Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Calcium430 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00343 | 35127371 | Acta Pharm Sin B | Therapeutic regulation of autophagy in hepatic metabolism. | 2021 | Details |
| A00348 | 35126113 | Front Pharmacol | Fenofibrate Improves Insulin Resistance and Hepatic Steatosis and Regulates the Let-7/SERCA2b Axis in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Mice. | 2022 | Details |
| A00558 | 35047114 | World J Diabetes | Thioredoxin interacting protein, a key molecular switch between oxidative stress and sterile inflammation in cellular response. | 2021 | Details |
| A00671 | 35008682 | Int J Mol Sci | Emerging Roles of Calcium Signaling in the Development of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00698 | 34998993 | Clin Gastroenterol Hepatol | Association of Physical Activity With Risk of Liver Fibrosis, Sarcopenia, and Cardiovascular Disease in Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A00806 | 34959760 | Nutrients | Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study. | 2021 | Details |
| A00824 | 34956386 | Evid Based Complement Alternat Med | Procyanidin B2 Alleviates Palmitic Acid-Induced Injury in HepG2 Cells via Endoplasmic Reticulum Stress Pathway. | 2021 | Details |
| A01126 | 34862596 | Br J Pharmacol | Ruthenium 360 and mitoxantrone inhibit mitochondrial calcium uniporter channel to prevent liver steatosis induced by high-fat diet. | 2022 | Details |
| A01259 | 34811857 | Aging Cell | Cisd2 slows down liver aging and attenuates age-related metabolic dysfunction in male mice. | 2021 | Details |
| A01280 | 34803681 | Front Pharmacol | The Effects of Vitamin D Supplementation on Anthropometric and Biochemical Indices in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2021 | Details |
| A01307 | 34794237 | Biomed Pharmacother | Anti-inflammatory and anti-fibrotic effects of modafinil in nonalcoholic liver disease. | 2021 | Details |
| A01484 | 34729306 | Acta Pharm Sin B | 3D disorganization and rearrangement of genome provide insights into pathogenesis of NAFLD by integrated Hi-C, Nanopore, and RNA sequencing. | 2021 | Details |
| A01505 | 34718898 | Egypt Heart J | The associations between coronary artery disease, and non-alcoholic fatty liver disease by computed tomography. | 2021 | Details |
| A01519 | 34710938 | Z Gastroenterol | Non-alcoholic fatty liver disease (NAFLD) is associated with an increased incidence of osteoporosis and bone fractures. | 2021 | Details |
| A01546 | 34699301 | Adipocyte | Verapamil induces autophagy to improve liver regeneration in non-alcoholic fatty liver mice. | 2021 | Details |
| A01578 | 34686753 | Sci Rep | Clinically silent LINE 1 insertion in the PNPLA3 gene may impede genotyping of the p.I148M variant. | 2021 | Details |
| A01585 | 34684653 | Nutrients | Coffeeberry Activates the CaMKII/CREB/BDNF Pathway, Normalizes Autophagy and Apoptosis Signaling in Nonalcoholic Fatty Liver Rodent Model. | 2021 | Details |
| A01696 | 34651580 | J Clin Invest | Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2. | 2021 | Details |
| A01697 | 34651578 | J Clin Invest | Targeting adipose tissue to tackle NASH: SPARCL1 as an emerging player. | 2021 | Details |
| A01863 | 34584580 | Prz Gastroenterol | Association of non-alcoholic fatty liver disease with coronary artery calcification progression: a systematic review and meta-analysis. | 2021 | Details |
| A01936 | 34558838 | Hepatol Commun | Dietary Risks for Liver Mortality in NAFLD: Global Burden of Disease Data. | 2021 | Details |
| A01995 | 34535985 | Hepatol Commun | Genome-Wide Association Study of NAFLD Using Electronic Health Records. | 2021 | Details |
| A02103 | 34506332 | Clin Transl Gastroenterol | The Protection Conferred by HSD17B13 rs72613567 Polymorphism on Risk of Steatohepatitis and Fibrosis May Be Limited to Selected Subgroups of Patients With NAFLD. | 2021 | Details |
| A02155 | 34484304 | Front Genet | Genetic Polymorphism of Vitamin D Family Genes CYP2R1, CYP24A1, and CYP27B1 Are Associated With a High Risk of Non-alcoholic Fatty Liver Disease: A Case-Control Study. | 2021 | Details |
| A02158 | 34482352 | AIDS | Single nucleotide polymorphisms in PNPLA3, ADAR-1 and IFIH1 are associated with advanced liver fibrosis in patients co-infected with HIV-1//hepatitis C virus. | 2021 | Details |
| A02208 | 34459959 | Eur J Pediatr | Vitamin D and nonalcoholic fatty liver disease in children: a randomized controlled clinical trial. | 2021 | Details |
| A02269 | 34441013 | Medicina (Kaunas) | Association between the Severity of Nonalcoholic Fatty Liver Disease and the Risk of Coronary Artery Calcification. | 2021 | Details |
| A02329 | 34416350 | Toxicology | Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. | 2021 | Details |
| A02650 | 34297902 | Nucleic Acid Ther | Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02661 | 34294580 | Dig Liver Dis | Distinctive features of hepatocellular carcinoma in non-alcoholic fatty liver disease. | 2021 | Details |
| A02749 | 34261618 | Dig Liver Dis | PNPLA3 is the dominant SNP linked to liver disease severity at time of first referral to a tertiary center. | 2021 | Details |
| A02826 | 34228977 | Biochimie | Citrin deficiency: Does the reactivation of liver aralar-1 come into play and promote HCC development? | 2021 | Details |
| A02981 | 34174520 | Nutr Res | Bile acids induced hepatic lipid accumulation in mice by inhibiting mRNA expression of patatin-like phospholipase domain containing 3 and microsomal triglyceride transfer protein. | 2021 | Details |
| A03116 | 34124059 | Front Cell Dev Biol | Pathological Crosstalk Between Oxidized LDL and ER Stress in Human Diseases: A Comprehensive Review. | 2021 | Details |
| A03163 | 34106786 | Am J Physiol Cell Physiol | Impaired Ca2+ signaling due to hepatic steatosis mediates hepatic insulin resistance in Alström syndrome mice that is reversed by GLP-1 analog treatment. | 2021 | Details |
| A03267 | 34065270 | Nutrients | Comparison of the Improvement Effect of Deep Ocean Water with Different Mineral Composition on the High Fat Diet-Induced Blood Lipid and Nonalcoholic Fatty Liver Disease in a Mouse Model. | 2021 | Details |
| A03492 | 33984335 | Metabolism | Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy. | 2021 | Details |
| A03596 | 33938135 | Liver Int | Effects of lifestyle interventions on epigenetic signatures of liver fat: Central randomized controlled trial. | 2021 | Details |
| A03713 | 33895138 | J Biol Chem | Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background. | 2021 | Details |
| A03786 | 33864571 | Mol Cell Biochem | Upregulated SOCC and IP3R calcium channels and subsequent elevated cytoplasmic calcium signaling promote nonalcoholic fatty liver disease by inhibiting autophagy. | 2021 | Details |
| A03870 | 33838230 | J Nutr Biochem | Calcium supplementation relieves high-fat diet-induced liver steatosis by reducing energy metabolism and promoting lipolysis. | 2021 | Details |
| A03916 | 33818707 | Jpn J Radiol | The correlation between hepatic fat fraction evaluated by dual-energy computed tomography and high-risk coronary plaques in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A03979 | 33803038 | Int J Mol Sci | O-1602 Promotes Hepatic Steatosis through GPR55 and PI3 Kinase/Akt/SREBP-1c Signaling in Mice. | 2021 | Details |
| A04088 | 33764550 | Aliment Pharmacol Ther | Liver stiffness by magnetic resonance elastography is associated with increased risk of cardiovascular disease in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A04113 | 33752262 | FEBS Lett | Calcium transfer between endoplasmic reticulum and mitochondria in liver diseases. | 2021 | Details |
| A04156 | 33736626 | BMC Endocr Disord | Calcium to magnesium intake ratio and non-alcoholic fatty liver disease development: a case-control study. | 2021 | Details |
| A04162 | 33732887 | JGH Open | Coronary artery disease and non-alcoholic fatty liver disease: Clinical correlation using computed tomography coronary calcium scans. | 2021 | Details |
| A04515 | 33591626 | J Cell Mol Med | Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity. | 2021 | Details |
| A04518 | 33590347 | J Nat Med | Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis. | 2021 | Details |
| A04545 | 33583934 | J Epidemiol | Association between nutrient patterns and fatty liver index: Baseline survey of the Japan Multi-Institutional Collaborative Cohort Study in Tokushima, Japan. | 2021 | Details |
| A04554 | 33581332 | Mitochondrion | Mitochondrial metabolism and calcium homeostasis in the development of NAFLD leading to hepatocellular carcinoma. | 2021 | Details |
| A04591 | 33571540 | Metabolism | The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling. | 2021 | Details |
| A04756 | 33514365 | Cardiovasc Diabetol | Metabolic syndrome, fatty liver, and artificial intelligence-based epicardial adipose tissue measures predict long-term risk of cardiac events: a prospective study. | 2021 | Details |
| A04798 | 33503814 | Int J Mol Sci | Mediators of Metabolism: An Unconventional Role for NOD1 and NOD2. | 2021 | Details |
| A04925 | 33446707 | Sci Rep | The potential ameliorative impacts of cerium oxide nanoparticles against fipronil-induced hepatic steatosis. | 2021 | Details |
| A05007 | 33413363 | Cardiovasc Diabetol | Prognostic value of non-alcoholic fatty liver disease for predicting cardiovascular events in patients with diabetes mellitus with suspected coronary artery disease: a prospective cohort study. | 2021 | Details |
| A05030 | 33401717 | Int J Mol Sci | Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. | 2021 | Details |
| A05190 | 33341674 | Biochem Biophys Res Commun | Hepatocyte-specific TAZ deletion downregulates p62/ Sqstm1 expression in nonalcoholic steatohepatitis. | 2020 | Details |
| A05250 | 33324345 | Front Endocrinol (Lausanne) | Repression of MicroRNA-124-3p Alleviates High-Fat Diet-Induced Hepatosteatosis by Targeting Pref-1. | 2020 | Details |
| A05303 | 33308192 | BMC Complement Med Ther | Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-δ. | 2020 | Details |
| A05407 | 33269017 | J Med Biochem | Pentoxifylline with metformin treatment improves biochemical parameters in patients with nonalcoholic steatohepatitis. | 2020 | Details |
| A05516 | 33220425 | Free Radic Biol Med | Physiological evidence of mitochondrial permeability transition pore opening caused by lipid deposition leading to hepatic steatosis in db/db mice. | 2020 | Details |
| A05921 | 33075563 | Cell Mol Gastroenterol Hepatol | S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis. | 2020 | Details |
| A05956 | 33061886 | Food Nutr Res | Cross-sectional analysis of the health profile and dietary intake of a sample of Canadian adults diagnosed with non-alcoholic fatty liver disease. | 2020 | Details |
| A05967 | 33059580 | Curr Vasc Pharmacol | Prevalence, Diagnosis, and Treatment with 3 Different Statins of Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis in Military Personnel. Do Genetics Play a Role? | 2021 | Details |
| A06024 | 33036387 | Cells | Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings. | 2020 | Details |
| A06170 | 32980687 | Cytokine | CAT1 silencing inhibits TGF-β1-induced mouse hepatic stellate cell activation in vitro and hepatic fibrosis in vivo. | 2020 | Details |
| A06180 | 32978261 | J Biol Chem | ERAD deficiency promotes mitochondrial dysfunction and transcriptional rewiring in human hepatic cells. | 2020 | Details |
| A06239 | 32957701 | Biomolecules | Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver. | 2020 | Details |
| A06258 | 32951410 | Clin Mol Hepatol | Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases. | 2020 | Details |
| A06492 | 32856322 | J Pharm Pharmacol | Therapeutic effects of açaí seed extract on hepatic steatosis in high-fat diet-induced obesity in male mice: a comparative effect with rosuvastatin. | 2020 | Details |
| A06625 | 32802885 | Biomed Res Int | Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice. | 2020 | Details |
| A06633 | 32800550 | Biochem Biophys Res Commun | Metformin, resveratrol, and exendin-4 inhibit high phosphate-induced vascular calcification via AMPK-RANKL signaling. | 2020 | Details |
| A06746 | 32762728 | BMC Pharmacol Toxicol | Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease. | 2020 | Details |
| A06755 | 32759166 | BMJ Open Diabetes Res Care | Association between non-alcoholic fatty liver disease-associated hepatic fibrosis and bone mineral density in postmenopausal women with type 2 diabetes or impaired glucose regulation. | 2020 | Details |
| A06832 | 32730863 | Toxicol In Vitro | Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach. | 2020 | Details |
| A06919 | 32698042 | Cell Mol Gastroenterol Hepatol | Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes. | 2020 | Details |
| A07223 | 32576050 | Gut Microbes | Sex-specific maternal calcium requirements for the prevention of nonalcoholic fatty liver disease by altering the intestinal microbiota and lipid metabolism in the high-fat-diet-fed offspring mice. | 2020 | Details |
| A07286 | 32554851 | Aging (Albany NY) | CTRP13 attenuates the expression of LN and CAV-1 Induced by high glucose via CaMKKβ/AMPK pathway in rLSECs. | 2020 | Details |
| A07631 | 32414691 | J Pharmacol Sci | Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet. | 2020 | Details |
| A07669 | 32401929 | Braz J Med Biol Res | A Brazilian regional basic diet-induced chronic malnutrition drives liver inflammation with higher ApoA-I activity in C57BL6J mice. | 2020 | Details |
| A07875 | 32326590 | Int J Mol Sci | Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson's Disease. | 2020 | Details |
| A07996 | 32284046 | Lipids Health Dis | Mutual interaction between endoplasmic reticulum and mitochondria in nonalcoholic fatty liver disease. | 2020 | Details |
| A08063 | 32259482 | Cell Metab | Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. | 2020 | Details |
| A08270 | 32176760 | J Gastrointestin Liver Dis | Nonalcoholic Fatty Liver Disease as a Risk Factor for Prolonged Corrected QT Interval in Apparently Healthy Korean Women. | 2020 | Details |
| A08277 | 32171275 | BMC Pediatr | Analysis of the dietary factors associated with suspected pediatric nonalcoholic fatty liver disease and potential liver fibrosis: Korean National Health and Nutrition Examination Survey 2014-2017. | 2020 | Details |
| A08435 | 32111021 | Diagnostics (Basel) | Coronary Artery Disease is More Severe in Patients with Non-Alcoholic Steatohepatitis than Fatty Liver. | 2020 | Details |
| A08483 | 32092316 | Clin Chim Acta | Bnip3 in mitophagy: Novel insights and potential therapeutic target for diseases of secondary mitochondrial dysfunction. | 2020 | Details |
| A08788 | 31984787 | Am J Physiol Gastrointest Liver Physiol | Vitamin D signaling maintains intestinal innate immunity and gut microbiota: potential intervention for metabolic syndrome and NAFLD. | 2020 | Details |
| A08858 | 31960587 | Liver Int | The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease. | 2020 | Details |
| A08908 | 31941974 | Sci Rep | Polycystin 2 is increased in disease to protect against stress-induced cell death. | 2020 | Details |
| A09006 | 31907123 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Intervention of Catalpol on High-fat Diet Induced Nonalcoholic Fatty Liver Disease in Mice]. | 2019 | Details |
| A09059 | 33762794 | Toxicol Environ Chem | Perfluorobutanesulfonic Acid (PFBS) Induces Fat Accumulation in HepG2 Human Hepatoma. | 2020 | Details |
| A09087 | 31881201 | Exp Mol Pathol | Alpha-syntrophin deficiency protects against non-alcoholic steatohepatitis associated increase of macrophages, CD8+ T-cells and galectin-3 in the liver. | 2019 | Details |
| A09143 | 31860081 | Biosci Rep | Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A09741 | 31630405 | Clin Pharmacol Ther | Quantitative Proteomics and Mechanistic Modeling of Transporter-Mediated Disposition in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09766 | 31618976 | Int J Mol Sci | The Potential of the FSP1cre-Pparb/d-/- Mouse Model for Studying Juvenile NAFLD. | 2019 | Details |
| A09900 | 31568762 | Exp Cell Res | Involvement of sarco/endoplasmic reticulum calcium ATPase-mediated calcium flux in the protective effect of oleic acid against lipotoxicity in hepatocytes. | 2019 | Details |
| A10002 | 31529722 | Hepatology | Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice. | 2020 | Details |
| A10023 | 31521175 | Lipids Health Dis | Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities. | 2019 | Details |