Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04893 | 33464700 | Kaohsiung J Med Sci | Herp knockout protects against nonalcoholic fatty liver disease in mice on a high fat diet. | 2021 | Details |
| A04896 | 33461969 | BMJ | Management of non-alcoholic fatty liver disease. | 2021 | Details |
| A04898 | 33460786 | Mol Metab | Imaging biomarkers of NAFLD, NASH, and fibrosis. | 2021 | Details |
| A04915 | 33450482 | Biochem Biophys Res Commun | Hypoxia-inducible factor-2 promotes liver fibrosis in non-alcoholic steatohepatitis liver disease via the NF-κB signalling pathway. | 2021 | Details |
| A04918 | 33449917 | Endocr Connect | Pathophysiology of NASH in endocrine diseases. | 2021 | Details |
| A04937 | 33444606 | Metabolism | Elafibranor improves diet-induced nonalcoholic steatohepatitis associated with heart failure with preserved ejection fraction in Golden Syrian hamsters. | 2021 | Details |
| A04938 | 33444517 | Immunol Med | Macrophages as a source of fibrosis biomarkers for non-alcoholic fatty liver disease. | 2021 | Details |
| A04939 | 33443240 | Minerva Gastroenterol Dietol | Hepatic steatosis integrated approach: nutritional guidelines and joined nutraceutical administration. | 2020 | Details |
| A04948 | 33440159 | Cell Rep | Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH. | 2021 | Details |
| A04950 | 33439540 | J Gastroenterol Hepatol | The impact of sodium glucose co-transporter 2 inhibitors on non-alcoholic fatty liver disease. | 2020 | Details |
| A04951 | 33439102 | Am J Physiol Gastrointest Liver Physiol | Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. | 2021 | Details |
| A04958 | 33437901 | Hepatol Commun | Major Histocompatibility Complex Class I-Related Chain A Alleles and Histology of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A04961 | 33437782 | Ann Transl Med | Clinical implications of serum Mac-2-binding protein glycan isomer as a novel biomarker of advanced hepatic fibrosis in diabetes. | 2020 | Details |
| A04968 | 33435509 | Biomedicines | The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model. | 2021 | Details |
| A04969 | 33435415 | Diagnostics (Basel) | Liver Fibrosis Biomarkers Accurately Exclude Advanced Fibrosis and Are Associated with Higher Cardiovascular Risk Scores in Patients with NAFLD or Viral Chronic Liver Disease. | 2021 | Details |
| A04970 | 33434655 | Clin Gastroenterol Hepatol | Diabetes Liver Fibrosis Score to Detect Advanced Fibrosis in Diabetics with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04971 | 33434322 | Hepatology | Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet. | 2021 | Details |
| A04975 | 33431715 | Gut Liver | Clinical and Histologic Features of Patients with Biopsy-Proven Metabolic Dysfunction-Associated Fatty Liver Disease. | 2021 | Details |
| A04977 | 33429859 | Nutrients | Assessment of Lifestyle Factors Helps to Identify Liver Fibrosis Due to Non-Alcoholic Fatty Liver Disease in Obesity. | 2021 | Details |
| A04978 | 33429022 | Free Radic Biol Med | Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress. | 2021 | Details |
| A04980 | 33428035 | Dig Dis Sci | Hepamet Fibrosis Score in Nonalcoholic Fatty Liver Disease Patients in Mexico: Lower than Expected Positive Predictive Value. | 2021 | Details |
| A04982 | 33426569 | J Med Syst | Non-alcoholic Fatty Liver and Liver Fibrosis Predictive Analytics: Risk Prediction and Machine Learning Techniques for Improved Preventive Medicine. | 2021 | Details |
| A04985 | 33425804 | Can J Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: A Bidirectional Relationship. | 2020 | Details |
| A04986 | 33424768 | Front Endocrinol (Lausanne) | Harnessing Muscle-Liver Crosstalk to Treat Nonalcoholic Steatohepatitis. | 2020 | Details |
| A05006 | 33414764 | Front Endocrinol (Lausanne) | FGF19 and FGF21 for the Treatment of NASH-Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human. | 2020 | Details |
