Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A14171 | 29553485 | J Clin Invest | Aortic carboxypeptidase-like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis. | 2018 | Details |
| A14176 | 29550812 | Cell Physiol Biochem | Lack of ClC-2 Alleviates High Fat Diet-Induced Insulin Resistance and Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A14180 | 29548345 | BMC Pharmacol Toxicol | A randomised, double-blind, placebo-controlled phase 1 study of the safety, tolerability and pharmacodynamics of volixibat in overweight and obese but otherwise healthy adults: implications for treatment of non-alcoholic steatohepatitis. | 2018 | Details |
| A14181 | 29547708 | Atherosclerosis | Resolution of fatty liver and weight loss: Independent associations with changes in serum lipids and apolipoproteins. | 2018 | Details |
| A14183 | 29547047 | Endocr Pract | PEDIATRIC VISCERAL ADIPOSITY INDEX ADAPTATION CORRELATES WITH HOMA-IR, MATSUDA, AND TRANSAMINASES. | 2018 | Details |
| A14188 | 29540533 | Biosci Rep | Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD. | 2018 | Details |
| A14190 | 29538359 | Pediatr Res | Gut microbiota in adolescents and the association with fatty liver: the EPOCH study. | 2018 | Details |
| A14191 | 29537411 | J R Coll Physicians Edinb | Bariatric surgery as a treatment for metabolic syndrome. | 2017 | Details |
| A14201 | 29527789 | Diabetes Obes Metab | Use of a metabolomic approach to non-invasively diagnose non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus. | 2018 | Details |
| A14205 | 29527140 | Clin Proteomics | Proteomic characterization of high-density lipoprotein particles in patients with non-alcoholic fatty liver disease. | 2018 | Details |
| A14206 | 29526820 | Biochim Biophys Acta Mol Basis Dis | Benzbromarone aggravates hepatic steatosis in obese individuals. | 2018 | Details |
| A14207 | 29526751 | Biochem Biophys Res Commun | Enoyl coenzyme A hydratase 1 protects against high-fat-diet-induced hepatic steatosis and insulin resistance. | 2018 | Details |
| A14211 | 29524401 | Biochem Biophys Res Commun | Ablation of prolactin receptor increases hepatic triglyceride accumulation. | 2018 | Details |
| A14212 | 29523931 | Arch Toxicol | In utero and lactational exposure to BDE-47 promotes obesity development in mouse offspring fed a high-fat diet: impaired lipid metabolism and intestinal dysbiosis. | 2018 | Details |
| A14218 | 29519663 | Surg Obes Relat Dis | Patients with clinically metabolically healthy obesity are not necessarily healthy subclinically: further support for bariatric surgery in patients without metabolic disease? | 2017 | Details |
| A14222 | 29517842 | Liver Int | Serum testosterone and non-alcoholic fatty liver disease in men and women in the US. | 2018 | Details |
| A14223 | 29517271 | Biomark Med | The search for noninvasive methods to identify liver fibrosis in children with nonalcoholic fatty liver disease. | 2018 | Details |
| A14224 | 29516496 | J Physiol | Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation. | 2018 | Details |
| A14226 | 29515630 | Iran J Pathol | Clinical Manifestations and Diagnosis of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14230 | 29514047 | Biochim Biophys Acta Mol Basis Dis | Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome. | 2018 | Details |
| A14235 | 29511882 | Curr Atheroscler Rep | Cardiometabolic Effects of Anti-obesity Pharmacotherapy. | 2018 | Details |
| A14238 | 29510489 | Int J Mol Sci | Divergent Role of Sphingosine 1-Phosphate in Liver Health and Disease. | 2018 | Details |
| A14241 | 29508520 | Mol Nutr Food Res | Sugary Kefir Strain Lactobacillus mali APS1 Ameliorated Hepatic Steatosis by Regulation of SIRT-1/Nrf-2 and Gut Microbiota in Rats. | 2018 | Details |
| A14242 | 29508519 | Mol Nutr Food Res | Caffeic Acid Phenethyl Ester Improves Metabolic Syndrome by Activating PPAR-γ and Inducing Adipose Tissue Remodeling in Diet-Induced Obese Mice. | 2018 | Details |
| A14247 | 29507217 | Proc Natl Acad Sci U S A | High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism. | 2018 | Details |
| A14248 | 29507043 | J Endocrinol | Lactobacillus acidophilus NS1 attenuates diet-induced obesity and fatty liver. | 2018 | Details |
| A14253 | 29504312 | J Zhejiang Univ Sci B | Role of exosome-associated microRNA in diagnostic and therapeutic applications to metabolic disorders. | 2018 | Details |
| A14258 | 29499974 | Trends Pharmacol Sci | Specialized Proresolving Mediators: Enhancing Nonalcoholic Steatohepatitis and Fibrosis Resolution. | 2018 | Details |
| A14260 | 29498345 | Br J Nutr | 20-Week follow-up of hepatic steatosis installation and liver mitochondrial structure and activity and their interrelation in rats fed a high-fat-high-fructose diet. | 2018 | Details |
| A14263 | 29496501 | Am J Med | Geographic Variability in Liver Disease-Related Mortality Rates in the United States. | 2018 | Details |
| A14265 | 29494209 | Am J Physiol Gastrointest Liver Physiol | Biliverdin reductase and bilirubin in hepatic disease. | 2018 | Details |
| A14270 | 29491146 | J Biol Chem | Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease. | 2018 | Details |
| A14274 | 29488485 | Ter Arkh | [Nonalcoholic fatty liver disease without obesity: the problem to be solved]. | 2019 | Details |
| A14277 | 29487137 | Genetics | Seven-Up Is a Novel Regulator of Insulin Signaling. | 2018 | Details |
| A14278 | 29486327 | Biochim Biophys Acta Mol Cell Biol Lipids | FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells. | 2018 | Details |
| A14280 | 29485130 | Am J Gastroenterol | The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth. | 2018 | Details |
| A14285 | 29483369 | Biosci Rep | Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring. | 2018 | Details |
| A14286 | 29482963 | Nutr Metab Cardiovasc Dis | Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: A prospective pilot study. | 2017 | Details |
| A14287 | 29482933 | Acta Histochem | Deletion of Thioredoxin-interacting protein ameliorates high fat diet-induced non-alcoholic steatohepatitis through modulation of Toll-like receptor 2-NLRP3-inflammasome axis: Histological and immunohistochemical study. | 2018 | Details |
| A14288 | 29482168 | Redox Biol | Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver. | 2018 | Details |
| A14293 | 29479443 | Gastroenterol Rep (Oxf) | Effects of lifestyle modification on liver enzyme and Fibroscan in Indian patients with non-alcoholic fatty liver disease. | 2017 | Details |
| A14308 | 29471561 | Semin Liver Dis | Nonalcoholic Fatty Liver Disease in Children. | 2018 | Details |
| A14309 | 29471012 | J Hepatol | Paediatric fatty liver disease (PeFLD): All is not NAFLD - Pathophysiological insights and approach to management. | 2018 | Details |
| A14311 | 29470354 | Transplantation | Poor Survival After Retransplantation in NASH Cirrhosis. | 2019 | Details |
| A14312 | 29470286 | J Pediatr Gastroenterol Nutr | Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A14323 | 29466466 | PLoS One | Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach. | 2018 | Details |
| A14327 | 29463916 | Int J Obes (Lond) | Evaluating feasibility and accuracy of non-invasive tests for nonalcoholic fatty liver disease in severe and morbid obesity. | 2018 | Details |
| A14334 | 29462566 | Am J Physiol Endocrinol Metab | Nonalcoholic fatty liver disease and gastric bypass surgery regulate serum and hepatic levels of pyruvate kinase isoenzyme M2. | 2018 | Details |
| A14344 | 29454969 | Biochem Biophys Res Commun | JIP3 knockout protects mice against high fat diet-induced liver injury. | 2018 | Details |
| A14350 | 29452268 | Clin Gastroenterol Hepatol | High Prevalence of Liver Fibrosis Among European Adults With Unknown Liver Disease: A Population-Based Study. | 2018 | Details |
| A14352 | 29452135 | Prog Cardiovasc Dis | Evidence-Based Exercise Recommendations to Reduce Hepatic Fat Content in Youth- a Systematic Review and Meta-Analysis. | 2018 | Details |
| A14356 | 29450671 | Inflammopharmacology | Short-term treatment with metformin reduces hepatic lipid accumulation but induces liver inflammation in obese mice. | 2018 | Details |
| A14357 | 29450605 | Abdom Radiol (NY) | Abbreviated mpMRI protocol for diffuse liver disease: a practical approach for evaluation and follow-up of NAFLD. | 2018 | Details |
| A14361 | 29447962 | Int J Biol Macromol | Low molecular weight fucoidan attenuates liver injury via SIRT1/AMPK/PGC1α axis in db/db mice. | 2018 | Details |
| A14371 | 29441342 | Can J Gastroenterol Hepatol | Outcomes following Serial Intragastric Balloon Therapy for Obesity and Nonalcoholic Fatty Liver Disease in a Single Centre. | 2017 | Details |
| A14374 | 29439143 | Biosci Rep | Anarchy in the UPR: A Ca2+-insensitive PKC inhibits SERCA activity to promote ER stress. | 2018 | Details |
| A14376 | 29438686 | J Pediatr (Rio J) | Evaluation of nonalcoholic fatty liver disease using magnetic resonance in obese children and adolescents. | 2018 | Details |
| A14379 | 29437870 | Gut | CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity. | 2018 | Details |
| A14380 | 29437160 | Int J Obes (Lond) | Protective effect of black relative to white race against non-alcoholic fatty liver disease in patients with severe obesity, independent of type 2 diabetes. | 2017 | Details |
| A14385 | 29432786 | Biochimie | Oleic acid induces the novel apolipoprotein O and reduces mitochondrial membrane potential in chicken and human hepatoma cells. | 2018 | Details |
| A14387 | 29432207 | J Pediatr Endocrinol Metab | Prevalence of comorbid conditions pre-existing and diagnosed at a tertiary care pediatric weight management clinic. | 2018 | Details |
| A14396 | 29428103 | Hepatobiliary Pancreat Dis Int | Risk factors and metabolic abnormality of patients with non-alcoholic fatty liver disease: Either non-obese or obese Chinese population. | 2018 | Details |
| A14407 | 29425212 | PLoS One | Insulin resistance in lean and overweight non-diabetic Caucasian adults: Study of its relationship with liver triglyceride content, waist circumference and BMI. | 2018 | Details |
| A14411 | 29420066 | Am J Physiol Gastrointest Liver Physiol | CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease. | 2018 | Details |
| A14412 | 29419789 | Nutrients | Aged Oolong Tea Reduces High-Fat Diet-Induced Fat Accumulation and Dyslipidemia by Regulating the AMPK/ACC Signaling Pathway. | 2018 | Details |
| A14415 | 29417009 | J Family Med Prim Care | Hepatobiliary dysfunction in Type-2 diabetes mellitus. | 2022 | Details |
| A14418 | 29415050 | PLoS One | Associations of hyperuricemia and obesity with remission of nonalcoholic fatty liver disease among Chinese men: A retrospective cohort study. | 2018 | Details |
| A14422 | 29414249 | Annu Rev Pathol | Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A14425 | 29412830 | Peptides | Glucagon receptor signaling in metabolic diseases. | 2018 | Details |
| A14426 | 29411334 | J Cell Commun Signal | Regulation and bioactivity of the CCN family of genes and proteins in obesity and diabetes. | 2018 | Details |
| A14428 | 29411128 | Eur J Appl Physiol | Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease. | 2018 | Details |
| A14432 | 29409538 | BMC Res Notes | Laboratory parameters in lean NAFLD: comparison of subjects with lean NAFLD with obese subjects without hepatic steatosis. | 2018 | Details |
| A14435 | 29408694 | J Hepatol | Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. | 2018 | Details |
| A14436 | 29408602 | Mol Cell Endocrinol | Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice. | 2018 | Details |
| A14438 | 29406832 | Can J Physiol Pharmacol | Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates nonalcoholic fatty liver disease. | 2018 | Details |
| A14441 | 29405466 | J Gastroenterol Hepatol | Prediction of carotid intima-media thickness in obese patients with low prevalence of comorbidities by serum copper bioavailability. | 2018 | Details |
| A14444 | 29404514 | Hepatol Commun | Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice. | 2017 | Details |
| A14453 | 29404440 | Hepatol Commun | Engineered FGF19 eliminates bile acid toxicity and lipotoxicity leading to resolution of steatohepatitis and fibrosis in mice. | 2017 | Details |
| A14457 | 29402657 | Diabetes Metab Syndr | Nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus and its association with cardiovascular disease. | 2018 | Details |
| A14469 | 29398867 | World J Gastroenterol | Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice. | 2018 | Details |
| A14471 | 29398414 | Dig Liver Dis | Nonalcoholic fatty liver disease as a sentinel marker for the development of diabetes mellitus in non-obese subjects. | 2017 | Details |
| A14482 | 29391015 | Environ Health | Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010. | 2018 | Details |
| A14490 | 29385682 | Nutrients | Serum Antioxidant Associations with Metabolic Characteristics in Metabolically Healthy and Unhealthy Adolescents with Severe Obesity: An Observational Study. | 2018 | Details |
| A14492 | 29385034 | Nutrients | Liver Fat Scores Moderately Reflect Interventional Changes in Liver Fat Content by a Low-Fat Diet but Not by a Low-Carb Diet. | 2018 | Details |
| A14493 | 29384795 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina. | 2018 | Details |
| A14495 | 29381809 | Hepatology | Tumor Progression Locus 2 in Hepatocytes Potentiates Both Liver and Systemic Metabolic Disorders in Mice. | 2018 | Details |
| A14498 | 29380318 | Methods Mol Biol | Assessment of Fatty Liver in Models of Disease Programming. | 2018 | Details |
| A14502 | 29379536 | Arch Med Sci | Bifidobacteria and lactobacilli in the gut microbiome of children with non-alcoholic fatty liver disease: which strains act as health players? | 2016 | Details |
| A14508 | 29377201 | Ann N Y Acad Sci | Cardiometabolic risk in obese children. | 2018 | Details |
| A14509 | 29376983 | Zh Nevrol Psikhiatr Im S S Korsakova | [Antiinflammatory treatment in patients with chronic back pain]. | 2019 | Details |
| A14510 | 29376471 | Adipocyte | Emerging roles of SGLT2 inhibitors in obesity and insulin resistance: Focus on fat browning and macrophage polarization. | 2018 | Details |
| A14512 | 29375205 | World J Gastroenterol | INT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis. | 2018 | Details |
| A14513 | 29375204 | World J Gastroenterol | Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis. | 2018 | Details |
| A14514 | 29373238 | Dig Liver Dis | Effect of longitudinal changes of body fat on the incidence and regression of nonalcoholic fatty liver disease. | 2017 | Details |
| A14516 | 29373070 | J Med Food | Lipolysis-Stimulating Peptide from Soybean Protects Against High Fat Diet-Induced Apoptosis in Skeletal Muscles. | 2018 | Details |
| A14520 | 29371773 | Indian J Clin Biochem | The Effects of Onion Consumption on Prevention of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14525 | 29367725 | Sci Rep | Omentectomy Prevents Metabolic Syndrome By Reducing Appetite and Body Weight In A Diet-Induced Obesity Rat Model. | 2018 | Details |
| A14527 | 29367486 | J Oleo Sci | Improvement of Diet-induced Obesity by Ingestion of Mushroom Chitosan Prepared from Flammulina velutipes. | 2018 | Details |
| A14533 | 29366420 | Curr Pediatr Rev | Predictors of Non-Alcoholic Liver Disease in Ethnically Diverse Overweight Children and Adolescents. | 2018 | Details |
| A14534 | 29364302 | Food Funct | Effects of a combined intervention with a lentil protein hydrolysate and a mixed training protocol on the lipid metabolism and hepatic markers of NAFLD in Zucker rats. | 2018 | Details |