Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04199 | 33719959 | Curr Pharm Des | The Effect of Metformin on Aminotransferase Levels, Metabolic Parameters and Body Mass Index in Nonalcoholic Fatty Liver Disease Patients: A Metaanalysis. | 2021 | Details |
| A04205 | 33715205 | Clin Endocrinol (Oxf) | Relationship between de novo lipogenesis and serum sex hormone binding globulin in humans. | 2021 | Details |
| A04209 | 33712680 | Sci Rep | Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma. | 2021 | Details |
| A04211 | 33711964 | BMC Pediatr | Clinical characteristics and risk factors of nonalcoholic fatty liver disease in children with obesity. | 2021 | Details |
| A04225 | 33708180 | Front Microbiol | Resveratrol Improves Liver Steatosis and Insulin Resistance in Non-alcoholic Fatty Liver Disease in Association With the Gut Microbiota. | 2021 | Details |
| A04232 | 33705650 | Diabetes Metab J | Distinct Dose-Dependent Association of Free Fatty Acids with Diabetes Development in Nonalcoholic Fatty Liver Disease Patients. | 2021 | Details |
| A04233 | 33704100 | Clin Transl Gastroenterol | Individualized Polygenic Risk Score Identifies NASH in the Eastern Asia Region: A Derivation and Validation Study. | 2021 | Details |
| A04245 | 33691757 | Diabetol Metab Syndr | Beneficial effect of omarigliptin on diabetic patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis. | 2021 | Details |
| A04246 | 33691721 | Nutr Metab (Lond) | Integrative proteomic and lipidomic analysis of Kaili Sour Soup-mediated attenuation of high-fat diet-induced nonalcoholic fatty liver disease in a rat model. | 2021 | Details |
| A04250 | 33689525 | Arch Physiol Biochem | Effects of lacto-ovo-vegetarian diet vs. standard-weight-loss diet on obese and overweight adults with non-alcoholic fatty liver disease: a randomised clinical trial. | 2021 | Details |
| A04254 | 33688229 | Diabetes Metab Syndr Obes | Risk Factors Screening for Gestational Diabetes Mellitus Heterogeneity in Chinese Pregnant Women: A Case-Control Study. | 2021 | Details |
| A04267 | 33684566 | Biochim Biophys Acta Mol Cell Biol Lipids | GDF11 rapidly increases lipid accumulation in liver cancer cells through ALK5-dependent signaling. | 2021 | Details |
| A04268 | 33683797 | Int J Clin Pract | The association of the steatosis severity, NAFLD fibrosis score and FIB-4 index with atherogenic dyslipidaemia in adult patients with NAFLD: A cross-sectional study. | 2021 | Details |
| A04269 | 33681678 | Hepatol Commun | High-Fat Diet Modulates Hepatic Amyloid β and Cerebrosterol Metabolism in the Triple Transgenic Mouse Model of Alzheimer's Disease. | 2020 | Details |
| A04271 | 33681089 | Can J Gastroenterol Hepatol | NAFLD, Insulin Resistance, and Diabetes Mellitus Type 2. | 2021 | Details |
| A04274 | 33680375 | Caspian J Intern Med | Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges. | 2020 | Details |
| A04279 | 33679386 | Front Pharmacol | Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice. | 2021 | Details |
| A04285 | 33678036 | Hum Exp Toxicol | Early intervention with probiotics and metformin alleviates liver injury in NAFLD rats via targeting gut microbiota dysbiosis and p-AKT/mTOR/LC-3II pathways. | 2021 | Details |
| A04288 | 33676874 | Surg Obes Relat Dis | The metabolic and liver-related outcomes of bariatric surgery in adult patients with insulin-treated type 2 diabetes and nonalcoholic fatty liver disease at high risk of liver fibrosis. | 2020 | Details |
| A04301 | 33672073 | Nutrients | Energy Expenditure Improved Risk Factors Associated with Renal Function Loss in NAFLD and MetS Patients. | 2021 | Details |
| A04302 | 33671926 | Int J Mol Sci | Sarcopenic Obesity in Liver Cirrhosis: Possible Mechanism and Clinical Impact. | 2021 | Details |
| A04303 | 33671880 | Biomedicines | Immunomodulatory Role of Urolithin A on Metabolic Diseases. | 2021 | Details |
| A04307 | 33671547 | Int J Mol Sci | Association of Adipose Tissue and Adipokines with Development of Obesity-Induced Liver Cancer. | 2021 | Details |
| A04313 | 33669288 | Int J Environ Res Public Health | Relationships between Socioeconomic Status, Handgrip Strength, and Non-Alcoholic Fatty Liver Disease in Middle-Aged Adults. | 2021 | Details |
| A04317 | 33667726 | Mol Metab | Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction. | 2021 | Details |
| A04318 | 33667513 | Life Sci | Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD. | 2021 | Details |
| A04324 | 33665291 | Pract Lab Med | Low levels of spexin and adiponectin may predict insulin resistance in patients with non-alcoholic fatty liver. | 2021 | Details |
| A04325 | 33665203 | Front Nutr | The Impact of Macronutrient Intake on Non-alcoholic Fatty Liver Disease (NAFLD): Too Much Fat, Too Much Carbohydrate, or Just Too Many Calories? | 2021 | Details |
| A04326 | 33665176 | Front Pediatr | Liver Enzymes Correlate With Metabolic Syndrome, Inflammation, and Endothelial Dysfunction in Prepubertal Children With Obesity. | 2021 | Details |
| A04331 | 33664225 | Cell Death Dis | Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN. | 2021 | Details |
| A04332 | 33664007 | Arab J Gastroenterol | Short-term orlistat therapy improves fatty infiltration indices and liver fibrosis scores in patients with non-alcoholic fatty liver disease and metabolic syndrome. | 2021 | Details |
| A04333 | 33662773 | Clin Res Hepatol Gastroenterol | Low levels of Lysosomal Acid Lipase (LAL) activity increases necroinflammation in adult patients with biopsy-proven metabolic associated fatty liver disease. | 2021 | Details |
| A04338 | 33658534 | Sci Rep | Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men. | 2021 | Details |
| A04339 | 33658485 | Cell Death Dis | WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1. | 2021 | Details |
| A04340 | 33658438 | Endocr J | Association between serum 25-hydroxy vitamin D level and metabolic associated fatty liver disease (MAFLD)-a population-based study. | 2021 | Details |
| A04352 | 33652261 | Biomed Pharmacother | Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury. | 2021 | Details |
| A04354 | 33650781 | Physiol Rep | Serum fetuin-A and Ser312 phosphorylated fetuin-A responses and markers of insulin sensitivity after a single bout of moderate intensity exercise. | 2021 | Details |
| A04360 | 33647942 | Endocrinology | Hepatic Igf1-Deficiency Protects Against Atherosclerosis in Female Mice. | 2021 | Details |
| A04366 | 33647280 | Gastroenterology | Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target. | 2021 | Details |
| A04367 | 33647205 | Chem Res Toxicol | LXRα/β Antagonism Protects against Lipid Accumulation in the Liver but Increases Plasma Cholesterol in Rhesus Macaques. | 2021 | Details |
| A04384 | 33640265 | J Diabetes Complications | Serum uric acid is positively associated with the prevalence of nonalcoholic fatty liver in non-obese type 2 diabetes patients in a Chinese population. | 2021 | Details |
| A04385 | 33640247 | Phytomedicine | A network pharmacology approach: Inhibition of the NF-κB signaling pathway contributes to the NASH preventative effect of an Oroxylum indicum seed extract in oleic acid-stimulated HepG2 cells and high-fat diet-fed rats. | 2021 | Details |
| A04386 | 33639194 | Eur J Pharmacol | Research progress in use of traditional Chinese medicine monomer for treatment of non-alcoholic fatty liver disease. | 2021 | Details |
| A04395 | 33636024 | Hepatology | Sirtuin 2 Prevents Liver Steatosis and Metabolic Disorders by Deacetylation of Hepatocyte Nuclear Factor 4α. | 2021 | Details |
| A04402 | 33632113 | Endocr Metab Immune Disord Drug Targets | Effects of Metformin-Single Therapy on the Level of Inflammatory Markers in Serum of Non-Obese T2DM Patients with NAFLD. | 2022 | Details |
| A04409 | 33630217 | Dig Dis Sci | Cadmium Exposure in Young Adulthood Is Associated with Risk of Nonalcoholic Fatty Liver Disease in Midlife. | 2021 | Details |
| A04418 | 33626072 | PLoS One | Characteristics of bile acid composition in high fat diet-induced nonalcoholic fatty liver disease in obese diabetic rats. | 2021 | Details |
