Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00346 | 35126843 | World J Hepatol | Is there a role of lipid-lowering therapies in the management of fatty liver disease? | 2022 | Details |
| A00412 | 35093608 | Mol Cell Proteomics | Integrated liver and plasma proteomics in obese mice reveals complex metabolic regulation. | 2022 | Details |
| A00670 | 35008852 | Int J Mol Sci | Role of Microbiota-Derived Metabolites in Alcoholic and Non-Alcoholic Fatty Liver Diseases. | 2021 | Details |
| A00980 | 34911556 | BMC Biol | Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress. | 2021 | Details |
| A02346 | 34408183 | Sci Rep | Key features of the environment promoting liver cancer in the absence of cirrhosis. | 2021 | Details |
| A02602 | 34314306 | Immunopharmacol Immunotoxicol | The effects of guluronic acid (G2013), a new emerging treatment, on inflammatory factors in nonalcoholic steatohepatitis patients under in vitro conditions. | 2021 | Details |
| A02620 | 34307250 | Front Pediatr | Possible Hepatoprotective Effect of Tocotrienol-Rich Fraction Vitamin E in Non-alcoholic Fatty Liver Disease in Obese Children and Adolescents. | 2021 | Details |
| A02815 | 34231659 | Arq Gastroenterol | PERFORMACE OF TRIGLYCERIDE-GLUCOSE INDEX ON DIAGNOSIS AND STAGING OF NAFLD IN OBESE PATIENTS. | 2021 | Details |
| A03015 | 34163108 | World J Gastroenterol | Clinical indicators for progression of nonalcoholic steatohepatitis to cirrhosis. | 2021 | Details |
| A03339 | 34036255 | JHEP Rep | Historical narrative from fatty liver in the nineteenth century to contemporary NAFLD - Reconciling the present with the past. | 2021 | Details |
| A03470 | 33991461 | Physiol Rep | Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice. | 2021 | Details |
| A03763 | 33871418 | Curr Opin Clin Nutr Metab Care | Beyond weight loss in nonalcoholic fatty liver disease: the role of carbohydrate restriction. | 2021 | Details |
| A03786 | 33864571 | Mol Cell Biochem | Upregulated SOCC and IP3R calcium channels and subsequent elevated cytoplasmic calcium signaling promote nonalcoholic fatty liver disease by inhibiting autophagy. | 2021 | Details |
| A03830 | 33855376 | Minerva Surg | NAFLD: a multi-faceted morbid spectrum with uncertain diagnosis and complicated management. | 2021 | Details |
| A03865 | 33839905 | Eur J Nutr | Improving insulin sensitivity, liver steatosis and fibrosis in type 2 diabetes by a food-based digital education-assisted lifestyle intervention program: a feasibility study. | 2021 | Details |
| A04770 | 33511275 | Clin Exp Hepatol | Epidemiology of non-alcoholic fatty liver disease and risk of hepatocellular carcinoma progression. | 2020 | Details |
| A05843 | 33102775 | JGH Open | Determining whether the effect of liraglutide on non-alcoholic fatty liver disease depends on reductions in the body mass index. | 2020 | Details |
| A05844 | 33102766 | JGH Open | Decrease in fasting insulin secretory function correlates with significant liver fibrosis in Japanese non-alcoholic fatty liver disease patients. | 2020 | Details |
| A06068 | 33022287 | Food Chem Toxicol | MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement. | 2020 | Details |
| A07947 | 32302728 | J Hepatol | Exercise retards hepatocarcinogenesis in obese mice independently of weight control. | 2020 | Details |
| A08381 | 32133676 | Aliment Pharmacol Ther | Modelling NAFLD disease burden in four Asian regions-2019-2030. | 2020 | Details |
| A08558 | 32061598 | Gastroenterology | Adipose Tissue-Liver Cross Talk in the Control of Whole-Body Metabolism: Implications in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08566 | 32059982 | J Hepatol | NAFLD as a driver of chronic kidney disease. | 2020 | Details |
| A09239 | 31822739 | Sci Rep | Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling. | 2019 | Details |
| A09295 | 31802390 | Hepatol Int | New drugs for NAFLD: lessons from basic models to the clinic. | 2019 | Details |
| A09827 | 31597406 | Cells | A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10147 | 31470067 | J Hepatol | Transient elastography for screening of liver fibrosis: Cost-effectiveness analysis from six prospective cohorts in Europe and Asia. | 2019 | Details |
| A10345 | 31380833 | J Vis Exp | Inducing and Characterizing Vesicular Steatosis in Differentiated HepaRG Cells. | 2019 | Details |
| A11768 | 30759275 | Mol Genet Genomics | Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model. | 2019 | Details |
| A12529 | 30408605 | Contemp Clin Trials | European paediatric non-alcoholic fatty liver disease registry (EU-PNAFLD): Design and rationale. | 2018 | Details |
| A13731 | 29786565 | Philos Trans R Soc Lond B Biol Sci | Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells. | 2018 | Details |
| A14000 | 29649907 | Expert Opin Ther Pat | Farnesoid X receptor modulators 2014-present: a patent review. | 2018 | Details |
| A14720 | 29271970 | AIDS Rev | Non-Alcoholic Fatty Liver Disease and HIV/AIDS: A New Way of Modulation of Cardiovascular Risk. | 2018 | Details |
| A14722 | 29271504 | Aliment Pharmacol Ther | Utility and cost evaluation of multiparametric magnetic resonance imaging for the assessment of non-alcoholic fatty liver disease. | 2017 | Details |
| A15736 | 28737568 | J Pediatr Gastroenterol Nutr | Systematic Review: Nutrition and Physical Activity in the Management of Paediatric Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A17123 | 27980597 | Nutr Metab (Lond) | Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosis. | 2016 | Details |
| A17324 | 27845265 | J Ethnopharmacol | The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells. | 2016 | Details |
| A17661 | 27680752 | Cell Biol Toxicol | Nonalcoholic fatty liver disease: one entity, multiple impacts on liver health. | 2016 | Details |
| A17745 | 27624887 | Gut | Epigenetics in liver disease: from biology to therapeutics. | 2016 | Details |
| A17871 | 27512407 | Nutr Metab (Lond) | High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs. | 2016 | Details |
| A18069 | 27372863 | Med Hypotheses | Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance. | 2016 | Details |
| A18530 | 30288302 | Hepatol Med Policy | Editor-in-Chief's welcome to Hepatology, Medicine and Policy. | 2016 | Details |
| A19204 | 26703719 | Nutrients | Assessment of Diet and Physical Activity in Paediatric Non-Alcoholic Fatty Liver Disease Patients: A United Kingdom Case Control Study. | 2015 | Details |
| A19919 | 26265792 | Clin Sci (Lond) | Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial. | 2015 | Details |
| A20699 | 25790917 | Biochim Biophys Acta | Peroxisomes compensate hepatic lipid overflow in mice with fatty liver. | 2015 | Details |
| A21009 | 25580206 | Frontline Gastroenterol | Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls. | 2014 | Details |
| A21908 | 24968737 | Endocrine | Does vitamin D improve liver enzymes, oxidative stress, and inflammatory biomarkers in adults with non-alcoholic fatty liver disease? A randomized clinical trial. | 2014 | Details |
| A22876 | 24260182 | PLoS One | The heme oxygenase system rescues hepatic deterioration in the condition of obesity co-morbid with type-2 diabetes. | 2013 | Details |
| A23067 | 24068459 | Eur J Pediatr | Pediatric non-alcoholic fatty liver disease: an increasing public health issue. | 2013 | Details |
| A24409 | 22930399 | Hepatology | Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease. | 2013 | Details |
| A28774 | 35024320 | Acta Pharm Sin B | A small molecule UPR modulator for diabetes identified by high throughput screening. | 2021 | Details |
| A29312 | 34269452 | Transfusion | Temperature mapping in an air ambulance helicopter: Implications for the delivery of pre-hospital transfusion. | 2021 | Details |
| A30441 | 32441510 | ACS Nano | Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis. | 2020 | Details |
| A30655 | 32039387 | JHEP Rep | The mid-infrared spectroscopy: A novel non-invasive diagnostic tool for NASH diagnosis in severe obesity. | 2019 | Details |
| A30802 | 31757853 | Proc Natl Acad Sci U S A | Social behavior for autonomous vehicles. | 2019 | Details |
| A30994 | 31418094 | Environ Monit Assess | Accurate total solar irradiance estimates under irradiance measurements scarcity scenarios. | 2019 | Details |
| A31339 | 30763813 | Accid Anal Prev | Game theoretic model for lane changing: Incorporating conflict risks. | 2019 | Details |
| A33205 | 26475278 | BMC Surg | Long-term prognosis after resection of cryptogenic hepatocellular carcinoma. | 2015 | Details |
| A37113 | 16446999 | Arch Environ Contam Toxicol | Mercury concentrations in gonad, liver, and muscle of white sturgeon Acipenser transmontanus in the lower Columbia River. | 2006 | Details |
| A37506 | 15526543 | Rom J Intern Med | The risk factors of fibrosis in nonalcoholic steatohepatitis. | 2002 | Details |
| A42214 | 35199660 | Curr Opin Clin Nutr Metab Care | Maternal weight and gestational diabetes impacts on child health. | 2022 | Details |
| A43974 | 30265151 | Am J Physiol Heart Circ Physiol | Western diet triggers Toll-like receptor 4 signaling-induced endothelial dysfunction in female Wistar rats. | 2018 | Details |
| A44152 | 29570245 | Obesity (Silver Spring) | Nonnutritive Sweeteners in Weight Management and Chronic Disease: A Review. | 2018 | Details |
| A44482 | 28489415 | Am J Respir Cell Mol Biol | Hepatic Steatosis Accompanies Pulmonary Alveolar Proteinosis. | 2017 | Details |
| A49473 | 35743140 | Int J Mol Sci | Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis. | 2022 | Details |
| A49525 | 35726748 | Pediatr Obes | Possible prediction of obesity-related liver disease in children and adolescents using indices of body composition. | 2022 | Details |
| A49684 | 35671973 | Mol Metab | Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH. | 2022 | Details |
| A50128 | 35509867 | Acta Histochem Cytochem | Label-free Assessment of the Nascent State of Rat Non-alcoholic Fatty Liver Disease Using Spontaneous Raman Microscopy. | 2022 | Details |
| A50667 | 35308229 | Front Pharmacol | Inflammation and Cancer: From the Development of Personalized Indicators to Novel Therapeutic Strategies. | 2022 | Details |
| A50771 | 35272137 | Biomed Pharmacother | The contribution of sterile inflammation to the fatty liver disease and the potential therapies. | 2022 | Details |
| A50830 | 35121749 | Sci Rep | A problem of proportions: estimates of metabolic associated fatty liver disease and liver fibrosis in Australian adults in the nationwide 2012 AusDiab Study. | 2022 | Details |
| A51449 | 35317186 | World J Hepatol | Glycogen hepatopathy in type-1 diabetes mellitus: A case report. | 2022 | Details |
| A52109 | 31103416 | Biochem Pharmacol | Effects of Liraglutide and Fenretinide treatments on the diabetic phenotype of neuronal human BACE1 knock-in mice. | 2019 | Details |
| A52170 | 30464235 | Int J Obes (Lond) | Very low calorie diets are associated with transient ventricular impairment before reversal of diastolic dysfunction in obesity. | 2018 | Details |
| A52311 | 28810615 | Exp Ther Med | Detecting serum and urine metabolic profile changes of CCl4-liver fibrosis in rats at 12 weeks based on gas chromatography-mass spectrometry. | 2017 | Details |
| A52436 | 27138913 | Diabetologia | Neuronal human BACE1 knockin induces systemic diabetes in mice. | 2016 | Details |
| A52931 | 19376605 | J Hepatol | Normoglycemia alone is insufficient to prevent long-term complications of hepatocellular adenoma in glycogen storage disease type Ib mice. | 2009 | Details |