Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06506 | 32849314 | Front Endocrinol (Lausanne) | Fructose Consumption During Pregnancy Influences Milk Lipid Composition and Offspring Lipid Profiles in Guinea Pigs. | 2020 | Details |
| A06509 | 32849276 | Front Endocrinol (Lausanne) | Ceramide Synthases Are Attractive Drug Targets for Treating Metabolic Diseases. | 2020 | Details |
| A06523 | 32841326 | J Clin Endocrinol Metab | Nonalcoholic Fatty Liver Disease and Estimated Insulin Resistance in Obese Youth: A Mendelian Randomization Analysis. | 2020 | Details |
| A06535 | 32833701 | Curr Opin Clin Nutr Metab Care | Lifestyle interventions affecting hepatic fatty acid metabolism. | 2020 | Details |
| A06538 | 32833043 | Arch Toxicol | A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats. | 2020 | Details |
| A06539 | 32832560 | J Diabetes Res | The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A06544 | 32832391 | J Clin Transl Hepatol | Effect of Exercise on NAFLD and Its Risk Factors: Comparison of Moderate versus Low Intensity Exercise. | 2020 | Details |
| A06545 | 32831555 | J Family Community Med | Prevalence and risk factors for nonalcoholic fatty liver disease in obese children in rural Punjab, India. | 2020 | Details |
| A06551 | 32828745 | Clin Res Hepatol Gastroenterol | Myosteatosis in nonalcoholic fatty liver disease: An exploratory study. | 2020 | Details |
| A06561 | 32824723 | Int J Mol Sci | Hypothyroidism-Induced Nonalcoholic Fatty Liver Disease (HIN): Mechanisms and Emerging Therapeutic Options. | 2020 | Details |
| A06564 | 32824337 | Int J Mol Sci | History of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06569 | 32823621 | Nutrients | Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease-A Meta-Analysis. | 2020 | Details |
| A06577 | 32821738 | J Lipid Atheroscler | Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion. | 2020 | Details |
| A06578 | 32821721 | J Lipid Atheroscler | Ceramides: Nutrient Signals that Drive Hepatosteatosis. | 2019 | Details |
| A06581 | 32821071 | World J Gastroenterol | Helicobacter pylori infection: Beyond gastric manifestations. | 2020 | Details |
| A06586 | 32819566 | Biochem Biophys Res Commun | Genetic ablation of Fas-activated serine/threonine kinase ameliorates obesity-related hepatic glucose and lipid metabolic disorders via sirtuin-1 signaling. | 2020 | Details |
| A06592 | 32815965 | Food Funct | A multi-targeting strategy to ameliorate high-fat-diet- and fructose-induced (western diet-induced) non-alcoholic fatty liver disease (NAFLD) with supplementation of a mixture of legume ethanol extracts. | 2020 | Details |
| A06600 | 32812775 | Am J Physiol Gastrointest Liver Physiol | Duodenal-jejunal bypass improves nonalcoholic fatty liver disease independently of weight loss in rodents with diet-induced obesity. | 2020 | Details |
| A06604 | 32810900 | Liver Int | Liver steatosis is highly prevalent and is associated with metabolic risk factors and liver fibrosis in adult patients with type 1 Gaucher disease. | 2020 | Details |
| A06608 | 32810487 | Metabolism | Revealing the role of peroxisome proliferator-activated receptor β/δ in nonalcoholic fatty liver disease. | 2020 | Details |
| A06612 | 32808824 | Can J Physiol Pharmacol | Intricacies of the endothelin system in human obesity: role in the development of complications and potential as a therapeutic target. | 2020 | Details |
| A06613 | 32808114 | J Physiol Biochem | Potential roles of bone morphogenetic protein-9 in glucose and lipid homeostasis. | 2020 | Details |
| A06619 | 32805210 | Chem Biol Interact | High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms. | 2020 | Details |
| A06631 | 32800834 | Life Sci | High fructose intake and the route towards cardiometabolic diseases. | 2020 | Details |
| A06649 | 32795119 | Metab Syndr Relat Disord | Omeprazole and Spirulina Platensis Ameliorate Steatohepatitis in Experimental Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06653 | 32792584 | Sci Rep | Administration of small-molecule guanabenz acetate attenuates fatty liver and hyperglycemia associated with obesity. | 2020 | Details |
| A06654 | 32791802 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of non-alcoholic fatty liver disease in postmenopausal women]. | 2020 | Details |
| A06658 | 32791578 | Clin Mol Hepatol | Beneficial effect of anti-diabetic drugs for nonalcoholic fatty liver disease. | 2020 | Details |
| A06660 | 32791310 | Diabetes Metab | Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes. | 2020 | Details |
| A06662 | 32790863 | Endocrinology | DPP-4 Inhibition with Anagliptin Reduces Lipotoxicity-Induced Insulin Resistance and Steatohepatitis in Male Mice. | 2020 | Details |
| A06667 | 32788075 | Surg Obes Relat Dis | Prevalence of NASH/NAFLD in people with obesity who are currently classified as metabolically healthy. | 2020 | Details |
| A06672 | 32785111 | J Clin Med | Metabolic Footprint, towards Understanding Type 2 Diabetes beyond Glycemia. | 2020 | Details |
| A06676 | 32784205 | BMJ Open Gastroenterol | Association of non-alcoholic fatty liver disease and polycystic ovarian syndrome. | 2020 | Details |
| A06682 | 32781739 | Nutrients | The Root of Polygonum multiflorum Thunb. Alleviates Non-Alcoholic Steatosis and Insulin Resistance in High Fat Diet-Fed Mice. | 2020 | Details |
| A06690 | 32779505 | J Am Heart Assoc | Effects of Epeleuton, a Novel Synthetic Second-Generation n-3 Fatty Acid, on Non-Alcoholic Fatty Liver Disease, Triglycerides, Glycemic Control, and Cardiometabolic and Inflammatory Markers. | 2020 | Details |
| A06694 | 32777482 | Biochim Biophys Acta Mol Cell Biol Lipids | Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions. | 2020 | Details |
| A06704 | 32775098 | Cureus | Vitamin E as an Adjuvant Treatment for Non-alcoholic Fatty Liver Disease in Adults: A Systematic Review of Randomized Controlled Trials. | 2020 | Details |
| A06709 | 32774148 | Mediators Inflamm | Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways. | 2020 | Details |
| A06710 | 32773176 | HPB (Oxford) | Cholecystectomy as a risk factor for non-alcoholic fatty liver disease development. | 2020 | Details |
| A06713 | 32772909 | Comb Chem High Throughput Screen | Evaluation of Insulin Resistance Induced Brain Tissue Dysfunction in Obese Dams and their Neonates: Role of Ipriflavone Amelioration. | 2021 | Details |
| A06715 | 32772323 | J Endocrinol Invest | Testosterone treatment is associated with reduced adipose tissue dysfunction and nonalcoholic fatty liver disease in obese hypogonadal men. | 2020 | Details |
| A06716 | 32771802 | Atherosclerosis | Serum lipoprotein(a) levels and insulin resistance have opposite effects on fatty liver disease. | 2020 | Details |
| A06717 | 32771373 | Peptides | Liraglutide ameliorates lipotoxicity-induced inflammation through the mTORC1 signalling pathway. | 2020 | Details |
| A06722 | 32769877 | Medicine (Baltimore) | Protective effect of probiotics in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A06725 | 32768394 | Ann Endocrinol (Paris) | Impact of aerobic training with and without whole-body vibration training on metabolic features and quality of life in non-alcoholic fatty liver disease patients. | 2020 | Details |
| A06731 | 32766474 | Hepatol Commun | Mortality of NAFLD According to the Body Composition and Presence of Metabolic Abnormalities. | 2020 | Details |
| A06733 | 32766472 | Hepatol Commun | Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study. | 2020 | Details |
| A06751 | 32759940 | Nutr Diabetes | Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice. | 2020 | Details |
| A06752 | 32759852 | Int J Mol Sci | Effective Combination Therapy of Angiotensin-II Receptor Blocker and Rifaximin for Hepatic Fibrosis in Rat Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06756 | 32758573 | Eur J Pharmacol | Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways. | 2020 | Details |
| A06759 | 32757283 | Fundam Clin Pharmacol | Protective effect of fenofibrate against high-fat-high-fructose diet induced non-obese NAFLD in rats. | 2020 | Details |
| A06766 | 32755310 | Am J Physiol Gastrointest Liver Physiol | The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2020 | Details |
| A06767 | 32754976 | Mol Nutr Food Res | Metabolic Inflammation in Obesity-At the Crossroads between Fatty Acid and Cholesterol Metabolism. | 2020 | Details |
| A06775 | 32751794 | Int J Mol Sci | Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice. | 2020 | Details |
| A06776 | 32751772 | Nutrients | Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity. | 2020 | Details |
| A06786 | 32746645 | Expert Rev Gastroenterol Hepatol | Clinical heterogeneity in patients with non-alcoholic fatty liver disease-associated hepatocellular carcinoma. | 2020 | Details |
| A06804 | 32738842 | J Assoc Physicians India | Study and Comparison of Metabolic Profile of Lean and Obese Subjects with Non Alcoholic Fatty Liver Disease. | 2020 | Details |
| A06805 | 32738448 | J Hepatol | Reduced Nogo expression inhibits diet-induced metabolic disorders by regulating ChREBP and insulin activity. | 2020 | Details |
| A06809 | 32738301 | Biochim Biophys Acta Mol Cell Biol Lipids | Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells. | 2020 | Details |
| A06815 | 32736956 | Nutr Metab Cardiovasc Dis | Elevated blood pressure, cardiometabolic risk and target organ damage in youth with overweight and obesity. | 2020 | Details |
| A06822 | 32734012 | Porto Biomed J | An albino mouse model of nonalcoholic fatty liver disease induced using high-fat liquid "Lieber-DeCarli" diet: a preliminary investigation. | 2020 | Details |
| A06824 | 32733933 | Biomed Res Int | Ginsenoside Rb1 Alleviated High-Fat-Diet-Induced Hepatocytic Apoptosis via Peroxisome Proliferator-Activated Receptor γ. | 2020 | Details |
| A06827 | 32733017 | Sci Rep | Determining the contribution of a high-fructose corn syrup formulation to hepatic glycogen synthesis during ad-libitum feeding in mice. | 2020 | Details |
| A06829 | 32731709 | Wiad Lek | Features of some anthropometric indices and indices of insulin resistance in patients with non-alcoholic steatohepatitis on the background of obesity and osteoarthritis. | 2020 | Details |
| A06831 | 32731119 | Cytokine | Osteocalcin and osteoprotegerin levels and their relationship with adipokines and proinflammatory cytokines in children with nonalcoholic fatty liver disease. | 2020 | Details |
| A06837 | 32729704 | Minerva Med | Ancient wheats: beneficial effects on insulin resistance. | 2020 | Details |
| A06843 | 32726654 | Eur J Pharmacol | Neuregulin 4 alleviates hepatic steatosis via activating AMPK/mTOR-mediated autophagy in aged mice fed a high fat diet. | 2020 | Details |
| A06847 | 32725157 | J Clin Endocrinol Metab | Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals. | 2020 | Details |
| A06854 | 32721044 | FASEB J | Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease. | 2020 | Details |
| A06876 | 32713378 | Br J Nutr | Higher flavonoid intake is associated with a lower progression risk of non-alcoholic fatty liver disease in adults: a prospective study. | 2020 | Details |
| A06877 | 32712601 | Aging (Albany NY) | Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. | 2020 | Details |
| A06886 | 32710190 | Diabetologia | Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes. | 2020 | Details |
| A06887 | 32709942 | Sci Rep | Prevalence and staging of non-alcoholic fatty liver disease among patients with heart failure with preserved ejection fraction. | 2020 | Details |
| A06888 | 32708435 | Nutrients | Baseline HOMA IR and Circulating FGF21 Levels Predict NAFLD Improvement in Patients Undergoing a Low Carbohydrate Dietary Intervention for Weight Loss: A Prospective Observational Pilot Study. | 2020 | Details |
| A06889 | 32708059 | Biomedicines | Depression and Cognitive Impairment-Extrahepatic Manifestations of NAFLD and NASH. | 2020 | Details |
| A06890 | 32708036 | Nutrients | The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A06896 | 32706083 | Eur Rev Med Pharmacol Sci | A targeted metabolomic profiling of plasma acylcarnitines in nonalcoholic fatty liver disease. | 2020 | Details |
| A06901 | 32704576 | Endocrinol Diabetes Metab | Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for the management of nonalcoholic fatty liver disease (NAFLD): A systematic review. | 2020 | Details |
| A06912 | 32699301 | Sci Rep | Hyperglycemia-stimulating diet induces liver steatosis in sheep. | 2020 | Details |
| A06914 | 32699106 | BMJ Open Diabetes Res Care | Hepatic fat is a stronger correlate of key clinical and molecular abnormalities than visceral and abdominal subcutaneous fat in youth. | 2020 | Details |
| A06924 | 32696189 | Metab Brain Dis | Melatonin regulates neurodegenerative complications associated with NAFLD via enhanced neurotransmission and cellular integrity: a correlational study. | 2020 | Details |
| A06925 | 32696080 | Clin Res Cardiol | NAFLD and cardiovascular diseases: a clinical review. | 2020 | Details |
| A06936 | 32694178 | Gut | Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites. | 2020 | Details |
| A06942 | 32691411 | Lipids | Alteration of Serum Phospholipid n-6 Polyunsaturated Fatty Acid Compositions in Nonalcoholic Fatty Liver Disease in the Japanese Population: A Cross-Sectional Study. | 2020 | Details |
| A06944 | 32690594 | J Lipid Res | Depletion of adipocyte sphingosine kinase 1 leads to cell hypertrophy, impaired lipolysis, and nonalcoholic fatty liver disease. | 2020 | Details |
| A06946 | 32690265 | Bioorg Med Chem | Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL). | 2020 | Details |
| A06950 | 32690054 | BMC Public Health | Insights from qualitative research on NAFLD awareness with a cohort of T2DM patients: time to go public with insulin resistance? | 2020 | Details |
| A06952 | 32688217 | J Nutr Biochem | Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota. | 2020 | Details |
| A06953 | 32687983 | Environ Toxicol Pharmacol | Early microcystin-LR exposure-linked inflammasome activation in mice causes development of fatty liver disease and insulin resistance. | 2020 | Details |
| A06961 | 32685936 | Explor Med | Nonalcoholic fatty liver disease and portal hypertension. | 2020 | Details |
| A06964 | 32684985 | Diabetol Metab Syndr | NAFLD as a continuum: from obesity to metabolic syndrome and diabetes. | 2020 | Details |
| A06968 | 32683952 | Am J Physiol Gastrointest Liver Physiol | Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease. | 2020 | Details |
| A06972 | 32682086 | Ann Hepatol | Hepatic transcriptome signature correlated with HOMA-IR explains early nonalcoholic fatty liver disease pathogenesis. | 2020 | Details |
| A06976 | 32679761 | Biomolecules | Untargeted Profiling of Bile Acids and Lysophospholipids Identifies the Lipid Signature Associated with Glycemic Outcome in an Obese Non-Diabetic Clinical Cohort. | 2020 | Details |
| A06977 | 32679195 | Arch Biochem Biophys | (-)-Epicatechin and the comorbidities of obesity. | 2020 | Details |
| A06978 | 32679144 | Life Sci | Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease. | 2020 | Details |
| A06986 | 32671767 | Adv Exp Med Biol | Autophagy and Obesity and Diabetes. | 2020 | Details |
| A06990 | 32670822 | J Tradit Complement Med | The synergistic effect of Citrus bergamia and Cynara cardunculus extracts on vascular inflammation and oxidative stress in non-alcoholic fatty liver disease. | 2020 | Details |
| A06994 | 32668273 | Magn Reson Imaging | Noninvasive assessment of abdominal adipose tissues and quantification of hepatic and pancreatic fat fractions in type 2 diabetes mellitus. | 2020 | Details |
| A07007 | 32660189 | Zhonghua Gan Zang Bing Za Zhi | [Pancreatoduodenectomy and non-alcoholic fatty liver disease]. | 2020 | Details |