Bioactive Compound Details
| Compound ID: | B126227 |
| Source ID: | CHEMBL35 |
| Source Type: | Small molecule |
| Compound Name: | FUROSEMIDE |
| Synonyms: | ALUZINE 20|ALUZINE 40|ALUZINE 500|Aquamed|DIURESAL|DRYPTAL|Disal|FROOP|FRUMAX|FRUMIL|FRUSEMIDE|FRUSETIC|FRUSID|FRUSOL|FUROSEMIDE|FUROSEMIDUM|Frusemide|HYDROLED|LASIX RET|LB-502|LOGIRENE|Lasix|MARSEMIDE|MIRFAT|NSC-269420|OEDEMEX|RUSYDE|TENKOFRUSE |
| Molecular Formula: | C12H11ClN2O5S |
| SMILES: | NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |