Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A05571 | 33203257 | Int J Food Sci Nutr | Hepatoprotective and anti-inflammatory effects of a standardized pomegranate (Punica granatum) fruit extract in high fat diet-induced obese C57BL/6 mice. | 2020 | Details |
| A05577 | 33202166 | J Med Food | Water Extract of Artemisia annua L. Exhibits Hepatoprotective Effects Through Improvement of Lipid Accumulation and Oxidative Stress-Induced Cytotoxicity. | 2020 | Details |
| A05584 | 33199780 | Nat Commun | AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis. | 2020 | Details |
| A05590 | 33197790 | Environ Int | Unravelling the metabolic alterations of liver damage induced by thirdhand smoke. | 2020 | Details |
| A05600 | 33194172 | Ther Adv Endocrinol Metab | The relation between serum adipose differentiation-related protein and non-alcoholic fatty liver disease in type 2 diabetes mellitus. | 2020 | Details |
| A05606 | 33191205 | Exp Cell Res | CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway. | 2020 | Details |
| A05608 | 33190588 | Autophagy | TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation. | 2020 | Details |
| A05613 | 33187321 | Pharmaceuticals (Basel) | Germinated Soybean Embryo Extract Ameliorates Fatty Liver Injury in High-Fat Diet-Fed Obese Mice. | 2020 | Details |
| A05614 | 33187278 | Nutrients | The Relationship between Prebiotic Supplementation and Anthropometric and Biochemical Parameters in Patients with NAFLD-A Systematic Review and Meta-Analysis of Randomized Controlled Trials. | 2020 | Details |
| A05618 | 33186758 | Mol Metab | Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD. | 2020 | Details |
| A05630 | 33182700 | Nutrients | Fructose-Induced Intestinal Microbiota Shift Following Two Types of Short-Term High-Fructose Dietary Phases. | 2020 | Details |
| A05631 | 33182043 | Int Immunopharmacol | Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice. | 2020 | Details |
| A05655 | 33171699 | Diagnostics (Basel) | Predictive Value of Serum Ferritin in Combination with Alanine Aminotransferase and Glucose Levels for Noninvasive Assessment of NAFLD: Fatty Liver in Obesity (FLiO) Study. | 2020 | Details |
| A05658 | 33170809 | JCI Insight | Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in humans. | 2020 | Details |
| A05673 | 33164439 | Zhongguo Zhong Yao Za Zhi | [Effect of Panax japonicus saponin Ⅳa on alleviating nonalcoholic steatohepatitis by regulating miR-17-5p/MFN2 signaling pathway]. | 2020 | Details |
| A05685 | 33159388 | FEBS Open Bio | MiR-22 modulates the expression of lipogenesis-related genes and promotes hepatic steatosis in vitro. | 2020 | Details |
| A05689 | 33157223 | J Ethnopharmacol | Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells. | 2020 | Details |
| A05695 | 33152943 | Biomed Pharmacother | The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling. | 2020 | Details |
| A05696 | 33152542 | Clin Gastroenterol Hepatol | A Phase 2 Double Blinded, Randomized Controlled Trial of Saroglitazar in Patients With Nonalcoholic Steatohepatitis. | 2020 | Details |
| A05697 | 33152322 | Cell Metab | TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation. | 2020 | Details |
| A05709 | 33146212 | Food Funct | The influence of dietary conditions in the effects of resveratrol on hepatic steatosis. | 2020 | Details |
| A05713 | 33144913 | Oxid Med Cell Longev | Amelioration by Idesia polycarpa Maxim. var. vestita Diels. of Oleic Acid-Induced Nonalcoholic Fatty Liver in HepG2 Cells through Antioxidant and Modulation of Lipid Metabolism. | 2020 | Details |
| A05720 | 33143628 | Curr Diabetes Rev | Hepatic Mediators of Lipid Metabolism and Ketogenesis: Focus on Fatty Liver and Diabetes. | 2021 | Details |
| A05738 | 33137488 | Mol Metab | The absence of hepatic glucose-6 phosphatase/ChREBP couple is incompatible with survival in mice. | 2020 | Details |
