Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Cardiovascular137 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R1281 | DB09282 | approved; investigational | small molecule | Molsidomine | Therapeutic strategy associated | Details |
| R1288 | DB09292 | approved | small molecule | Sacubitril | Indication associated | Details |
| R1291 | DB09302 | approved | biotech | Alirocumab | Indication associated | Details |
| R1292 | DB09303 | approved | biotech | Evolocumab | Indication associated | Details |
| R1334 | DB11107 | experimental | small molecule | Potassium bitartrate | Indication associated | Details |
| R1357 | DB11251 | approved; investigational | small molecule | Tocopherol | Therapeutic strategy associated | Details |
| R1359 | DB11256 | approved; investigational | small molecule | Levomefolic acid | Indication associated | Details |
| R1365 | DB11324 | investigational | small molecule | Nonivamide | Therapeutic strategy associated | Details |
| R1380 | DB11588 | approved; investigational | small molecule | Carbon monoxide | Therapeutic strategy associated | Details |
| R1393 | DB11700 | approved; investigational | small molecule | Setmelanotide | Therapeutic strategy associated | Details |
| R1406 | DB11793 | approved; investigational | small molecule | Niraparib | Therapeutic strategy associated | Details |
| R1417 | DB11921 | approved; investigational | small molecule | Deflazacort | Therapeutic strategy associated | Details |
| R1418 | DB11928 | approved; investigational | biotech | Vosoritide | Therapeutic strategy associated | Details |
| R1419 | DB11936 | approved; investigational | small molecule | Bempedoic acid | Indication associated | Details |
| R1440 | DB12249 | approved; investigational | biotech | Stem bromelain | Therapeutic strategy associated | Details |
| R1488 | DB13191 | nutraceutical | small molecule | Phosphocreatine | Indication associated | Details |
| R1496 | DB13854 | approved; investigational | small molecule | Gamolenic acid | Therapeutic strategy associated | Details |
| R1497 | DB13873 | approved | small molecule | Fenofibric acid | Target associated | Details |
| R1504 | DB13944 | approved | small molecule | Testosterone enanthate | Indication associated | Details |
| R1508 | DB14001 | approved; nutraceutical; vet_approved | small molecule | alpha-Tocopherol succinate | Therapeutic strategy associated | Details |
| R1509 | DB14002 | approved; nutraceutical; vet_approved | small molecule | D-alpha-Tocopherol acetate | Therapeutic strategy associated | Details |
| R1510 | DB14003 | approved | small molecule | alpha-Tocopherol acetate | Therapeutic strategy associated | Details |
| R1525 | DB14538 | experimental; vet_approved | small molecule | Hydrocortisone aceponate | Therapeutic strategy associated | Details |
| R1526 | DB14539 | approved; vet_approved | small molecule | Hydrocortisone acetate | Therapeutic strategy associated | Details |
| R1527 | DB14540 | approved; vet_approved | small molecule | Hydrocortisone butyrate | Therapeutic strategy associated | Details |
| R1528 | DB14541 | approved; investigational; vet_approved | small molecule | Hydrocortisone cypionate | Therapeutic strategy associated | Details |
| R1529 | DB14542 | approved; vet_approved | small molecule | Hydrocortisone phosphate | Therapeutic strategy associated | Details |
| R1530 | DB14543 | approved; vet_approved | small molecule | Hydrocortisone probutate | Therapeutic strategy associated | Details |
| R1531 | DB14544 | approved; vet_approved | small molecule | Hydrocortisone valerate | Therapeutic strategy associated | Details |
| R1545 | DB14845 | approved; investigational | small molecule | Filgotinib | Therapeutic strategy associated | Details |
| R1546 | DB14901 | approved; investigational | biotech | Inclisiran | Indication associated | Details |
| R1556 | DB15119 | approved; investigational | biotech | Ropeginterferon alfa-2b | Therapeutic strategy associated | Details |
| R1559 | DB15354 | approved; investigational | biotech | Evinacumab | Indication associated | Details |
| R1562 | DB15456 | approved; investigational | small molecule | Vericiguat | Indication associated | Details |
| R1577 | DB15742 | investigational | biotech | MultiStem | Therapeutic strategy associated | Details |
| R1590 | DB16165 | approved; investigational | small molecule | Finerenone | Therapeutic strategy associated | Details |
| R1603 | DB16629 | approved | small molecule | Serdexmethylphenidate | Therapeutic strategy associated | Details |