Bioactive Compound Details
| Compound ID: | B145005 |
| Source ID: | CHEMBL6466 |
| Source Type: | Small molecule |
| Compound Name: | COUMARIN |
| Synonyms: | 1,2-BENZOPYRONE|CIS-O-COUMARINIC ACID LACTONE|COUMARIN|COUMARIN (PROHIBITED)|COUMARINIC LACTONE|COUMARINUM|CUMARIN|LODEMA|NCI-C07103|NSC-8774|O-HYDROXYCINNAMIC ACID LACTONE|TONKA BEAN CAMPHOR |
| Molecular Formula: | C9H6O2 |
| SMILES: | O=c1ccc2ccccc2o1 |
| Molecular Species: | None |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |