Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Tumor necrosis factor1477 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24080 | 23256442 | J Med Food | Dandelion leaf extract protects against liver injury induced by methionine- and choline-deficient diet in mice. | 2012 | Details |
| A24092 | 23236228 | World J Gastroenterol | Genetic and epigenetic variants influencing the development of nonalcoholic fatty liver disease. | 2012 | Details |
| A24120 | 23212097 | Lab Invest | Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome. | 2012 | Details |
| A24135 | 25755455 | J Clin Exp Hepatol | A Randomized Controlled Trial Comparing Efficacy of Pentoxifylline and Pioglitazone on Metabolic Factors and Liver Histology in Patients with Non-alcoholic Steatohepatitis. | 2012 | Details |
| A24152 | 23175777 | J Lipid Res | Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat. | 2012 | Details |
| A24156 | 23174488 | Clin Biochem | Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease. | 2012 | Details |
| A24167 | 23158500 | J Crohns Colitis | Risk factors of non-alcoholic fatty liver disease in patients with inflammatory bowel disease. | 2012 | Details |
| A24168 | 23158405 | J Surg Res | Lysophospholipid variants in hepatocellular carcinoma. | 2012 | Details |
| A24189 | 23139599 | World J Gastroenterol | Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease. | 2012 | Details |
| A24207 | 23123425 | Food Chem Toxicol | Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils. | 2012 | Details |
| A24217 | 23112047 | J Biol Chem | Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model. | 2012 | Details |
| A24260 | 23067270 | Hepatol Res | Serum biomarkers in type 2 diabetic patients with non-alcoholic steatohepatitis and advanced fibrosis. | 2012 | Details |
| A24265 | 23066023 | J Biol Chem | Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production. | 2012 | Details |
| A24266 | 23065020 | J Gastroenterol | The effect of etanercept on hepatic fibrosis risk in patients with non-alcoholic fatty liver disease, metabolic syndrome, and psoriasis. | 2012 | Details |
| A24278 | 23044079 | Dig Liver Dis | The pro-inflammatory action of tumour necrosis factor-α in non-alcoholic steatohepatitis is independent of the NSMAF gene product. | 2012 | Details |
| A24279 | 23042833 | Nutr Clin Pract | Anthropometric measures of visceral and subcutaneous fat are important in the determination of metabolic dysregulation in boys and girls at risk for nonalcoholic fatty liver disease. | 2012 | Details |
| A24286 | 23038002 | J Toxicol Sci | Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models. | 2012 | Details |
| A24314 | 23009757 | Eur Cytokine Netw | TNF-α messenger ribonucleic acid (mRNA) in patients with nonalcoholic steatohepatitis. | 2013 | Details |
| A24383 | 22952059 | Mol Med | Female mice are more susceptible to nonalcoholic fatty liver disease: sex-specific regulation of the hepatic AMP-activated protein kinase-plasminogen activator inhibitor 1 cascade, but not the hepatic endotoxin response. | 2012 | Details |
| A24390 | 22941955 | Hepatology | Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model. | 2013 | Details |
| A24424 | 22912545 | World J Gastroenterol | Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease. | 2012 | Details |
| A24452 | 22878918 | Dig Dis Sci | Probucol ameliorates the development of nonalcoholic steatohepatitis in rats fed high-fat diets. | 2012 | Details |
| A24473 | 22858825 | Mol Med Rep | Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-α and SREBP-1c. | 2012 | Details |
| A24478 | 22855443 | Dongwuxue Yanjiu | [Effects of resistin on hepatic fibrosis: possible mechanisms in non-alcoholic fatty liver disease in in vitro and in vivo]. | 2012 | Details |
| A24481 | 22851489 | J Clin Endocrinol Metab | Increased tenascin C and Toll-like receptor 4 levels in visceral adipose tissue as a link between inflammation and extracellular matrix remodeling in obesity. | 2012 | Details |
| A24494 | 22841522 | Metabolism | Helicobacter pylori infection in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24502 | 22827449 | Clin Sci (Lond) | Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model. | 2013 | Details |
| A24545 | 22768838 | Cell Metab | Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling. | 2012 | Details |
| A24597 | 22710359 | Int J Mol Med | Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: analysis of isolated hepatic stellate cells. | 2012 | Details |
| A24600 | 22706738 | Turk J Gastroenterol | Effects of probiotics on methionine choline deficient diet-induced steatohepatitis in rats. | 2012 | Details |
| A24621 | 22683933 | Toxicol In Vitro | Effects of palmitic acid on TNF-α-induced cytotoxicity in SK-Hep-1 cells. | 2012 | Details |
| A24629 | 22673924 | Int J Vitam Nutr Res | Therapeutic effect of metformin and vitamin E versus prescriptive diet in obese adolescents with fatty liver. | 2011 | Details |
| A24637 | 22668639 | J Hepatol | Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis. | 2012 | Details |
| A24642 | 22658783 | Cytokine | Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24656 | 25755423 | J Clin Exp Hepatol | Non-invasive Diagnosis of Fibrosis in Non-alcoholic Fatty Liver Disease. | 2012 | Details |
| A24658 | 25755421 | J Clin Exp Hepatol | Non-alcoholic Fatty Liver Disease: East Versus West. | 2012 | Details |
| A24688 | 22609053 | Trends Endocrinol Metab | Role of ceramides in nonalcoholic fatty liver disease. | 2012 | Details |
| A24691 | 22594108 | J Tradit Chin Med | Study on effects of zhi zi (fructus gardeniae) on non-alcoholic fatty liver disease in the rat. | 2012 | Details |
| A24701 | 22583683 | Hepatol Res | Suppression of autophagy sensitizes Kupffer cells to endotoxin. | 2012 | Details |
| A24728 | 22554494 | Brain Behav Immun | Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice. | 2012 | Details |
| A24732 | 22551412 | J Med Food | Raspberry ketone protects rats fed high-fat diets against nonalcoholic steatohepatitis. | 2012 | Details |
| A24740 | 22546234 | Eur J Pharmacol | Effect of valsartan on the pathological progression of hepatic fibrosis in rats with type 2 diabetes. | 2012 | Details |
| A24764 | 22525431 | Lab Invest | Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function. | 2012 | Details |
| A24779 | 22505328 | Hepatology | Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. | 2012 | Details |
| A24806 | 22469867 | Int J Mol Med | Therapeutic effects of angiotensin II type 1 receptor blocker, irbesartan, on non-alcoholic steatohepatitis using FLS-ob/ob male mice. | 2012 | Details |
| A24814 | 22468051 | Indian J Clin Biochem | Role of cytokines in the pathogenesis of non-alcoholic Fatty liver disease. | 2011 | Details |
| A24823 | 22464705 | Zhonghua Gan Zang Bing Za Zhi | [The effect of resistin on nuclear factor-kB and tumor necrosis factor-a expression in hepatic steatosis]. | 2012 | Details |
| A24831 | 22451385 | Biosci Biotechnol Biochem | Effects of lotus root (the edible rhizome of Nelumbo nucifera) on the deveolopment of non-alcoholic fatty liver disease in obese diabetic db/db mice. | 2012 | Details |
| A24836 | 22444524 | Dig Liver Dis | Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome. | 2012 | Details |
| A24852 | 22432744 | J Gastroenterol Hepatol | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | Details |
| A24900 | 22380754 | BMC Gastroenterol | Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24913 | 22367065 | Dig Dis Sci | Innate immune reactivity of the ileum-liver axis in nonalcoholic steatohepatitis. | 2012 | Details |
| A24940 | 22334337 | Hepatology | Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice. | 2012 | Details |
| A24953 | 22319522 | Exp Diabetes Res | Pentoxifylline attenuates methionine- and choline-deficient-diet-induced steatohepatitis by suppressing TNF-α expression and endoplasmic reticulum stress. | 2012 | Details |
| A24968 | 22297845 | Nature | Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. | 2012 | Details |
| A24975 | 22290395 | Hepatology | Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis. | 2012 | Details |
| A24976 | 22288305 | Eur Rev Med Pharmacol Sci | The psoriatic patient profile for infliximab. | 2011 | Details |
| A24997 | 22265683 | Dig Liver Dis | Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property. | 2012 | Details |
| A25026 | 22236001 | Clin Exp Immunol | Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells. | 2012 | Details |
| A25047 | 22215946 | World J Gastroenterol | IκB kinase-beta inhibitor attenuates hepatic fibrosis in mice. | 2011 | Details |
| A25063 | 24331173 | Obes Res Clin Pract | Hepatic tumor necrosis factor-α, leptin and adiponectin expression in morbid obese patients: Clinicopathological correlations. | 2013 | Details |
| A25082 | 22183953 | Hepatology | Hepatic endothelin-1 and endocannabinoids-dependent effects of hyperleptinemia in nonalcoholic steatohepatitis-cirrhotic rats. | 2012 | Details |
| A25120 | 22155236 | Biochem Biophys Res Commun | Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model. | 2011 | Details |
| A25162 | 22121808 | Zhongguo Zhong Yao Za Zhi | [Effect of total alkaloids of Rubus alceaefolius on oxidative stress in rats with non-alcoholic fatty liver disease]. | 2011 | Details |
| A25176 | 22111040 | Diabetes Metab J | Dietary oleate has beneficial effects on every step of non-alcoholic Fatty liver disease progression in a methionine- and choline-deficient diet-fed animal model. | 2011 | Details |
| A25184 | 22108588 | Exp Cell Res | A methionine-choline-deficient diet elicits NASH in the immunodeficient mouse featuring a model for hepatic cell transplantation. | 2011 | Details |
| A25191 | 22103753 | Pharm Biol | Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease. | 2011 | Details |
| A25199 | 22098164 | J Gastroenterol Hepatol | Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export. | 2012 | Details |
| A25201 | 22097889 | J Gastroenterol Hepatol | Association of tumor necrosis factor-α gene promoter polymorphism at sites -308 and -238 with non-alcoholic fatty liver disease: a meta-analysis. | 2012 | Details |
| A25213 | 22087354 | World J Diabetes | A defect in the activities of Δ and Δ desaturases and pro-resolution bioactive lipids in the pathobiology of non-alcoholic fatty liver disease. | 2011 | Details |
| A25237 | 22064320 | Lab Invest | A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein. | 2011 | Details |
| A25243 | 22053378 | Zhonghua Gan Zang Bing Za Zhi | [The effects of curcumin derivative on experimental steatohepatitis]. | 2011 | Details |
| A25245 | 22050747 | Curr Med Chem | Fatty liver and ischemia/reperfusion: are there drugs able to mitigate injury? | 2011 | Details |
| A25256 | 22037452 | Biochem Biophys Res Commun | 17β-Estradiol attenuates saturated fatty acid diet-induced liver injury in ovariectomized mice by up-regulating hepatic senescence marker protein-30. | 2011 | Details |
| A25273 | 22018861 | Br J Nutr | Toll-like receptors 1-9 are elevated in livers with fructose-induced hepatic steatosis. | 2011 | Details |
| A25298 | 21986673 | Eur J Nutr | Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα. | 2011 | Details |
| A25307 | 21977865 | J Tradit Chin Med | Effects of yinchenhao decoction (see text) for non-alcoholic steatohepatitis in rats and study of the mechanism. | 2011 | Details |
| A25338 | 21948338 | Dig Dis Sci | Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease. | 2011 | Details |
| A25379 | 21907177 | Am J Pathol | Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet. | 2011 | Details |
| A25384 | 21903748 | J Pharmacol Exp Ther | Serotonin receptor type 3 antagonists improve obesity-associated fatty liver disease in mice. | 2011 | Details |
| A25385 | 21901256 | Dig Dis Sci | Bifidobacterium longum with fructo-oligosaccharides in patients with non alcoholic steatohepatitis. | 2011 | Details |
| A25403 | 21886908 | Sci Pharm | Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines. | 2011 | Details |
| A25410 | 21881966 | Metab Brain Dis | Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. | 2011 | Details |
| A25415 | 25755327 | J Clin Exp Hepatol | Nuclear Factor High-mobility Group Box1 Mediating the Activation of Toll-like Receptor 4 Signaling in Hepatocytes in the Early Stage of Non-alcoholic Fatty Liver Disease in Mice. | 2011 | Details |
| A25431 | 21853259 | Environ Health Prev Med | Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. | 2011 | Details |
| A25453 | 21817060 | Am J Physiol Gastrointest Liver Physiol | Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosis. | 2011 | Details |
| A25459 | 21809356 | Hepatology | Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. | 2011 | Details |
| A25480 | 21787451 | Br J Nutr | Protective effects of fractional extracts from Panellus serotinus on non-alcoholic fatty liver disease in obese, diabetic db/db mice. | 2011 | Details |
| A25519 | 21748768 | Hepatology | Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis. | 2011 | Details |
| A25520 | 21748765 | Hepatology | Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial. | 2011 | Details |
| A25542 | 21733354 | Chang Gung Med J | Disrupted hepatic adiponectin signaling impairs liver regeneration of steatotic rats. | 2011 | Details |
| A25570 | 21703208 | J Hepatol | DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH. | 2011 | Details |
| A25611 | 21649732 | J Gastroenterol Hepatol | Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. | 2012 | Details |
| A25653 | 21587068 | Curr Opin Clin Nutr Metab Care | The 5-lipoxygenase/leukotriene pathway in obesity, insulin resistance, and fatty liver disease. | 2011 | Details |
| A25683 | 21549113 | Eur J Pharmacol | Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease. | 2011 | Details |
| A25687 | 21543214 | J Nutr Biochem | Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver. | 2011 | Details |
| A25745 | 21488066 | Hepatology | Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. | 2011 | Details |
| A25781 | 21463337 | Alcohol Clin Exp Res | A new model of interactive effects of alcohol and high-fat diet on hepatic fibrosis. | 2011 | Details |
| A25798 | 21449029 | Biotechnol Bioeng | Use of three-dimensional spheroids of hepatocyte-derived reporter cells to study the effects of intracellular fat accumulation and subsequent cytokine exposure. | 2011 | Details |
| A25823 | 21425565 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Effect of xuezhlkang capsule in intervening different Chinese medical syndrome patterns of non-alcoholic fatty liver disease complicated with carotid atherosclerosis]. | 2011 | Details |