Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A49353 | 35780715 | Growth Horm IGF Res | Expression of IGF-1 receptor and GH receptor in hepatic tissue of patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2022 | Details |
A49356 | 35779422 | Biomed Pharmacother | Recent advances in lean NAFLD. | 2022 | Details |
A49358 | 35779256 | J Clin Endocrinol Metab | The GH/IGF-1 axis is associated with intrahepatic lipid content and hepatocellular damage in overweight/obesity. | 2022 | Details |
A49366 | 35777449 | Biochem Pharmacol | Ceramide de novo synthesis in non-alcoholic fatty liver disease: Pathogenic mechanisms and therapeutic perspectives. | 2022 | Details |
A49368 | 35774609 | Front Pharmacol | Exploring Ganweikang Tablet as a Candidate Drug for NAFLD Through Network Pharmacology Analysis and Experimental Validation. | 2022 | Details |
A49369 | 35773644 | BMC Gastroenterol | Evaluating future risk of NAFLD in adolescents: a prediction and decision curve analysis. | 2022 | Details |
A49377 | 35769208 | Mediators Inflamm | MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice. | 2022 | Details |
A49390 | 35766414 | J Clin Endocrinol Metab | Fibrosis Risk in Nonalcoholic Fatty Liver Disease is Related to Chronic Kidney Disease in Aged Type 2 Diabetes Patients. | 2022 | Details |
A49392 | 35765700 | Hepatol Commun | Growth hormone deficiency and NAFLD: An overlooked and underrecognized link. | 2022 | Details |
A49396 | 35765026 | J Transl Med | Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome. | 2022 | Details |
A49407 | 35760372 | Diabetes Metab | Prevalence and predictors of non-alcoholic steatohepatitis in subjects with morbid obesity and with or without type 2 diabetes. | 2022 | Details |
A49409 | 35760093 | Life Sci | The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions. | 2022 | Details |
A49412 | 35758506 | J Pediatr Gastroenterol Nutr | Autoimmune Antibodies in Children and Adolescents with Nonalcoholic Fatty Liver Disease. | 2022 | Details |
A49417 | 35757404 | Front Endocrinol (Lausanne) | Hepatic Stellate Cell-Immune Interactions in NASH. | 2022 | Details |
A49421 | 35757147 | Int J Cardiol Heart Vasc | Synergistic effects of liver fibrosis and sarcopenia on endothelial dysfunction and arterial stiffness in patients with type 2 diabetes. | 2022 | Details |
A49422 | 35757117 | Front Pediatr | Prevalence and Risk Factors for Hepatic Steatosis in Children With Perinatal HIV on Early Antiretroviral Therapy Compared to HIV-Exposed Uninfected and HIV-Unexposed Children. | 2022 | Details |
A49432 | 35750138 | J Hepatol | Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH. | 2022 | Details |
A49433 | 35750137 | J Hepatol | Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits. | 2022 | Details |
A49434 | 35749236 | J Nat Prod | Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway. | 2022 | Details |
A49442 | 35748302 | J Gastroenterol Hepatol | Circulating adiponectin in patients with nonalcoholic fatty liver disease-related liver fibrosis: a systematic review and a meta-analysis. | 2022 | Details |
A49449 | 35745284 | Nutrients | Relation of Dietary Patterns and Nutritional Profile to Hepatic Fibrosis in a Sample of Lebanese Non-Alcoholic Fatty Liver Disease Patients. | 2022 | Details |
A49453 | 35745223 | Nutrients | Very Low Alcohol Consumption Is Associated with Lower Prevalence of Cirrhosis and Hepatocellular Carcinoma in Patients with Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
A49455 | 35745142 | Nutrients | Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice. | 2022 | Details |
A49461 | 35744805 | Molecules | Drugs Targeting the A3 Adenosine Receptor: Human Clinical Study Data. | 2022 | Details |
A49463 | 35744053 | Medicina (Kaunas) | Deuterium-Reinforced Polyunsaturated Fatty Acids Prevent Diet-Induced Nonalcoholic Steatohepatitis by Reducing Oxidative Stress. | 2022 | Details |
A49464 | 35744024 | Medicina (Kaunas) | An Update on the Chemokine System in the Development of NAFLD. | 2022 | Details |
A49469 | 35743358 | J Clin Med | When Sugar Reaches the Liver: Phenotypes of Patients with Diabetes and NAFLD. | 2022 | Details |
A49473 | 35743140 | Int J Mol Sci | Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis. | 2022 | Details |
A49477 | 35740949 | Biomolecules | NAFLD: Mechanisms, Treatments, and Biomarkers. | 2022 | Details |
A49479 | 35740337 | Biomedicines | Identification of the Potential Molecular Mechanisms Linking RUNX1 Activity with Nonalcoholic Fatty Liver Disease, by Means of Systems Biology. | 2022 | Details |
A49480 | 35740312 | Biomedicines | Hepatic Mitochondrial Dysfunction and Risk of Liver Disease in an Ovine Model of "PCOS Males". | 2022 | Details |
A49482 | 35740267 | Biomedicines | Combined Effects of Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease on the Risk of Cardiovascular Disease in Patients with Diabetes. | 2022 | Details |
A49492 | 35738255 | Semin Liver Dis | Intestinal Barrier Dysfunction in Fatty Liver Disease: Roles of Microbiota, Mucosal Immune System, and Bile Acids. | 2022 | Details |
A49496 | 35736460 | Metabolites | A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies. | 2022 | Details |
A49497 | 35736447 | Metabolites | Interactions between Tryptophan Metabolism, the Gut Microbiome and the Immune System as Potential Drivers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Diseases. | 2022 | Details |
A49501 | 35735003 | J Int Med Res | Combinational elastography for assessment of liver fibrosis in patients with liver injury. | 2022 | Details |
A49504 | 35733806 | Front Pediatr | Higher Levels of Plasma Hyaluronic Acid and N-terminal Propeptide of Type III Procollagen Are Associated With Lower Kidney Function in Children With Non-alcoholic Fatty Liver Disease. | 2022 | Details |
A49509 | 35731428 | Dig Dis Sci | Crohn's Disease Is Associated with Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. | 2022 | Details |
A49512 | 35730208 | Clin Mol Hepatol | Auranofin attenuates hepatic steatosis and fibrosis in non-alcoholic fatty liver disease via NRF2 and NF-κB signaling pathways. | 2022 | Details |
A49515 | 35728962 | Cas Lek Cesk | An overview of current therapy options of non-alcoholic fatty liver disease. | 2022 | Details |
A49523 | 35727151 | Radiology | Two-dimensional Shear-Wave Elastography and US Attenuation Imaging for Nonalcoholic Steatohepatitis Diagnosis: A Cross-sectional, Multicenter Study. | 2022 | Details |
A49526 | 35726536 | Eur J Histochem | Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2022 | Details |
A49527 | 35726152 | Endocrinol Metab (Seoul) | The Impact of Insulin Resistance on Hepatic Fibrosis among United States Adults with Non-Alcoholic Fatty Liver Disease: NHANES 2017 to 2018. | 2022 | Details |
A49528 | 35725929 | Genes Immun | The presence of interferon affects the progression of non-alcoholic fatty liver disease. | 2022 | Details |
A49536 | 35721884 | World J Gastroenterol | Gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid-enhanced magnetic resonance imaging for evaluating fibrosis regression in chronic hepatitis C patients after direct-acting antiviral. | 2022 | Details |
A49539 | 35721296 | World J Hepatol | Prognostic non-invasive biomarkers for all-cause mortality in non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2022 | Details |
A49543 | 35720958 | 3 Biotech | Amelioration of high-fat diet (HFD) + CCl4 induced NASH/NAFLD in CF-1 mice by activation of SIRT-1 using cinnamoyl sulfonamide hydroxamate derivatives: in-silico molecular modelling and in-vivo prediction. | 2022 | Details |
A49545 | 35720167 | World J Gastrointest Pathophysiol | Utility of FibroScan-based scoring systems to narrow the risk group of nonalcoholic fatty liver disease with comorbidities. | 2022 | Details |
A49546 | 35720113 | Front Mol Biosci | Ferroptosis in Chronic Liver Diseases: Opportunities and Challenges. | 2022 | Details |
A49551 | 35717907 | Biochem Biophys Res Commun | S100A9 promotes inflammatory response in diabetic nonalcoholic fatty liver disease. | 2022 | Details |
A49553 | 35716542 | Phytomedicine | Phillygenin ameliorates nonalcoholic fatty liver disease via TFEB-mediated lysosome biogenesis and lipophagy. | 2022 | Details |
A49556 | 35714879 | J Ethnopharmacol | Betulinic acid prevents liver fibrosis by binding Lck and suppressing Lck in HSC activation and proliferation. | 2022 | Details |
A49558 | 35714570 | Biochem Biophys Res Commun | TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells. | 2022 | Details |
A49560 | 35713854 | Obes Surg | Endoscopic Bariatric Treatment with Duodenal-Jejunal Bypass Liner Improves Non-invasive Markers of Non-alcoholic Steatohepatitis. | 2022 | Details |
A49561 | 35713614 | Lab Med | Association of rs5742612 Polymorphism in the Promoter Region of IGF1 Gene with Nonalcoholic Fatty Liver Disease: A Case-Control Study. | 2022 | Details |
A49564 | 35712786 | Hepatology | Circulating TREM2 as a non-invasive diagnostic biomarker for NASH in patients with elevated liver stiffness. | 2022 | Details |
A49571 | 35709934 | Clin Gastroenterol Hepatol | Incidence of Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. | 2022 | Details |
A49572 | 35709779 | Acta Gastroenterol Belg | Non-invasive screening, staging and management of metabolic dysfunction-associated fatty liver disease (MAFLD) in type 2 diabetes mellitus patients: what do we know so far ? | 2022 | Details |
A49575 | 35709466 | PLoS One | Prognostic impact of steatosis in the clinical course of chronic HCV infection-Results from the German Hepatitis C-Registry. | 2022 | Details |
A49578 | 35708088 | Curr Stem Cell Res Ther | Co-culture of liver parenchymal cells with non-parenchymal cells under 2D and 3D culture systems; a review paper. | 2022 | Details |
A49579 | 35708049 | Crit Rev Food Sci Nutr | Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review. | 2022 | Details |
A49586 | 35702844 | J Assoc Physicians India | A Study on FibroScan and Endoscopic Finding in Patients of Chronic Liver Disease attending Tripura Medical College and Dr. B.R. Ambedkar Memorial Teaching Hospital. | 2022 | Details |
A49587 | 35702836 | J Assoc Physicians India | Interrelation of the Risk Factors of NAFLD at various Stages of Progression of the glycemic Status on long-term Follow-up. | 2022 | Details |
A49589 | 35701716 | Hepatol Int | A new risk stratification strategy for fatty liver disease by incorporating MAFLD and fibrosis score in a large US population. | 2022 | Details |
A49591 | 35700738 | Cell Metab | MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH. | 2022 | Details |
A49592 | 35700593 | Nutrition | Short-term high-fat and high-carbohydrate diets increase susceptibility to liver injury by inducing hepatic procoagulant and proinflammatory conditions with different balances. | 2022 | Details |
A49593 | 35698652 | Diabetes Metab Syndr Obes | Fibrosis Predictive Score in Caucasian Patients with Metabolic Syndrome. | 2022 | Details |
A49594 | 35697996 | Obes Surg | The Benefit of Bariatric Surgery on Histological Features of Metabolic Associated Fatty Liver Disease Assessed Through Noninvasive Methods. | 2022 | Details |
A49599 | 35695040 | Expert Rev Mol Med | The potential role of FNDC5/irisin in various liver diseases: awakening the sleeping beauties. | 2022 | Details |
A49608 | 35693370 | Cureus | Comparing the Efficacy and Safety of Obeticholic Acid and Semaglutide in Patients With Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2022 | Details |
A49609 | 35692676 | J Clin Biochem Nutr | Pre-germinated brown rice alleviates non-alcoholic fatty liver disease induced by high fructose and high fat intake in rat. | 2022 | Details |
A49612 | 35692179 | Obes Rev | Evaluation of nonalcoholic fatty liver disease (NAFLD) in severe obesity using noninvasive tests and imaging techniques. | 2022 | Details |
A49613 | 35691383 | Environ Res | Association of blood manganese, selenium with steatosis, fibrosis in the National Health and Nutrition Examination Survey, 2017-18. | 2022 | Details |
A49617 | 35690264 | J Hepatol | Porto-sinusoidal vascular disorder. | 2022 | Details |
A49620 | 35689309 | Aliment Pharmacol Ther | Letter: non-invasive prediction models to exclude cirrhosis in NAFLD-not everyone fits the mould. Authors' reply. | 2022 | Details |
A49621 | 35689091 | Acta Pharmacol Sin | Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation. | 2022 | Details |
A49622 | 35688683 | Arab J Gastroenterol | Evaluation of hepatosteatosis in patients with chronic hepatitis B virus infection. | 2022 | Details |
A49623 | 35688322 | J Pharmacol Toxicol Methods | Establishment of a new nonalcoholic steatohepatitis model; Ovariectomy exacerbates nonalcoholic steatohepatitis-like pathology in diabetic rats. | 2022 | Details |
A49624 | 35688226 | J Hepatol | LIVER STIFFNESS, BUT NOT FATTY LIVER DISEASE, IS ASSOCIATED WITH ATRIAL FIBRILLATION: THE ROTTERDAM STUDY. | 2022 | Details |
A49632 | 35684158 | Nutrients | 11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway. | 2022 | Details |
A49634 | 35684079 | Nutrients | Consumption of Low Dose Fucoxanthin Does Not Prevent Hepatic and Adipose Inflammation and Fibrosis in Mouse Models of Diet-Induced Obesity. | 2022 | Details |
A49636 | 35683998 | Nutrients | Differential Effects of Dietary versus Exercise Intervention on Intrahepatic MAIT Cells and Histological Features of NAFLD. | 2022 | Details |
A49639 | 35683431 | J Clin Med | Triglyceride and Glucose Index as a Screening Tool for Nonalcoholic Liver Disease in Patients with Metabolic Syndrome. | 2022 | Details |
A49640 | 35682957 | Int J Mol Sci | Smad3 Phospho-Isoform Signaling in Nonalcoholic Steatohepatitis. | 2022 | Details |
A49649 | 35679904 | J Lipid Res | Inhibition of MAP4K4 Signaling Initiaties Metabolic Reprogramming to Protect Hepatocytes from Lipotoxic Damage. | 2022 | Details |
A49651 | 35678878 | Cell Mol Life Sci | The protective effect of selenoprotein M on non-alcoholic fatty liver disease: the role of the AMPKα1-MFN2 pathway and Parkin mitophagy. | 2022 | Details |
A49656 | 35677516 | J Clin Exp Hepatol | The Association Between Chronic Plaque Psoriasis and Nonalcoholic Fatty Liver Disease in Indian Patients: Results of a Pilot Study. | 2021 | Details |
A49660 | 35677506 | J Clin Exp Hepatol | Value of Liver Function Tests in Cirrhosis. | 2021 | Details |
A49664 | 35677306 | Front Bioeng Biotechnol | AgNPs Aggravated Hepatic Steatosis, Inflammation, Oxidative Stress, and Epigenetic Changes in Mice With NAFLD Induced by HFD. | 2022 | Details |
A49669 | 35675800 | Cell Metab | Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia. | 2022 | Details |
A49675 | 35673598 | J Hepatocell Carcinoma | Hepatocellular Carcinoma Due to Nonalcoholic Fatty Liver Disease: Current Concepts and Future Challenges. | 2022 | Details |
A49684 | 35671973 | Mol Metab | Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH. | 2022 | Details |
A49685 | 35671811 | Life Sci | Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades. | 2022 | Details |
A49687 | 35670949 | Obes Surg | Serum Ferritin and NAFLD in Patients Undergoing Bariatric Surgery. | 2022 | Details |
A49688 | 35670897 | Dig Dis Sci | Compensated Advanced Chronic Liver Disease in Nonalcoholic Fatty Liver Disease: Two-Step Strategy is Better than Baveno Criteria. | 2022 | Details |
A49691 | 35668917 | J Inflamm Res | Melatonin Suppresses NLRP3 Inflammasome Activation via TLR4/NF-κB and P2X7R Signaling in High-Fat Diet-Induced Murine NASH Model. | 2022 | Details |
A49697 | 35666557 | JMIR Med Inform | Noninvasive Diagnosis of Nonalcoholic Steatohepatitis and Advanced Liver Fibrosis Using Machine Learning Methods: Comparative Study With Existing Quantitative Risk Scores. | 2022 | Details |
A49699 | 35665350 | Front Med (Lausanne) | Association Between Monocyte to High-Density Lipoprotein Cholesterol Ratio and Risk of Non-alcoholic Fatty Liver Disease: A Cross-Sectional Study. | 2022 | Details |
A49701 | 35665109 | World J Clin Cases | Metabolic dysfunction is associated with steatosis but no other histologic features in nonalcoholic fatty liver disease. | 2022 | Details |
A49703 | 35664038 | World J Gastroenterol | Mechanisms of ductular reaction in non-alcoholic steatohepatitis. | 2022 | Details |