| Trial ID: | L0925 |
| Source ID: | IRCT2012071810333N1
|
| Associated Drug: |
Vitamin D
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| Title: |
The effect of vitamin D supplementation on serum hepatic enzymes, oxidative stress indicators & inflammatory markers in patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled trial
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| Acronym: |
--
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| Status: |
Not Recruiting
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| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
non alcoholic fatty liver disease. <br>Fatty (change of) liver;Fatty (change of) liver
|
| Interventions: |
Intervention 1: Intervention: One pearl of Vitamin D ( 50000 IU) every other week for 4 months. Intervention 2: Control: Placebo with similarity in physical properties to Vitamin D pearl contains edible paraffin will be prescribed one every other week for
|
| Outcome Measures: |
Alanine Transaminase. Timepoint: Before and after intervention. Method of measurement: U/L - Laboratory kit.;Aspartate transaminase. Timepoint: Before and after intervention. Method of measurement: U/L - Laboratory kit.;Alkaline Phosphatase. Timepoint: before and after intervention. Method of measurement: U/L - laboratory kit.TNF-Alpha. Timepoint: Before and after intervention. Method of measurement: Pg/ml - Laboratory kit.;Insulin Resistance. Timepoint: Before and after intervention. Method of measurement: based on HOMA-IR.;Hs-CRP. Timepoint: Before and after intervention. Method of measurement: Mg/L - Laboratory kit.;Transforming Growth Factor beta (TGF-b). Timepoint: Before and after intervention. Method of measurement: Pg/ml- Laboratory kit.;Cytokeratin-18. Timepoint: Before and after intervention. Method of measurement: U/L - Laboratory kit.;Adiponectin. Timepoint: Before and after intervention. Method of measurement: microgram/ml - laboratory kit.;Malondialdehyde. Timepoint: Before and after intervention. Method of measurement: uM/L- laboratory kit.;Total antioxidant capacity. Timepoint: Before and after intervention. Method of measurement: mM Trolox equivalent- laboratory kit.;Total cholesterol. Timepoint: Before and after intervention. Method of measurement: mg/dl - laboratory kit.;Triglyceride. Timepoint: Before and after intervention. Method of measurement: mg/dl- laboratory kit.;LDL-c. Timepoint: Before and after intervention. Method of measurement: mg/dl - laboratory kit.;HDL-c. Timepoint: Before and after intervention. Method of measurement: mg/dl- laboratory kit.;Serum Vitamin D. Timepoint: Before and after intervention. Method of measurement: ng/ml - laboratory Kit.
|
| Sponsor/Collaborators: |
Ahvaz Jundishapur University of Medical Sciences
|
| Gender: |
All
|
| Age: |
18 years75 years
|
| Phases: |
Not applicable
|
| Enrollment: |
60
|
| Study Type: |
interventional
|
| Study Designs: |
Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment.
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| Start Date: |
14/11/2012
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| Completion Date: |
--
|
| Results First Posted: |
--
|
| Last Update Posted: |
22 February 2018
|
| Locations: |
Iran (Islamic Republic of)
|
| URL: |
http://en.irct.ir/trial/10844
|