| A05017 | 33409399 | Transl Gastroenterol Hepatol | Basic science to clinical trials in non-alcoholic fatty liver disease and alcohol-related liver disease: collaboration with industry. | 2021 | Details |
| A05019 | 33409397 | Transl Gastroenterol Hepatol | Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). | 2021 | Details |
| A05024 | 33407169 | BMC Gastroenterol | Application of artificial intelligence in chronic liver diseases: a systematic review and meta-analysis. | 2021 | Details |
| A05025 | 33406763 | Int J Mol Sci | Immunity as Cornerstone of Non-Alcoholic Fatty Liver Disease: The Contribution of Oxidative Stress in the Disease Progression. | 2021 | Details |
| A05026 | 33406286 | Int J Clin Pract | Small intestinal bacterial overgrowth and non-alcoholic fatty liver disease diagnosed by transient elastography and liver biopsy. | 2021 | Details |
| A05033 | 33400995 | Transl Res | The within-individual reproducibility of the disease severity index from the HepQuant SHUNT test of liver function and physiology. | 2021 | Details |
| A05037 | 33398776 | Hepatol Int | Elobixibat, an ileal bile acid transporter inhibitor, ameliorates non-alcoholic steatohepatitis in mice. | 2021 | Details |
| A05038 | 33398223 | J Clin Exp Hepatol | Effect of COVID-19 on Pre-existing Liver disease: What Hepatologist Should Know? | 2020 | Details |
| A05039 | 33397952 | Nat Commun | Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH. | 2021 | Details |
| A05043 | 33396939 | Int J Mol Sci | Deletion of KLF10 Leads to Stress-Induced Liver Fibrosis upon High Sucrose Feeding. | 2020 | Details |
| A05044 | 33396535 | Int J Mol Sci | Exosomal miRNAs as Potential Biomarkers to Monitor Phosphodiesterase 5 Inhibitor Induced Anti-Fibrotic Effects on CCl4 Treated Rats. | 2020 | Details |
| A05046 | 33395640 | Georgian Med News | [PROGNOSIS ASSESSMENT OF THE COMBINED COURSE OF STABLE CORONARY HEART DISEASE AND NON-ALCOHOLIC STEATOHEPATITIS IN PATIENTS AFTER REVASCULARIZATION INTERVENTIONS]. | 2020 | Details |
| A05047 | 33395434 | PLoS One | Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales. | 2021 | Details |
| A05049 | 33394807 | Eur J Gastroenterol Hepatol | The association of impaired lung function and nonalcoholic fatty liver disease: a systematic review. | 2021 | Details |
| A05050 | 33394549 | Diabetes Obes Metab | Nonalcoholic fatty liver disease, diastolic dysfunction, and impaired myocardial glucose uptake in patients with type 2 diabetes. | 2021 | Details |
| A05051 | 33393329 | Rev Esp Enferm Dig | Liver manifestations in COVID-19 and the influence of pre-existing liver disease in the course of the infection. | 2021 | Details |
| A05054 | 33392234 | Front Med (Lausanne) | Macrophage Markers Do Not Add to the Prediction of Liver Fibrosis by Transient Elastography in Patients With Metabolic Associated Fatty Liver Disease. | 2020 | Details |
| A05058 | 33391254 | Front Immunol | A Mineralocorticoid Receptor Deficiency in Myeloid Cells Reduces Liver Steatosis by Impairing Activation of CD8+ T Cells in a Nonalcoholic Steatohepatitis Mouse Model. | 2020 | Details |
| A05063 | 33390768 | Int J Med Sci | Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function. | 2021 | Details |
| A05064 | 33390398 | J Nutr Sci Vitaminol (Tokyo) | Gene Expression and Histochemical Analyses in the Fatty Livers of Rats Fed a Histidine-Excess Diet. | 2020 | Details |
| A05066 | 33389416 | Dig Dis Sci | A Stepwise Algorithmic Approach and External Validation Study for Noninvasive Prediction of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A05069 | 33388475 | Prostaglandins Leukot Essent Fatty Acids | Regulation of the cytochrome P450 epoxyeicosanoid pathway is associated with distinct histologic features in pediatric non-alcoholic fatty liver disease. | 2020 | Details |
| A05073 | 33387664 | Mitochondrion | Mitochondrial dysfunction as a mechanistic biomarker in patients with non-alcoholic fatty liver disease (NAFLD). | 2020 | Details |
| A05075 | 33386676 | Liver Int | Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD. | 2021 | Details |
| A05080 | 33385317 | J Dig Dis | Efficacy and safety of drugs for nonalcoholic steatohepatitis. | 2021 | Details |
| A05081 | 33384662 | Front Endocrinol (Lausanne) | Chronic Inflammation in Non-Alcoholic Steatohepatitis: Molecular Mechanisms and Therapeutic Strategies. | 2020 | Details |
| A05082 | 33384553 | World J Gastroenterol | Towards an evaluation of alcoholic liver cirrhosis and nonalcoholic fatty liver disease patients with hematological scales. | 2020 | Details |
| A05084 | 33383965 | J Clin Med | The Use of Two-Dimensional Shear Wave Elastography in People with Obesity for the Assessment of Liver Fibrosis in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05085 | 33383448 | Int Immunopharmacol | Therapeutic potential of bicyclol in liver diseases: Lessons from a synthetic drug based on herbal derivative in traditional Chinese medicine. | 2020 | Details |
| A05087 | 33382757 | PLoS One | Nut consumption and the prevalence and severity of non-alcoholic fatty liver disease. | 2020 | Details |
| A05091 | 33381084 | Front Endocrinol (Lausanne) | FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases. | 2020 | Details |
| A05095 | 33378413 | PLoS One | A CD209 ligand and a sialidase inhibitor differentially modulate adipose tissue and liver macrophage populations and steatosis in mice on the Methionine and Choline-Deficient (MCD) diet. | 2020 | Details |
| A05098 | 33377125 | Cell Rep Med | Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes. | 2020 | Details |
| A05103 | 33375190 | Int J Mol Sci | Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein as a Screening Tool for Significant Liver Fibrosis in Health Checkup. | 2020 | Details |
| A05106 | 33374435 | J Clin Med | In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal. | 2020 | Details |
| A05111 | 33372064 | Biol Open | A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference. | 2021 | Details |
| A05112 | 33371482 | Biomolecules | Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants. | 2020 | Details |
| A05116 | 33370454 | J Gastroenterol Hepatol | Association between the severity of liver fibrosis and cardiovascular outcomes in patients with type 2 diabetes. | 2021 | Details |
| A05119 | 33368954 | Diabetes Obes Metab | Pioglitazone and bariatric surgery are the most effective treatments for non-alcoholic steatohepatitis: A hierarchical network meta-analysis. | 2021 | Details |
| A05120 | 33368494 | J Clin Periodontol | Association between periodontitis and fibrotic progression of non-alcoholic fatty liver among Japanese adults. | 2021 | Details |
| A05122 | 33365151 | J Ultrason | Shear wave elastography reveals a high prevalence of liver fibrosis in overweight or obese Hispanic youth. | 2020 | Details |
| A05123 | 33364879 | Sisli Etfal Hastan Tip Bul | The Relationship between Insulin Resistance and Liver Damage in non-alcoholic Fatty Liver Patients. | 2020 | Details |
| A05126 | 33363258 | JGH Open | Association of metabolic-associated fatty liver disease and risk of severe coronavirus disease 2019 illness. | 2020 | Details |
| A05129 | 33362721 | Front Endocrinol (Lausanne) | Oxidation-Specific Epitopes in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05131 | 33362385 | World J Gastroenterol | Untargeted metabolomics characteristics of nonobese nonalcoholic fatty liver disease induced by high-temperature-processed feed in Sprague-Dawley rats. | 2020 | Details |
| A05133 | 33361348 | Gut | RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease. | 2020 | Details |
| A05136 | 33359683 | Free Radic Biol Med | ER stress-induced adipocytes secrete-aldo-keto reductase 1B7-containing exosomes that cause nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A05138 | 33359400 | Mol Metab | Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH. | 2020 | Details |
| A05141 | 33358553 | Ultrasound Med Biol | Use of a convolutional neural network and quantitative ultrasound for diagnosis of fatty liver. | 2020 | Details |
| A05143 | 33358052 | Ultrasound Med Biol | Accuracy of Controlled Attenuation Parameter and Liver Stiffness Measurement in Patients with Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A05146 | 33355256 | Diabetes Care | Advanced Liver Fibrosis Is Common in Patients With Type 2 Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening. | 2020 | Details |
| A05147 | 33354924 | Basic Clin Pharmacol Toxicol | The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis. | 2021 | Details |
| A05148 | 33354866 | Liver Int | Glycogenosis is common in nonalcoholic fatty liver disease and is independently associated with ballooning, but lower steatosis and lower fibrosis. | 2021 | Details |
| A05151 | 33353156 | Int J Mol Sci | Cell Death in Liver Diseases: A Review. | 2020 | Details |
| A05157 | 33350984 | JCI Insight | Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90. | 2021 | Details |
| A05159 | 33350036 | Hepatol Res | A novel rapid immunoassay of serum type IV collagen 7S for the diagnosis of fibrosis stage of nonalcoholic fatty liver diseases. | 2021 | Details |
| A05161 | 33348908 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis: Current Issues and Future Perspectives in Preclinical and Clinical Research. | 2020 | Details |
| A05164 | 33348109 | Nutrition | Development and course of diabetes according to genetic factors and diabetes treatment among patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A05175 | 33346465 | Ter Arkh | [Non-alcoholic fatty liver disease and type 2 diabetes mellitus: issues of the liver fibrosis diagnostics]. | 2020 | Details |
| A05176 | 33346459 | Ter Arkh | [Clinical features of the comorbid course of non-alcoholic fatty liver disease and gallstone disease]. | 2020 | Details |
| A05177 | 33346069 | Mol Metab | Metabolic drivers of non-alcoholic fatty liver disease. | 2020 | Details |
| A05180 | 33345314 | J Cell Physiol | Ghrelin ameliorates nonalcoholic steatohepatitis induced by chronic low-grade inflammation via blockade of Kupffer cell M1 polarization. | 2020 | Details |
| A05186 | 33343375 | Front Pharmacol | Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments. | 2020 | Details |
| A05188 | 33342543 | J Hepatol | Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis. | 2020 | Details |
| A05190 | 33341674 | Biochem Biophys Res Commun | Hepatocyte-specific TAZ deletion downregulates p62/ Sqstm1 expression in nonalcoholic steatohepatitis. | 2020 | Details |
| A05193 | 33341026 | Phytomedicine | Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice. | 2020 | Details |
| A05195 | 33340780 | Clin Gastroenterol Hepatol | Direct Comparison of US and MR Elastography for Staging Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05211 | 33337653 | Cardiol Rev | Part 2: Disease of the Heart and Liver: A Relationship That Cuts Both Ways. | 2020 | Details |
| A05213 | 33336648 | Diabetes Metab Syndr | Nonalcoholic fatty liver disease should be considered for treatment allocation in standard management algorithms for type 2 diabetes. | 2020 | Details |
| A05214 | 33336323 | Patient | Development of a Patient-Reported Outcome Measure for Non-Alcoholic Steatohepatitis (NASH-CHECK): Results of a Qualitative Study. | 2020 | Details |
| A05216 | 33335561 | Therap Adv Gastroenterol | The efficacy of vitamin E in reducing non-alcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression. | 2020 | Details |
| A05218 | 33334622 | Arch Med Res | Epidemiology, Pathogenesis, Diagnosis and Emerging Treatment of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05219 | 33334267 | Int J STD AIDS | Prevalence and predicting factors of metabolic-associated fatty liver disease diagnosed by transient elastography with controlled attenuation parameters in HIV-positive people. | 2020 | Details |
| A05225 | 33333040 | Clin Chim Acta | Development and validation of a noninvasive clinical scoring system to predict significant fibrosis in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A05240 | 33327438 | Int J Mol Sci | Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease. | 2020 | Details |