Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02665 | 34292604 | Hepatology | Salidroside Activates the AMP-Activated Protein Kinase Pathway to Suppress Nonalcoholic Steatohepatitis in Mice. | 2021 | Details |
| A02667 | 34292171 | Eur J Endocrinol | A recurrent familial partial lipodystrophy due to a monoallelic or biallelic LMNA founder variant highlights the multifaceted cardiac manifestations of metabolic laminopathies. | 2021 | Details |
| A02676 | 34289181 | J Gastroenterol Hepatol | Circulating tumor necrosis factor-α levels in non-alcoholic fatty liver disease: A systematic review and a meta-analysis. | 2021 | Details |
| A02677 | 34289064 | J Clin Endocrinol Metab | Hepatic Fat in Early Childhood Is Independently Associated With Estimated Insulin Resistance: The Healthy Start Study. | 2021 | Details |
| A02684 | 34284789 | Nutr Metab (Lond) | Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice. | 2021 | Details |
| A02692 | 34280515 | Adv Drug Deliv Rev | Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis. | 2021 | Details |
| A02699 | 34278728 | Physiol Rep | Lean non-alcoholic fatty liver disease and associated metabolic disturbance: A Saudi Arabian cross-sectional study. | 2021 | Details |
| A02703 | 34277974 | Endocrinol Diabetes Metab | Impact of lifestyle Intervention on branched-chain amino acid catabolism and insulin sensitivity in adolescents with obesity. | 2021 | Details |
| A02708 | 34277236 | Cureus | The Significance of the Mediterranean Diet in the Management of Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2021 | Details |
| A02711 | 34276221 | Diabetes Metab Syndr Obes | Biochanin A Regulates Cholesterol Metabolism Further Delays the Progression of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02714 | 34276153 | J Clin Exp Hepatol | Screening of Family Members of Nonalcoholic Fatty Liver Disease Patients can Detect Undiagnosed Nonalcoholic Fatty Liver Disease Among Them: Is There a Genetic Link? | 2020 | Details |
| A02719 | 34274649 | Environ Pollut | Comparative effects of genistein and bisphenol A on non-alcoholic fatty liver disease in laying hens. | 2021 | Details |
| A02724 | 34273192 | J Gastroenterol Hepatol | Insulin-like growth factor binding protein 1 ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease. | 2021 | Details |
| A02750 | 34260600 | PLoS One | Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease. | 2021 | Details |
| A02751 | 34260003 | Neurochem Res | Resveratrol Protects SH-SY5Y Cells Against Oleic Acid-Induced Glucolipid Metabolic Dysfunction and Cell Injuries Via the Wnt/β-Catenin Signalling Pathway. | 2021 | Details |
| A02756 | 34257817 | Oxid Med Cell Longev | The Therapeutic Effects and Mechanisms of Quercetin on Metabolic Diseases: Pharmacological Data and Clinical Evidence. | 2021 | Details |
| A02757 | 34257694 | Evid Based Complement Alternat Med | Alleviative Effect of Ruellia tuberosa L. on Insulin Resistance and Abnormal Lipid Accumulation in TNF-α-Treated FL83B Mouse Hepatocytes. | 2021 | Details |
| A02758 | 34257427 | Nat Rev Gastroenterol Hepatol | Dietary carbohydrates and fats in nonalcoholic fatty liver disease. | 2021 | Details |
| A02761 | 34255575 | Metab Syndr Relat Disord | Relationship Between Protein Intake and Sarcopenia in the Elderly with Nonalcoholic Fatty Liver Disease Based on the Fourth and Fifth Korea National Health and Nutrition Examination Survey. | 2021 | Details |
| A02766 | 34251802 | J Agric Food Chem | Oleanolic Acid Targets the Gut-Liver Axis to Alleviate Metabolic Disorders and Hepatic Steatosis. | 2021 | Details |
| A02776 | 34246549 | Hepatobiliary Pancreat Dis Int | The pathologic relevance of metabolic criteria in patients with biopsy-proven nonalcoholic fatty liver disease and metabolic dysfunction associated fatty liver disease: A multicenter cross-sectional study in China. | 2021 | Details |
| A02788 | 34239714 | Oman Med J | Effect of SGLT-2 Inhibitors on Non-alcoholic Fatty Liver Disease among Patients with Type 2 Diabetes Mellitus: Systematic Review with Meta-analysis and Trial Sequential Analysis of Randomized Clinical Trials. | 2021 | Details |
| A02805 | 34234198 | Sci Rep | Utility of Fibroscan XL to assess the severity of non-alcoholic fatty liver disease in patients undergoing bariatric surgery. | 2021 | Details |
| A02831 | 34226120 | Nutr Metab Cardiovasc Dis | Insulin resistance and NAFLD may influence memory performance in obese patients with prediabetes or newly-diagnosed type 2 diabetes. | 2021 | Details |
| A02848 | 34220701 | Front Endocrinol (Lausanne) | Effect of SGLT2 Inhibitors on Type 2 Diabetes Mellitus With Non-Alcoholic Fatty Liver Disease: A Meta-Analysis of Randomized Controlled Trials. | 2021 | Details |
| A02850 | 34219361 | Liver Int | PPAR-γ-induced changes in visceral fat and adiponectin levels are associated with improvement of steatohepatitis in patients with NASH. | 2021 | Details |
| A02857 | 34214406 | Expert Opin Investig Drugs | Anti-diabetic drugs and NASH: from current options to promising perspectives. | 2021 | Details |
| A02861 | 34213749 | Indian J Gastroenterol | Comparison of clinical and metabolic profiles of lean versus non-lean nonalcoholic fatty liver disease. | 2021 | Details |
| A02870 | 34211180 | Nat Metab | Intestinal MYC modulates obesity-related metabolic dysfunction. | 2021 | Details |
| A02872 | 34211098 | Commun Biol | Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance. | 2021 | Details |
| A02882 | 34206460 | Int J Mol Sci | Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice. | 2021 | Details |
| A02883 | 34206404 | Int J Mol Sci | Endothelial Progenitor Cells Dysfunctions and Cardiometabolic Disorders: From Mechanisms to Therapeutic Approaches. | 2021 | Details |
| A02886 | 34205674 | Int J Mol Sci | The Evolving Role of Fetuin-A in Nonalcoholic Fatty Liver Disease: An Overview from Liver to the Heart. | 2021 | Details |
| A02893 | 34204225 | Entropy (Basel) | Assessment of Classification Models and Relevant Features on Nonalcoholic Steatohepatitis Using Random Forest. | 2021 | Details |
| A02895 | 34203484 | Int J Mol Sci | Fructose and the Liver. | 2021 | Details |
| A02896 | 34203342 | Metabolites | Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02899 | 34202667 | Biomolecules | The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A02906 | 34201382 | Nutrients | Beyond the Paradigm of Weight Loss in Non-Alcoholic Fatty Liver Disease: From Pathophysiology to Novel Dietary Approaches. | 2021 | Details |
| A02915 | 34199317 | Int J Mol Sci | Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH. | 2021 | Details |
| A02918 | 34199237 | Diagnostics (Basel) | Three Different Genetic Risk Scores Based on Fatty Liver Index, Magnetic Resonance Imaging and Lipidomic for a Nutrigenetic Personalized Management of NAFLD: The Fatty Liver in Obesity Study. | 2021 | Details |
| A02931 | 34192792 | Horm Metab Res | Hepatic-Metabolite-Based Intermittent Fasting Enables a Sustained Reduction in Insulin Resistance in Type 2 Diabetes and Metabolic Syndrome. | 2021 | Details |
| A02933 | 34192533 | Cell Rep | Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release. | 2021 | Details |
| A02934 | 34192532 | Cell Rep | A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity. | 2021 | Details |
| A02940 | 34190318 | J Clin Endocrinol Metab | Intact Fasting Insulin Identifies Nonalcoholic Fatty Liver Disease in Patients Without Diabetes. | 2021 | Details |
| A02946 | 34188506 | Diabetes Metab Syndr Obes | Association Between the Triglyceride-Glucose Index and Outcomes of Nonalcoholic Fatty Liver Disease: A Large-Scale Health Management Cohort Study. | 2021 | Details |
| A02955 | 34185201 | Inflammopharmacology | Molecular and pathobiological involvement of fetuin-A in the pathogenesis of NAFLD. | 2021 | Details |
| A02959 | 34184286 | J Food Biochem | Buchholzia coriacea seed (wonderful kolanut) alleviates insulin resistance, steatosis, inflammation and oxidative stress in high fat diet model of fatty liver disease. | 2021 | Details |
| A02960 | 34183740 | Sci Rep | Circulating branch chain amino acids and improvement in liver fat content in response to exercise interventions in NAFLD. | 2021 | Details |
| A02964 | 34183247 | J Diabetes Complications | Non-invasive diagnosis of nonalcoholic fatty liver disease in patients with type 2 diabetes. | 2021 | Details |
| A02983 | 34174062 | J Gastrointestin Liver Dis | The Leu72Met (rs696217 G>T) Polymorphism of the Ghrelin Gene Might Be a Protective Factor for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02992 | 34171492 | Pharmacol Res | Hepatic stellate cells role in the course of metabolic disorders development - A molecular overview. | 2021 | Details |
| A02995 | 34171397 | J Ethnopharmacol | Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway. | 2021 | Details |
| A03002 | 34168429 | Drug Des Devel Ther | Metformin in Combination with Malvidin Prevents Progression of Non-Alcoholic Fatty Liver Disease via Improving Lipid and Glucose Metabolisms, and Inhibiting Inflammation in Type 2 Diabetes Rats. | 2021 | Details |
| A03013 | 34164242 | Cureus | Role of Glucagon-Like Peptide-1 Receptor Agonists in the Management of Non-Alcoholic Steatohepatitis: A Clinical Review Article. | 2021 | Details |
| A03019 | 34161185 | Autophagy | Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective. | 2021 | Details |
| A03025 | 34159710 | Int J Clin Pract | Serum neuregulin 4 (NRG-4) level and non-alcoholic fatty liver disease (NAFLD): A case-control study. | 2021 | Details |
| A03040 | 34155798 | Liver Int | Non-alcoholic fatty liver disease in type 2 diabetes - A specific entity? | 2021 | Details |
| A03056 | 34152053 | J Sleep Res | Metabolic dysfunction in OSA: Is there something new under the sun? | 2021 | Details |
| A03060 | 34149286 | Clin Exp Gastroenterol | Does Nonalcoholic Pancreatic Steatosis Always Correlate with Nonalcoholic Fatty Liver Disease? | 2021 | Details |
| A03063 | 34147036 | Semin Liver Dis | Effects of Mediterranean Diet in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Randomized Controlled Trials. | 2021 | Details |
| A03067 | 34144391 | Redox Biol | Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules. | 2021 | Details |
| A03070 | 34142516 | J Pediatr Endocrinol Metab | Evaluation of clinical, endocrine and metabolic findings in obese children with and without hepatosteatosis. | 2021 | Details |
| A03075 | 34141709 | Front Cell Dev Biol | New Insights Into the Role of Autophagy in Liver Surgery in the Setting of Metabolic Syndrome and Related Diseases. | 2021 | Details |
| A03100 | 34131333 | Nat Rev Endocrinol | Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus. | 2021 | Details |
| A03132 | 34118361 | Peptides | A synthetic peptide AWRK6 ameliorates metabolic associated fatty liver disease: involvement of lipid and glucose homeostasis. | 2021 | Details |
| A03146 | 34114325 | EMBO Rep | SCFJFK is functionally linked to obesity and metabolic syndrome. | 2021 | Details |
| A03163 | 34106786 | Am J Physiol Cell Physiol | Impaired Ca2+ signaling due to hepatic steatosis mediates hepatic insulin resistance in Alström syndrome mice that is reversed by GLP-1 analog treatment. | 2021 | Details |
| A03196 | 34093184 | Front Pharmacol | Bicyclol Regulates Hepatic Gluconeogenesis in Rats with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease by Inhibiting Inflammation. | 2021 | Details |
| A03213 | 34087824 | Medicine (Baltimore) | Soy diet for nonalcoholic fatty liver disease: A meta-analysis of randomized controlled trials. | 2021 | Details |
| A03217 | 34083664 | Sci Rep | Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH. | 2021 | Details |
| A03219 | 34083525 | Nat Commun | Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance. | 2021 | Details |
| A03226 | 34081289 | Hepatol Int | Histological severity of nonalcoholic fatty liver disease is associated with 10-year risk for atherosclerotic cardiovascular disease. | 2021 | Details |
| A03231 | 34078528 | BMB Rep | Porphyromonas gingivalis exacerbates the progression of fatty liver disease via CD36-PPARγ pathway. | 2021 | Details |
| A03235 | 34077443 | PLoS One | Severity of non-alcoholic steatohepatitis is not linked to testosterone concentration in patients with type 2 diabetes. | 2021 | Details |
| A03238 | 34074988 | Eur J Gastroenterol Hepatol | Association between aspartate aminotransferase-to-alanine aminotransferase ratio and insulin resistance among US adults. | 2022 | Details |
| A03245 | 34073834 | Int J Mol Sci | P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice. | 2021 | Details |
| A03257 | 34069012 | Int J Environ Res Public Health | Non-Alcoholic Fatty Liver Disease: Metabolic, Genetic, Epigenetic and Environmental Risk Factors. | 2021 | Details |
| A03259 | 34068699 | J Clin Med | Diabetic Kidney Disease, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease: A New Triumvirate? | 2021 | Details |
| A03280 | 34062716 | Int J Mol Sci | Role of Endocrine-Disrupting Chemicals in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review. | 2021 | Details |
| A03291 | 34058224 | Metabolism | Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1. | 2021 | Details |
| A03321 | 34046015 | Front Endocrinol (Lausanne) | Epigenetics of Hepatic Insulin Resistance. | 2021 | Details |
| A03322 | 34046014 | Front Endocrinol (Lausanne) | Spinal Cord Injury Reduces Serum Levels of Fibroblast Growth Factor-21 and Impairs Its Signaling Pathways in Liver and Adipose Tissue in Mice. | 2021 | Details |
| A03332 | 34040583 | Front Endocrinol (Lausanne) | Gene-Environmental Interactions as Metabolic Drivers of Nonalcoholic Steatohepatitis. | 2021 | Details |
| A03333 | 34040411 | J Inflamm Res | Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice. | 2021 | Details |
| A03341 | 34034750 | Lipids Health Dis | Circulating angiopoietin-like proteins in metabolic-associated fatty liver disease: a systematic review and meta-analysis. | 2021 | Details |
| A03371 | 34027116 | Clin Exp Hepatol | Comparative study of the effects of Abexol and atorvastatin in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A03372 | 34027109 | Clin Exp Hepatol | Non-alcoholic fatty liver disease and lipotoxicity. | 2021 | Details |
| A03377 | 34025131 | J Ginseng Res | Effect of Korean Red Ginseng on metabolic syndrome. | 2020 | Details |
| A03383 | 34022879 | BMC Endocr Disord | The application value of serum 25(OH)D3, uric acid, triglyceride, and homeostasis model assessment of insulin resistance in male patients with hyperuricemia combined with hypogonadism. | 2021 | Details |
| A03385 | 34022222 | J Biol Chem | Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide. | 2021 | Details |
| A03396 | 34017059 | Exp Mol Med | The interaction between the gut microbiota and dietary carbohydrates in nonalcoholic fatty liver disease. | 2021 | Details |
| A03400 | 34015596 | Int Immunopharmacol | Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies. | 2021 | Details |
| A03404 | 34014280 | Dis Model Mech | Synergic effect of atorvastatin and ambrisentan on sinusoidal and hemodynamic alterations in a rat model of NASH. | 2021 | Details |
| A03420 | 34006994 | Eur J Clin Nutr | Non-alcoholic fatty liver disease in obese children and adolescents: a role for nutrition? | 2021 | Details |
| A03424 | 34004342 | J Nutr Biochem | Saskatoon berry powder reduces hepatic steatosis and insulin resistance in high fat-high sucrose diet-induced obese mice. | 2021 | Details |
| A03426 | 34004161 | Gastroenterology | Associations Among Adipose Tissue Immunology, Inflammation, Exosomes and Insulin Sensitivity in People With Obesity and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03427 | 34003729 | Am J Respir Cell Mol Biol | Hepatocyte HIF-1 and Intermittent Hypoxia Independently Impact Liver Fibrosis in Murine Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03430 | 34002452 | Obes Rev | Bariatric surgery and the liver-Mechanisms, benefits, and risks. | 2021 | Details |
| A03447 | 33995543 | Evid Based Complement Alternat Med | Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03452 | 33994867 | Int J Biol Sci | MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |