Bioactive Compound Details
| Compound ID: | B050446 |
| Source ID: | CHEMBL1480 |
| Source Type: | Small molecule |
| Compound Name: | FELODIPINE |
| Synonyms: | C08CA02|CABREN|CARDIOPLEN XL|FELODIPINE|FELOGEN XL|FELOTENS XL|FOLPIK XL|H 154/82|H-154/82|KELOC SR|NEOFEL XL|NSC-760343|PARMID XL|PINEFELD XL|PRESLOW|Plendil|VASCALPHA |
| Molecular Formula: | C18H19Cl2NO4 |
| SMILES: | CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |