Bioactive Compound Details
| Compound ID: | B145428 |
| Source ID: | CHEMBL817 |
| Source Type: | Small molecule |
| Compound Name: | TOLAZAMIDE |
| Synonyms: | NSC-70762|TOLAZAMIDE|Tolinase|U-17835 |
| Molecular Formula: | C14H21N3O3S |
| SMILES: | Cc1ccc(S(=O)(=O)NC(=O)NN2CCCCCC2)cc1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T45 | Arachidonate 12-lipoxygenase | ALOX12 | inhibitor | Enzyme | P18054 | LOX12_HUMAN | Details |