| Trial ID: | L0870 |
| Source ID: | IRCT201503273320N11
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| Associated Drug: |
Hydroxy citric Acid
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| Title: |
The effect of weight loss diet with and without Hydroxy citric Acid supplement derived from Garcinia Cambogia on the serum hepcidin level and liver function in women with NAFLD: A randomized controlled clinical trial
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| Acronym: |
--
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| Status: |
Not Recruiting
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| Study Results: |
No Results Available
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| Results: |
--
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| Conditions: |
Non alcoholic fatty liver disease. <br>fatty (change) of liver,not elsewhere classified
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| Interventions: |
Intervention 1: intervention group: weight loss diet plus 6 tablets (2 tablets 30 minutes before: breakfast- lunch - dinner) for 2 months. Intervention 2: control group: just get weight loss diet for 2 months.
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| Outcome Measures: |
Serum level of hepcidin. Timepoint: at baseline,at the end of intervention. Method of measurement: ELIZA Kit.;Liver enzymes( ALT,AST,ALP). Timepoint: at baseline,at the end of intervention. Method of measurement: IFCC.;Liver steatosis. Timepoint: at baseline,at the end of intervention. Method of measurement: liver sonography.;Added at 2017-02-13: high sensivity-C Reactive Protein. Timepoint: Added at 2017-02-13: At the baseline and at the end of intervention. Method of measurement: Added at 2017-02-13: immunoturbidometric.;Added at 2017-02-13: Fasting blood sugar. Timepoint: Added at 2017-02-13: At the baseline and at the end of intervention. Method of measurement: Added at 2017-02-13: Radioimmunoassay.;Added at 2017-02-13: Fasting insulin. Timepoint: Added at 2017-02-13: At the baseline and at the end of intervention. Method of measurement: Added at 2017-02-13: Radioimmunoassay.;Fasting ferritin. Timepoint: At the baseline and at the end of intervention. Method of measurement: ELIZA Kit.;Glycated Hemoglobin. Timepoint: At the baseline and at the end of intervention. Method of measurement: High Performance Liquid Chromatography (HPLC).;Leptin. Timepoint: At the baseline and at the end of intervention. Method of measurement: ELIZA Kit.;Adiponectin. Timepoint: At the baseline and at the end of intervention. Method of measurement: ELIZA Kit.;Lipid profile ( HDL-C, TG,TC). Timepoint: At the baseline and at the end of intervention. Method of measurement: Enzymetic.;Interleukin-1 beta (IL-1??). Timepoint: At the baseline and at the end of intervention. Method of measurement: ELIZA Kit.;Interleukin- 6. Timepoint: At the baseline and at the end of intervention. Method of measurement: ELIZA Kit.;Tumor Necrosis Factor (TNF-a). Timepoint: At the baseline and at the end of intervention. Method of measurement: ELIZA Kit.Anthropometry. Timepoint: at baseline and at the end of intervention. Method of measurement: scale,meter,bioelectrical impedance analyzer.;Energy and nutrients intake. Timepoint: at baseline and at the end of intervention. Method of measurement: 24- hour dietary recall.
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| Sponsor/Collaborators: |
Tabriz University of Medical Sciences
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| Gender: |
Female
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| Age: |
18 years50 years
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| Phases: |
Not applicable
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| Enrollment: |
40
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| Study Type: |
interventional
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| Study Designs: |
Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: From among the patients who volunteer to participate in the study, 40 individuals will be selected by 4-blocks we
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| Start Date: |
27/07/2015
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| Completion Date: |
--
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| Results First Posted: |
--
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| Last Update Posted: |
18 June 2018
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| Locations: |
Iran (Islamic Republic of)
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| URL: |
http://en.irct.ir/trial/3407
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