Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A45436 | 24597776 | J Nat Prod | Identification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gamma. | 2014 | Details |
| A45448 | 24511104 | J Lipid Res | PNPLA3 mediates hepatocyte triacylglycerol remodeling. | 2014 | Details |
| A45452 | 24490657 | BMC Complement Altern Med | Isoquercitrin activates the AMP-activated protein kinase (AMPK) signal pathway in rat H4IIE cells. | 2014 | Details |
| A45509 | 24223615 | Evid Based Complement Alternat Med | Zerumbone, a Natural Cyclic Sesquiterpene of Zingiber zerumbet Smith, Attenuates Nonalcoholic Fatty Liver Disease in Hamsters Fed on High-Fat Diet. | 2013 | Details |
| A45512 | 24222087 | Semin Liver Dis | Lipids and the liver. | 2013 | Details |
| A45528 | 24129500 | Eur J Nutr | Adiponectin receptor 1 enhances fatty acid metabolism and cell survival in palmitate-treated HepG2 cells through the PI3 K/AKT pathway. | 2013 | Details |
| A45531 | 24104204 | Physiol Genomics | Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing. | 2013 | Details |
| A45533 | 24095738 | Cell Rep | The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome. | 2013 | Details |
| A45540 | 24030551 | Arterioscler Thromb Vasc Biol | Apolipoprotein A-IV expression in mouse liver enhances triglyceride secretion and reduces hepatic lipid content by promoting very low density lipoprotein particle expansion. | 2013 | Details |
| A45545 | 23999826 | Endocr Connect | Increased FGF21 plasma levels in humans with sepsis and SIRS. | 2013 | Details |
| A45556 | 23929893 | Aging (Albany NY) | Lipid-induced hepatic insulin resistance. | 2013 | Details |
| A45562 | 23878812 | Biomed Res Int | Molecular functions of thyroid hormones and their clinical significance in liver-related diseases. | 2013 | Details |
| A45564 | 23871243 | Curr Biol | Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. | 2013 | Details |
| A45584 | 23772495 | Nihon Naika Gakkai Zasshi | [Diabetes mellitus related common medical disorders: recent progress in diagnosis and treatment. Topics: I. Pathophysiology, diagnosis and treatment; 1. Nonalcoholic fatty liver disease]. | 2013 | Details |
| A45586 | 23766126 | Endocrinology | Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice. | 2013 | Details |
| A45592 | 23731091 | J Agric Food Chem | Mulberry anthocyanins inhibit oleic acid induced lipid accumulation by reduction of lipogenesis and promotion of hepatic lipid clearance. | 2013 | Details |
| A45601 | 23712496 | Mamm Genome | High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice. | 2013 | Details |
| A45622 | 23602251 | Nutr Res | Gly482Ser mutation impairs the effects of peroxisome proliferator-activated receptor γ coactivator-1α on decreasing fat deposition and stimulating phosphoenolpyruvate carboxykinase expression in hepatocytes. | 2013 | Details |
| A45632 | 23536474 | Hepatology | Regulation of cholesterol and bile acid homeostasis by the cholesterol 7α-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice. | 2013 | Details |
| A45635 | 23510587 | Lipids Health Dis | Micronutrients-fortified rapeseed oil improves hepatic lipid accumulation and oxidative stress in rats fed a high-fat diet. | 2013 | Details |
| A45642 | 23493538 | Adv Nutr | Energy and fructose from beverages sweetened with sugar or high-fructose corn syrup pose a health risk for some people. | 2013 | Details |
| A45643 | 23486979 | J Nutr | Fatty liver accompanies an increase in lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet. | 2013 | Details |
| A45645 | 23482364 | Georgian Med News | [Role of proapoptotic p-53 factor in pathogenesis of nonalcoholic hepatosteatosis]. | 2013 | Details |
| A45647 | 23474422 | Gut | Yin Yang 1 and farnesoid X receptor: a balancing act in non-alcoholic fatty liver disease? | 2013 | Details |
| A45649 | 23467323 | Am J Physiol Regul Integr Comp Physiol | Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats. | 2013 | Details |
| A45652 | 23447428 | Hepatology | Adiponectin, bile acids, and burnt-out nonalcoholic steatohepatitis: new light on an old paradox. | 2013 | Details |
| A45657 | 23423574 | Diabetes | Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance. | 2013 | Details |
| A45658 | 23409094 | PLoS One | Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice. | 2013 | Details |
| A45662 | 23401290 | Hepatology | Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease. | 2013 | Details |
| A45666 | 23374710 | Vitam Horm | Hormonal regulation of lipogenesis. | 2013 | Details |
| A45678 | 23305377 | Curr Vasc Pharmacol | Editorial: Exploring Lipid-related Treatment Options for the Treatment of NASH. | 2014 | Details |
| A45706 | 23175343 | Postepy Hig Med Dosw (Online) | [Role of sphingolipids in digestive system]. | 2012 | Details |
| A45713 | 23144998 | PLoS One | Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids. | 2012 | Details |
| A45715 | 23127162 | Metab Syndr Relat Disord | The evolving scenario of copper and fatty liver. | 2012 | Details |
| A45726 | 23053554 | Am J Clin Nutr | Mitigating factors and metabolic mechanisms in fructose-induced nonalcoholic fatty liver disease: the next challenge. | 2012 | Details |
| A45727 | 23047983 | Am J Physiol Endocrinol Metab | Maternal androgen excess reduces placental and fetal weights, increases placental steroidogenesis, and leads to long-term health effects in their female offspring. | 2012 | Details |
| A45763 | 22877991 | Biochim Biophys Acta | Physiological roles of phosphatidylethanolamine N-methyltransferase. | 2012 | Details |
| A45769 | 22855658 | Case Rep Gastroenterol | Familial hypobetalipoproteinemia-induced nonalcoholic steatohepatitis. | 2012 | Details |
| A45774 | 22814966 | Hepatology | Glycogen synthase kinase 3-mediated voltage-dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation. | 2013 | Details |
| A45813 | 22612529 | J Vet Pharmacol Ther | Pharmacokinetics of pioglitazone in lean and obese cats. | 2012 | Details |
| A45815 | 22592130 | Metabolism | Sulfated oxysterol 25HC3S as a therapeutic target of non-alcoholic fatty liver disease. | 2012 | Details |
| A45817 | 22560205 | Cell Metab | Cell Metabolism 2012 focus on lipids and insulin resistance. | 2012 | Details |
| A45832 | 22484034 | Biochim Biophys Acta | PFOS-induced hepatic steatosis, the mechanistic actions on β-oxidation and lipid transport. | 2012 | Details |
| A45839 | 22441585 | MAGMA | Hepatic lipid composition differs between ob/ob and ob/+ control mice as determined by using in vivo localized proton magnetic resonance spectroscopy. | 2012 | Details |
| A45852 | 22386938 | Metabolism | Sulfated oxysterols as candidates for the treatment of nonalcoholic fatty liver disease. | 2012 | Details |
| A45864 | 22311368 | Dig Dis Sci | Mechanisms linking nonalcoholic fatty liver disease with coronary artery disease. | 2012 | Details |
| A45875 | 22243683 | Lipids Health Dis | Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells. | 2012 | Details |
| A45880 | 22225954 | Metabolism | Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease. | 2012 | Details |
| A45890 | 22187655 | J Lipids | Nuclear receptors in nonalcoholic Fatty liver disease. | 2011 | Details |
| A45897 | 22154323 | Metabolism | Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice. | 2011 | Details |
| A45915 | 22101559 | Curr Opin Lipidol | Current world literature. | 2011 | Details |
| A45927 | 22027575 | J Hepatol | Hepatitis B virus infection and fatty liver in the general population. | 2011 | Details |
| A45930 | 21997755 | Dig Dis Sci | The effect of taurine on hepatic steatosis induced by thioacetamide in zebrafish (Danio rerio). | 2011 | Details |
| A45951 | 21893033 | Biochem Biophys Res Commun | Regular exercise prevents high-sucrose diet-induced fatty liver via improvement of hepatic lipid metabolism. | 2011 | Details |
| A45960 | 21841000 | J Biol Chem | L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin. | 2011 | Details |
| A46026 | 21494141 | Curr Opin Lipidol | Hepatic fatty acid partitioning. | 2011 | Details |
| A46032 | 21476910 | Expert Rev Gastroenterol Hepatol | Relevance of TNF-α gene polymorphisms in nonalcoholic fatty liver disease. | 2011 | Details |
| A46035 | 21476906 | Expert Rev Gastroenterol Hepatol | Perspectives on cellular dysfunction in nonalcoholic steatohepatitis: a case of 'multiorganelle failure'? Proceedings of a virtual workshop on nonalcoholic steatohepatitis. | 2011 | Details |
| A46038 | 21465511 | Hepatology | Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. | 2011 | Details |
| A46068 | 21300117 | J Hepatol | Effect of treatment with polyunsaturated fatty acids on HCV- or diet-induced fatty liver. | 2011 | Details |
| A46083 | 21206342 | Curr Opin Lipidol | Nutrition and metabolism: nutritional therapy for disordered triglyceride metabolism and nonalcoholic fatty liver disease. | 2010 | Details |
| A46096 | 21123947 | J Clin Invest | Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver. | 2010 | Details |
| A46102 | 21094870 | Transplant Proc | Living donor liver transplantation for Dorfman-Chanarin syndrome with 1 year follow-up: case report. | 2010 | Details |
| A46105 | 21084450 | Endocrinology | GH-dependent STAT5 signaling plays an important role in hepatic lipid metabolism. | 2010 | Details |
| A46120 | 20960377 | Semin Liver Dis | The role of lipid metabolism in the pathogenesis of alcoholic and nonalcoholic hepatic steatosis. | 2010 | Details |
| A46122 | 20919931 | Antioxid Redox Signal | Chronic exposure to a high-fat diet induces hepatic steatosis, impairs nitric oxide bioavailability, and modifies the mitochondrial proteome in mice. | 2011 | Details |
| A46130 | 20860563 | Liver Int | Cross-regulation of cannabinoid CB₁ and CB₂ receptors governs hepatic steatosis. | 2010 | Details |
| A46139 | 20807839 | Am J Physiol Endocrinol Metab | A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain. | 2010 | Details |
| A46149 | 20717042 | J Clin Gastroenterol | The potential adverse role of leptin resistance in nonalcoholic fatty liver disease: a hypothesis based on critical review of the literature. | 2011 | Details |
| A46165 | 20639500 | J Biomol Screen | Identification of MicroRNAs that control lipid droplet formation and growth in hepatocytes via high-content screening. | 2010 | Details |
| A46174 | 20581678 | Curr Opin Lipidol | Recent insights into fatty liver, metabolic dyslipidaemia and their links to insulin resistance. | 2010 | Details |
| A46179 | 20530735 | Am J Physiol Endocrinol Metab | FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase. | 2010 | Details |
| A46215 | 20232488 | Hepatology | Natural approach against lipotoxic traffic in nonalcoholic fatty liver disease. | 2010 | Details |
| A46221 | 20211973 | Endocrinology | Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet. | 2010 | Details |
| A46240 | 20103702 | Diabetes | C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis. | 2010 | Details |
| A46244 | 20060143 | Metabolism | Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model. | 2010 | Details |
| A46276 | 19838201 | Nat Med | Foxo1 integrates insulin signaling with mitochondrial function in the liver. | 2009 | Details |
| A46304 | 19637289 | Hepatology | Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. | 2009 | Details |
| A46307 | 19609336 | Rev Gastroenterol Peru | [Don't forget nonalcoholic fatty liver disease in patients with HIV infection]. | 2009 | Details |
| A46313 | 19572984 | Alcohol Clin Exp Res | MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice. | 2009 | Details |
| A46336 | 19463838 | Toxicol Appl Pharmacol | Gel entrapment culture of rat hepatocytes for investigation of tetracycline-induced toxicity. | 2009 | Details |
| A46343 | 19426389 | J Dig Dis | Bile acids and insulin resistance: implications for treating nonalcoholic fatty liver disease. | 2009 | Details |
| A46345 | 19403641 | Am J Clin Nutr | Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes. | 2009 | Details |
| A46348 | 19387919 | Semin Liver Dis | Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. | 2009 | Details |
| A46364 | 19296690 | Anal Chem | In situ lipidomic analysis of nonalcoholic fatty liver by cluster TOF-SIMS imaging. | 2009 | Details |
| A46388 | 19116372 | Am J Physiol Endocrinol Metab | The genetics of neutral lipid biosynthesis: an evolutionary perspective. | 2008 | Details |
| A46390 | 19105205 | Hepatology | Ethnic differences in hepatic steatosis: an insulin resistance paradox? | 2009 | Details |
| A46425 | 18772330 | Am J Pathol | Prevention of hepatic fibrosis in a murine model of metabolic syndrome with nonalcoholic steatohepatitis. | 2008 | Details |
| A46431 | 18698578 | Hepatology | Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury. | 2008 | Details |
| A46435 | 18673132 | Mini Rev Med Chem | Which treatment for nonalcoholic fatty liver disease? | 2008 | Details |
| A46474 | 18393289 | Hepatology | Noninvasive assessment of hepatic lipid composition: Advancing understanding and management of fatty liver disorders. | 2008 | Details |
| A46482 | 18367000 | Curr Diab Rep | Fatty liver, insulin resistance, and dyslipidemia. | 2008 | Details |
| A46512 | 18161723 | Hepatology | Nonalcoholic fatty liver disease (NAFLD) and cardiac lipotoxicity: Another piece of the puzzle. | 2008 | Details |
| A46575 | 17498512 | Gastroenterology | Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease. | 2007 | Details |
| A46608 | 17318260 | J Clin Invest | Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. | 2007 | Details |
| A46648 | 16912127 | J Clin Endocrinol Metab | Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat. | 2006 | Details |
| A46651 | 16847302 | Ann Intern Med | A rare cause of nonalcoholic fatty liver disease. | 2006 | Details |
| A46678 | 16618425 | Gastroenterology | Ins and outs modulating hepatic triglyceride and development of nonalcoholic fatty liver disease. | 2006 | Details |
| A46722 | 16220049 | Curr Opin Gastroenterol | Role of inflammation in nonalcoholic steatohepatitis. | 2005 | Details |
| A46762 | 15779390 | Nihon Rinsho | [Impaired glucose tolerance in nonalcoholic fatty liver disease]. | 2005 | Details |