Bioactive Compound Details
| Compound ID: | B132669 |
| Source ID: | CHEMBL386630 |
| Source Type: | Small molecule |
| Compound Name: | TESTOSTERONE |
| Synonyms: | ANDROPATCH|AXIRON|Androderm|Androgel|Androgel 1%|Delatestryl|FORTESTA|INTRINSA|NATESTO|NSC-9700|STRIANT|STRIANT SR|TESTIM|TESTODERM|TESTODERM TTS|TESTOGEL|TESTOPATCH|TESTOPEL|TESTORAL|TESTOSTERONE|TESTOSTERONE CIII|TOSTRAN|Testim|Testim 1%|Testosterone|VOGELXO |
| Molecular Formula: | C19H28O2 |
| SMILES: | C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |