Bioactive Compound Details
| Compound ID: | B126569 |
| Source ID: | CHEMBL359744 |
| Source Type: | Small molecule |
| Compound Name: | DOXORUBICIN HYDROCHLORIDE |
| Synonyms: | ADRIABLASTINA CS|ADRIAMYCIN PFS|ADRIAMYCIN, HYDROCHLORIDE|Adriamycin|Adriamycin rdf|CAELYX|DOXIL (LIPOSOMAL)|DOXORUBICIN CITRATE|DOXORUBICIN CITRIC ACID SALT|DOXORUBICIN HCL|DOXORUBICIN HYDROCHLORIDE|DOXORUBICIN HYDROCHLORIDE (LIPOSOMAL)|DOXORUBICIN LIPOSOMAL COMPLEX OF THE HYDROCHLORIDE|DOXORUBICINI HYDROCHLORIDUM|Doxil|Doxorubicin Hydrochloride|HYDROXYDAUNOMYCIN HYDROCHLORIDE|LIPOSOMAL DOXORUBICIN HYDROCHLORIDE|MYOCET|Rubex |
| Molecular Formula: | C27H30ClNO11 |
| SMILES: | COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.Cl |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |
| T08 | Tumor necrosis factor | TNF | inhibitor | Cytokine | P01375 | TNFA_HUMAN | Details |