Bioactive Compound Details
| Compound ID: | B002710 |
| Source ID: | CHEMBL129 |
| Source Type: | Small molecule |
| Compound Name: | ZIDOVUDINE |
| Synonyms: | 3'-AZT|AZIDOTHYMIDINE|AZT|Azidothymidine|BW A509U|BW-A-509U|BW-A509U|BWA509U|COMPOUND S|COMPOUND-S|NSC-602670|Retrovir|ZIDOVUDINE|ZIDOVUDINUM |
| Molecular Formula: | C10H13N5O4 |
| SMILES: | Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |