Bioactive Compound Details
| Compound ID: | B145195 |
| Source ID: | CHEMBL717 |
| Source Type: | Small molecule |
| Compound Name: | MEDROXYPROGESTERONE ACETATE |
| Synonyms: | ADGYN MEDRO|AMEN|Amen|CLIMANOR|CURRETAB|CYCRIN|DEPO-PROGEVERA|DEPO-PROVERA|DEPO-PROVERA ONCOLOGY|DEPO-SUBQ PROVERA 104|FARLUTAL|FARLUTAL 100|FARLUTAL 200|FARLUTAL 250|FARLUTAL 500|FARLUTAL INYECTABLE|G03AC06|Lunelle|MEDROXIPROGESTERONE ACETATE|MEDROXYPROGESTERONE|MEDROXYPROGESTERONE 17-ACETATE|MEDROXYPROGESTERONE ACETATE|MEDROXYPROGESTERONI ACETAS|Medroxyprogesterone Acetate|NSC-21171|NSC-26386|NSC-27408|Prempro|Provera|SAYANA PRESS|TV-46046 |
| Molecular Formula: | C24H34O4 |
| SMILES: | CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |