Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A45556 | 23929893 | Aging (Albany NY) | Lipid-induced hepatic insulin resistance. | 2013 | Details |
| A45571 | 23840101 | Mediators Inflamm | Influence of gut microbiota on subclinical inflammation and insulin resistance. | 2013 | Details |
| A45579 | 23797065 | Horm Res Paediatr | Best determinants of nonalcoholic fatty liver disease and intra-abdominal fat in prepubertal children born small for gestational age: ultrasound technique versus anthropometric data. | 2013 | Details |
| A45580 | 23796632 | Horm Res Paediatr | Possible misinterpretations of nonalcoholic fatty liver disease and intra-abdominal fat in prepubertal children born small for gestational age. | 2013 | Details |
| A45584 | 23772495 | Nihon Naika Gakkai Zasshi | [Diabetes mellitus related common medical disorders: recent progress in diagnosis and treatment. Topics: I. Pathophysiology, diagnosis and treatment; 1. Nonalcoholic fatty liver disease]. | 2013 | Details |
| A45586 | 23766126 | Endocrinology | Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice. | 2013 | Details |
| A45598 | 23720171 | Dtsch Med Wochenschr | [Diabetes and the liver]. | 2013 | Details |
| A45599 | 23715754 | Diabetes Care | Dual peroxisome proliferator-activated receptor α/δ agonist GFT505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects. | 2013 | Details |
| A45600 | 23715724 | Am J Physiol Endocrinol Metab | Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis. | 2013 | Details |
| A45604 | 23707366 | J Hepatol | Might some of the beneficial effects of the Mediterranean diet on non-alcoholic fatty liver disease be mediated by reduced iron stores? | 2013 | Details |
| A45605 | 23707363 | J Hepatol | Reply to: "might some of the beneficial effects of the Mediterranean diet on non-alcoholic fatty liver disease be mediated by reduced iron stores?". | 2013 | Details |
| A45607 | 23698242 | Med Sci Sports Exerc | Exercise reduces inflammation and oxidative stress in obesity-related liver diseases. | 2013 | Details |
| A45610 | 23685558 | Arterioscler Thromb Vasc Biol | Hepatic steatosis is associated with aortic valve sclerosis in the general population: the Study of Health in Pomerania (SHIP). | 2013 | Details |
| A45611 | 23680744 | Hosp Pract (1995) | Pleiotropic effects of thiazolidinediones: implications for the treatment of patients with type 2 diabetes mellitus. | 2013 | Details |
| A45622 | 23602251 | Nutr Res | Gly482Ser mutation impairs the effects of peroxisome proliferator-activated receptor γ coactivator-1α on decreasing fat deposition and stimulating phosphoenolpyruvate carboxykinase expression in hepatocytes. | 2013 | Details |
| A45625 | 23582593 | Curr Probl Pediatr Adolesc Health Care | Metabolic syndrome in pediatrics: old concepts revised, new concepts discussed. | 2013 | Details |
| A45646 | 23475416 | Endocr Rev | Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. | 2013 | Details |
| A45648 | 23471889 | Diabetes Metab Res Rev | Hepatic manifestations of metabolic syndrome. | 2013 | Details |
| A45649 | 23467323 | Am J Physiol Regul Integr Comp Physiol | Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats. | 2013 | Details |
| A45651 | 23448486 | Curr Pharm Des | Role of adiponectin in the metabolic syndrome: current perspectives on its modulation as a treatment strategy. | 2013 | Details |
| A45654 | 23440555 | J Gastroenterol | Insulin-related biomarkers and their relationship with hepatic fibrosis risk in patients with psoriasis, metabolic syndrome and non-alcoholic fatty liver disease. | 2013 | Details |
| A45657 | 23423574 | Diabetes | Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance. | 2013 | Details |
| A45679 | 23304111 | PPAR Res | Misregulation of PPAR Functioning and Its Pathogenic Consequences Associated with Nonalcoholic Fatty Liver Disease in Human Obesity. | 2012 | Details |
| A45681 | 23298629 | J Hepatol | Drug-induced liver injury in obesity. | 2013 | Details |
| A45684 | 23295629 | Food Chem Toxicol | Protective effects of matrine against progression of high-fructose diet-induced steatohepatitis by enhancing antioxidant and anti-inflammatory defences involving Nrf2 translocation. | 2013 | Details |
| A45693 | 23259217 | Lakartidningen | [Non-alcoholic fatty liver disease can cause permanent liver damage]. | 2013 | Details |
| A45707 | 23175050 | Hepatology | Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats. | 2013 | Details |
| A45709 | 23161873 | Endocrinology | The role of the carbohydrate response element-binding protein in male fructose-fed rats. | 2012 | Details |
| A45710 | 23156704 | J Zoo Wildl Med | Hemochromatosis and fatty liver disease: building evidence for insulin resistance in bottlenose dolphins (Tursiops truncatus). | 2012 | Details |
| A45713 | 23144998 | PLoS One | Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids. | 2012 | Details |
| A45723 | 23070526 | Sleep Breath | Obstructive sleep apnea and dyslipidemia: importance of the liver axis. | 2012 | Details |
| A45724 | 23069475 | J Hepatol | From lung to liver: how does airborne particulate matter trigger NASH and systemic insulin resistance? | 2012 | Details |
| A45727 | 23047983 | Am J Physiol Endocrinol Metab | Maternal androgen excess reduces placental and fetal weights, increases placental steroidogenesis, and leads to long-term health effects in their female offspring. | 2012 | Details |
| A45756 | 22923470 | Diabetes | Plasma levels of fetuin-A and hepatic enzymes and risk of type 2 diabetes in women in the U.S. | 2012 | Details |
| A45762 | 22882641 | Diabet Med | Fatty liver: cause or consequence. | 2012 | Details |
| A45763 | 22877991 | Biochim Biophys Acta | Physiological roles of phosphatidylethanolamine N-methyltransferase. | 2012 | Details |
| A45768 | 22858195 | Nutrition | Nonalcoholic fatty liver disease as a pro-resolution defective disorder. | 2012 | Details |
| A45775 | 22813567 | Diabetes Metab Syndr | Insulin resistance and alanine amino transaminase (ALT) levels in first degree relatives of type 2 diabetes mellitus. | 2012 | Details |
| A45779 | 22801247 | J Investig Med | Effect of insulin versus triple oral therapy on the progression of hepatic steatosis in type 2 diabetes. | 2012 | Details |
| A45781 | 22792473 | Int J Hepatol | Etiopathogenesis of nonalcoholic steatohepatitis: role of obesity, insulin resistance and mechanisms of hepatotoxicity. | 2012 | Details |
| A45792 | 22715101 | J Biol Chem | The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation. | 2012 | Details |
| A45796 | 22696577 | Am J Physiol Regul Integr Comp Physiol | Potential clinical translation of juvenile rodent inactivity models to study the onset of childhood obesity. | 2012 | Details |
| A45804 | 22652784 | Front Biosci (Landmark Ed) | Obesity-related hepatocellular carcinoma: roles of risk factors altered in obesity. | 2012 | Details |
| A45813 | 22612529 | J Vet Pharmacol Ther | Pharmacokinetics of pioglitazone in lean and obese cats. | 2012 | Details |
| A45817 | 22560205 | Cell Metab | Cell Metabolism 2012 focus on lipids and insulin resistance. | 2012 | Details |
| A45818 | 22553843 | Zhonghua Gan Zang Bing Za Zhi | [Study on dysmetabolism in patients with non-alcoholic fatty liver disease and its different combinations]. | 2011 | Details |
| A45822 | 22527892 | Endocrine | Anti-oxidant therapy in non-alcoholic fatty liver disease: the role of silymarin. | 2012 | Details |
| A45836 | 23798298 | Compr Physiol | Lack of exercise is a major cause of chronic diseases. | 2012 | Details |
| A45845 | 22425588 | Gastroenterology | Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. | 2012 | Details |
| A45853 | 22383493 | Am J Physiol Gastrointest Liver Physiol | When GLP-1 hits the liver: a novel approach for insulin resistance and NASH. | 2012 | Details |
| A45855 | 22371327 | Hepatology | Diagnostic accuracy of adipose insulin resistance index and visceral adiposity index for progressive liver histology and cardiovascular risk in nonalcoholic fatty liver disease. | 2012 | Details |
| A45881 | 22219592 | World J Gastroenterol | Impact of liver diseases on the development of type 2 diabetes mellitus. | 2011 | Details |
| A45885 | 22209682 | J Nutr Biochem | Oleic acid activates peroxisome proliferator-activated receptor δ to compensate insulin resistance in steatotic cells. | 2011 | Details |
| A45894 | 22166577 | Ann Hepatol | Hormone replacement therapy in menopausal women: risk factor or protection to nonalcoholic fatty liver disease? | 2012 | Details |
| A45897 | 22154323 | Metabolism | Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice. | 2011 | Details |
| A45902 | 22152375 | Zhonghua Gan Zang Bing Za Zhi | [Pancreatic derived factor (PANDER) and non-alcoholic fatty liver disease (NAFLD)]. | 2011 | Details |
| A45909 | 22130312 | Clin Chim Acta | Thyroid function in childhood obesity and metabolic comorbidity. | 2011 | Details |
| A45912 | 22122483 | Curr Pharm Biotechnol | Intestinal MicrobiOMICS to define health and disease in human and mice. | 2012 | Details |
| A45916 | 22095841 | Hepatology | Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice. | 2012 | Details |
| A45917 | 22093451 | Liver Int | Understanding the relationship between PNPLA3, NAFLD and insulin resistance: do ethnic differences bring more questions or more answers? | 2011 | Details |
| A45929 | 22005190 | Adv Cardiol | Metabolic disorders associated with obstructive sleep apnea in adults. | 2011 | Details |
| A45947 | 21904679 | Biochem Res Int | The increased activity of liver lysosomal lipase in nonalcoholic Fatty liver disease contributes to the development of hepatic insulin resistance. | 2011 | Details |
| A45950 | 21898494 | Hepatology | Where are we in the search for noninvasive nonalcoholic steatohepatitis biomarkers? | 2011 | Details |
| A45961 | 21832111 | J Clin Endocrinol Metab | Metformin and/or clomiphene do not adversely affect liver or renal function in women with polycystic ovary syndrome. | 2011 | Details |
| A45966 | 21805747 | Zhonghua Gan Zang Bing Za Zhi | [The relationship between nonalcoholic fatty liver disease and polycystic ovarian syndrome]. | 2011 | Details |
| A45968 | 21788578 | Diabetes | The metabolically benign and malignant fatty liver. | 2011 | Details |
| A45972 | 21770296 | Nihon Naika Gakkai Zasshi | [The cutting-edge of medicine; clinical and molecular pathology of type 2 diabetic liver]. | 2011 | Details |
| A45988 | 21713308 | Cardiovasc J Afr | Serving diabetes and cardiology: round three of the South African diabetologist/cardiologist debate. | 2011 | Details |
| A45994 | 21701901 | Hepatol Int | Murine gamma herpes virus 68 infection promotes fatty liver formation and hepatic insulin resistance in C57BL/6J mice. | 2011 | Details |
| A45996 | 21697185 | Alcohol Alcohol | Alcoholic and non-alcoholic fatty liver in adolescents: a worrisome convergence. | 2011 | Details |
| A45999 | 21661508 | Diabetes Self Manag | High-fructose corn syrup. What's all the fuss about? | 2011 | Details |
| A46003 | 21640324 | Am J Med | Hyperinsulinemia in nonalcoholic fatty liver disease in nondiabetic adults. | 2011 | Details |
