Bioactive Compound Details
| Compound ID: | B074463 |
| Source ID: | CHEMBL157101 |
| Source Type: | Small molecule |
| Compound Name: | KETOCONAZOLE |
| Synonyms: | DAKTARIN GOLD|DAKTARIN INTENSIV|DANDRAZOL|DANDRID|EXTINA|J02AB02|KETOCONAZOLE|KETOCONAZOLUM|KETOPINE|Ketosidin|Ketozole|NIZORAL A-D|NIZORAL ANTI-DANDRUFF|NIZORELLE|NSC-317629|Nizoral|Panfungol|R 41,400|R-41400|Xolegel |
| Molecular Formula: | C26H28Cl2N4O4 |
| SMILES: | CC(=O)N1CCN(c2ccc(OCC3COC(Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |