Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52092 | 31340878 | Proc Nutr Soc | Different physiological mechanisms underlie an adverse cardiovascular disease risk profile in men and women. | 2019 | Details |
| A52093 | 31311771 | DNA Repair (Amst) | Roles of OGG1 in transcriptional regulation and maintenance of metabolic homeostasis. | 2019 | Details |
| A52096 | 31307210 | FASEB J | Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes. | 2019 | Details |
| A52099 | 31275580 | BMJ Open Gastroenterol | Association of fatty liver disease with mortality outcomes in an Eastern Finland male cohort. | 2019 | Details |
| A52104 | 31184331 | Rev Invest Clin | NUTRIGENOMICS AS A TOOL IN THE PREVENTION OF LIPOTOXICITY: THE CASE OF SOY PROTEIN. | 2019 | Details |
| A52105 | 31141900 | Nutrients | Evaluating the Impact of Different Hypercaloric Diets on Weight Gain, Insulin Resistance, Glucose Intolerance, and its Comorbidities in Rats. | 2019 | Details |
| A52108 | 31113756 | Mol Metab | What role do fat cells play in pancreatic tissue? | 2019 | Details |
| A52109 | 31103416 | Biochem Pharmacol | Effects of Liraglutide and Fenretinide treatments on the diabetic phenotype of neuronal human BACE1 knock-in mice. | 2019 | Details |
| A52110 | 31091691 | Nutrients | Preventive Effects of the Marine Microalga Phaeodactylum tricornutum, Used as a Food Supplement, on Risk Factors Associated with Metabolic Syndrome in Wistar Rats. | 2019 | Details |
| A52111 | 31091179 | Viral Immunol | Hepatic Expression of Phosphorylated Kinase Akt and Glycogen Synthase Kinase-3 Isoforms in Patients with Chronic Hepatitis C. | 2019 | Details |
| A52115 | 31048842 | PLoS One | Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration. | 2019 | Details |
| A52120 | 30996248 | Nat Commun | Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. | 2019 | Details |
| A52121 | 30979946 | Sci Rep | Early impairments in the retina of rats fed with high fructose/high fat diet are associated with glucose metabolism deregulation but not dyslipidaemia. | 2019 | Details |
| A52124 | 30972920 | Physiol Rep | Resistance to visceral obesity is associated with increased locomotion in mice expressing an endothelial cell-specific fibroblast growth factor 1 transgene. | 2019 | Details |
| A52127 | 30944419 | Int J Obes (Lond) | Aryl hydrocarbon receptor agonist indigo protects against obesity-related insulin resistance through modulation of intestinal and metabolic tissue immunity. | 2019 | Details |
| A52128 | 30936147 | Diabetes | Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls. | 2019 | Details |
| A52129 | 30936145 | Diabetes | Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities. | 2019 | Details |
| A52130 | 30921498 | Mol Nutr Food Res | Dietary Palmitoleic Acid Attenuates Atherosclerosis Progression and Hyperlipidemia in Low-Density Lipoprotein Receptor-Deficient Mice. | 2019 | Details |
| A52132 | 30903919 | Biomed Pharmacother | Chinese medicine Jinlida granules improve high-fat-diet induced metabolic disorders via activation of brown adipose tissue in mice. | 2019 | Details |
| A52140 | 30796305 | Sci Rep | Reduced hepatocellular lipid accumulation and energy metabolism in patients with long standing type 1 diabetes mellitus. | 2019 | Details |
| A52142 | 30766812 | Indian J Endocrinol Metab | Evaluation of Proinflammatory Cytokines in Obese vs Non-obese Patients with Metabolic Syndrome. | 2022 | Details |
| A52144 | 30723473 | Front Immunol | Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice. | 2019 | Details |
| A52145 | 30694971 | Med Sci Sports Exerc | Physical Activity and Sedentary Time: Association with Metabolic Health and Liver Fat. | 2019 | Details |
| A52146 | 30689902 | J Clin Endocrinol Metab | Clinical Features of Nonobese, Apparently Healthy, Japanese Men With Reduced Adipose Tissue Insulin Sensitivity. | 2019 | Details |
| A52151 | 30649271 | Endocrinology | Adipocyte GR Inhibits Healthy Adipose Expansion Through Multiple Mechanisms in Cushing Syndrome. | 2019 | Details |
| A52152 | 30627105 | Front Physiol | Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus-A Co-expression Network Based Analysis. | 2018 | Details |
| A52153 | 30619718 | J Clin Transl Endocrinol | Metabolic effects of glucagon in humans. | 2018 | Details |
| A52156 | 30597839 | Medicines (Basel) | Chicken Protein Hydrolysates Have Anti-Inflammatory Effects on High-Fat Diet Induced Obesity in Mice. | 2018 | Details |
| A52158 | 30574122 | Front Endocrinol (Lausanne) | Sirtuins and Insulin Resistance. | 2018 | Details |
| A52161 | 30559212 | Proc Natl Acad Sci U S A | AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis. | 2018 | Details |
| A52162 | 30551378 | Biomed Pharmacother | A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models. | 2018 | Details |
| A52166 | 30481177 | PLoS One | A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone. | 2018 | Details |
| A52170 | 30464235 | Int J Obes (Lond) | Very low calorie diets are associated with transient ventricular impairment before reversal of diastolic dysfunction in obesity. | 2018 | Details |
| A52172 | 30429322 | Proc Natl Acad Sci U S A | Obesity-associated exosomal miRNAs modulate glucose and lipid metabolism in mice. | 2018 | Details |
| A52173 | 30425250 | Nat Commun | Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN. | 2018 | Details |
| A52174 | 30423963 | Nutrients | Ursolic Acid Attenuates Hepatic Steatosis, Fibrosis, and Insulin Resistance by Modulating the Circadian Rhythm Pathway in Diet-Induced Obese Mice. | 2018 | Details |
| A52176 | 30396212 | Exp Clin Endocrinol Diabetes | Impact of Brain Fatty Acid Signaling on Peripheral Insulin Action in Mice. | 2018 | Details |
| A52178 | 30379219 | Clinics (Sao Paulo) | α-Linolenic acid prevents hepatic steatosis and improves glucose tolerance in mice fed a high-fat diet. | 2018 | Details |
| A52181 | 30353455 | Eat Weight Disord | Ghrelin forms in the modulation of energy balance and metabolism. | 2018 | Details |
| A52182 | 30346829 | FASEB J | Normalizing adiponectin levels in obese pregnant mice prevents adverse metabolic outcomes in offspring. | 2018 | Details |
| A52185 | 30320914 | J Cell Biochem | Protein translation associated to PERK arm is a new target for regulation of metainflammation: A connection with hepatocyte cholesterol. | 2018 | Details |
| A52187 | 30308265 | Mol Cell Endocrinol | A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model. | 2018 | Details |
| A52188 | 30307158 | J Mol Endocrinol | The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases | 2018 | Details |
| A52190 | 30296183 | Curr Med Res Opin | Monogenic forms of lipodystrophic syndromes: diagnosis, detection, and practical management considerations from clinical cases. | 2018 | Details |
| A52192 | 30246767 | Infez Med | No effect of MTP polymorphisms on PNPLA3 in HCV-correlated steatosis. | 2018 | Details |
| A52195 | 30213825 | Diabetes | CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet. | 2018 | Details |
| A52196 | 30212233 | Chronobiol Int | Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice. | 2018 | Details |
| A52198 | 30201971 | Nat Commun | ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes. | 2018 | Details |
| A52200 | 30159588 | Diabetologia | Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study. | 2018 | Details |
| A52203 | 30138163 | Ann Surg | Exercise Improves Outcomes of Surgery on Fatty Liver in Mice: A Novel Effect Mediated by the AMPK Pathway. | 2020 | Details |
| A52208 | 30109419 | Eur J Nutr | Metabolic alterations associated with maternal undernutrition during the first half of gestation lead to a diabetogenic state in the rat. | 2018 | Details |
| A52210 | 30085057 | Endocrinology | Mouse Embryonic Fibroblasts Protect ob/ob Mice From Obesity and Metabolic Complications. | 2018 | Details |
| A52213 | 30049588 | Nutr Res | The interplay of canonical and noncanonical Wnt signaling in metabolic syndrome. | 2018 | Details |
| A52214 | 30040479 | Am J Physiol Endocrinol Metab | Differential contribution of chronic binge alcohol and antiretroviral therapy to metabolic dysregulation in SIV-infected male macaques. | 2018 | Details |
| A52215 | 30032428 | Diabetologia | A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes. | 2018 | Details |
| A52218 | 29998913 | J Atheroscler Thromb | Pathophysiology of Diabetic Dyslipidemia. | 2018 | Details |
| A52219 | 29980484 | Mol Metab | FGF21 regulates insulin sensitivity following long-term chronic stress. | 2018 | Details |
| A52220 | 29966982 | Biomed Pharmacother | Evidence of hypoglycemic, lipid-lowering and hepatoprotective effects of the Bixin and Bixin: β-CD inclusion compound in high-fat-fed obese mice. | 2018 | Details |
| A52222 | 29942089 | Nat Med | Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. | 2018 | Details |
| A52227 | 29908753 | Dig Liver Dis | Abdominal obesity and insulin resistance after an episode of acute pancreatitis. | 2018 | Details |
| A52228 | 29908359 | Clin Gastroenterol Hepatol | Statin Therapy Does Not Reduce Liver Fat Scores in Patients Receiving Antiretroviral Therapy for HIV Infection. | 2018 | Details |
| A52233 | 29895033 | Front Horm Res | Metabolic Syndrome in Hypopituitarism. | 2018 | Details |
| A52234 | 29886355 | Atherosclerosis | Ferritin, metabolic syndrome and its components: A systematic review and meta-analysis. | 2018 | Details |
| A52239 | 29812971 | FASEB J | Epigenetic programming at the Mogat1 locus may link neonatal overnutrition with long-term hepatic steatosis and insulin resistance. | 2018 | Details |
| A52240 | 29790245 | Diabetes Obes Metab | P465L-PPARγ mutation confers partial resistance to the hypolipidaemic action of fibrates. | 2018 | Details |
| A52241 | 29789270 | Mol Metab | Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic mice. | 2018 | Details |
| A52243 | 29768198 | Cell Rep | Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis. | 2018 | Details |
| A52246 | 29730627 | BMJ Open | Short-term abstinence from alcohol and changes in cardiovascular risk factors, liver function tests and cancer-related growth factors: a prospective observational study. | 2018 | Details |
| A52248 | 29689264 | Gastroenterology | Disruption of Epithelial HDAC3 in Intestine Prevents Diet-Induced Obesity in Mice. | 2018 | Details |
| A52251 | 29684438 | Exp Neurol | The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics. | 2018 | Details |
| A52252 | 29681858 | Front Pharmacol | Aqueous Extract of Black Maca Prevents Metabolism Disorder via Regulating the Glycolysis/Gluconeogenesis-TCA Cycle and PPARα Signaling Activation in Golden Hamsters Fed a High-Fat, High-Fructose Diet. | 2018 | Details |
| A52254 | 29659785 | Endocrinology | Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice. | 2018 | Details |
| A52259 | 29596053 | Horm Mol Biol Clin Investig | The "adipose tissue expandability" hypothesis: a potential mechanism for insulin resistance in obese youth. | 2018 | Details |
| A52262 | 29524177 | J Endocrinol Invest | Components of metabolic syndrome in relation to plasma levels of retinol binding protein 4 (RBP4) in a cohort of people aged 65 years and older. | 2018 | Details |
| A52267 | 29477938 | Curr Opin Genet Dev | Genetic syndromes of severe insulin resistance. | 2018 | Details |
| A52269 | 29453696 | Heart Fail Rev | Interrelationship between diabetes mellitus and heart failure: the role of peroxisome proliferator-activated receptors in left ventricle performance. | 2018 | Details |
| A52272 | 29419749 | Int J Mol Sci | Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr-/- Mice. | 2018 | Details |
| A52273 | 29406938 | Prim Care | Metabolic Syndrome: Systems Thinking in Heart Disease. | 2018 | Details |
| A52275 | 29402742 | Bioorg Med Chem Lett | Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice. | 2018 | Details |
| A52276 | 29398618 | Mol Metab | A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction. | 2018 | Details |
| A52279 | 29371333 | Eur J Endocrinol | MECHANISMS IN ENDOCRINOLOGY: SGLT2 inhibitors: clinical benefits by restoration of normal diurnal metabolism? | 2018 | Details |
| A52287 | 29115530 | Mol Med Rep | Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats. | 2017 | Details |
| A52289 | 29074588 | Arterioscler Thromb Vasc Biol | GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. | 2017 | Details |
| A52291 | 30581334 | J Med Biochem | The Monitoring of Protein Markers of Inflammation and Serum Lipid Concentration in Obese Subjects with Metabolic Syndrome. | 2017 | Details |
| A52292 | 29055921 | Ann Hepatol | Hepatitis C and Its Metabolic Complications in Kidney Disease. | 2018 | Details |
| A52296 | 28986283 | Biochim Biophys Acta Mol Cell Biol Lipids | Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice. | 2017 | Details |
| A52299 | 28940824 | Liver Int | Clinical implications of controlled attenuation parameter in a health check-up cohort. | 2017 | Details |
| A52301 | 28901330 | Int J Obes (Lond) | A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue. | 2017 | Details |
| A52303 | 28888048 | J Cell Physiol | Involvement of nutrients and nutritional mediators in mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene expression. | 2017 | Details |
| A52304 | 28867797 | Nutrients | Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway. | 2017 | Details |
| A52305 | 28839198 | Sci Rep | The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis. | 2017 | Details |
| A52307 | 28823009 | J Gastroenterol | Proton pump inhibitors as risk factor for metabolic syndrome and hepatic steatosis in coeliac disease patients on gluten-free diet. | 2017 | Details |
| A52308 | 28811612 | Sci Rep | Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition. | 2017 | Details |
| A52312 | 28800326 | J Alzheimers Dis | Intracerebroventricular Streptozotocin Induces Obesity and Dementia in Lewis Rats. | 2017 | Details |
| A52313 | 28778179 | Orphanet J Rare Dis | Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients? | 2017 | Details |
| A52316 | 28743670 | J Ethnopharmacol | Xuefu Zhuyu decoction ameliorates obesity, hepatic steatosis, neuroinflammation, amyloid deposition and cognition impairment in metabolically stressed APPswe/PS1dE9 mice. | 2017 | Details |
| A52317 | 28739173 | Biochim Biophys Acta Mol Basis Dis | Lipid droplet proteins and metabolic diseases. | 2017 | Details |
| A52319 | 28711626 | Gastroenterology | Influence of Metabolic Risk Factors on Risk of Hepatocellular Carcinoma and Liver-Related Death in Men With Chronic Hepatitis B: A Large Cohort Study. | 2017 | Details |
| A52321 | 28689096 | Eur J Med Chem | Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes. | 2017 | Details |
| A52322 | 28672736 | Horm Mol Biol Clin Investig | Innate immunity orchestrates adipose tissue homeostasis. | 2017 | Details |