| A05742 | 33135718 | Food Funct | Integrative transcriptomics and metabolomics explore the mechanism of kaempferol on improving nonalcoholic steatohepatitis. | 2020 | Details |
| A05752 | 33132636 | World J Gastroenterol | Is vitamin D receptor a druggable target for non-alcoholic steatohepatitis? | 2020 | Details |
| A05756 | 33131747 | Life Sci | Metabolomic-proteomic combination analysis reveals the targets and molecular pathways associated with hydrogen sulfide alleviating NAFLD. | 2020 | Details |
| A05775 | 33125080 | J Clin Endocrinol Metab | Relationship of IGF-1 and IGF-Binding Proteins to Disease Severity and Glycemia in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A05779 | 33122078 | Gene | TCTP participates in hepatic metabolism by regulating gene expression involved in insulin resistance. | 2020 | Details |
| A05780 | 33121337 | Cell Cycle | Gypenosides improves nonalcoholic fatty liver disease induced by high-fat diet induced through regulating LPS/TLR4 signaling pathway. | 2020 | Details |
| A05787 | 33117273 | Front Endocrinol (Lausanne) | Palmitoleic Acid Decreases Non-alcoholic Hepatic Steatosis and Increases Lipogenesis and Fatty Acid Oxidation in Adipose Tissue From Obese Mice. | 2020 | Details |
| A05794 | 33114589 | Molecules | Modulation of Lipid Metabolism by Trans-Anethole in Hepatocytes. | 2020 | Details |
| A05799 | 33114290 | Int J Mol Sci | The Molecular Mechanisms of Iron Metabolism and Its Role in Cardiac Dysfunction and Cardioprotection. | 2020 | Details |
| A05800 | 33114278 | Antioxidants (Basel) | Consumption of Spinach and Tomato Modifies Lipid Metabolism, Reducing Hepatic Steatosis in Rats. | 2020 | Details |
| A05804 | 33113993 | Nutrients | Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation. | 2020 | Details |
| A05808 | 33112796 | J Endocrinol | GH directly inhibits steatosis and liver injury in a sex-dependent and IGF1-independent manner. | 2021 | Details |
| A05813 | 33110145 | Sci Rep | NMR microsystem for label-free characterization of 3D nanoliter microtissues. | 2020 | Details |
| A05816 | 33108854 | Diabetes Metab J | Magnetic Resonance-Based Assessments Better Capture Pathophysiologic Profiles and Progression in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05829 | 33105554 | Nutrients | Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats. | 2020 | Details |
| A05833 | 33103450 | Am J Physiol Endocrinol Metab | Holistic characterization of single-hepatocyte transcriptome responses to high-fat diet. | 2020 | Details |
| A05851 | 33101626 | Frontline Gastroenterol | Non-alcoholic fatty liver disease (NAFLD) in non-obese individuals. | 2019 | Details |
| A05853 | 33101207 | Front Endocrinol (Lausanne) | Chinese Medicinal Herbs Targeting the Gut-Liver Axis and Adipose Tissue-Liver Axis for Non-Alcoholic Fatty Liver Disease Treatments: The Ancient Wisdom and Modern Science. | 2020 | Details |
| A05854 | 33101202 | Front Endocrinol (Lausanne) | Dynamic Changes in Circulating Endocrine FGF19 Subfamily and Fetuin-A in Response to Intralipid and Insulin Infusions in Healthy and PCOS Women. | 2020 | Details |
| A05857 | 33098868 | Arch Biochem Biophys | miR-34a regulates lipid metabolism by targeting SIRT1 in non-alcoholic fatty liver disease with iron overload. | 2020 | Details |
| A05873 | 33093014 | Diabetes | ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway. | 2020 | Details |
| A05882 | 33090099 | Turk J Gastroenterol | Morphological evaluation of the effects of exercise on high-fat-diet-induced liver damage in rats. | 2020 | Details |
| A05909 | 33078906 | FASEB J | Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism. | 2020 | Details |
| A05916 | 33076582 | Life (Basel) | Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized Mice. | 2020 | Details |
