Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A20818 | 25714671 | Am J Physiol Endocrinol Metab | Liver protein profiles in insulin receptor-knockout mice reveal novel molecules involved in the diabetes pathophysiology. | 2015 | Details |
| A20827 | 25708949 | Naunyn Schmiedebergs Arch Pharmacol | Protective effect of boswellic acids versus pioglitazone in a rat model of diet-induced non-alcoholic fatty liver disease: influence on insulin resistance and energy expenditure. | 2015 | Details |
| A20832 | 25706109 | Curr Drug Targets | Discovery of Novel Anti-Diabetic Drugs by Targeting Lipid Metabolism. | 2015 | Details |
| A20835 | 25703085 | J Hepatol | PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis. | 2015 | Details |
| A20841 | 25697114 | Med Hypotheses | Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH. | 2015 | Details |
| A20846 | 25690560 | Eur J Clin Invest | Low-normal thyroid function and the pathogenesis of common cardio-metabolic disorders. | 2015 | Details |
| A20847 | 25690422 | Nutrients | Low-normal thyroid function and novel cardiometabolic biomarkers. | 2015 | Details |
| A20851 | 25686742 | Dig Dis Sci | Prevalence of Insulin Resistance in Subjects with Nonalcoholic Fatty Liver Disease and Its Predictors in a Chinese Population. | 2015 | Details |
| A20862 | 25681381 | Clin Infect Dis | Nonalcoholic Steatohepatitis and Hepatic Fibrosis in HIV-1-Monoinfected Adults With Elevated Aminotransferase Levels on Antiretroviral Therapy. | 2015 | Details |
| A20868 | 25677815 | Digestion | Association between serum osteocalcin levels and non-alcoholic fatty liver disease in women. | 2015 | Details |
| A20870 | 25676019 | Front Med | Metformin and metabolic diseases: a focus on hepatic aspects. | 2015 | Details |
| A20875 | 25671801 | Horm Metab Res | Does metformin treatment influence bone formation in patients with nonalcoholic fatty liver disease? | 2015 | Details |
| A20876 | 25671200 | J Exerc Nutrition Biochem | Effect of aerobic exercise training on non-alcoholic fatty liver disease induced by a high fat diet in C57BL/6 mice. | 2014 | Details |
| A20879 | 25669174 | Clin Pharmacol Ther | Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis. | 2015 | Details |
| A20880 | 25668433 | PLoS Negl Trop Dis | Trypanosoma cruzi infection is a potent risk factor for non-alcoholic steatohepatitis enhancing local and systemic inflammation associated with strong oxidative stress and metabolic disorders. | 2015 | Details |
| A20885 | 25664838 | Nutr Diabetes | Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity. | 2015 | Details |
| A20890 | 25659874 | Atheroscler Suppl | The effect of ezetimibe on NAFLD. | 2015 | Details |
| A20895 | 25657751 | J Res Med Sci | The relationship between resistin and ghrelin levels with fibrosis in nonalcoholic fatty liver disease. | 2014 | Details |
| A20902 | 25654291 | Zhonghua Gan Zang Bing Za Zhi | [Impact of JNK inhibitor XG-102 in a diet-induced rat model of non-alcoholic steatohepatitis]. | 2014 | Details |
| A20906 | 25651169 | Cell Metab | Turn up the heat: circulating serotonin tunes our internal heating system. | 2015 | Details |
| A20908 | 25649191 | Obes Res Clin Pract | Elevation of branched-chain amino acid levels in diabetes and NAFL and changes with antidiabetic drug treatment. | 2015 | Details |
| A20909 | 25648740 | Eur J Nutr | Self-reported eating speed in relation to non-alcoholic fatty liver disease in adults. | 2015 | Details |
| A20915 | 25646886 | J Hepatol | Hepatic STAMP2 alleviates high fat diet-induced hepatic steatosis and insulin resistance. | 2015 | Details |
| A20916 | 25646773 | PLoS One | Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt. | 2015 | Details |
| A20918 | 25646328 | Am J Clin Nutr | Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes. | 2014 | Details |
| A20922 | 25643684 | Gac Med Mex | [Hepatic steatosis (HS) as a factor associated with the presence of metabolic risk in schoolchildren and obese adolescents]. | 2014 | Details |
| A20931 | 25633064 | Arch Dis Child | Paediatric non-alcoholic fatty liver disease: a practical overview for non-specialists. | 2015 | Details |
| A20935 | 25632188 | World J Gastroenterol | Factors associated with significant liver fibrosis assessed using transient elastography in general population. | 2015 | Details |
| A20942 | 25624996 | World J Hepatol | Adiponectin serum level in chronic hepatitis C infection and therapeutic profile. | 2015 | Details |
| A20953 | 25619540 | Curr Diabetes Rev | Is type 2 diabetes mellitus a predisposal cause for developing hepatocellular carcinoma? | 2015 | Details |
| A20957 | 25617860 | Atherosclerosis | A concise review of non-alcoholic fatty liver disease. | 2015 | Details |
| A20963 | 25617046 | Expert Rev Gastroenterol Hepatol | Effects of Mediterranean diet supplemented with silybin-vitamin E-phospholipid complex in overweight patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A20967 | 25614040 | J Spinal Cord Med | Low testosterone and non-alcoholic fatty liver disease: Evidence for their independent association in men with chronic spinal cord injury. | 2016 | Details |
| A20973 | 25609431 | FASEB J | Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH. | 2015 | Details |
| A20981 | 25604802 | Expert Opin Investig Drugs | Early investigational drugs targeting PPAR-α for the treatment of metabolic disease. | 2015 | Details |
| A20986 | 25601465 | Curr Mol Med | Understanding nutritional interventions and physical exercise in non-alcoholic fatty liver disease. | 2015 | Details |
| A20992 | 25598791 | Hepat Mon | Are women with polycystic ovarian syndrome at a high risk of non-alcoholic Fatty liver disease; a meta-analysis. | 2014 | Details |
| A20996 | 25595882 | J Hepatol | Two non-psychoactive cannabinoids reduce intracellular lipid levels and inhibit hepatosteatosis. | 2015 | Details |
| A20997 | 25593466 | World J Gastroenterol | miRNA-103: molecular link between insulin resistance and nonalcoholic fatty liver disease. | 2015 | Details |
| A21004 | 25583095 | Clin Biochem | Laboratory assessment of cardiometabolic risk in overweight and obese children. | 2015 | Details |
| A21011 | 25577467 | J Nutr Biochem | Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis. | 2014 | Details |
| A21012 | 25577300 | Dig Liver Dis | Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial. | 2014 | Details |
| A21014 | 25576095 | J Nutr Biochem | Maternal taurine supplementation attenuates maternal fructose-induced metabolic and inflammatory dysregulation and partially reverses adverse metabolic programming in offspring. | 2014 | Details |
| A21017 | 25575111 | Can J Gastroenterol Hepatol | Biomarkers in nonalcoholic fatty liver disease. | 2014 | Details |
| A21018 | 25574593 | Diabetes Technol Ther | Relationship between β-cell function, metabolic control, and microvascular complications in type 2 diabetes mellitus. | 2015 | Details |
| A21021 | 25573175 | Am J Physiol Gastrointest Liver Physiol | Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. | 2015 | Details |
| A21027 | 25566193 | Front Endocrinol (Lausanne) | O-GlcNAc: A Bittersweet Switch in Liver. | 2014 | Details |
| A21028 | 25566190 | Front Endocrinol (Lausanne) | Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice. | 2014 | Details |
| A21036 | 25563143 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease as a potential risk factor of cardiovascular disease. | 2015 | Details |
| A21037 | 25562616 | Endocrinology | Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, β-cryptoxanthin. | 2015 | Details |
