| Trial ID: | L0126 |
| Source ID: | NCT04859322
|
| Associated Drug: |
Glucagon
|
| Title: |
The Effect of Lifestyle-induced Hepatic Steatosis on Glucagon-stimulated Amino Acid Turnover
|
| Acronym: |
--
|
| Status: |
Recruiting
|
| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
Non-Alcoholic Fatty Liver Disease|Glucagon Resistance
|
| Interventions: |
Drug: Glucagon
|
| Outcome Measures: |
Nadir of the total amino acid concentration during a two-hour high physiological glucagon infusion during a pancreatic clamp with somatostatin|average slope of the curve describing the change in the total amino acid concentration during 'supraphysiological' glucagon infusion|the incremental area under the curve (iAUC) for total amino acid concentrations during 'supraphysiological' glucagon infusion|the percentage change in amino acid concentration during the last hour of the 'supraphysiological' glucagon infusion as assessed by baseline subtracted AUC
|
| Sponsor/Collaborators: |
Malte Palm Suppli, MD|Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Denmark|Clinical Metabolomics Core Facility, Department of Clinical, Biochemistry, Rigshospitalet, Universit
|
| Gender: |
Male
|
| Age: |
20 Years to 65 Years ?? (Adult, Older Adult)
|
| Phases: |
Not applicable
|
| Enrollment: |
20
|
| Study Type: |
Interventional
|
| Study Designs: |
Allocation: N/A|Intervention Model: Single Group Assignment|Masking: None (Open Label)|Primary Purpose: Basic Science
|
| Start Date: |
February 8, 2021
|
| Completion Date: |
December 9, 2021
|
| Results First Posted: |
--
|
| Last Update Posted: |
April 30, 2021
|
| Locations: |
Center for Clinical Metabolic Research, Hellerup, Copenhagen, Denmark
|
| URL: |
https://ClinicalTrials.gov/show/NCT04859322
|