| A05918 | 33076344 | Biology (Basel) | The Nuclear Envelope in Lipid Metabolism and Pathogenesis of NAFLD. | 2020 | Details |
| A05921 | 33075563 | Cell Mol Gastroenterol Hepatol | S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis. | 2020 | Details |
| A05936 | 33071788 | Front Pharmacol | Veratrilla baillonii Franch Could Alleviate Lipid Accumulation in LO2 Cells by Regulating Oxidative, Inflammatory, and Lipid Metabolic Signaling Pathways. | 2020 | Details |
| A05946 | 33067533 | Sci Rep | HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. | 2020 | Details |
| A05947 | 33066497 | J Pers Med | Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development. | 2020 | Details |
| A05953 | 33064150 | J Clin Endocrinol Metab | The PNPLA3-I148M Variant Confers an Antiatherogenic Lipid Profile in Insulin-resistant Patients. | 2021 | Details |
| A05955 | 33062150 | Oxid Med Cell Longev | Prevention of Nonalcoholic Hepatic Steatosis by Shenling Baizhu Powder: Involvement of Adiponectin-Induced Inhibition of Hepatic SREBP-1c. | 2020 | Details |
| A05958 | 33061754 | Turk Pediatri Ars | The association of lipid metabolism and non-alcoholic fatty liver disease in children with obesity. | 2020 | Details |
| A05960 | 33061293 | Drug Des Devel Ther | Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice. | 2020 | Details |
| A05963 | 33060460 | Curr Opin Clin Nutr Metab Care | Protein and amino acids in nonalcoholic fatty liver disease. | 2021 | Details |
| A05973 | 33055335 | Wiad Lek | APOPTOTIC PROCESSES' RESEARCH ON THE MODEL OF TYPE 2 DIABETES MELLITUS ON OBESITY'S BACKGROUND UNDER THE INFLUENCE OF DENSE BEAN EXTRACT. | 2020 | Details |
| A05988 | 33050067 | Biomolecules | Pharmaceutical Efficacy of Gypenoside LXXV on Non-Alcoholic Steatohepatitis (NASH). | 2020 | Details |
| A05989 | 33050035 | Cells | Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation. | 2020 | Details |
| A06004 | 33040080 | Cell Death Dis | USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638. | 2020 | Details |
| A06009 | 33038502 | Contemp Clin Trials | A randomised, double-blind, placebo-controlled, multi-centre, dose-range, proof-of-concept, 24-week treatment study of lanifibranor in adult subjects with non-alcoholic steatohepatitis: Design of the NATIVE study. | 2020 | Details |
| A06013 | 33037981 | Hepatol Int | Exosomal miR-199a-5p promotes hepatic lipid accumulation by modulating MST1 expression and fatty acid metabolism. | 2020 | Details |
| A06017 | 33037751 | Phytother Res | Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling. | 2020 | Details |
| A06019 | 33037652 | J Food Sci | Coniferaldehyde ameliorates the lipid and glucose metabolism in palmitic acid-induced HepG2 cells via the LKB1/AMPK signaling pathway. | 2020 | Details |
| A06020 | 33037249 | Sci Rep | Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis. | 2020 | Details |
| A06022 | 33036939 | Surg Obes Relat Dis | Recent advances in the mechanisms underlying the beneficial effects of bariatric and metabolic surgery. | 2020 | Details |
| A06025 | 33036257 | Cells | Playing Jekyll and Hyde-The Dual Role of Lipids in Fatty Liver Disease. | 2020 | Details |
| A06050 | 33027743 | Biomed Pharmacother | Sagittaria sagittifolia polysaccharide interferes with arachidonic acid metabolism in non-alcoholic fatty liver disease mice via Nrf2/HO-1 signaling pathway. | 2020 | Details |
| A06051 | 33027714 | Pharmacol Res | FATP2-targeted therapies - A role beyond fatty liver disease. | 2020 | Details |
| A06052 | 33027657 | Cell Rep | Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content. | 2020 | Details |
| A06053 | 33027655 | Cell Rep | The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development. | 2020 | Details |
| A06056 | 33026380 | Food Funct | Gut inflammation exacerbates hepatic injury in C57BL/6J mice via gut-vascular barrier dysfunction with high-fat-incorporated meat protein diets. | 2020 | Details |
