Bioactive Compound Details
| Compound ID: | B114628 |
| Source ID: | CHEMBL2204538 |
| Source Type: | Small molecule |
| Compound Name: | THPP-1 |
| Synonyms: | -- |
| Molecular Formula: | C23H21ClN6O3 |
| SMILES: | COCCOc1nc(-c2ccc(Cl)nc2)nc2c1CN(C(=O)c1ncn3ccccc13)CC2 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T11 | Caspase-3 | CASP3 | inhibitor | Enzyme | P42574 | CASP3_HUMAN | Details |
| T14 | Mitogen-activated protein kinase kinase kinase 5 | MAP3K5 | inhibitor | Enzyme | Q99683 | M3K5_HUMAN | Details |
| T03 | Peroxisome proliferator-activated receptor alpha | PPARA | agonist | Nuclear hormone receptor | Q07869 | PPARA_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |
| T42 | Serine/threonine-protein kinase 17B | STK17B | inhibitor | Kinase | O94768 | ST17B_HUMAN | Details |
| T23 | Type-1 angiotensin II receptor | AGTR1 | antagonist | GPCR | P30556 | AGTR1_HUMAN | Details |