Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Quercetin115 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00261 | 35162967 | Int J Mol Sci | Quercetin Reduces Lipid Accumulation in a Cell Model of NAFLD by Inhibiting De Novo Fatty Acid Synthesis through the Acetyl-CoA Carboxylase 1/AMPK/PP2A Axis. | 2022 | Details |
| A00624 | 35024184 | J Adv Res | Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism. | 2021 | Details |
| A00869 | 34944525 | Biomolecules | A System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach. | 2021 | Details |
| A00881 | 34943104 | Antioxidants (Basel) | The Synbiotic Combination of Akkermansia muciniphila and Quercetin Ameliorates Early Obesity and NAFLD through Gut Microbiota Reshaping and Bile Acid Metabolism Modulation. | 2021 | Details |
| A01027 | 34899351 | Front Pharmacol | Network Pharmacology-Based Analysis of Pogostemon cablin (Blanco) Benth Beneficial Effects to Alleviate Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A01233 | 34819792 | Saudi Pharm J | Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease. | 2021 | Details |
| A01262 | 34810376 | Saudi J Gastroenterol | Nonalcoholic fatty liver disease: The role of quercetin and its therapeutic implications. | 2022 | Details |
| A01317 | 34789244 | Lipids Health Dis | Protective effect of quercetin against the metabolic dysfunction of glucose and lipids and its associated learning and memory impairments in NAFLD rats. | 2021 | Details |
| A01704 | 34649337 | Biomed Pharmacother | Jiangzhi Granule attenuates non-alcoholic steatohepatitis by suppressing TNF/NFκB signaling pathway-a study based on network pharmacology. | 2021 | Details |
| A02254 | 34445644 | Int J Mol Sci | Resveratrol and Quercetin as Regulators of Inflammatory and Purinergic Receptors to Attenuate Liver Damage Associated to Metabolic Syndrome. | 2021 | Details |
| A02313 | 34423182 | ACS Omega | Effect of Silymarin and Quercetin in a Miniaturized Scaffold in Wistar Rats against Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A02474 | 34360538 | Int J Mol Sci | Diabetes Mellitus and Cardiovascular Diseases: Nutraceutical Interventions Related to Caloric Restriction. | 2021 | Details |
| A02556 | 34329714 | J Ethnopharmacol | Pharmacokinetic herb-disease-drug interactions: Effect of ginkgo biloba extract on the pharmacokinetics of pitavastatin, a substrate of Oatp1b2, in rats with non-alcoholic fatty liver disease. | 2021 | Details |
| A02568 | 34326886 | Evid Based Complement Alternat Med | Pharmacological Mechanisms Underlying the Hepatoprotective Effects of Ecliptae herba on Hepatocellular Carcinoma. | 2021 | Details |
| A02756 | 34257817 | Oxid Med Cell Longev | The Therapeutic Effects and Mechanisms of Quercetin on Metabolic Diseases: Pharmacological Data and Clinical Evidence. | 2021 | Details |
| A02859 | 34214346 | J Basic Clin Physiol Pharmacol | The effects of quercetin on the expression of SREBP-1c mRNA in high-fat diet-induced NAFLD in mice. | 2021 | Details |
| A03214 | 34087406 | Food Chem Toxicol | Quercetin and non-alcoholic fatty liver disease: A review based on experimental data and bioinformatic analysis. | 2021 | Details |
| A03447 | 33995543 | Evid Based Complement Alternat Med | Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03460 | 33992930 | Eur J Med Chem | Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview. | 2021 | Details |
| A03796 | 33861449 | Adv Exp Med Biol | Beneficial Effects of Plant-Derived Natural Products on Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A03889 | 33832488 | Cell Commun Signal | Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin. | 2021 | Details |
| A04160 | 33733575 | Biofactors | Quercetin prevents cadmium chloride-induced hepatic steatosis and fibrosis by downregulating the transcription of miR-21. | 2021 | Details |
| A04451 | 33611063 | Int Immunopharmacol | Hyperoside attenuates non-alcoholic fatty liver disease through targeting Nr4A1 in macrophages. | 2021 | Details |
| A04454 | 33609576 | Int J Biol Macromol | Synthesis of a green bigel using cottonseed oil/cannabis oil/alginate/ferula gum for quercetin release: Synergistic effects for treating infertility in rats. | 2021 | Details |
| A04513 | 33592427 | Clin Res Hepatol Gastroenterol | Integrated expression profiles of mRNA and miRNA in a gerbil model of fatty liver fibrosis treated with exenatide. | 2021 | Details |
| A05104 | 33374984 | Molecules | Honeybee Pollen Extracts Reduce Oxidative Stress and Steatosis in Hepatic Cells. | 2020 | Details |
| A05246 | 33325949 | Food Funct | Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis. | 2020 | Details |
| A05317 | 33303988 | Acta Pharmacol Sin | 3,4-dihydroxytoluene, a metabolite of rutin, suppresses the progression of nonalcoholic fatty liver disease in mice by inhibiting p300 histone acetyltransferase activity. | 2020 | Details |
| A05695 | 33152943 | Biomed Pharmacother | The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling. | 2020 | Details |
| A05773 | 33125573 | Mikrochim Acta | Immobilization of cell membrane onto a glucose-Zn-based porous coordination polymer and its application to rapid screening of potentially active compounds from Vaccinium corymbosum L. leaves. | 2020 | Details |
| A06285 | 32941865 | Biochem Pharmacol | Aryl hydrocarbon receptor (AHR)-mediated inflammation and resolution: Non-genomic and genomic signaling. | 2020 | Details |
| A06410 | 32889748 | Biotechnol Bioeng | Quercetin and hydroxytyrosol as modulators of hepatic steatosis: A NAFLD-on-a-chip study. | 2020 | Details |
| A06617 | 32807146 | BMC Complement Med Ther | Regulation effects of total flavonoids in Morus alba L. on hepatic cholesterol disorders in orotic acid induced NAFLD rats. | 2020 | Details |
| A06668 | 32786869 | J Agric Food Chem | Combined Effect of Quercetin and Fish Oil on Oxidative Stress in the Liver of Mice Fed a Western-Style Diet. | 2020 | Details |
| A07190 | 32588069 | Naunyn Schmiedebergs Arch Pharmacol | In vitro targeted screening and molecular docking of stilbene, quinones, and flavonoid on 3T3-L1 pre-adipocytes for anti-adipogenic actions. | 2020 | Details |
| A08246 | 32189432 | J Cell Mol Med | A network pharmacology-based approach to explore the effects of Chaihu Shugan powder on a non-alcoholic fatty liver rat model through nuclear receptors. | 2020 | Details |
| A08286 | 32169417 | Biochem Pharmacol | Modulation of aryl hydrocarbon receptor (AHR) and the NAD+-consuming enzyme CD38: Searches of therapeutic options for nonalcoholic fatty liver disease (NAFLD). | 2020 | Details |
| A08476 | 32095444 | Clin Nutr Res | Effects of Quercetin Supplementation on Hematological Parameters in Non-Alcoholic Fatty Liver Disease: a Randomized, Double-Blind, Placebo-Controlled Pilot Study. | 2020 | Details |
| A08595 | 32045667 | Pharmacol Res | Human antigen R: A potential therapeutic target for liver diseases. | 2020 | Details |
| A09364 | 31777425 | J Clin Biochem Nutr | Plasma quercetin metabolites are affected by intestinal microbiota of human microbiota-associated mice fed with a quercetin-containing diet. | 2019 | Details |
| A09545 | 31700054 | Sci Rep | Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis. | 2019 | Details |
| A10175 | 31452288 | Phytother Res | Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice. | 2019 | Details |
| A10243 | 31414497 | J Sci Food Agric | Quercetin administration post-weaning attenuates high-fructose, high-cholesterol diet-induced hepatic steatosis in growing, female, Sprague Dawley rat pups. | 2019 | Details |
| A10473 | 31322321 | Mol Nutr Food Res | A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A11516 | 30862046 | Int J Mol Sci | Metabolomics Characterizes the Effects and Mechanisms of Quercetin in Nonalcoholic Fatty Liver Disease Development. | 2019 | Details |
| A11580 | 30832407 | Nutrients | Dietary Polyphenols Protect Against Oleic Acid-Induced Steatosis in an in Vitro Model of NAFLD by Modulating Lipid Metabolism and Improving Mitochondrial Function. | 2019 | Details |
| A11759 | 30763486 | Vopr Pitan | [Effect of quercetin on morphological changes in nonalcoholic fatty liver disease in high fructose-fed rats]. | 2018 | Details |
| A11922 | 30680920 | Mol Nutr Food Res | Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High-Fat Diet Determine Non-Alcoholic Fatty Liver Disease Development in Germ-Free Mice. | 2019 | Details |
| A12183 | 30572631 | Int J Mol Sci | Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model. | 2018 | Details |
| A12490 | 30425964 | Front Oncol | Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer. | 2018 | Details |
| A12759 | 30298849 | J Toxicol Sci | Differential impacts of mineralocorticoid receptor antagonist potassium canrenoate on liver and renal changes in high fat diet-mediated early hepatocarcinogenesis model rats. | 2018 | Details |
| A12973 | 30201876 | Nutrients | Preventive Effect of Flavonol Derivatives Abundant Sanglan Tea on Long-Term High-Fat-Diet-Induced Obesity Complications in C57BL/6 Mice. | 2018 | Details |
| A13048 | 30165848 | BMC Complement Altern Med | Comparison of the main components and bioactivity of Rhus verniciflua Stokes extracts by different detoxification processing methods. | 2018 | Details |
| A13107 | 30135414 | Molecules | Modulatory Effect of Polyphenolic Compounds from the Mangrove Tree Rhizophora mangle L. on Non-Alcoholic Fatty Liver Disease and Insulin Resistance in High-Fat Diet Obese Mice. | 2018 | Details |
| A13445 | 29970566 | Anticancer Res | Global Liver Gene Expression Analysis on a Murine Hepatic Steatosis Model Treated with Mulberry (Morus alba L.) Leaf Powder. | 2018 | Details |
| A13520 | 29935106 | Mol Nutr Food Res | Frataxin-Mediated PINK1-Parkin-Dependent Mitophagy in Hepatic Steatosis: The Protective Effects of Quercetin. | 2018 | Details |
| A13988 | 29655752 | Food Chem | Systematic evaluation of phenolic compounds and protective capacity of a new mulberry cultivar J33 against palmitic acid-induced lipotoxicity using a simulated digestion method. | 2018 | Details |
| A14319 | 29469041 | Ann Hepatol | Natural Extracts Abolished Lipid Accumulation in Cells Harbouring non-favourable PNPLA3 genotype. | 2018 | Details |
| A14375 | 29438776 | Food Chem Toxicol | Quercetin ameliorates HFD-induced NAFLD by promoting hepatic VLDL assembly and lipophagy via the IRE1a/XBP1s pathway. | 2018 | Details |
| A14474 | 29396908 | Mol Nutr Food Res | Mice Fed a High-Cholesterol Diet Supplemented with Quercetin-3-Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas. | 2018 | Details |
| A14500 | 29379801 | J Diabetes Res | Quercetin Improves Glucose and Lipid Metabolism of Diabetic Rats: Involvement of Akt Signaling and SIRT1. | 2017 | Details |
| A14731 | 29268106 | J Nutr Biochem | Food components with antifibrotic activity and implications in prevention of liver disease. | 2017 | Details |
| A15231 | 29034200 | J Tradit Complement Med | Promising effect of Rosa damascena extract on high-fat diet-induced nonalcoholic fatty liver. | 2017 | Details |
| A15819 | 28694655 | World J Gastroenterol | Antioxidant dietary approach in treatment of fatty liver: New insights and updates. | 2017 | Details |
| A15897 | 28664744 | Bratisl Lek Listy | Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage. | 2017 | Details |
| A16002 | 28618991 | Curr Med Chem | Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions. | 2018 | Details |
| A16018 | 28608850 | Nat Commun | Cellular senescence drives age-dependent hepatic steatosis. | 2017 | Details |
| A16560 | 28317281 | Mol Nutr Food Res | Comparison of dietary polyphenols for protection against molecular mechanisms underlying nonalcoholic fatty liver disease in a cell model of steatosis. | 2017 | Details |
| A17143 | 27959936 | PLoS One | A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. | 2016 | Details |
| A17246 | 27890642 | Free Radic Biol Med | Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation. | 2016 | Details |
| A18300 | 27228698 | Vopr Pitan | [The study of biochemical mechanisms of mitochondrial dysfunction in rats' hepatocytes during experimental hyperhomocysteinemia]. | 2016 | Details |
| A19078 | 26775807 | Sci Rep | Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiency. | 2016 | Details |
| A19219 | 26697490 | Biomed Res Int | Quercetin Alleviates High-Fat Diet-Induced Oxidized Low-Density Lipoprotein Accumulation in the Liver: Implication for Autophagy Regulation. | 2015 | Details |
| A19457 | 26557974 | Iran J Basic Med Sci | Effect of pioglitazone, quercetin and hydroxy citric acid on extracellular matrix components in experimentally induced non-alcoholic steatohepatitis. | 2015 | Details |
| A19635 | 26445592 | Nutr Metab (Lond) | Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1. | 2015 | Details |
| A19891 | 26281317 | Turk J Med Sci | Effect of pioglitazone, quercetin, and hydroxy citric acid on vascular endothelial growth factor messenger RNA (VEGF mRNA) expression in experimentally induced nonalcoholic steatohepatitis (NASH). | 2015 | Details |
| A19981 | 26228038 | Lipids Health Dis | Effect of a high fat, high sucrose diet on the promotion of non-alcoholic fatty liver disease in male rats: the ameliorative role of three natural compounds. | 2015 | Details |
| A20053 | 26190035 | Hepatol Res | Amelioration of free fatty acid-induced fatty liver by quercetin-3-O-β-D-glucuronide through modulation of peroxisome proliferator-activated receptor-alpha/sterol regulatory element-binding protein-1c signaling. | 2015 | Details |
| A20654 | 25829790 | Pharmacognosy Res | Psidium guajava Linn. leaf extract affects hepatic glucose transporter-2 to attenuate early onset of insulin resistance consequent to high fructose intake: An experimental study. | 2015 | Details |
| A20655 | 25827944 | J Physiol Biochem | Liver delipidating effect of a combination of resveratrol and quercetin in rats fed an obesogenic diet. | 2015 | Details |
| A20822 | 25712622 | Mol Nutr Food Res | Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease. | 2015 | Details |
| A20985 | 25602171 | Antioxid Redox Signal | Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation. | 2015 | Details |
| A21064 | 27453880 | J Diabetes Metab Disord | The effects of onion consumption on treatment of metabolic, histologic, and inflammatory features of nonalcoholic fatty liver disease. | 2016 | Details |
| A21258 | 25451038 | Obesity (Silver Spring) | A dietary phytochemical blend prevents liver damage associated with adipose tissue mobilization in ovariectomized rats. | 2014 | Details |
| A21440 | 25317811 | Eur Rev Med Pharmacol Sci | Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). | 2014 | Details |
| A21619 | 25183267 | J Biomed Sci | Flavonoid ingredients of Ginkgo biloba leaf extract regulate lipid metabolism through Sp1-mediated carnitine palmitoyltranferase 1A up-regulation. | 2014 | Details |
| A21913 | 24966607 | World J Gastroenterol | Effects of resveratrol and other polyphenols in hepatic steatosis. | 2014 | Details |
| A22184 | 24761121 | Pharmacognosy Res | Pioglitazone, quercetin and hydroxy citric acid effect on hepatic biomarkers in Non Alcoholic Steatohepatitis. | 2014 | Details |
| A22233 | 24735863 | J Ethnopharmacol | Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARα pathways in L02 cells and HepG2 cells. | 2014 | Details |
| A22393 | 24622831 | J Physiol Pharmacol | Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. | 2014 | Details |
| A23573 | 23663887 | Zhonghua Gan Zang Bing Za Zhi | [Therapeutic efficacy and mechanisms of quercetin in a rat model of nonalcoholic fatty liver disease]. | 2013 | Details |
| A23574 | 23663767 | Zhonghua Gan Zang Bing Za Zhi | [Effects of quercetin on serum levels of resistin and IL-18 and on insulin resistance in nonalcoholic fatty liver disease rats]. | 2013 | Details |
| A23596 | 23647015 | Br J Pharmacol | Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. | 2013 | Details |
| A23962 | 23348005 | Toxicol In Vitro | Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells. | 2013 | Details |
| A23976 | 23331460 | Basic Clin Pharmacol Toxicol | Quercetin decreases liver damage in mice with non-alcoholic steatohepatitis. | 2013 | Details |
| A24066 | 24648896 | Biomed Rep | Quercetin improves insulin resistance and hepatic lipid accumulation in vitro in a NAFLD cell model. | 2012 | Details |
| A24207 | 23123425 | Food Chem Toxicol | Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils. | 2012 | Details |
| A24335 | 22988926 | J Dig Dis | Inhibitory effect of Ginkgo biloba extract on fatty liver: regulation of carnitine palmitoyltransferase 1a and fatty acid metabolism. | 2012 | Details |
| A24420 | 22915297 | J Nutr | Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis. | 2012 | Details |
| A24753 | 22535755 | J Nutr | Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats. | 2012 | Details |