| A06061 | 33024914 | Hepatol Commun | LPCN 1144 Resolves NAFLD in Hypogonadal Males. | 2020 | Details |
| A06071 | 33017610 | J Nutr Biochem | Liver lipidome signature and metabolic pathways in nonalcoholic fatty liver disease induced by a high-sugar diet. | 2020 | Details |
| A06078 | 33014333 | Cell Biosci | Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice. | 2020 | Details |
| A06088 | 33011191 | Prog Lipid Res | The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation. | 2020 | Details |
| A06089 | 33010471 | Mol Metab | Dysregulated lipid metabolism links NAFLD to cardiovascular disease. | 2020 | Details |
| A06105 | 33006712 | Mol Biol Rep | Low-dose trans-resveratrol induce poly(ADP)-ribosylation-dependent increase of the PPAR-γ protein expression level in the in vitro model of non-alcoholic fatty liver disease. | 2020 | Details |
| A06109 | 33004402 | BMJ Open Diabetes Res Care | Metabolic and energetic benefits of microRNA-22 inhibition. | 2020 | Details |
| A06124 | 32997875 | Mol Nutr Food Res | Characterization of the Nutritional Composition of a Biotechnologically Produced Oyster Mushroom and its Physiological Effects in Obese Zucker Rats. | 2020 | Details |
| A06125 | 32997872 | Mol Nutr Food Res | CREBH: A Complex Array of Regulatory Mechanisms in Nutritional Signaling, Metabolic Inflammation, and Metabolic Disease. | 2020 | Details |
| A06127 | 32996649 | FASEB J | N-glycosylation of CREBH improves lipid metabolism and attenuates lipotoxicity in NAFLD by modulating PPARα and SCD-1. | 2020 | Details |
| A06135 | 32993055 | Int J Mol Sci | Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress. | 2020 | Details |
| A06136 | 32992548 | Antioxidants (Basel) | Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro. | 2020 | Details |
| A06137 | 32992234 | Adv Biol Regul | The roles of osteocalcin in lipid metabolism in adipose tissue and liver. | 2020 | Details |
| A06161 | 32982113 | World J Gastroenterol | Acupuncture improved lipid metabolism by regulating intestinal absorption in mice. | 2020 | Details |
| A06162 | 32982112 | World J Gastroenterol | Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation. | 2020 | Details |
| A06171 | 32979393 | Toxicol Appl Pharmacol | Perfluorooctanesulfonic acid (PFOS) administration shifts the hepatic proteome and augments dietary outcomes related to hepatic steatosis in mice. | 2020 | Details |
| A06183 | 32977490 | Cells | The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging. | 2020 | Details |
| A06187 | 32976958 | Toxicology | Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease. | 2020 | Details |
| A06212 | 32965675 | Hepatology | Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A06218 | 32964054 | J Diabetes Res | Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients. | 2020 | Details |
| A06232 | 32961235 | Life Sci | Liraglutide modulates gut microbiome and attenuates nonalcoholic fatty liver in db/db mice. | 2020 | Details |
| A06243 | 32953932 | Mol Ther Methods Clin Dev | Soluble Klotho Improves Hepatic Glucose and Lipid Homeostasis in Type 2 Diabetes. | 2020 | Details |
| A06258 | 32951410 | Clin Mol Hepatol | Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases. | 2020 | Details |
| A06259 | 32951289 | Physiol Rep | Targeted and untargeted metabolomics provide insight into the consequences of glycine-N-methyltransferase deficiency including the novel finding of defective immune function. | 2020 | Details |
| A06262 | 32947972 | Int J Mol Sci | NASH, Fibrosis and Hepatocellular Carcinoma: Lipid Synthesis and Glutamine/Acetate Signaling. | 2020 | Details |
| A06263 | 32947952 | Nutrients | Anti-Diabetic Obesity Effects of Wasabia Japonica Matsum Leaf Extract on 45% Kcal High-Fat Diet-Fed Mice. | 2020 | Details |