Bioactive Compound Details
| Compound ID: | B144966 |
| Source ID: | CHEMBL628 |
| Source Type: | Small molecule |
| Compound Name: | PENTOXIFYLLINE |
| Synonyms: | BL 191|BL-191|C04AD03|NEOTREN MR|NSC-637086|NSC-758481|OXPENTIFYLLINE|OXYPENTIFYLLINE|PENTOXIFYLLINE|PENTOXIPHYLLIN|Pentoxil|TRENTAL 100|TRENTAL 400|Trental |
| Molecular Formula: | C13H18N4O3 |
| SMILES: | CC(=O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T08 | Tumor necrosis factor | TNF | inhibitor | Cytokine | P01375 | TNFA_HUMAN | Details |