Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A22471 | 24534255 | Toxicol Appl Pharmacol | PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells. | 2014 | Details |
| A22489 | 24520264 | Exp Ther Med | Comparison between the efficacies of curcumin and puerarin in C57BL/6 mice with steatohepatitis induced by a methionine- and choline-deficient diet. | 2013 | Details |
| A22495 | 24517411 | Metab Syndr Relat Disord | Comparative effects of the renin-angiotensin system blockers on nonalcoholic fatty liver disease and insulin resistance in C57BL/6 mice. | 2014 | Details |
| A22524 | 24492282 | Lab Invest | Increased expression of c-Jun in nonalcoholic fatty liver disease. | 2014 | Details |
| A22529 | 24489777 | PLoS One | Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats. | 2014 | Details |
| A22533 | 24486698 | Mol Cell Endocrinol | Nonalcoholic steatohepatitis as a novel player in metabolic syndrome-induced erectile dysfunction: an experimental study in the rabbit. | 2014 | Details |
| A22537 | 24481563 | J Physiol Biochem | Effects of binge ethanol on lipid homeostasis and oxidative stress in a rat model of nonalcoholic fatty liver disease. | 2014 | Details |
| A22549 | 24473773 | Aging (Albany NY) | SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation. | 2014 | Details |
| A22551 | 24469900 | Arch Toxicol | A simple transcriptomic signature able to predict drug-induced hepatic steatosis. | 2014 | Details |
| A22555 | 24464605 | Hepatology | Reduced adiponectin signaling due to weight gain results in nonalcoholic steatohepatitis through impaired mitochondrial biogenesis. | 2014 | Details |
| A22571 | 24456353 | J Med Food | Cooked rice inhibits hepatic fat accumulation by regulating lipid metabolism-related gene expression in mice fed a high-fat diet. | 2014 | Details |
| A22573 | 24454937 | PLoS One | Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis. | 2014 | Details |
| A22581 | 24445216 | J Hepatol | Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice. | 2014 | Details |
| A22603 | 24419221 | Nat Commun | Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease. | 2014 | Details |
| A22615 | 24411941 | Cell Metab | Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers. | 2014 | Details |
| A22626 | 24401223 | Atherosclerosis | Cardiovascular risk, lipidemic phenotype and steatosis. A comparative analysis of cirrhotic and non-cirrhotic liver disease due to varying etiology. | 2013 | Details |
| A22633 | 24395441 | J Cell Physiol | Protective effect of the Y220C mutant p53 against steatosis: good news? | 2014 | Details |
| A22634 | 24393106 | Antioxid Redox Signal | Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin. | 2014 | Details |
| A22642 | 24388885 | J Physiol Pharmacol | Apolipoprotein E4 allele is associated with substantial changes in the plasma lipids and hyaluronic acid content in patients with nonalcoholic fatty liver disease. | 2013 | Details |
| A22647 | 24384368 | Semin Cell Dev Biol | Nuclear envelope-related lipodystrophies. | 2013 | Details |
| A22653 | 24380887 | Biochem Pharmacol | Brain metabolic dysfunction at the core of Alzheimer's disease. | 2013 | Details |
| A22658 | 24378273 | Ann Hepatol | Effects of bile acid sequestration on hepatic steatosis in obese mice. | 2014 | Details |
| A22683 | 26058106 | Eksp Klin Gastroenterol | [New metabolic index in the diagnosis of insulin resistance in patients with nonalcoholic fatty liver disease]. | 2014 | Details |
| A22693 | 25842663 | Eksp Klin Gastroenterol | [Prevalence of nonalcoholic fatty liver disease in young patients with abdominal obesity and hypertension]. | 2014 | Details |
| A22697 | 25796866 | Wiad Lek | [Variants of the course of non-alcoholic fatty liver disease in patients with ischemic heart disease and possibility of hypolipidemic therapy]. | 2014 | Details |
| A22700 | 25796814 | Wiad Lek | Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis. | 2014 | Details |
| A22705 | 24368431 | J Nutr | Choline supplementation protects against liver damage by normalizing cholesterol metabolism in Pemt/Ldlr knockout mice fed a high-fat diet. | 2013 | Details |
| A22713 | 24363514 | World J Gastroenterol | Cross-talk between the thyroid and liver: a new target for nonalcoholic fatty liver disease treatment. | 2013 | Details |
| A22714 | 24362075 | J Hepatol | Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation. | 2013 | Details |
| A22723 | 24356885 | Am J Physiol Gastrointest Liver Physiol | Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. | 2013 | Details |
| A22728 | 24353111 | Biofactors | Novel insights on interactions between folate and lipid metabolism. | 2013 | Details |
| A22732 | 24349208 | PLoS One | Hepatic crown-like structure: a unique histological feature in non-alcoholic steatohepatitis in mice and humans. | 2013 | Details |
| A22741 | 24342243 | Food Chem Toxicol | The ethanol extract of Zingiber zerumbet Smith attenuates non-alcoholic fatty liver disease in hamsters fed on high-fat diet. | 2013 | Details |
| A22746 | 24335764 | Int J Obes (Lond) | Kefir improves fatty liver syndrome by inhibiting the lipogenesis pathway in leptin-deficient ob/ob knockout mice. | 2013 | Details |
| A22750 | 24333182 | J Hepatol | Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated downregulation of FXR in aging mice. | 2013 | Details |
| A22752 | 24329852 | J Viral Hepat | Hepatitis C and lipid metabolism, hepatic steatosis, and NAFLD: still important in the era of direct acting antiviral therapy? | 2013 | Details |
| A22757 | 24327268 | Hepatology | Hepatocyte-specific Ptpn6 deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: potential role of PPARγ. | 2014 | Details |
| A22762 | 24324835 | PLoS One | Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome. | 2013 | Details |
| A22773 | 24317120 | Nat Med | Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy. | 2013 | Details |
| A22776 | 24316260 | Gastroenterology | Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease. | 2013 | Details |
| A22802 | 24292949 | Genes Nutr | Dietary supplementation with soy isoflavones or replacement with soy proteins prevents hepatic lipid droplet accumulation and alters expression of genes involved in lipid metabolism in rats. | 2013 | Details |
| A22808 | 26355775 | J Clin Transl Hepatol | Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Epidemiology, Pathogenesis, and Prevention. | 2013 | Details |
| A22825 | 24282628 | Oxid Med Cell Longev | Dietary anthocyanins as nutritional therapy for nonalcoholic fatty liver disease. | 2013 | Details |
| A22834 | 24275070 | Toxicol Appl Pharmacol | Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. | 2013 | Details |
| A22836 | 24274878 | Clin Liver Dis | Host genetic variants in obesity-related nonalcoholic fatty liver disease. | 2013 | Details |
| A22845 | 24274867 | Clin Liver Dis | The role of diet and nutritional intervention for the management of patients with NAFLD. | 2013 | Details |
| A22848 | 24274863 | Clin Liver Dis | The impact of obesity on liver histology. | 2013 | Details |
| A22851 | 24273892 | Pharmazie | Celastrus orbiculatus Thunb. ameliorates high-fat diet-induced non-alcoholic fatty liver disease in guinea pigs. | 2013 | Details |
| A22859 | 24251697 | J Gastroenterol Hepatol | Role of the gut microbiota in human nutrition and metabolism. | 2013 | Details |
| A22869 | 24265237 | Compr Physiol | Steatosis in the liver. | 2013 | Details |
| A22886 | 24253218 | Int J Mol Med | Metformin prevents hepatic steatosis by regulating the expression of adipose differentiation-related protein. | 2013 | Details |
| A22894 | 24239806 | Toxicol Lett | Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. | 2013 | Details |
| A22897 | 24228201 | Adv Nutr | Hepatic fatty acid trafficking: multiple forks in the road. | 2013 | Details |
| A22898 | 24226095 | J Biol Chem | Retinoic acid-related orphan receptor α regulates diurnal rhythm and fasting induction of sterol 12α-hydroxylase in bile acid synthesis. | 2013 | Details |
| A22899 | 24224789 | Acta Physiol (Oxf) | Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring. | 2014 | Details |
| A22901 | 24222948 | World J Gastroenterol | Interaction of IFNL3 with insulin resistance, steatosis and lipid metabolism in chronic hepatitis C virus infection. | 2013 | Details |
| A22903 | 24222941 | World J Gastroenterol | PNPLA3 I148M polymorphism and progressive liver disease. | 2013 | Details |
| A22905 | 24222094 | Semin Liver Dis | PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease. | 2013 | Details |
| A22906 | 24222092 | Semin Liver Dis | The role of gastrointestinal hormones in hepatic lipid metabolism. | 2013 | Details |
| A22908 | 24222090 | Semin Liver Dis | The unfolded protein response in fatty liver disease. | 2013 | Details |
| A22912 | 24219083 | J Gastroenterol Hepatol | Apolipoprotein A-I and adenosine triphosphate-binding cassette transporter A1 expression alleviates lipid accumulation in hepatocytes. | 2014 | Details |
| A22921 | 24209497 | Lipids Health Dis | Nonalcoholic fatty liver disease: molecular pathways and therapeutic strategies. | 2013 | Details |
| A22946 | 24187469 | World J Gastroenterol | Effects of probiotics on nonalcoholic fatty liver disease: a meta-analysis. | 2013 | Details |
| A22949 | 24185692 | Nat Med | Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. | 2013 | Details |
| A22966 | 24166662 | Dig Dis Sci | Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats. | 2013 | Details |
| A22979 | 24142602 | Eur Rev Med Pharmacol Sci | Curcumin decreases oleic acid-induced lipid accumulation via AMPK phosphorylation in hepatocarcinoma cells. | 2013 | Details |
| A22981 | 24140006 | Prostaglandins Leukot Essent Fatty Acids | A diet high in α-linolenic acid and monounsaturated fatty acids attenuates hepatic steatosis and alters hepatic phospholipid fatty acid profile in diet-induced obese rats. | 2013 | Details |
| A22983 | 24134913 | Biochem Pharmacol | Morin reduces hepatic inflammation-associated lipid accumulation in high fructose-fed rats via inhibiting sphingosine kinase 1/sphingosine 1-phosphate signaling pathway. | 2013 | Details |
| A23019 | 24114819 | Ann Hepatol | Pioglitazone upregulates hepatic angiotensin converting enzyme 2 expression in rats with steatohepatitis. | 2014 | Details |
| A23020 | 24113768 | Am J Physiol Gastrointest Liver Physiol | Lactobacillus casei strain Shirota protects against nonalcoholic steatohepatitis development in a rodent model. | 2013 | Details |
| A23023 | 24106929 | Liver Int | Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease. | 2013 | Details |
| A23036 | 24086498 | PLoS One | Coordinated and interactive expression of genes of lipid metabolism and inflammation in adipose tissue and liver during metabolic overload. | 2013 | Details |
| A23041 | 24084163 | Mol Genet Metab | Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: effect of dietary methyl donor supplementation. | 2013 | Details |
| A23076 | 24064383 | Free Radic Biol Med | CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. | 2013 | Details |
| A23091 | 24047346 | Ultrastruct Pathol | What's in a name?-"Lipolysosome": ultrastructural features of a lipid-containing organelle. | 2013 | Details |
| A23094 | 24044579 | Lipids Health Dis | Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats. | 2013 | Details |
| A23101 | 24040873 | Curr Pharm Des | The role of oral antidiabetic agents and incretin mimetics in type 2 diabetic patients with non-alcoholic fatty liver disease. | 2014 | Details |
| A23105 | 24038130 | Hepatology | Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis. | 2014 | Details |
| A23106 | 24038081 | Hepatology | All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade. | 2014 | Details |
| A23109 | 24035445 | Metabolism | Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and intralipid solutions and correlation to insulin levels. | 2013 | Details |
| A23110 | 24034940 | Fertil Steril | Polycystic ovary syndrome and nonalcoholic fatty liver in obese adolescents: association with metabolic risk profile. | 2013 | Details |
| A23126 | 24020820 | APMIS | Highly expressed MT-ND3 positively associated with histological severity of hepatic steatosis. | 2013 | Details |
| A23136 | 24010297 | Zhongguo Zhong Yao Za Zhi | [Investigation of a compound, compatibility of Rhodiola crenulata, Cordyceps militaris, and Rhum palmatum, on metabolic syndrome treatment. IV--Improving liver lipid accumulation]. | 2013 | Details |
| A23149 | 24004441 | Free Radic Res | Involvement of free radicals and oxidative stress in NAFLD/NASH. | 2013 | Details |
| A23153 | 24000796 | Free Radic Res | Oxysterols and redox signaling in the pathogenesis of non-alcoholic fatty liver disease. | 2013 | Details |
| A23154 | 23999488 | Biochim Biophys Acta | A theoretical study of lipid accumulation in the liver-implications for nonalcoholic fatty liver disease. | 2013 | Details |
| A23156 | 23998390 | Liver Int | Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes. | 2013 | Details |
| A23163 | 23994574 | Free Radic Biol Med | Free radical biology for medicine: learning from nonalcoholic fatty liver disease. | 2013 | Details |
| A23168 | 23988487 | Biochem Pharmacol | Bile acid receptors in non-alcoholic fatty liver disease. | 2013 | Details |
| A23170 | 23985808 | Am J Clin Nutr | Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on the severity of liver disease and of glucose and lipid dysmetabolism. | 2013 | Details |
| A23178 | 23982157 | Am J Physiol Endocrinol Metab | Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice. | 2013 | Details |
| A23183 | 23980352 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Effects of resolving method of Chinese medicine on the lipid metabolism in polycystic ovary syndrome accompanied with non-alcoholic fatty liver disease]. | 2013 | Details |
| A23186 | 23977033 | PLoS One | Association of genetic variation in adaptor protein APPL1/APPL2 loci with non-alcoholic fatty liver disease. | 2013 | Details |
| A23202 | 23964070 | Am J Physiol Endocrinol Metab | Metformin prevents liver tumorigenesis induced by high-fat diet in C57Bl/6 mice. | 2013 | Details |
| A23205 | 23960084 | Mol Endocrinol | Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD. | 2013 | Details |
| A23215 | 23951308 | PLoS One | The g0/g1 switch gene 2 is an important regulator of hepatic triglyceride metabolism. | 2013 | Details |
| A23217 | 23951220 | PLoS One | Chronic ethanol consumption disrupts the core molecular clock and diurnal rhythms of metabolic genes in the liver without affecting the suprachiasmatic nucleus. | 2013 | Details |
| A23218 | 23948064 | Biochem Pharmacol | Salsalate and adiponectin ameliorate hepatic steatosis by inhibition of the hepatokine fetuin-A. | 2013 | Details |
| A23222 | 23942585 | Eur J Nutr | Dietary walnut oil modulates liver steatosis in the obese Zucker rat. | 2013 | Details |
| A23244 | 23929732 | Hepatology | Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. | 2014 | Details |