Bioactive Compound Details
| Compound ID: | B085914 |
| Source ID: | CHEMBL1651534 |
| Source Type: | Small molecule |
| Compound Name: | PF-04457845 |
| Synonyms: | PF-04457845 |
| Molecular Formula: | C23H20F3N5O2 |
| SMILES: | O=C(Nc1cccnn1)N1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T14 | Mitogen-activated protein kinase kinase kinase 5 | MAP3K5 | inhibitor | Enzyme | Q99683 | M3K5_HUMAN | Details |
| T42 | Serine/threonine-protein kinase 17B | STK17B | inhibitor | Kinase | O94768 | ST17B_HUMAN | Details |
| T23 | Type-1 angiotensin II receptor | AGTR1 | antagonist | GPCR | P30556 | AGTR1_HUMAN | Details |