Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A33386 | 26085918 | World J Hepatol | Burden of nonalcoholic fatty liver disease and advanced fibrosis in a Texas Hispanic community cohort. | 2015 | Details |
| A33388 | 26082668 | Hepat Med | Tyrosine levels are associated with insulin resistance in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A33409 | 26052340 | Nutr Metab (Lond) | E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish. | 2015 | Details |
| A33424 | 26023714 | Int J Mol Sci | 1,8-Cineole Ameliorates Steatosis of Pten Liver Specific KO Mice via Akt Inactivation. | 2015 | Details |
| A33442 | 25978364 | PLoS One | Liver injury and fibrosis induced by dietary challenge in the Ossabaw miniature Swine. | 2015 | Details |
| A33468 | 25926979 | F1000Prime Rep | Recent advances in understanding/management of non-alcoholic steatohepatitis. | 2015 | Details |
| A33489 | 25888871 | Lipids Health Dis | High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice. | 2015 | Details |
| A33490 | 25888330 | Gastroenterology | Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. | 2015 | Details |
| A33492 | 25885479 | J Agric Food Chem | Dietary Supplementation of Genistein Alleviates Liver Inflammation and Fibrosis Mediated by a Methionine-Choline-Deficient Diet in db/db Mice. | 2015 | Details |
| A33505 | 25848483 | World J Hepatol | Prevention of hepatocellular carcinoma: Focusing on antioxidant therapy. | 2015 | Details |
| A33515 | 25830098 | Mol Metab | The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis. | 2015 | Details |
| A33547 | 25747274 | Gastroenterology | β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis. | 2015 | Details |
| A33550 | 25741394 | Open Respir Med J | Physical activity in adults with cystic fibrosis receiving intravenous antibiotics in hospital and in the community. | 2015 | Details |
| A33561 | 25713889 | Hepatogastroenterology | Patient age and extent of liver resection influence outcome of liver resection for hepatocellular carcinoma in non-cirrhotic liver. | 2014 | Details |
| A33638 | 25537773 | Curr Gene Ther | miR-122 is a unique molecule with great potential in diagnosis, prognosis of liver disease, and therapy both as miRNA mimic and antimir. | 2015 | Details |
| A33639 | 25536170 | J Agric Food Chem | Purified anthocyanins from bilberry and black currant attenuate hepatic mitochondrial dysfunction and steatohepatitis in mice with methionine and choline deficiency. | 2015 | Details |
| A33643 | 25532502 | Dig Dis Sci | Curcumin targets multiple pathways to halt hepatic stellate cell activation: updated mechanisms in vitro and in vivo. | 2014 | Details |
| A33651 | 25496225 | Aliment Pharmacol Ther | A retrospective 15-year review: survival advantage after switching to sirolimus in hepatitis C virus infected liver graft recipients. | 2014 | Details |
| A33676 | 25448926 | Gastroenterology | Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice. | 2014 | Details |
| A33735 | 25279794 | Endocrinology | Osteocalcin protects against nonalcoholic steatohepatitis in a mouse model of metabolic syndrome. | 2014 | Details |
| A33818 | 25082518 | Cancer Chemother Pharmacol | Chemotherapy-associated steatohepatitis induced by irinotecan: a novel animal model. | 2014 | Details |
| A33828 | 25066692 | Gastroenterology | Roles for chemokines in liver disease. | 2014 | Details |
| A33835 | 25046161 | Gastroenterology | Cell death and cell death responses in liver disease: mechanisms and clinical relevance. | 2014 | Details |
| A33867 | 24988445 | PLoS One | Histopathologic alterations associated with global gene expression due to chronic dietary TCDD exposure in juvenile zebrafish. | 2014 | Details |
| A33899 | 24930642 | Intern Med | Investigation of ornithine carbamoyltransferase as a biomarker of liver cirrhosis. | 2014 | Details |
| A33927 | 24842243 | Diabetes Res Clin Pract | Sitagliptin attenuates methionine/choline-deficient diet-induced steatohepatitis. | 2014 | Details |
| A33935 | 24827559 | Hepatol Res | High-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats. | 2014 | Details |
| A33966 | 24763197 | Exp Mol Med | Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice. | 2014 | Details |
| A33969 | 24759660 | PLoS One | Functions of liver natural killer cells are dependent on the severity of liver inflammation and fibrosis in chronic hepatitis C. | 2014 | Details |
| A33998 | 24669237 | Exp Ther Med | Effects of pioglitazone on nonalcoholic steatohepatitis in a patient with anorexia nervosa: A case report. | 2014 | Details |
| A34016 | 24619556 | Hepatology | E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network. | 2014 | Details |
| A34018 | 24614199 | Lab Invest | Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. | 2014 | Details |
| A34035 | 24582082 | Dig Liver Dis | Lack of interleukin-1α in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice. | 2014 | Details |
| A34044 | 24570954 | Hepatobiliary Surg Nutr | Eat more carrots? Dampening cell death in ethanol-induced liver fibrosis by β-carotene. | 2013 | Details |
| A34087 | 24445574 | Am J Gastroenterol | The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis. | 2014 | Details |
| A34110 | 26709386 | Mol Cell Oncol | TAK1-dependent autophagy: A suppressor of fatty liver disease and hepatic oncogenesis. | 2014 | Details |
| A34125 | 26858882 | Cell Med | Electron Therapy Attenuated Elevated Alanine Aminotransferase and Oxidative Stress Values in Type 2 Diabetes-Induced Nonalcoholic Steatohepatitis of Rats. | 2013 | Details |
| A34126 | 26858881 | Cell Med | Experimental Nonalcoholic Steatohepatitis Induced by Neonatal Streptozotocin Injection and a High-Fat Diet in Rats. | 2013 | Details |
| A34154 | 24303091 | World J Hepatol | Increased bone mineral density in patients with non-alcoholic steatohepatitis. | 2013 | Details |
| A34156 | 26202298 | Hepatol Int | Pharmacological agents for nonalcoholic steatohepatitis. | 2013 | Details |
| A34187 | 24189085 | BMJ Open | Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial. | 2013 | Details |
| A34199 | 24145238 | Lab Invest | A novel mouse model of nonalcoholic steatohepatitis with significant insulin resistance. | 2013 | Details |
| A34229 | 24021426 | J Hepatol | Serum FGF21 increases with hepatic fat accumulation in pediatric onset intestinal failure. | 2013 | Details |
| A34237 | 23996730 | Hepatology | Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. | 2013 | Details |
| A34254 | 23948302 | J Autoimmun | STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib. | 2013 | Details |
| A34278 | 23877747 | Nutr Diabetes | Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury. | 2013 | Details |
| A34280 | 23872024 | Free Radic Biol Med | Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis. | 2013 | Details |
| A34295 | 23832448 | Hepatology | Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A34303 | 26201922 | Hepatol Int | Three-dimensional magnetic resonance imaging for stringent diagnosis of advanced fibrosis associated with nonalcoholic steatohepatitis. | 2013 | Details |
| A34310 | 23793039 | Food Chem Toxicol | Nuclear erythroid 2-related factor 2: a novel potential therapeutic target for liver fibrosis. | 2013 | Details |
| A34313 | 23777387 | Hepatol Res | Therapeutic effects of the direct renin inhibitor, aliskiren, on non-alcoholic steatohepatitis in fatty liver Shionogi ob/ob male mice. | 2013 | Details |
| A34333 | 26838973 | Surg Pathol Clin | Nonalcoholic Steatohepatitis: Diagnostic Challenges. | 2013 | Details |
| A34335 | 26201785 | Hepatol Int | B cell-activating factor is associated with the histological severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A34361 | 23640861 | Toxicol Sci | Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice. | 2013 | Details |
| A34404 | 23536281 | Virchows Arch | In the non-cirrhotic stage of nonalcoholic steatohepatitis, angioarchitecture of portal veins and lobular architecture are maintained. | 2013 | Details |
| A34410 | 23526264 | J Clin Biochem Nutr | Effects of tocotrienol on tumor necrosis factor-α/d-galactosamine-induced steatohepatitis in rats. | 2013 | Details |
| A34412 | 23520531 | PLoS One | Effect of meal ingestion on liver stiffness in patients with cirrhosis and portal hypertension. | 2013 | Details |
| A34425 | 23481610 | Toxicol Appl Pharmacol | Persistent fibrosis in the liver of choline-deficient and iron-supplemented L-amino acid-defined diet-induced nonalcoholic steatohepatitis rat due to continuing oxidative stress after choline supplementation. | 2013 | Details |
| A34441 | 23448275 | Hepatol Res | Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model. | 2013 | Details |
| A34453 | 23409132 | PLoS One | Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. | 2013 | Details |
| A34486 | 23339067 | Hepatology | Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents. | 2013 | Details |
| A34514 | 27335818 | ISRN Hepatol | Murine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |
| A34532 | 24695939 | Hepat Med | Treatment of nonalcoholic steatohepatitis with vitamins E and C: a pilot study. | 2013 | Details |
| A34545 | 23233000 | Surg Endosc | Resistin expression correlates with steatohepatitis in morbidly obese patients. | 2012 | Details |
| A34571 | 23172731 | J Magn Reson Imaging | Usefulness of Gd-EOB-DTPA-enhanced MR imaging in the evaluation of simple steatosis and nonalcoholic steatohepatitis. | 2012 | Details |
| A34575 | 23170052 | J Clin Biochem Nutr | Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis. | 2012 | Details |
| A34579 | 23152743 | PLoS One | Comprehensive miRNA expression analysis in peripheral blood can diagnose liver disease. | 2012 | Details |
| A34615 | 23056165 | PLoS One | Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism. | 2012 | Details |
| A34637 | 23007134 | Lab Invest | Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis. | 2012 | Details |
| A34654 | 22986647 | Obes Facts | Nonalcoholic steatohepatitis in bariatric patients with a diagnosis of obstructive sleep apnea. | 2012 | Details |
| A34662 | 22971151 | Hepatol Res | Pitavastatin ameliorated the progression of steatohepatitis in ovariectomized mice fed a high fat and high cholesterol diet. | 2012 | Details |
| A34680 | 22918204 | Acta Med Okayama | Water extract of Vitis coignetiae Pulliat leaves attenuates oxidative stress and inflammation in progressive NASH rats. | 2012 | Details |
| A34685 | 22882855 | Chin Med J (Engl) | Pioglitazone ameliorates nonalcoholic steatohepatitis by down-regulating hepatic nuclear factor-kappa B and cyclooxygenases-2 expression in rats. | 2012 | Details |
| A34756 | 22690069 | World J Gastroenterol | Leaky gut and the liver: a role for bacterial translocation in nonalcoholic steatohepatitis. | 2012 | Details |
| A34831 | 22487102 | Hepatol Res | Clinical and pathological progression of non-alcoholic steatohepatitis to hepatocellular carcinoma. | 2012 | Details |
| A34846 | 22442158 | Am J Physiol Gastrointest Liver Physiol | Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2. | 2012 | Details |
| A34859 | 22411067 | Lab Invest | Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis. | 2012 | Details |
| A34862 | 22404726 | J Viral Hepat | Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. | 2011 | Details |
| A34871 | 22363250 | Mar Drugs | Inhibitory effects of Ecklonia cava extract on high glucose-induced hepatic stellate cell activation. | 2011 | Details |
| A34874 | 22359532 | PLoS One | Serum vitamin D levels are not predictive of the progression of chronic liver disease in hepatitis C patients with advanced fibrosis. | 2012 | Details |
| A34884 | 22294490 | Phytother Res | Hepatoprotective effects of pycnogenol in a rat model of non-alcoholic steatohepatitis. | 2012 | Details |
| A34900 | 22245892 | J Hepatol | Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity. | 2012 | Details |
| A34908 | 22225648 | Am J Transplant | Long-term impact of liver transplantation on respiratory function and nutritional status in children and adults with cystic fibrosis. | 2012 | Details |
| A34967 | 22110414 | Case Rep Gastroenterol | Histological Remission during Corticosteroid Therapy of Overlapping Nonalcoholic Steatohepatitis and Autoimmune Hepatitis: Case Report and Literature Review. | 2011 | Details |
| A34970 | 22108052 | Biochem Biophys Res Commun | Nicotine induces fibrogenic changes in human liver via nicotinic acetylcholine receptors expressed on hepatic stellate cells. | 2011 | Details |
| A35005 | 21993925 | Hepatology | Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis. | 2011 | Details |
| A35007 | 21988197 | Hepatol Res | Angiotensinogen gene haplotype is associated with the prevalence of Japanese non-alcoholic steatohepatitis. | 2011 | Details |
| A35022 | 21933146 | Curr Pharm Des | Metabolic therapy: lessons from liver diseases. | 2011 | Details |
| A35029 | 21922031 | Therap Adv Gastroenterol | Glitazones for human nonalcoholic steatohepatitis. | 2011 | Details |
| A35053 | 21865094 | Surg Obes Relat Dis | Serologic predictors of nonalcoholic steatohepatitis in a population undergoing bariatric surgery. | 2011 | Details |
| A35059 | 21845516 | J Clin Immunol | Altered phenotype and functionality of circulating immune cells characterize adult patients with nonalcoholic steatohepatitis. | 2011 | Details |
| A35067 | 21818687 | Hepatol Int | Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis. | 2011 | Details |
| A35111 | 21711428 | Hepatol Res | Pharmacological therapy for non-alcoholic steatohepatitis: How efficient are thiazolidinediones? | 2011 | Details |
| A35112 | 21711427 | Hepatol Res | Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase. | 2011 | Details |
| A35167 | 21547909 | J Pathol | Increased production of sonic hedgehog by ballooned hepatocytes. | 2011 | Details |
| A35178 | 21520194 | Hepatology | A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C. | 2011 | Details |
| A35189 | 21497748 | Best Pract Res Clin Gastroenterol | Animal models for the study of hepatic fibrosis. | 2011 | Details |
| A35212 | 21435125 | Hepatol Res | Splenectomy reduces fibrosis and preneoplastic lesions with increased triglycerides and essential fatty acids in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. | 2011 | Details |
| A35236 | 21338455 | Hepatol Res | Late diagnosed Wilson disease with hepatic and neurological manifestations. | 2011 | Details |
| A35237 | 21338452 | Hepatol Res | Pharmacological therapy of nonalcoholic steatohepatitis. | 2011 | Details |