 2020 | Details |
| A05185 | 33343508 | Front Endocrinol (Lausanne) | ChREBP-Mediated Regulation of Lipid Metabolism: Involvement of the Gut Microbiota, Liver, and Adipose Tissue. | 2020 | Details |
| A05191 | 33341312 | Clin Nutr | A randomized controlled clinical trial comparing calcitriol versus cholecalciferol supplementation to reduce insulin resistance in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A05207 | 33339155 | Antioxidants (Basel) | N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature. | 2020 | Details |
| A05208 | 33338730 | Ultrasonics | Utility of quantitative ultrasound in community screening for hepatic steatosis. | 2020 | Details |
| A05215 | 33336025 | Open Med (Wars) | Effect of glucagon-like peptide-1 receptor agonists on adipokine level of nonalcoholic fatty liver disease in rats fed high-fat diet. | 2020 | Details |
| A05218 | 33334622 | Arch Med Res | Epidemiology, Pathogenesis, Diagnosis and Emerging Treatment of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05225 | 33333040 | Clin Chim Acta | Development and validation of a noninvasive clinical scoring system to predict significant fibrosis in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A05234 | 33328987 | Front Pharmacol | Da-Chai-Hu Decoction Ameliorates High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Through Remodeling the Gut Microbiota and Modulating the Serum Metabolism. | 2020 | Details |
| A05237 | 33328206 | Diabetes | Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver. | 2020 | Details |
| A05240 | 33327438 | Int J Mol Sci | Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05244 | 33326684 | IUBMB Life | Combination of metformin and chlorogenic acid attenuates hepatic steatosis and inflammation in high-fat diet fed mice. | 2020 | Details |
| A05249 | 33324348 | Front Endocrinol (Lausanne) | Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides. | 2020 | Details |
| A05251 | 33323806 | Chin Med J (Engl) | MAFLD vs. NAFLD: shared features and potential changes in epidemiology, pathophysiology, diagnosis, and pharmacotherapy. | 2020 | Details |
| A05255 | 33321448 | Complement Ther Clin Pract | Efficacy of resveratrol supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trials. | 2020 | Details |
| A05266 | 33319459 | Liver Int | Metabolic-associated fatty liver disease (MAFLD) in coeliac disease. | 2020 | Details |
| A05281 | 33313159 | Ann Transl Med | Development of a simple nonalcoholic fatty liver disease scoring system indicative of metabolic risks and insulin resistance. | 2020 | Details |
| A05287 | 33312420 | World J Hepatol | Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo. | 2020 | Details |
| A05288 | 33311949 | World J Gastroenterol | Prevalence and predictors of nonalcoholic fatty liver disease in South Asian women with polycystic ovary syndrome. | 2020 | Details |
| A05294 | 33310034 | Life Sci | Aerobic training improves NAFLD markers and insulin resistance through AMPK-PPAR-α signaling in obese mice. | 2020 | Details |
| A05297 | 33309563 | Clin Res Hepatol Gastroenterol | Liraglutide in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials. | 2020 | Details |
| A05303 | 33308192 | BMC Complement Med Ther | Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-δ. | 2020 | Details |