| A04429 | 33618924 | Nutr Metab Cardiovasc Dis | Serum leptin as a mediator of the influence of insulin resistance on hepatic steatosis in youths with excess adiposity. | 2021 | Details |
| A04441 | 33615637 | Anim Sci J | Complement C3 participates in the development of goose fatty liver potentially by regulating the expression of FASN and ETNK1. | 2021 | Details |
| A04443 | 33615207 | JHEP Rep | NASH-related increases in plasma bile acid levels depend on insulin resistance. | 2020 | Details |
| A04451 | 33611063 | Int Immunopharmacol | Hyperoside attenuates non-alcoholic fatty liver disease through targeting Nr4A1 in macrophages. | 2021 | Details |
| A04458 | 33608323 | Dis Model Mech | High-dose vitamin B1 therapy prevents the development of experimental fatty liver driven by overnutrition. | 2021 | Details |
| A04460 | 33608033 | Nutr Metab (Lond) | Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals. | 2021 | Details |
| A04474 | 33603666 | Front Pharmacol | The Role of Bone Morphogenetic Protein 9 in Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A04478 | 33601426 | Exp Clin Endocrinol Diabetes | Impact of Non-Alcoholic Fatty Liver Disease on Metabolic Comorbidities in Type 2 Diabetes Mellitus. | 2021 | Details |
| A04489 | 33598160 | Food Sci Nutr | The protective effect of sulforaphane on type II diabetes induced by high-fat diet and low-dosage streptozotocin. | 2020 | Details |
| A04492 | 33597157 | Gut | Safety and efficacy of hydrothermal duodenal mucosal resurfacing in patients with type 2 diabetes: the randomised, double-blind, sham-controlled, multicentre REVITA-2 feasibility trial. | 2021 | Details |
| A04495 | 33596938 | J Transl Med | Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD. | 2021 | Details |
| A04497 | 33596132 | Metab Syndr Relat Disord | When They're Done Growing, Don't Forget They May Still Need Growth Hormone. | 2021 | Details |
| A04502 | 33595214 | Isr Med Assoc J | The Impact of Ramadan Fasting on Fatty Liver Disease Severity: A Retrospective Case Control Study from Israel. | 2021 | Details |
| A04506 | 33594581 | Diabetes Ther | Efficacy and Safety of Luseogliflozin in Patients with Type 2 Diabetes Complicated by Hepatic Dysfunction: A Single-Site, Single-Arm, Open-Label, Exploratory Trial. | 2021 | Details |
| A04514 | 33592199 | Life Sci | Non-alcoholic fatty liver disease: An overview of risk factors, pathophysiological mechanisms, diagnostic procedures, and therapeutic interventions. | 2021 | Details |
| A04515 | 33591626 | J Cell Mol Med | Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity. | 2021 | Details |
| A04521 | 33588102 | Mol Metab | Stress kinases in the development of liver steatosis and hepatocellular carcinoma. | 2021 | Details |
| A04525 | 33586811 | J Hum Nutr Diet | Association of dietary insulinaemic potential and odds of non-alcoholic fatty liver disease among adults: A case-control study. | 2021 | Details |
| A04530 | 33586120 | Diabetes Ther | Empagliflozin Improves Liver Steatosis and Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. | 2021 | Details |
| A04534 | 33585009 | Gastroenterol Hepatol Bed Bench | Showing NAFLD, as a key connector disease between Alzheimer's disease and diabetes via analysis of systems biology. | 2020 | Details |
| A04535 | 33584988 | World J Hepatol | Shifting perspectives - interplay between non-alcoholic fatty liver disease and insulin resistance in lean individuals. | 2021 | Details |
| A04546 | 33583577 | Clin Ther | Therapy for Nonalcoholic Fatty Liver Disease: Current Options and Future Directions. | 2021 | Details |
| A04562 | 33579423 | Adv Cancer Res | NAFLD-related HCC. | 2021 | Details |
| A04565 | 33578702 | Antioxidants (Basel) | Mechanisms of Non-Alcoholic Fatty Liver Disease in the Metabolic Syndrome. A Narrative Review. | 2021 | Details |
| A04567 | 33578449 | Biotechnol Appl Biochem | An insight into the role of telmisartan as PPAR-γ/α dual activator in the management of nonalcoholic fatty liver disease. | 2021 | Details |
| A04568 | 33578292 | Biochem Biophys Res Commun | Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1. | 2021 | Details |
| A04577 | 33574818 | Front Immunol | Predicting Non-Alcoholic Fatty Liver Disease Progression and Immune Deregulations by Specific Gene Expression Patterns. | 2021 | Details |
| A04584 | 33572810 | Nutrients | Krill Oil Supplementation Reduces Exacerbated Hepatic Steatosis Induced by Thermoneutral Housing in Mice with Diet-Induced Obesity. | 2021 | Details |
| A04602 | 33567543 | Nutrients | Implication between Genetic Variants from APOA5 and ZPR1 and NAFLD Severity in Patients with Hypertriglyceridemia. | 2021 | Details |
| A04611 | 33564651 | Clin Nutr Res | Probiotic Yogurt Fortified with Vitamin D Can Improve Glycemic Status in Non-Alcoholic Fatty Liver Disease Patients: a Randomized Clinical Trial. | 2021 | Details |
| A04629 | 33557355 | Life (Basel) | Sarcopenic Obesity in Non-Alcoholic Fatty Liver Disease-The Union of Two Culprits. | 2021 | Details |
| A04642 | 33554072 | iScience | Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega oxidation. | 2021 | Details |
| A04645 | 33553660 | JGH Open | Eradication of hepatitis C virus with direct-acting antivirals improves glycemic control in diabetes: A multicenter study. | 2020 | Details |
| A04658 | 33549451 | Nutr Metab Cardiovasc Dis | Apolipoprotein A5 controls fructose-induced metabolic dysregulation in mice. | 2020 | Details |
| A04662 | 33548387 | J Hepatol | FOXA3 induction under endoplasmic reticulum stress contributes to non-alcoholic fatty liver disease. | 2021 | Details |
| A04670 | 33546130 | Nutrients | Dietary Polyphenols and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04674 | 33545428 | Cell Mol Gastroenterol Hepatol | SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04675 | 33545391 | Mol Metab | Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH. | 2021 | Details |
| A04677 | 33545051 | Cell Metab | Metabolic stress drives sympathetic neuropathy within the liver. | 2021 | Details |
| A04684 | 33542919 | Biomed Res Int | Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice. | 2021 | Details |
| A04690 | 33541129 | Exp Biol Med (Maywood) | Effect of vitamin D3 supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice. | 2021 | Details |
| A04694 | 33537464 | Biochem Biophys Rep | A high methionine and low folate diet alters glucose homeostasis and gut microbiome. | 2021 | Details |
| A04706 | 33534958 | ESC Heart Fail | Non-alcoholic fatty liver disease and heart failure with preserved ejection fraction: from pathophysiology to practical issues. | 2021 | Details |
| A04709 | 33532874 | Eur J Nutr | The effects of Chlorella supplementation on glycemic control, lipid profile and anthropometric measures on patients with type 2 diabetes mellitus. | 2021 | Details |
| A04725 | 33526807 | Lab Invest | NLRP3 deficiency did not attenuate NASH development under high fat calorie diet plus high fructose and glucose in drinking water. | 2021 | Details |
| A04740 | 33518166 | Gastroenterol Clin North Am | The Impact of Dietary Patterns and Nutrition in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04750 | 33515696 | Cell Signal | Coordinated regulation of miR-27 by insulin/CREB/Hippo contributes to insulin resistance. | 2021 | Details |
| A04761 | 33513642 | Horm Metab Res | Insulin Resistance and Non-Alcoholic Fatty Liver Disease in Premenopausal Women with Metabolic Syndrome. | 2021 | Details |
| A04764 | 33513383 | J Steroid Biochem Mol Biol | Long-term androgen excess induces insulin resistance and non-alcoholic fatty liver disease in PCOS-like rats. | 2021 | Details |
| A04783 | 33506572 | Liver Int | Fibroblast Growth Factor 19: Potential modulation of hepatic metabolism for the treatment of non-alcoholic fatty liver disease. | 2021 | Details |
| A04784 | 33505944 | Can J Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases: The Heart of the Matter. | 2021 | Details |
| A04786 | 33505894 | Pediatr Gastroenterol Hepatol Nutr | Changes in Liver Enzymes and Metabolic Profile in Adolescents with Fatty Liver following Exercise Interventions. | 2021 | Details |
| A04787 | 33505505 | Evid Based Complement Alternat Med | A Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology. | 2021 | Details |