Investigational Drugs
Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.
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581 records.
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D538 | Mazindol | Chemical drug | DB00579 | -- | -- | Under clinical trials | Details |
| D539 | N-Acetylsyctein | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D540 | ninjin'yoeito | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D541 | Olmesartan | Chemical drug | DB00275 | -- | -- | Under clinical trials | Details |
| D542 | Olmesartan Medoxomil | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D543 | Plantago Psyllium and Ocimum Basilicum seeds | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D544 | Pomegranate peel extract | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D545 | Pig placenta extract | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D546 | Proanthocyanidins | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D547 | Qinghua Decoction | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D548 | Rilpivirine | Chemical drug | DB08864 | -- | -- | Under clinical trials | Details |
| D549 | SGLT2 inhibitor | Chemical drug | -- | SGLT2 inhibitor | -- | Under clinical trials | Details |
| D550 | DPP4 inhibitor | Chemical drug | -- | DPP4 inhibitor | -- | Under clinical trials | Details |
| D551 | Sijunzi Decoction | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D552 | TERN-201 | Chemical drug | -- | AOC3 protein inhibitor | Hepatoprotectants | Under clinical trials | Details |
| D553 | TQA3526 | Chemical drug | -- | Farnesoid X-activated receptor agonist | Hepatoprotectants | Under clinical trials | Details |
| D554 | Turmeric and Chicory seeds | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D555 | Vitamin Bs | Supplement | -- | -- | -- | Under clinical trials | Details |
| D556 | Wuwei Baogan Pill | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D557 | Yinchen Linggui decoction | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D558 | Yinchenhao decoction | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D559 | Cynarol | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D560 | Grape seed polyphenols | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D561 | Korea Red Ginseng | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D562 | Levocarnitine Chloride | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D563 | Purslane seeds | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D564 | Rice Bran Nutritional Supplement | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D565 | TurmXtra 60N | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D566 | Zataria multiflora Boiss. | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D567 | IMA-1 | Chemical drug | -- | 12-lipoxygenase (ALOX12)–acetyl-CoA carboxylase 1 (ACC1) inhibitor | -- | Under investigation | Details |
| D568 | ML355 | Chemical drug | -- | 12-lipoxygenase inhibitor | Platelet aggregation inhibitor | Under investigation | Details |
| D570 | INI-678 | Chemical drug | -- | 17-hydroxysteroid dehydrogenase modulators | Antifibrotics; Hepatoprotectants | Under investigation | Details |
| D571 | GW7647 | Miscellany | -- | PPARα agonist | Anti-diabetic drugs | Under investigation | Details |
| D572 | GLP1/2-Fc fusion | Miscellany | -- | GLP-1/GLP-2R dual agonist | Anti-diabetic drugs | Under investigation | Details |
| D573 | Oxyntomodulin analogue | Miscellany | -- | Glucagon like peptide 1 receptor agonists; Glucagon receptor agonists | Anti-diabetic drugs | Under investigation | Details |
| D574 | ND-654 | Chemical drug | -- | Acetyl-CoA carboxylase inhibitor | Enhance lipid metabolism | Under investigation | Details |
| D575 | WZ66 | Miscellany | -- | ACC inhibitor | Enhance lipid metabolism | Under investigation | Details |
| D576 | Hydroxy citrate | Chemical drug | -- | ACLY iinhibitor | Enhance lipid metabolism | Under investigation | Details |
| D577 | Bempedoic acid | Chemical drug | -- | ACLY iinhibitor | Enhance lipid metabolism | Under investigation | Details |
| D578 | 25-HL | Miscellany | -- | SREBP inhibitor | Enhance lipid metabolism | Under investigation | Details |
| D579 | Emfilermin | Miscellany | -- | adipocytes | Enhance lipid metabolism | Under investigation | Details |
| D580 | Tiliamsoine | Miscellany | -- | FXR agonist | Enhance lipid metabolism | Under investigation | Details |
| D581 | sobetirome | Chemical drug | -- | Thyroid hormone receptor beta agonists | Enhance lipid metabolism | Under investigation | Details |
| D582 | EPB-53 | Miscellany | -- | FGF21 agonist | Enhance lipid metabolism | Under investigation | Details |
| D583 | Doxorubicin | Chemical drug | -- | DNA intercalators; Type II DNA topoisomerase inhibitors | Enhance lipid metabolism | Under investigation | Details |
| D584 | shRNA-mediated knockdown of Sms1 | Miscellany | -- | -- | -- | Under investigation | Details |
| D585 | Overexpression of RASSF4 | Miscellany | -- | Ras-association domain family 4 (RASSF4) agonists | -- | Under investigation | Details |
| D586 | CGS21680 | Miscellany | -- | Adenosine A2 receptor agonists | Antiepileptic drugs; Antihypertensives; Antiparkinsonians; Anxiolytics; Neuroprotectants | Under investigation | Details |
| D587 | Fecal microbiota transplantation | Miscellany | -- | -- | -- | Under investigation | Details |
| D588 | Momelotinib | Chemical drug | -- | ACVR1 protein inhibitors; Janus kinase 1 inhibitors; Janus kinase-2 inhibitors | Antineoplastics; Antirheumatics | Under investigation | Details |