Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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PPAR2265 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A35932 | 19390649 | PPAR Res | PPAR and liver injury in HIV-infected patients. | 2009 | Details |
| A35969 | 19299451 | Endocrinology | Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling. | 2009 | Details |
| A35996 | 24842131 | Arab J Gastroenterol | Non-invasive fibrosis seromarkers as a predictor of liver fibrosis in chronic hepatitis C and/or non-alcoholic steatohepatitis. | 2009 | Details |
| A35999 | 19248193 | World J Gastroenterol | Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis. | 2009 | Details |
| A36013 | 19205029 | Hepatology | Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A(y) mice. | 2009 | Details |
| A36027 | 19162361 | J Hepatol | Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice. | 2008 | Details |
| A36112 | 18991162 | Scand J Gastroenterol | Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice. | 2009 | Details |
| A36145 | 18941143 | J Lipid Res | The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress. | 2008 | Details |
| A36237 | 18666257 | Hepatology | Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice. | 2008 | Details |
| A36270 | 18571789 | Hepatology | Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis. | 2008 | Details |
| A36302 | 18501395 | Toxicol Appl Pharmacol | Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARalpha with clofibrate. | 2008 | Details |
| A36308 | 18485825 | Lancet Infect Dis | The case for combination antiviral therapy for chronic hepatitis B virus infection. | 2008 | Details |
| A36341 | 18408102 | Gut | Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis. | 2008 | Details |
| A36505 | 17971758 | Molecules | Highly volatile constituents of Vetiveria zizanioides roots grown under different cultivation conditions. | 2006 | Details |
| A36600 | 17654603 | Hepatology | Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C. | 2007 | Details |
| A36622 | 17594812 | Zhonghua Gan Zang Bing Za Zhi | [An experimental study on the reverse mechanism of PPAR-gamma agonist rosiglitazone in rats with non-alcoholic steatohepatitis]. | 2007 | Details |
| A36637 | 17559148 | Hepatology | The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis. | 2007 | Details |
| A36699 | 17436085 | Dig Dis Sci | Rosiglitazone attenuates liver inflammation in a rat model of nonalcoholic steatohepatitis. | 2007 | Details |
| A36710 | 17410441 | Dig Dis Sci | Telmisartan, an angiotensin II type 1 receptor blocker, controls progress of nonalcoholic steatohepatitis in rats. | 2007 | Details |
| A36717 | 17394061 | Dig Dis Sci | Nonalcoholic steatohepatitis (NASH) in ob/ob mice treated with yo jyo hen shi ko (YHK): effects on peroxisome proliferator-activated receptors (PPARs) and microsomal triglyceride transfer protein (MTP). | 2007 | Details |
| A36722 | 17388862 | Intern Med J | Effects of vitamin E treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: results of a pilot study. | 2007 | Details |
| A36768 | 17300698 | Hepatol Res | Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet. | 2007 | Details |
| A36801 | 17241878 | Gastroenterology | Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. | 2006 | Details |
| A36819 | 17177214 | Chemistry | Reaction chemistry of complexes containing Pt--H, Pt--SH, or Pt--S fragments: from their apparent simplicity to the maze of reactions underlying their interconversion. | 2007 | Details |
| A36880 | 17025470 | Phys Rev E Stat Nonlin Soft Matter Phys | Stochasticity and evolutionary stability. | 2006 | Details |
| A36925 | 16936261 | Am J Pathol | A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury. | 2006 | Details |
| A36994 | 16768114 | Nihon Rinsho | [PPAR and NASH]. | 2006 | Details |
| A37047 | 16607244 | Br J Community Nurs | District nurses' triggers for referral of patients to the Macmillan nurse. | 2006 | Details |
| A37053 | 16574099 | Eur J Pharmacol | Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet. | 2006 | Details |
| A37182 | 19079906 | Nutr Res Rev | Therapeutic potential of curcumin in non-alcoholic steatohepatitis. | 2005 | Details |
| A37187 | 16297361 | J Investig Med | Peroxisome proliferator-activated receptor alpha L162V polymorphism in nonalcoholic steatohepatitis and genotype 1 hepatitis C virus-related liver steatosis. | 2005 | Details |
| A37226 | 16216546 | Hepatol Res | Obesity and NASH in Japan. | 2005 | Details |
| A37238 | 16198619 | Hepatol Res | Thiazolidinediones: Pleiotropic drugs with potent anti-inflammatory properties for tissue protection. | 2005 | Details |
| A37276 | 16085455 | Hepatol Res | The peroxisome proliferator-activated receptor-gamma agonist, pioglitazone, inhibits fat accumulation and fibrosis in the livers of rats fed a choline-deficient, l-amino acid-defined diet. | 2005 | Details |
| A37322 | 15959406 | Ann Endocrinol (Paris) | [Nonalcoholic steatohepatitis]. | 2005 | Details |
| A37377 | 15828240 | Nihon Rinsho | [Role of PPARs in the pathophysiology of nonalcoholoic fatty liver disease]. | 2005 | Details |
| A37414 | 15727690 | Zhonghua Gan Zang Bing Za Zhi | [Effect of Endotoxin on the expression of peroxisome proliferator-activated receptor alpha in the development of nonalcoholic steatohepatitis in rats]. | 2005 | Details |
| A37525 | 15482537 | J Gastroenterol Hepatol | Role of polymerase chain reaction and liver biopsy in the evaluation of patients with asymptomatic transaminitis: implications in diagnostic approach. | 2004 | Details |
| A37568 | 15343508 | Hum Pathol | Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens. | 2004 | Details |
| A37835 | 14512888 | Hepatology | Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. | 2003 | Details |
| A37879 | 12883485 | Hepatology | Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E. | 2003 | Details |
| A37886 | 12857433 | Gynecol Endocrinol | Estradiol/progesterone-releasing vaginal rings for hormone replacement therapy in postmenopausal women. | 2003 | Details |
| A37924 | 12767065 | Int J Cancer | HER 2/neu expression and gene amplification in colon cancer. | 2003 | Details |
| A37963 | 12663234 | J Hepatol | Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis. | 2003 | Details |
| A38039 | 12436323 | Orthopade | [Undercutting decompression versus laminectomy. Clinical and radiological results of a prospective controlled trial]. | 2002 | Details |
| A38077 | 12214337 | Rev Gastroenterol Mex | [Treatment of non-alcoholic steatohepatitis (NASH). A comparative study of ursodeoxycholic acid and alpha-tocopherol. A preliminary report]. | 2002 | Details |
| A38302 | 11597543 | Urology | Effective long-term androgen suppression in men with prostate cancer using a hydrogel implant with the GnRH agonist histrelin. | 2001 | Details |
| A38417 | 11296694 | Semin Liver Dis | Etiopathogenesis of nonalcoholic steatohepatitis. | 2001 | Details |
| A38442 | 11232700 | Am J Gastroenterol | A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. | 2001 | Details |
| A38870 | 9707543 | Proc Natl Acad Sci U S A | Cooperation and self-interest: Pareto-inefficiency of Nash equilibria in finite random games. | 1998 | Details |
| A39258 | 9005457 | Rev Chir Orthop Reparatrice Appar Mot | [Selective indications of skull radiography after head injury in children]. | 1996 | Details |
| A39849 | 1445706 | Skin Pharmacol | The possibility of lidocaine ion pair absorption through excised hairless mouse skin. | 1992 | Details |
| A39983 | 2124853 | Nurs Stand | Oncology: the role of the Macmillan nurse. | 1991 | Details |
| A40324 | 3382392 | Biochem Biophys Res Commun | Oxidation of glycerol to formaldehyde by rat liver microsomes. | 1988 | Details |
| A40337 | 3400270 | Xenobiotica | Artifacts in the determination of microsomal xenobiotic N-demethylation in the presence of ascorbic acid tris buffer and Nash reagent. | 1988 | Details |
| A40546 | 3458164 | Proc Natl Acad Sci U S A | Agreement with the disulfide stretching frequency-conformation correlation of Sugeta, Go, and Miyazawa. | 1986 | Details |
| A40658 | 3986141 | Br J Ind Med | Dechlorination of halocarbons by microsomes and vesicular reconstituted cytochrome P-450 systems under reductive conditions. | 1985 | Details |
| A40685 | 2982040 | J Virol | Murine sarcoma virus ts110 RNA transcripts: origin from a single proviral DNA and sequence of the gag-mos junctions in both the precursor and spliced viral RNAs. | 1985 | Details |
| A40814 | 6607422 | No Shinkei Geka | [Disproportionately large communicating fourth ventricle--report of 2 cases]. | 1983 | Details |
| A41080 | 6450487 | Z Erkr Atmungsorgane | [The myocardfunction in chronic obstructive lung diseases with different pathogenesis (author's transl)]. | 1980 | Details |
| A41334 | 933687 | Laryngoscope | Cerebrospinal fluid rhinorrhea via the fossa of Rosenmuller. | 1976 | Details |
| A42218 | 35185572 | Front Pharmacol | Protective Effect of Isoorientin on Oleic Acid-Induced Oxidative Damage and Steatosis in Rat Liver Cells. | 2022 | Details |
| A42248 | 35104011 | FASEB J | NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury. | 2022 | Details |
| A42294 | 34943578 | Diagnostics (Basel) | The Prevalence of Liver Steatosis and Fibrosis Assessed by Vibration-Controlled Transient Elastography and Controlled Attenuation Parameter in Apparently Healthy Romanian Medical Students. | 2021 | Details |
| A42317 | 34887111 | Clin Investig Arterioscler | Bempedoic acid as a PPARα activator: new perspectives for hepatic steatosis treatment in a female rat experimental model. | 2021 | Details |
| A42359 | 34767670 | Biofactors | Vitamin D3 enhances the effects of omega-3 oils against metabolic dysfunction-associated fatty liver disease in rat. | 2021 | Details |
| A42406 | 34621322 | Evid Based Complement Alternat Med | YiQi YangYin Decoction Attenuates Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Rats. | 2021 | Details |
| A42408 | 34617616 | Clin Endocrinol (Oxf) | Long-term health outcomes in young women with polycystic ovary syndrome: A narrative review. | 2021 | Details |
| A42469 | 34455076 | Pharmacol Res | The pivotal role of Nrf2 activators in adipocyte biology. | 2021 | Details |
| A42504 | 34358714 | Cell Mol Gastroenterol Hepatol | Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling. | 2021 | Details |
| A42599 | 34058408 | Clin Gastroenterol Hepatol | Sugar-sweetened Beverages Are Associated With Increased Liver Stiffness and Steatosis Among Apparently Healthy Adults in the United States. | 2021 | Details |
| A42643 | 33916086 | Int J Mol Sci | Fenofibrate Regulates Visceral Obesity and Nonalcoholic Steatohepatitis in Obese Female Ovariectomized C57BL/6J Mice. | 2021 | Details |
| A42675 | 33824670 | J Res Med Sci | The effect of trans-palmitoleic acid on cell viability and sirtuin 1 gene expression in hepatocytes and the activity of peroxisome-proliferator-activated receptor-alpha. | 2020 | Details |
| A42693 | 33746439 | J Clin Exp Hepatol | Nonalcoholic Fatty Liver Disease: Lessons Learnt in the Last Five Years. | 2020 | Details |
| A42698 | 33728291 | Can J Gastroenterol Hepatol | Liver Cancer: Therapeutic Challenges and the Importance of Experimental Models. | 2021 | Details |
| A42710 | 33681679 | Hepatol Commun | Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα-FGF21 Axis. | 2020 | Details |
| A42713 | 33666565 | J Mol Endocrinol | Oleanolic acid derivative HA-20 inhibits adipogenesis in a manner involving PPARγ-FABP4/aP2 pathway. | 2021 | Details |
| A42732 | 33612688 | Intern Med | Potential Effect of a Selective Peroxisome Proliferator-activated Receptor Alpha Modulator on Metabolic Dysfunction-associated Fatty Liver Disease. | 2021 | Details |
| A42777 | 33505493 | Evid Based Complement Alternat Med | Use of Network Pharmacology to Investigate the Mechanism by Which Allicin Ameliorates Lipid Metabolism Disorder in HepG2 Cells. | 2021 | Details |
| A42778 | 33500723 | Theranostics | Activation of N-methyl-D-aspartate receptor regulates insulin sensitivity and lipid metabolism. | 2021 | Details |
| A42806 | 33425000 | Evid Based Complement Alternat Med | Ulmus parvifolia Jacq. Exhibits Antiobesity Properties and Potentially Induces Browning of White Adipose Tissue. | 2020 | Details |
| A42848 | 33299030 | Sci Rep | Author Correction: Perceived stress and non-alcoholic fatty liver disease in apparently healthy men and women. | 2020 | Details |
| A42863 | 33259630 | Toxicol Sci | Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female Offspring. | 2020 | Details |
| A42886 | 33202751 | Pathogens | Porphyromonas gingivalis and Its Systemic Impact: Current Status. | 2020 | Details |
| A42908 | 33142057 | J Med Chem | A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities. | 2020 | Details |
| A42933 | 33045592 | Environ Pollut | 4-Hexylphenol influences adipogenic differentiation and hepatic lipid accumulation in vitro. | 2020 | Details |
| A42937 | 33032848 | J Hepatol | NFATc4: New hub in NASH development. | 2020 | Details |
| A43009 | 32821334 | World J Hepatol | Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling. | 2020 | Details |
| A43153 | 32419825 | Evid Based Complement Alternat Med | Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation. | 2020 | Details |
| A43201 | 32316687 | Nutrients | Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation. | 2020 | Details |
| A43234 | 32222527 | Exp Parasitol | The acute schistosomiasis mansoni ameliorates metabolic syndrome in the C57BL/6 mouse model. | 2020 | Details |
| A43490 | 31590050 | Colloids Surf B Biointerfaces | Fe3O4@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect. | 2019 | Details |
| A43500 | 31576746 | Chem Res Toxicol | Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats. | 2019 | Details |
| A43535 | 31483154 | Am J Physiol Regul Integr Comp Physiol | Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity. | 2019 | Details |
| A43573 | 31378113 | J Int Med Res | Tanshinone IIA ameliorates non-alcoholic fatty liver disease through targeting peroxisome proliferator-activated receptor gamma and toll-like receptor 4. | 2019 | Details |
| A43581 | 31356096 | Arch Iran Med | Comparing Anthropometric Indicators of Visceral and General Adiposity as Determinants of Overall and Cardiovascular Mortality. | 2019 | Details |
| A43657 | 31168510 | Hepatol Commun | Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis. | 2019 | Details |
| A43716 | 31048404 | J Lipid Res | Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption. | 2019 | Details |
| A43822 | 30789748 | Am J Physiol Gastrointest Liver Physiol | Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice. | 2019 | Details |
| A43827 | 30770439 | Proc Natl Acad Sci U S A | PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin. | 2019 | Details |