Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A35260 | 21274277 | J Obes | Influence of Sleeve Gastrectomy on NASH and Type 2 Diabetes Mellitus. | 2010 | Details |
| A35307 | 21146362 | Int J Oral Maxillofac Surg | Non-alcoholic steatohepatitis (NASH) and oral lichen planus: a rare occurrence. | 2010 | Details |
| A35316 | 21119028 | Am J Physiol Endocrinol Metab | Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis. | 2010 | Details |
| A35317 | 21114431 | Scand J Gastroenterol | Non-alcoholic steatohepatitis (NASH) in patients with polycystic ovarian syndrome (PCOS). | 2010 | Details |
| A35325 | 21081801 | J Physiol Pharmacol | The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis. | 2010 | Details |
| A35327 | 21079817 | Acta Biochim Pol | Liver mitochondria and insulin resistance. | 2010 | Details |
| A35388 | 20846698 | Metabolism | Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. | 2010 | Details |
| A35412 | 20810317 | Curr Opin Pharmacol | Mechanisms of adiponectin regulation and use as a pharmacological target. | 2010 | Details |
| A35416 | 20803414 | Horm Metab Res | Dietary folic acid activates AMPK and improves insulin resistance and hepatic inflammation in dietary rodent models of the metabolic syndrome. | 2010 | Details |
| A35427 | 20724519 | Clin J Am Soc Nephrol | Relationship between kidney function and liver histology in subjects with nonalcoholic steatohepatitis. | 2010 | Details |
| A35433 | 20693650 | J Alzheimers Dis | Ceramide-mediated insulin resistance and impairment of cognitive-motor functions. | 2010 | Details |
| A35434 | 20683968 | Hepatology | Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. | 2010 | Details |
| A35444 | 20662773 | Aliment Pharmacol Ther | Pioglitazone in the treatment of NASH: the role of adiponectin. | 2010 | Details |
| A35445 | 20660987 | Exp Anim | Insulin resistance, steatohepatitis, and hepatocellular carcinoma in a new congenic strain of Fatty Liver Shionogi (FLS) mice with the Lep(ob) gene. | 2010 | Details |
| A35460 | 20607689 | Hepatology | High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. | 2010 | Details |
| A35472 | 20566747 | Am J Pathol | Histamine regulation in glucose and lipid metabolism via histamine receptors: model for nonalcoholic steatohepatitis in mice. | 2010 | Details |
| A35509 | 20489159 | Am J Pathol | A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits. | 2010 | Details |
| A35529 | 21949477 | Hepat Med | Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis. | 2010 | Details |
| A35530 | 20427778 | N Engl J Med | Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. | 2010 | Details |
| A35531 | 20425484 | Curr Gastroenterol Rep | Nontriglyceride hepatic lipotoxicity: the new paradigm for the pathogenesis of NASH. | 2010 | Details |
| A35570 | 20347818 | Gastroenterology | Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. | 2010 | Details |
| A35633 | 19996485 | J Physiol Pharmacol | Adipohormones as prognostric markers in patients with nonalcoholic steatohepatitis (NASH). | 2009 | Details |
| A35640 | 20041267 | Surg Endosc | Adiponectin but not leptin is involved in early hepatic disease in morbidly obese patients. | 2009 | Details |
| A35643 | 20034403 | Mol Neurodegener | Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment. | 2009 | Details |
| A35688 | 19906783 | J Clin Endocrinol Metab | Apoptotic markers indicate nonalcoholic steatohepatitis in polycystic ovary syndrome. | 2009 | Details |
| A35692 | 19902480 | Hepatology | Toxicant-associated steatohepatitis in vinyl chloride workers. | 2010 | Details |
| A35699 | 19884114 | Evid Based Complement Alternat Med | Antioxidant and hepatoprotective effects of silibinin in a rat model of nonalcoholic steatohepatitis. | 2011 | Details |
| A35700 | 19877169 | Hepatology | Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial. | 2010 | Details |
| A35720 | 19841616 | Lab Invest | Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress. | 2009 | Details |
| A35728 | 19824078 | Hepatology | Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. | 2009 | Details |
| A35772 | 19721198 | Clin Calcium | [Hepato-biliary and pancreatic disease and osteodystrophy]. | 2009 | Details |
| A35794 | 19676128 | Hepatology | Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. | 2009 | Details |
| A35799 | 19670459 | Hepatology | Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis. | 2009 | Details |
| A35801 | 19659788 | J Dig Dis | Diagnostic value of a group of biochemical markers of liver fibrosis in patients with non-alcoholic steatohepatitis. | 2009 | Details |
| A35864 | 19540686 | Gastroenterol Clin Biol | [Nonalcoholic fatty liver disease: 30 years research changed NASH]. | 2009 | Details |
| A35878 | 19513529 | Int J Mol Med | Epigallocatechin-3-gallate improves nonalcoholic steatohepatitis model mice expressing nuclear sterol regulatory element binding protein-1c in adipose tissue. | 2009 | Details |
| A35897 | 19473432 | Hepatol Res | Treatment of nonalcoholic steatohepatitis with colestimide. | 2009 | Details |
| A35907 | 19444873 | Hepatology | Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice. | 2009 | Details |
| A35909 | 19434740 | Hepatology | Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. | 2009 | Details |
| A35917 | 19416517 | BMC Res Notes | Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat. | 2009 | Details |
| A35922 | 21180541 | Therap Adv Gastroenterol | The Effect of Metformin and Standard Therapy versus Standard Therapy alone in Nondiabetic Patients with Insulin Resistance and Nonalcoholic Steatohepatitis (NASH): A Pilot Trial. | 2009 | Details |
| A35925 | 19394977 | Metabolism | Effects of adiponectin transgenic expression in liver of nonalcoholic steatohepatitis model mice. | 2009 | Details |
| A35934 | 19387107 | J Alzheimers Dis | Mechanisms of ceramide-mediated neurodegeneration. | 2009 | Details |
| A35951 | 19347015 | Nat Rev Gastroenterol Hepatol | Endocrine and liver interaction: the role of endocrine pathways in NASH. | 2009 | Details |
| A35952 | 19346775 | Nestle Nutr Workshop Ser Pediatr Program | Obesity, hepatic metabolism and disease. | 2009 | Details |
| A35965 | 19318968 | Eur J Gastroenterol Hepatol | Could inflammatory markers help diagnose nonalcoholic steatohepatitis? | 2009 | Details |
| A35968 | 19301087 | J Gastroenterol | Type 1 autoimmune hepatitis and adipokines: new markers for activity and disease progression? | 2009 | Details |
| A35974 | 19294996 | Rev Med Chir Soc Med Nat Iasi | [Involvement and role of iron in nonalcoholic steatohepatitis]. | 2009 | Details |
| A35989 | 19258673 | Acta Med Indones | Clinical picture, insulin resistance, and adipocytokines profiles of nonalcoholic steatohepatitis (NASH) patients in Indonesia. | 2009 | Details |
| A35999 | 19248193 | World J Gastroenterol | Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis. | 2009 | Details |
| A36013 | 19205029 | Hepatology | Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A(y) mice. | 2009 | Details |
| A36019 | 19195626 | Diabetes Metab | Insulin resistance and steatosis in humans. | 2008 | Details |
| A36021 | 19190144 | Cancer Epidemiol Biomarkers Prev | Iron overload is associated with hepatic oxidative damage to DNA in nonalcoholic steatohepatitis. | 2009 | Details |
| A36066 | 19085967 | Hepatology | Liver damage underlying unexplained transaminase elevation in human immunodeficiency virus-1 mono-infected patients on antiretroviral therapy. | 2009 | Details |
| A36077 | 19053005 | Z Gastroenterol | Adalimumab could suppress the activity of non alcoholic steatohepatitis (NASH). | 2008 | Details |
| A36096 | 19012034 | J Gastroenterol | Adipocytokines and liver disease. | 2008 | Details |
| A36106 | 19000661 | Chem Biol Interact | Fructose and carbonyl metabolites as endogenous toxins. | 2008 | Details |
| A36112 | 18991162 | Scand J Gastroenterol | Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice. | 2009 | Details |
| A36118 | 18984468 | Clin Liver Dis | Disease-specific mechanisms of fibrosis: hepatitis C virus and nonalcoholic steatohepatitis. | 2008 | Details |
| A36159 | 18848945 | Gastroenterology | Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice. | 2008 | Details |
| A36214 | 18718471 | Gastroenterology | Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis. | 2008 | Details |
| A36270 | 18571789 | Hepatology | Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis. | 2008 | Details |
| A36272 | 18563978 | Rev Esp Enferm Dig | [Gene expression in obese patients with non-alcoholic steatohepatitis]. | 2008 | Details |
| A36297 | 18503774 | Gastroenterology | Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial. | 2008 | Details |
| A36323 | 18459024 | Obes Surg | Fatty liver disease: predictors of nonalcoholic steatohepatitis and gallbladder disease in morbid obesity. | 2008 | Details |
| A36341 | 18408102 | Gut | Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis. | 2008 | Details |
| A36359 | 18369343 | Obesity (Silver Spring) | NASH predicts plasma inflammatory biomarkers independently of visceral fat in men. | 2008 | Details |
| A36376 | 18349116 | Am J Physiol Endocrinol Metab | Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice. | 2008 | Details |
| A36386 | 18325187 | Ann Clin Biochem | Adverse metabolic profiles in a cohort of obese Irish children. | 2008 | Details |
| A36404 | 18277895 | J Clin Gastroenterol | Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis. | 2008 | Details |
| A36429 | 18227531 | J Lipid Res | Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet. | 2008 | Details |
| A36439 | 18197877 | Hepatol Res | Combination of N-acetylcysteine and metformin improves histological steatosis and fibrosis in patients with non-alcoholic steatohepatitis. | 2008 | Details |
| A36469 | 18063353 | Nutr Metab Cardiovasc Dis | Molecular determinants of insulin resistance, cell apoptosis and lipid accumulation in non-alcoholic steatohepatitis. | 2007 | Details |
| A36487 | 18029322 | Adv Ther | Correlation of serum adiponectin levels and hepatic steatosis in hepatitis C virus genotype 1 infection. | 2008 | Details |
| A36534 | 17929294 | Hepatology | Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. | 2007 | Details |
| A36551 | 17873605 | Eur J Gastroenterol Hepatol | Primary liver cancers with nonalcoholic steatohepatitis. | 2007 | Details |
| A36598 | 17659580 | Hepatology | Evidence for a role of nonalcoholic steatohepatitis in hepatitis C: a prospective study. | 2007 | Details |
| A36606 | 17631134 | Gastroenterology | Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. | 2007 | Details |
| A36620 | 17599864 | Endocr Pract | The multifaceted associations of hepatobiliary disease and diabetes. | 2007 | Details |
| A36625 | 17588816 | Trends Mol Med | Targeting farnesoid X receptor for liver and metabolic disorders. | 2007 | Details |
| A36636 | 17559366 | J Gastroenterol Hepatol | Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis. | 2007 | Details |
| A36637 | 17559148 | Hepatology | The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis. | 2007 | Details |
| A36640 | 17544975 | Clin Liver Dis | Medical treatment of non-alcoholic steatohepatitis. | 2007 | Details |
| A36648 | 17530362 | J Gastroenterol | Type IV collagen 7s domain is an independent clinical marker of the severity of fibrosis in patients with nonalcoholic steatohepatitis before the cirrhotic stage. | 2007 | Details |
| A36672 | 17483780 | Gastroenterol Clin Biol | [Steatosis, chronic hepatitis virus C infection and homocysteine]. | 2007 | Details |
| A36681 | 17473493 | Intern Med | Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis. | 2007 | Details |
| A36699 | 17436085 | Dig Dis Sci | Rosiglitazone attenuates liver inflammation in a rat model of nonalcoholic steatohepatitis. | 2007 | Details |
| A36702 | 17429733 | Dig Dis Sci | The serum endothelin-1 level in steatosis and NASH, and its relation with severity of liver fibrosis. | 2007 | Details |
| A36714 | 17404856 | Dig Dis Sci | Orlistat reverse fatty infiltration and improves hepatic fibrosis in obese patients with nonalcoholic steatohepatitis (NASH). | 2007 | Details |
| A36718 | 17393512 | Hepatology | Chronic intermittent hypoxia predisposes to liver injury. | 2007 | Details |
| A36719 | 17392582 | Mediators Inflamm | Serum adipokine and ghrelin levels in nonalcoholic steatohepatitis. | 2006 | Details |
| A36722 | 17388862 | Intern Med J | Effects of vitamin E treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: results of a pilot study. | 2007 | Details |
| A36726 | 17379003 | Metabolism | Transgenic mice expressing nuclear sterol regulatory element-binding protein 1c in adipose tissue exhibit liver histology similar to nonalcoholic steatohepatitis. | 2007 | Details |
| A36750 | 17335930 | J Hepatol | Differences and similarities in early atherosclerosis between patients with non-alcoholic steatohepatitis and chronic hepatitis B and C. | 2007 | Details |
| A36751 | 17335677 | Curr Gastroenterol Rep | Treatment of fibrosis in nonalcoholic fatty liver disease. | 2007 | Details |
| A36760 | 17322381 | Am J Pathol | Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis. | 2007 | Details |
| A36761 | 17315588 | Ceylon Med J | Metabolic consequences of childhood obesity--a preliminary report. | 2006 | Details |
| A36768 | 17300698 | Hepatol Res | Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet. | 2007 | Details |
| A36801 | 17241878 | Gastroenterology | Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. | 2006 | Details |
| A36805 | 17229244 | Aliment Pharmacol Ther | Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia. | 2007 | Details |