| A21039 | 25562147 | Cell Physiol Biochem | Aberrant hepatic microRNA expression in nonalcoholic fatty liver disease. | 2014 | Details |
| A21049 | 25554608 | Endokrynol Pol | Non-alcoholic fatty liver disease in women with polycystic ovary syndrome - clinical and metabolic aspects and lipoprotein lipase gene polymorphism. | 2014 | Details |
| A21050 | 25553983 | Eur J Intern Med | Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease. | 2014 | Details |
| A21054 | 25550952 | Int J Clin Exp Med | Assessment of hepatic steatosis on contrast enhanced computed tomography in patients with colorectal cancer. | 2014 | Details |
| A21059 | 28596988 | J Diabetes Obes | NAFLD Susceptibility Genes and their Association with Type 2 Diabetes and Obesity in a New Mexico Population. | 2015 | Details |
| A21065 | 27417789 | Healthcare (Basel) | Fatty Liver and Fatty Heart-Where do They Stand in the AMIS Syndrome? | 2015 | Details |
| A21069 | 27188459 | Nat Rev Dis Primers | Nonalcoholic fatty liver disease. | 2015 | Details |
| A21077 | 25548489 | World J Gastroenterol | MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease. | 2014 | Details |
| A21079 | 25548472 | World J Gastroenterol | Intestinal microbiota and type 2 diabetes: from mechanism insights to therapeutic perspective. | 2014 | Details |
| A21083 | 25544875 | World J Hepatol | Involvement of the TAGE-RAGE system in non-alcoholic steatohepatitis: Novel treatment strategies. | 2014 | Details |
| A21085 | 25544409 | Rev Esp Enferm Dig | Insulin resistance and metabolic syndrome are related to non-alcoholic fatty liver disease, but not visceral adiposity index, in severely obese patients. | 2014 | Details |
| A21087 | 25543522 | Clin Res Hepatol Gastroenterol | Nonalcoholic fatty liver disease (NAFLD) without insulin resistance: Is it different? | 2014 | Details |
| A21089 | 25542756 | Eur J Pharmacol | Ameliorative effect of nicorandil on high fat diet induced non-alcoholic fatty liver disease in rats. | 2014 | Details |
| A21091 | 25541279 | Prostaglandins Leukot Essent Fatty Acids | Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. | 2014 | Details |
| A21098 | 25536650 | Ann Hepatol | Lifestyle changes associated with a new antioxidant formulation in non-alcoholic fatty liver disease: a case series. | 2015 | Details |
| A21103 | 25534988 | Biochem Pharmacol | The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet. | 2014 | Details |
| A21104 | 25534442 | Life Sci | Role of physical exercise on hepatic insulin, glucocorticoid and inflammatory signaling pathways in an animal model of non-alcoholic steatohepatitis. | 2014 | Details |
| A21108 | 25533429 | Eur J Gastroenterol Hepatol | Effects of ursodeoxycholic acid therapy on carotid intima media thickness, apolipoprotein A1, apolipoprotein B, and apolipoprotein B/A1 ratio in nonalcoholic steatohepatitis. | 2015 | Details |
| A21111 | 25533006 | Nutrients | Simple sugar intake and hepatocellular carcinoma: epidemiological and mechanistic insight. | 2014 | Details |
| A21118 | 25530013 | Nutr Res | Blood redox status is associated with the likelihood of nonalcoholic fatty liver disease irrespectively of diet's total antioxidant capacity. | 2014 | Details |
| A21125 | 25527748 | Am J Clin Nutr | Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis. | 2014 | Details |
| A21128 | 25526027 | Oncotarget | Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat. | 2014 | Details |
| A21133 | 25524401 | Hepatology | The impact of phlebotomy in nonalcoholic fatty liver disease: A prospective, randomized, controlled trial. | 2015 | Details |
| A21143 | 25516477 | Metabolism | The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy. | 2014 | Details |
| A21146 | 25514916 | Rev Recent Clin Trials | Non alcoholic fatty liver: epidemiology and natural history. | 2014 | Details |
| A21152 | 25514910 | Rev Recent Clin Trials | Common features of the metabolic syndrome and nonalcoholic fatty liver disease. | 2014 | Details |
| A21155 | 25514907 | Rev Recent Clin Trials | Insulin resistance, non-alcoholic fatty liver disease and hepatitis C virus infection. | 2014 | Details |
| A21157 | 25514415 | Int J Mol Sci | Irisin, a link among fatty liver disease, physical inactivity and insulin resistance. | 2014 | Details |
| A21161 | 25512797 | World J Diabetes | Nonalcoholic steatohepatitis and insulin resistance in children. | 2014 | Details |
| A21165 | 25509904 | Ter Arkh | [[Current approaches to diagnosing and treating nonalcoholic fatty liver disease]. | 2014 | Details |
| A21166 | 25509888 | Ter Arkh | [Adiponectin and parameters of glucose and lipid metabolism at different clinical and morphological stages of non-alcoholic fatty liver disease in patients with abdominal obesity]. | 2014 | Details |
| A21171 | 25502558 | PLoS One | A model of metabolic syndrome and related diseases with intestinal endotoxemia in rats fed a high fat and high sucrose diet. | 2014 | Details |
| A21187 | 25492998 | World J Gastroenterol | Focus on emerging drugs for the treatment of patients with non-alcoholic fatty liver disease. | 2014 | Details |
| A21188 | 25492997 | World J Gastroenterol | Alimentary regimen in non-alcoholic fatty liver disease: Mediterranean diet. | 2014 | Details |
| A21191 | 25491010 | Eur J Intern Med | The effect of fatty pancreas on serum glucose parameters in patients with nonalcoholic steatohepatitis. | 2014 | Details |
| A21196 | 25485911 | Nat Med | Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis. | 2014 | Details |
| A21197 | 25484079 | Autophagy | Calcium channel blockers as potential therapeutics for obesity-associated autophagy defects and fatty liver pathologies. | 2014 | Details |
| A21205 | 25479248 | Nutrients | The role of intestinal bacteria overgrowth in obesity-related nonalcoholic fatty liver disease. | 2014 | Details |
| A21212 | 25477509 | J Biol Chem | Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice. | 2014 | Details |
| A21217 | 25473159 | World J Gastroenterol | Gut microbiota and metabolic syndrome. | 2014 | Details |
| A21219 | 25470627 | Diabetes Metab Syndr | The value of different insulin resistance indices in assessment of non-alcoholic fatty liver disease in overweight/obese children. | 2013 | Details |
| A21229 | 25469013 | World J Gastroenterol | Obesity, fatty liver disease and intestinal microbiota. | 2014 | Details |
| A21230 | 25468829 | Int J Obes (Lond) | Fetuin-A: a novel link between obesity and related complications. | 2014 | Details |
| A21231 | 25468788 | Med Hypotheses | Pentoxifylline in the management of metabolic syndrome and chronic hepatitis C. | 2014 | Details |
| A21243 | 25459558 | Clin Gastroenterol Hepatol | Nonalcoholic fatty liver disease increases the risk of hepatocellular carcinoma in patients with alcohol-associated cirrhosis awaiting liver transplants. | 2014 | Details |
| A21245 | 25457209 | J Hepatol | Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2. | 2014 | Details |
| A21247 | 25456868 | Am J Cardiol | Relation of physical activity to prevalence of nonalcoholic Fatty liver disease independent of cardiometabolic risk. | 2014 | Details |
| A21250 | 25456097 | Metabolism | Leptin in nonalcoholic fatty liver disease: a narrative review. | 2014 | Details |
| A21255 | 25453513 | J Med Food | Green Tea Lowers Hepatic COX-2 and Prostaglandin E2 in Rats with Dietary Fat-Induced Nonalcoholic Steatohepatitis. | 2014 | Details |
| A21256 | 25452862 | BMJ Open Diabetes Res Care | Elevated 1 h postload plasma glucose levels identify adults with normal glucose tolerance but increased risk of non-alcoholic fatty liver disease. | 2014 | Details |