Repositioning Candidates

Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.

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249 records.
Candidate ID Source ID Source Type Compound Type Candidate Name Inclusion Criteria
R1427 DB12007 experimental small molecule Isoflavone Therapeutic strategy associated Details
R1429 DB12023 approved; investigational biotech Benralizumab Therapeutic strategy associated Details
R1434 DB12147 approved; investigational small molecule Erdafitinib Therapeutic strategy associated Details
R1438 DB12240 approved; investigational biotech Polatuzumab vedotin Therapeutic strategy associated Details
R1440 DB12249 approved; investigational biotech Stem bromelain Therapeutic strategy associated Details
R1441 DB12281 approved; investigational biotech Luspatercept Therapeutic strategy associated Details
R1442 DB12328 approved; investigational small molecule Cantharidin Therapeutic strategy associated Details
R1443 DB12332 approved; investigational small molecule Rucaparib Therapeutic strategy associated Details
R1444 DB12340 investigational small molecule Navitoclax Therapeutic strategy associated Details
R1447 DB12442 investigational small molecule Alvespimycin Therapeutic strategy associated Details
R1449 DB12483 approved; investigational small molecule Copanlisib Therapeutic strategy associated Details
R1451 DB12500 approved; investigational small molecule Fedratinib Therapeutic strategy associated Details
R1454 DB12565 investigational small molecule Abexinostat Therapeutic strategy associated Details
R1457 DB12598 investigational small molecule Nafamostat Therapeutic strategy associated Details
R1458 DB12651 investigational small molecule Bardoxolone Therapeutic strategy associated Details
R1471 DB12965 approved; investigational small molecule Silver Therapeutic strategy associated Details
R1472 DB13007 approved; investigational biotech Enfortumab vedotin Therapeutic strategy associated Details
R1475 DB13145 approved; investigational small molecule Nedaplatin Therapeutic strategy associated Details
R1485 DB13174 experimental small molecule Rhein Therapeutic strategy associated Details
R1499 DB13906 experimental biotech Aloe vera leaf Therapeutic strategy associated Details
R1508 DB14001 approved; nutraceutical; vet_approved small molecule alpha-Tocopherol succinate Therapeutic strategy associated Details
R1509 DB14002 approved; nutraceutical; vet_approved small molecule D-alpha-Tocopherol acetate Therapeutic strategy associated Details
R1518 DB14487 approved; investigational small molecule Zinc acetate Therapeutic strategy associated Details
R1524 DB14533 approved; investigational small molecule Zinc chloride Therapeutic strategy associated Details
R1534 DB14631 approved; vet_approved small molecule Prednisolone phosphate Therapeutic strategy associated Details
R1535 DB14635 experimental small molecule Curcumin sulfate Therapeutic strategy associated Details
R1537 DB14669 approved; vet_approved small molecule Betamethasone phosphate Therapeutic strategy associated Details
R1540 DB14731 approved; investigational biotech Tagraxofusp Therapeutic strategy associated Details
R1544 DB14811 approved; investigational biotech Isatuximab Therapeutic strategy associated Details
R1545 DB14845 approved; investigational small molecule Filgotinib Therapeutic strategy associated Details
R1548 DB14962 approved; investigational biotech Trastuzumab deruxtecan Therapeutic strategy associated Details
R1549 DB14967 approved; investigational biotech Margetuximab Therapeutic strategy associated Details
R1553 DB15044 approved; investigational biotech Tafasitamab Therapeutic strategy associated Details
R1558 DB15303 investigational biotech Faricimab Therapeutic strategy associated Details
R1560 DB15442 approved; investigational small molecule Trilaciclib Therapeutic strategy associated Details
R1563 DB15495 experimental small molecule Rocaglamide Therapeutic strategy associated Details
R1564 DB15496 experimental small molecule Didesmethylrocaglamide Therapeutic strategy associated Details
R1565 DB15566 approved; vet_approved small molecule Prednisolone acetate Therapeutic strategy associated Details
R1566 DB15595 approved biotech Ebola Zaire vaccine (live, attenuated) Therapeutic strategy associated Details
R1569 DB15699 approved biotech Brexucabtagene autoleucel Therapeutic strategy associated Details
R1570 DB15719 approved biotech Belantamab mafodotin Therapeutic strategy associated Details
R1571 DB15721 investigational biotech Natural Killer Cell Therapeutic strategy associated Details
R1575 DB15730 investigational biotech Placental Mesenchymal Stem Cells Therapeutic strategy associated Details
R1582 DB15753 investigational biotech Interferon Gamma Therapeutic strategy associated Details
R1597 DB16447 investigational small molecule Thymoquinone Therapeutic strategy associated Details
R1601 DB16620 investigational small molecule Methopterin Therapeutic strategy associated Details
R1602 DB16627 approved; withdrawn small molecule Melphalan flufenamide Therapeutic strategy associated Details
R1606 DB16689 investigational biotech Tengonermin Therapeutic strategy associated Details
R1608 DB16703 approved; investigational small molecule Belumosudil Therapeutic strategy associated Details