Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A01111 | 34866849 | J Clin Exp Hepatol | Tobacco, Cigarettes, and the Liver: The Smoking Gun. | 2021 | Details |
| A01114 | 34866842 | J Clin Exp Hepatol | Adipocytokines as Risk Factors for Development of Nonalcoholic Fatty Liver Disease in Children. | 2021 | Details |
| A01118 | 34863942 | Mol Metab | The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease. | 2021 | Details |
| A01119 | 34863940 | Mol Metab | URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and brown adipose tissue whitening in mice. | 2021 | Details |
| A01135 | 34859497 | J Gastroenterol Hepatol | Low serum pancreatic amylase levels as a novel latent risk factor for colorectal adenoma in non-alcohol drinkers. | 2021 | Details |
| A01137 | 34858740 | Cureus | Pioglitazone for the Treatment of Metabolic-Associated Fatty Liver Disease in People Living With HIV and Prediabetes. | 2021 | Details |
| A01138 | 34858322 | Front Endocrinol (Lausanne) | The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review. | 2021 | Details |
| A01144 | 34856688 | Zhonghua Nei Ke Za Zhi | [Correlation between intrahepatic triglyceride content quantified by proton magnetic resonance spectroscopy and glucose metabolism]. | 2021 | Details |
| A01151 | 34853949 | Handb Exp Pharmacol | Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance. | 2021 | Details |
| A01152 | 34853313 | Nat Commun | GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity. | 2021 | Details |
| A01153 | 34851748 | Can J Physiol Pharmacol | The anti-anginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin-induced type 2 diabetes. | 2021 | Details |
| A01154 | 34850865 | Dis Model Mech | Concerted regulation of non-alcoholic fatty liver disease progression by microRNAs in apolipoprotein E-deficient mice. | 2021 | Details |
| A01156 | 34850445 | J Gastroenterol Hepatol | The microbial metabolome in metabolic-associated fatty liver disease. | 2021 | Details |
| A01159 | 34848984 | Diabetes Metab Syndr Obes | Effect of LncPVT1/miR-20a-5p on Lipid Metabolism and Insulin Resistance in NAFLD. | 2021 | Details |
| A01173 | 34841290 | Cell Rep Med | Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease. | 2021 | Details |
| A01174 | 34840719 | Ther Adv Endocrinol Metab | NAFLD in type 1 diabetes: overrated or underappreciated? | 2021 | Details |
| A01176 | 34840086 | J Diabetes Complications | First-degree family history of diabetes is associated with nonalcoholic fatty liver disease independent of glucose metabolic status. | 2021 | Details |
| A01183 | 34836332 | Nutrients | Impact of Genetic Polymorphism on Response to Therapy in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01192 | 34833467 | Medicina (Kaunas) | Correlations between PNPLA3 Gene Polymorphisms and NAFLD in Type 2 Diabetic Patients. | 2021 | Details |
| A01195 | 34831031 | Cells | Bile Acid Receptors and the Gut-Liver Axis in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01198 | 34830360 | Int J Mol Sci | Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD. | 2021 | Details |
| A01202 | 34829926 | Biomedicines | Non-Alcoholic Fatty Liver Disease (NAFLD) and Potential Links to Depression, Anxiety, and Chronic Stress. | 2021 | Details |
| A01211 | 34828697 | Children (Basel) | Association between Hepatic Steatosis and Obstructive Sleep Apnea in Children and Adolescents with Obesity. | 2021 | Details |
| A01220 | 34823548 | J Transl Med | CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype. | 2021 | Details |
| A01224 | 34822647 | Vet Sci | Protective and Therapeutic Effects of Orlistat on Metabolic Syndrome and Oxidative Stress in High-Fat Diet-Induced Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) in Rats: Role on Nrf2 Activation. | 2021 | Details |
| A01233 | 34819792 | Saudi Pharm J | Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease. | 2021 | Details |
| A01237 | 34818080 | Metab Syndr Relat Disord | Increased Serum Pentraxin 3 Is Associated with Prediabetes and Type 2 Diabetes in Obese Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01242 | 34816355 | Obes Surg | Routine Versus Selective Liver Biopsy During Bariatric Surgery: Postoperative Outcomes and Preoperative Predictors of NASH. | 2021 | Details |
| A01243 | 34816009 | JGH Open | Risk factors of nonalcoholic fatty liver disease in lean body mass population: A systematic review and meta-analysis. | 2021 | Details |
| A01252 | 34814152 | Ann Nutr Metab | Inverse Association of Serum Adipsin with the Remission of Nonalcoholic Fatty-Liver Disease: A 3-Year Community-Based Cohort Study. | 2021 | Details |
| A01253 | 34813997 | Biomed Pharmacother | SP-1154, a novel synthetic TGF-β inhibitor, alleviates obesity and hepatic steatosis in high-fat diet-induced mice. | 2021 | Details |
| A01256 | 34813496 | Physiol Int | Effect of vanillic acid and exercise training on fatty liver and insulin resistance in rats: Possible role of fibroblast growth factor 21 and autophagy. | 2021 | Details |
| A01260 | 34811578 | Handb Exp Pharmacol | NAFLD and NASH: The Metabolically Diseased Liver. | 2021 | Details |
| A01267 | 34808500 | Biochem Biophys Res Commun | Endoplasmic reticulum stress increases LECT2 expression via ATF4. | 2021 | Details |
| A01270 | 34808224 | J Pediatr | Comparison of the Triglyceride Glucose Index and Modified Triglyceride Glucose Indices to Predict Nonalcoholic Fatty Liver Disease in Youths. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01279 | 34803916 | Front Endocrinol (Lausanne) | Sestrin2 as a Potential Target for Regulating Metabolic-Related Diseases. | 2021 | Details |
| A01280 | 34803681 | Front Pharmacol | The Effects of Vitamin D Supplementation on Anthropometric and Biochemical Indices in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2021 | Details |
| A01294 | 34798892 | BMC Complement Med Ther | Effect of cranberry supplementation on liver enzymes and cardiometabolic risk factors in patients with NAFLD: a randomized clinical trial. | 2021 | Details |
| A01308 | 34794234 | Biomed Pharmacother | Saroglitazar and Hepano treatment offers protection against high fat high fructose diet induced obesity, insulin resistance and steatosis by modulating various class of hepatic and circulating lipids. | 2021 | Details |
| A01309 | 34794182 | Semin Liver Dis | The Neglected Role of Bile Duct Epithelial Cells in NASH. | 2021 | Details |
| A01318 | 34789138 | Curr Med Imaging | Evaluation of Aortic Distensibility in Patients with Nonalcoholic Fatty Liver using CT. | 2021 | Details |
| A01339 | 34783554 | J Agric Food Chem | Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition. | 2021 | Details |
| A01343 | 34781143 | Biomed Pharmacother | Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction. | 2021 | Details |
| A01345 | 34780166 | Chem Res Toxicol | Differential Roles of Water-Insoluble and Water-Soluble Fractions of Diesel Exhaust Particles in the Development of Adverse Health Effects Due to Chronic Instillation of Diesel Exhaust Particles. | 2021 | Details |
| A01346 | 34780030 | Hepatol Int | Impact of non-alcoholic fatty liver disease on the risk of sarcopenia: a nationwide multicenter prospective study. | 2021 | Details |
| A01347 | 34779535 | Hepatology | Effect of diabetes medications and glycemic control on risk of hepatocellular cancer in patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A01348 | 34779464 | Food Funct | MUFA in metabolic syndrome and associated risk factors: is MUFA the opposite side of the PUFA coin? | 2021 | Details |
| A01357 | 34776827 | Food Nutr Res | Weissella cibaria MG5285 and Lactobacillus reuteri MG5149 attenuated fat accumulation in adipose and hepatic steatosis in high-fat diet-induced C57BL/6J obese mice. | 2021 | Details |
| A01368 | 34773257 | Hepatology | A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome. | 2021 | Details |
| A01373 | 34771023 | Molecules | Zinc as a Drug for Wilson's Disease, Non-Alcoholic Liver Disease and COVID-19-Related Liver Injury. | 2021 | Details |
| A01374 | 34769488 | Int J Mol Sci | The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases. | 2021 | Details |
| A01377 | 34769060 | Int J Mol Sci | Pathophysiological Molecular Mechanisms of Obesity: A Link between MAFLD and NASH with Cardiovascular Diseases. | 2021 | Details |
| A01378 | 34768942 | Int J Mol Sci | In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia. | 2021 | Details |
| A01381 | 34768440 | J Clin Med | Prothrombotic and Inflammatory Markers in Elderly Patients with Non-Alcoholic Hepatic Liver Disease before and after Weight Loss: A Pilot Study. | 2021 | Details |
| A01386 | 34764881 | Front Physiol | Green Plant Pigment, Chlorophyllin, Ameliorates Non-alcoholic Fatty Liver Diseases (NAFLDs) Through Modulating Gut Microbiome in Mice. | 2021 | Details |
| A01389 | 34763561 | J Int Med Res | Does the FT3-to-FT4 ratio easily predict the progression of NAFLD and NASH cirrhosis? | 2021 | Details |
| A01400 | 34759828 | Front Pharmacol | Hepatopathy Associated With Type 1 Diabetes: Distinguishing Non-alcoholic Fatty Liver Disease From Glycogenic Hepatopathy. | 2021 | Details |
| A01401 | 34759311 | Nat Commun | Elevated circulating follistatin associates with an increased risk of type 2 diabetes. | 2021 | Details |
| A01403 | 34758930 | Arch Pediatr | The role of nutrition in non-alcoholic fatty liver disease treatment in obese children. | 2021 | Details |
| A01413 | 34757046 | Mol Metab | Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis. | 2021 | Details |
| A01433 | 34749354 | Hum Hered | Association of PNPLA3 I148M with Liver Disease Biomarkers in Latinos. | 2021 | Details |
| A01443 | 34743980 | Eur J Pharmacol | Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms. | 2021 | Details |
| A01466 | 34737121 | J Mol Cell Cardiol | NAFLD as a continuous driver in the whole spectrum of vascular disease. | 2021 | Details |
| A01470 | 34736334 | Ceska Gynekol | Conservative possibilities influencing PCOS syndrome - the importance of nutrition. | 2021 | Details |
| A01472 | 34734674 | Pediatr Obes | Exercise dose on hepatic fat and cardiovascular health in adolescents with excess of adiposity. | 2021 | Details |
| A01473 | 34734480 | J Cell Mol Med | Exercise ameliorates insulin resistance and improves ASK1-mediated insulin signalling in obese rats. | 2021 | Details |
| A01476 | 34734090 | J Immunol Res | Mangiferin Ameliorates HFD-Induced NAFLD through Regulation of the AMPK and NLRP3 Inflammasome Signal Pathways. | 2021 | Details |
| A01484 | 34729306 | Acta Pharm Sin B | 3D disorganization and rearrangement of genome provide insights into pathogenesis of NAFLD by integrated Hi-C, Nanopore, and RNA sequencing. | 2021 | Details |
| A01485 | 34728268 | Presse Med | Complications of lipodystrophy syndromes. | 2021 | Details |
| A01490 | 34726357 | J Pediatr Endocrinol Metab | Increased hepcidin levels and non-alcoholic fatty liver disease in obese prepubertal children: a further piece to the complex puzzle of metabolic derangements. | 2021 | Details |
| A01492 | 34726148 | Proc Nutr Soc | Dysregulation of hepatic metabolism with obesity: factors influencing glucose and lipid metabolism. | 2021 | Details |
| A01501 | 34722019 | Cureus | Decoding the Pathophysiology of Non-alcoholic Fatty Liver Disease Progressing to Non-alcoholic Steatohepatitis: A Systematic Review. | 2021 | Details |
| A01504 | 34719614 | J Nutr Sci Vitaminol (Tokyo) | Effect of Hyperbaric Oxygen Therapy (HBOT) on Insulin Resistance Associated with Abdominal Obesity in Wistar Rats with Dietary Sucrose-Induced Metabolic Syndrome. | 2021 | Details |
| A01508 | 34717194 | Int Immunopharmacol | Oridonin regulates the polarized state of Kupffer cells to alleviate nonalcoholic fatty liver disease through ROS-NF-κB. | 2021 | Details |
| A01513 | 34712528 | Cureus | An Emerging Facet of Diabetes Mellitus: The Nexus of Gastrointestinal Disorders. | 2021 | Details |
| A01518 | 34711595 | BMJ Open | Association between complement C3 and the prevalence of metabolic-associated fatty liver disease in a Chinese population: a cross-sectional study. | 2021 | Details |
| A01520 | 34710482 | J Hepatol | Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease. | 2021 | Details |
| A01530 | 34707570 | Front Endocrinol (Lausanne) | Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk. | 2021 | Details |
| A01537 | 34706542 | J Agric Food Chem | Sulforaphane Regulates Glucose and Lipid Metabolisms in Obese Mice by Restraining JNK and Activating Insulin and FGF21 Signal Pathways. | 2021 | Details |
| A01540 | 34704339 | Trop Med Int Health | Hepatic steatosis is associated with anthropometry, cardio-metabolic disease risk, sex, age and urbanisation, but not with ethnicity in adult Kenyans. | 2021 | Details |
| A01543 | 34704005 | JHEP Rep | PI3Kγ promotes obesity-associated hepatocellular carcinoma by regulating metabolism and inflammation. | 2021 | Details |
| A01544 | 34703257 | Diabetes Metab Syndr Obes | QSHY Granules Promote White Adipose Tissue Browning and Correct BCAAs Metabolic Disorder in NAFLD Mice. | 2021 | Details |
| A01546 | 34699301 | Adipocyte | Verapamil induces autophagy to improve liver regeneration in non-alcoholic fatty liver mice. | 2021 | Details |
| A01550 | 34697666 | Handb Exp Pharmacol | Obesity and Obstructive Sleep Apnea. | 2021 | Details |
| A01555 | 34695228 | Eur J Clin Invest | Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis. | 2021 | Details |
| A01563 | 34692739 | Front Med (Lausanne) | Hypoxia-Inducible Factors as Key Players in the Pathogenesis of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis. | 2021 | Details |
| A01564 | 34692725 | Front Med (Lausanne) | PNPLA3, TM6SF2, and MBOAT7 Influence on Nutraceutical Therapy Response for Non-alcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2021 | Details |
| A01577 | 34687092 | Biofactors | Perspectives in liver redox imbalance: Toxicological and pharmacological aspects underlying iron overloading, nonalcoholic fatty liver disease, and thyroid hormone action. | 2021 | Details |
| A01584 | 34684698 | Molecules | Natural Aporphine Alkaloids with Potential to Impact Metabolic Syndrome. | 2021 | Details |
| A01586 | 34684586 | Nutrients | Time-Restricted Feeding during Puberty Ameliorates Adiposity and Prevents Hepatic Steatosis in a Mouse Model of Childhood Obesity. | 2021 | Details |
| A01587 | 34684533 | Nutrients | Supplementation with a Specific Combination of Metabolic Cofactors Ameliorates Non-Alcoholic Fatty Liver Disease, Hepatic Fibrosis, and Insulin Resistance in Mice. | 2021 | Details |
| A01591 | 34684404 | Nutrients | Association between Fasting Ketonuria and Advanced Liver Fibrosis in Non-Alcoholic Fatty Liver Disease Patients without Prediabetes and Diabetes Mellitus. | 2021 | Details |
| A01599 | 34681787 | Int J Mol Sci | The Interplay between Insulin Resistance, Inflammation, Oxidative Stress, Base Excision Repair and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01612 | 34680476 | Biomedicines | Genetics Is of the Essence to Face NAFLD. | 2021 | Details |
| A01613 | 34680463 | Biomedicines | Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges. | 2021 | Details |
| A01614 | 34679681 | Antioxidants (Basel) | Ameliorative Effect of Annona muricata (Graviola) Extract on Hyperglycemia Induced Hepatic Damage in Type 2 Diabetic Mice. | 2021 | Details |
| A01622 | 34678374 | Toxicol Appl Pharmacol | Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3. | 2021 | Details |
| A01623 | 34678296 | Clin Chim Acta | The potential pathophysiological role of altered lipid metabolism and electronegative low-density lipoprotein (LDL) in non-alcoholic fatty liver disease and cardiovascular diseases. | 2021 | Details |
| A01624 | 34677420 | Metabolites | Molecular Mechanisms of the SLC13A5 Gene Transcription. | 2021 | Details |