| A46011 | 21564446 | Int J Clin Pract | Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study. | 2011 | Details |
| A46017 | 21536711 | Endocr Rev | Genetic syndromes of severe insulin resistance. | 2011 | Details |
| A46021 | 21520192 | Hepatology | Insulin resistance links nonalcoholic fatty liver to cardiovascular diseases. | 2011 | Details |
| A46026 | 21494141 | Curr Opin Lipidol | Hepatic fatty acid partitioning. | 2011 | Details |
| A46028 | 21488942 | J Gastroenterol Hepatol | SREBP-2: a link between insulin resistance, hepatic cholesterol, and inflammation in NASH. | 2011 | Details |
| A46031 | 21480350 | Hepatology | Insulin sensitizers in nonalcoholic steatohepatitis. | 2011 | Details |
| A46032 | 21476910 | Expert Rev Gastroenterol Hepatol | Relevance of TNF-α gene polymorphisms in nonalcoholic fatty liver disease. | 2011 | Details |
| A46038 | 21465511 | Hepatology | Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. | 2011 | Details |
| A46040 | 21454445 | Am J Physiol Gastrointest Liver Physiol | Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet. | 2011 | Details |
| A46043 | 21441697 | Circ J | Prevention of atherosclerosis in overweight/obese patients. - In need of novel multi-targeted approaches-. | 2011 | Details |
| A46045 | 21435084 | Helicobacter | The association between Helicobacter pylori infection and insulin resistance: a systematic review. | 2011 | Details |
| A46059 | 21366813 | Pediatr Diabetes | Use of metformin in pediatric age. | 2011 | Details |
| A46065 | 21332536 | J Gastroenterol Hepatol | Should all patients with nonalcoholic fatty liver disease undergo oral glucose tolerance test? | 2011 | Details |
| A46067 | 21303949 | Endocrinology | Growth hormone-dependent pathogenesis of human hepatic steatosis in a novel mouse model bearing a human hepatocyte-repopulated liver. | 2011 | Details |
| A46068 | 21300117 | J Hepatol | Effect of treatment with polyunsaturated fatty acids on HCV- or diet-induced fatty liver. | 2011 | Details |
| A46085 | 21194387 | Antioxid Redox Signal | Adipokines and redox signaling: impact on fatty liver disease. | 2011 | Details |
| A46087 | 21167426 | Ann Pathol | [Non-alcoholic fatty liver disease]. | 2010 | Details |
| A46094 | 21142633 | Future Cardiol | Sugar-sweetened beverages and hypertension. | 2010 | Details |
| A46099 | 21105450 | Vnitr Lek | [Complications of obesity--pathogenesis]. | 2010 | Details |
| A46100 | 21105109 | Hepatology | Therapeutic trials in nonalcoholic steatohepatitis: insulin sensitizers and related methodological issues. | 2010 | Details |
| A46117 | 20967760 | Hepatology | Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease. | 2010 | Details |
| A46119 | 20962018 | J Clin Endocrinol Metab | The metabolic phenotype of Prader-Willi syndrome (PWS) in childhood: heightened insulin sensitivity relative to body mass index. | 2010 | Details |
| A46125 | 20880166 | J Gastroenterol Hepatol | Failure of islet β-cell compensation for insulin resistance causes type 2 diabetes: what causes non-alcoholic fatty liver disease and non-alcoholic steatohepatitis? | 2010 | Details |
| A46126 | 20879883 | N Engl J Med | Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A46134 | 20822767 | Am J Obstet Gynecol | Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring. | 2010 | Details |
| A46139 | 20807839 | Am J Physiol Endocrinol Metab | A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain. | 2010 | Details |
| A46141 | 20799351 | Hepatology | Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. | 2010 | Details |
| A46142 | 20798858 | J Obes | Long-term effects of metformin and lifestyle modification on nonalcoholic Fatty liver disease obese adolescents. | 2010 | Details |