Bioactive Compound Details
| Compound ID: | B140090 |
| Source ID: | CHEMBL459 |
| Source Type: | Small molecule |
| Compound Name: | METHYLDOPA |
| Synonyms: | (-)-.ALPHA.-METHYLDOPA|(S)-(-)-.ALPHA.-METHYLDOPA|.ALPHA.-METHYL-L-DOPA|ALPHA-METHYLDOPA|ANHYDROUS METHYLDOPA|Aldomet|BAYER-1440L|DOPAMET|J9.247I|L-.ALPHA.-METHYLDOPA|LEDERDOPA|MEDOMET|METALPHA 250|METALPHA 500|METHYLDOPA|METHYLDOPA (LEVOROTATORY)|METHYLDOPA ANHYDROUS|METHYLDOPA HYDRATE|METHYLDOPA SESQUIHYDRATE|METHYLDOPA, ANHYDROUS|MK-351|NSC-169916|NSC-760080 |
| Molecular Formula: | C10H13NO4 |
| SMILES: | C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O |
| Molecular Species: | ZWITTERION |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T36 | Caspase-6 | CASP6 | inhibitor | Enzyme | P55212 | CASP6_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |