Bioactive Compound Details
| Compound ID: | B096713 |
| Source ID: | CHEMBL185 |
| Source Type: | Small molecule |
| Compound Name: | FLUOROURACIL |
| Synonyms: | 5 FU|5-FLUORURACIL|5-FU|5-Fluorouracil|5.F.U.|ACCUSITE|ACTIKERALL|Adrucil|Carac|EFUDIX|Efudex|FLUORO-URACIL ROCHE|FLUOROURACIL|FLUOROURACILUM|FLUOROURICIL|FLURACIL|Fluoroplex|NSC-19893|PHTHORURACIL|QUEROPLEX|RO 2-9757|RO-2-9757|RO-29757|TOLAK |
| Molecular Formula: | C4H3FN2O2 |
| SMILES: | O=c1[nH]cc(F)c(=O)[nH]1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |