Bioactive Compound Details
| Compound ID: | B001129 |
| Source ID: | CHEMBL1138 |
| Source Type: | Small molecule |
| Compound Name: | EZETIMIBE |
| Synonyms: | EZETIMIBE|EZETROL|MK0653|NSC-758923|SCH-58235|SCH58235|Zetia |
| Molecular Formula: | C24H21F2NO3 |
| SMILES: | O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(O)cc2)N1c1ccc(F)cc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T16 | Niemann-Pick C1-like protein 1 | NPC1L1 | inhibitor | Membrane other | Q9UHC9 | NPCL1_HUMAN | Details |