Bioactive Compound Details
| Compound ID: | B145523 |
| Source ID: | CHEMBL852 |
| Source Type: | Small molecule |
| Compound Name: | MELPHALAN |
| Synonyms: | ALANINE NITROGEN MUSTARD|ALKERAN|Aikeran|CB 3025|CB-3025|L-PAM|L-PHENYLALANINE MUSTARD|L-SARCOLYSIN|MELFALAN|MELPHALAN|NCI-C04853|NSC-241286|NSC-8806|PHENYLALANINE MUSTARD|SARCOLYCIN, L-|SK 15673|SK-15673 |
| Molecular Formula: | C13H18Cl2N2O2 |
| SMILES: | N[C@@H](Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O |
| Molecular Species: | ZWITTERION |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |