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Pneumothorax suspected secondary to continuous glucose monitor placement in a dog
Publication Year: 2025 Source: Can Vet J PMID: 39781420
The FreeStyle Libre (Abbott) is a human continuous glucose monitor sensor that has been used to monitor glucose concentrations in dogs and cats with diabetes. This sensor and other similar continuous glucose monitoring sensors are increasingly popular in veterinary medicine, specifically for management of diabetes mellitus. The sensor decreases veterinary …
stana: an R package for metagenotyping analysis and interactive application based on clinical data
Publication Year: 2025 Source: NAR Genom Bioinform PMID: 39781512
Metagenotyping of metagenomic data has recently attracted increasing attention as it resolves intraspecies diversity by identifying single nucleotide variants. Furthermore, gene copy number analysis within species provides a deeper understanding of metabolic functions in microbial communities. However, a platform for examining metagenotyping results based on relevant grouping data is lacking. …
Targeting hyaluronan synthesis enhances the therapeutic effectiveness of biologics in inflammatory bowel disease
Publication Year: 2025 Source: JCI Insight PMID: 39782690 DOI: 10.1172/jci.insight.180425
Although biologics have been revolutionizing the treatment of inflammatory bowel diseases (IBD) over the past decade, a significant number of patients still fail to benefit from these drugs. Overcoming the nonresponse to biologics is one of the top challenges in IBD treatment. In this study, we revealed that hyaluronan (HA), …
Approach to anaemia in gastrointestinal disease: A position paper by the ESPGHAN Gastroenterology Committee
Publication Year: 2025 Source: J Pediatr Gastroenterol Nutr PMID: 39783775
Anaemia is a frequent consequence of many gastrointestinal (GI) diseases in children and it can even be the initial presenting symptom of underlying chronic GI disease. The definition of anaemia is age and gender-dependent and it can be classified based on pathophysiology, red cell morphology, and clinical presentation. Although nutritional …
An atypical side effect of TNF alpha inhibitors: acute pleuropericarditis
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 39784708 DOI: 10.17235/reed.2024.10938/2024
Adalimumab is a recombinant human monoclonal antibody that inhibits tumor necrosis factor-alpha (TNF-alpha). It has become an important drug in the treatment of inflammatory bowel diseases (IBD), which do not respond to initial medical treatment. The case of a patient with ulcerative proctitis is presented, who developed acute pleuropericarditis, after …
Inflammatory bowel disease vs strongyloidiasis
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 39784732
We report the case of a 38-year-old woman with a 10-year history of ulcerative proctosigmoiditis. Two months after traveling to Morocco, she developed gastrointestinal symptoms accompanied by eosinophilia in blood tests. Four months later, she progressed to systemic illness with pulmonary involvement. A colonoscopy revealed aphthous ileitis with nonspecific histology …
The Effect of the Size of Gold Nanoparticle Contrast Agents on CT Imaging of the Gastrointestinal Tract and Inflammatory Bowel Disease
Publication Year: 2025 Source: Bioconjug Chem PMID: 39786354 DOI: 10.1021/acs.bioconjchem.4c00507
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD). CT imaging with contrast agents is commonly used for visualizing the gastrointestinal (GI) tract in UC patients. Contrast agents that provide enhanced imaging performance are highly valuable in this field. Recent studies have made significant progress in developing better contrast …
[Visceral perforations in a child with Ehlers-Danlos syndrome type IV]
Publication Year: 2025 Source: Orv Hetil PMID: 39786392
The vascular type IV of Ehlers-Danlos syndrome is an autosomal dominant connective tissue disorder, the diagnosis of which is often delayed. Severe complications: arterial rupture or colon perforation may rarely occur already in childhood. We present a five-year-old child who developed bowel and bladder ruptures. He was admitted with severe …
Microsporidiosis in Patients with Autoimmune Diseases Undergoing Monoclonal Antibody Associated Therapy
Publication Year: 2025 Source: Mycopathologia PMID: 39786641
We present Enterocytozoon bieneusi infection in four patients with autoimmune diseases undergoing prolonged monoclonal antibody therapies. Two patients suffered from inflammatory bowel disease and received anti-TNF therapies, whereas two other patients suffered from systemic lupus erythematosus with renal involvement and received anti-CD20 or anti-BLyS protein therapies. Three out of four …
Temporal trends and patterns for early- and late-onset adult liver cancer incidence vary by race/ethnicity, subsite, and histologic type in the United States from 2000 to 2019
Publication Year: 2025 Source: Cancer Causes Control PMID: 39786651 DOI: 10.1007/s10552-024-01955-4
PURPOSE: To examine incidence trends and patterns for early- and late-onset liver cancer. METHODS: Liver and intrahepatic bile duct (IBD) cancers diagnosed between 2000 and 2019 were acquired from 22 SEER registries. Variables included early-onset (20-49) vs. late-onset (50+), anatomic subsite, histologic type (hepatocellular carcinoma [HCC] and IBD cholangiocarcinoma [ICC]), …
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