Bioactive Compound Details
| Compound ID: | B143206 |
| Source ID: | CHEMBL55 |
| Source Type: | Small molecule |
| Compound Name: | PENTAMIDINE |
| Synonyms: | GNF-Pf-3680|MB 800 FREE BASE|MB 800 [AS ISETHIONATE]|MB-800|MB-800 (AS ISETHIONATE)|MB-800 FREE BASE|MP-601205|NSC-9921|Nebupent [as isethionate]|PENTACARINAT|PENTAM 300|PENTAMIDINE|PENTAMIDINE ISETIONATE|Pentacarinat [as isethionate]|Pentam 300 [as isethionate]|Pentamidine|RP 2512 FREE BASE|RP 2512 [AS ISETHIONATE)|RP-2512|RP-2512 FREE BASE |
| Molecular Formula: | C19H24N4O2 |
| SMILES: | N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |