Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52718 | 22895358 | Curr Opin Endocrinol Diabetes Obes | Are there still healthy obese patients? | 2012 | Details |
| A52722 | 22829562 | Endocr Rev | Cardiometabolic aspects of the polycystic ovary syndrome. | 2012 | Details |
| A52723 | 22825472 | Cell Death Dis | Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity. | 2012 | Details |
| A52724 | 22820893 | Endocrine | Fetuin-A and angiopoietins in obesity and type 2 diabetes mellitus. | 2012 | Details |
| A52725 | 22819899 | Hepatogastroenterology | Adiponectin and its receptors in chronic hepatitis B patients with metabolic syndrome in China. | 2012 | Details |
| A52733 | 22670657 | Scand J Gastroenterol | Serum FGF21 and RBP4 levels in patients with chronic hepatitis C. | 2012 | Details |
| A52734 | 22664476 | J Clin Gastroenterol | Association of serum adipocytokines with insulin resistance and liver injury in patients with chronic hepatitis C genotype 4. | 2013 | Details |
| A52741 | 22546774 | Int J Obes (Lond) | PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study. | 2012 | Details |
| A52742 | 22546076 | Atherosclerosis | Multiple factors and pathways involved in hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima Fatty rats. | 2012 | Details |
| A52744 | 22506114 | Biochem Res Int | Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes. | 2012 | Details |
| A52745 | 22504062 | J Ethnopharmacol | Populus balsamifera L. (Salicaceae) mitigates the development of obesity and improves insulin sensitivity in a diet-induced obese mouse model. | 2012 | Details |
| A52746 | 22493234 | Proc Natl Acad Sci U S A | Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. | 2012 | Details |
| A52749 | 22481453 | Ann Hepatol | Serum adipocyte fatty acid binding protein in liver transplant recipients and the metabolic syndrome. | 2012 | Details |
| A52750 | 22475652 | Diabetol Metab Syndr | High plasma uric acid concentration: causes and consequences. | 2012 | Details |
| A52751 | 22471957 | Cardiovasc Hematol Agents Med Chem | PPAR- γ agonist in treatment of diabetes: cardiovascular safety considerations. | 2012 | Details |
| A52753 | 22428554 | J Immunotoxicol | Effects of pioglitazone and/or simvastatin on circulating TNFα and adiponectin levels in insulin resistance. | 2012 | Details |
| A52756 | 22414273 | J Gastroenterol Hepatol | Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity. | 2012 | Details |
| A52758 | 22393439 | PLoS One | Fatty liver index predicts further metabolic deteriorations in women with previous gestational diabetes. | 2012 | Details |
| A52759 | 22382323 | Biol Pharm Bull | Fenretinide ameliorates insulin resistance and fatty liver in obese mice. | 2012 | Details |
| A52760 | 22351884 | Pediatrics | Toward a unifying hypothesis of metabolic syndrome. | 2012 | Details |
| A52764 | 22318315 | Obesity (Silver Spring) | Adropin deficiency is associated with increased adiposity and insulin resistance. | 2012 | Details |
| A52768 | 22276255 | Indian J Endocrinol Metab | Metabolic syndrome in the Mediterranean region: Current status. | 2012 | Details |
| A52774 | 22185842 | Am J Physiol Endocrinol Metab | Generation and characterization of a mouse model of the metabolic syndrome: apolipoprotein E and aromatase double knockout mice. | 2011 | Details |
| A52776 | 22158268 | Int J Obes (Lond) | Impact of BMI on the incidence of metabolic abnormalities in metabolically healthy men. | 2011 | Details |
| A52778 | 22074439 | Curr Pharm Des | Evaluation of the possible contribution of antioxidants administration in metabolic syndrome. | 2011 | Details |
| A52782 | 22014839 | J Am Soc Echocardiogr | Epicardial adipose tissue relating to anthropometrics, metabolic derangements and fatty liver disease independently contributes to serum high-sensitivity C-reactive protein beyond body fat composition: a study validated with computed tomography. | 2011 | Details |
| A52783 | 22005032 | Biochim Biophys Acta | Hypertriglyceridemia secondary to obesity and diabetes. | 2011 | Details |
| A52784 | 21979150 | Biochim Biophys Acta | Fatty acid transport proteins, implications in physiology and disease. | 2011 | Details |
| A52786 | 21934202 | Indian J Pathol Microbiol | Steatosis in chronic hepatitis B: prevalence and correlation with biochemical, histologic, viral, and metabolic parameters. | 2012 | Details |
| A52787 | 21932846 | J Agric Food Chem | Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice. | 2011 | Details |
| A52788 | 21923735 | Diabetes Obes Metab | The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects. | 2011 | Details |
| A52790 | 21900826 | Eur J Gastroenterol Hepatol | Sex and race differences in the prevalence of fatty liver disease as measured by computed tomography liver attenuation in European American and African American participants of the NHLBI family heart study. | 2012 | Details |
| A52791 | 21892913 | Clin Chem Lab Med | New insights into adipose tissue dysfunction in insulin resistance. | 2011 | Details |
| A52793 | 21852815 | Obesity (Silver Spring) | Intestinal permeability is associated with visceral adiposity in healthy women. | 2011 | Details |
| A52794 | 21849896 | Curr Opin Clin Nutr Metab Care | Origins of metabolic complications in obesity: adipose tissue and free fatty acid trafficking. | 2011 | Details |
| A52796 | 21817098 | Arterioscler Thromb Vasc Biol | CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice. | 2011 | Details |
| A52800 | 21725989 | Hepatology | Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. | 2011 | Details |
| A52801 | 21723507 | Cell Metab | Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome. | 2011 | Details |
| A52802 | 21613559 | Am J Clin Nutr | Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions. | 2011 | Details |
| A52804 | 21549160 | Regul Pept | GLP-1-derived nonapeptide GLP-1(28-36)amide inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
| A52805 | 21536228 | Gend Med | Relations of adiponectin to levels of metabolic parameters and sexual hormones in elderly type 2 diabetic patients. | 2011 | Details |
| A52808 | 21490364 | Am J Physiol Regul Integr Comp Physiol | Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity. | 2011 | Details |
| A52809 | 21488080 | Hepatology | Fatty liver index and mortality: the Cremona study in the 15th year of follow-up. | 2011 | Details |
| A52813 | 21429276 | Br J Nutr | Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. | 2011 | Details |
| A52814 | 21406612 | Am J Physiol Endocrinol Metab | Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1. | 2011 | Details |
| A52815 | 21386801 | Int J Obes (Lond) | Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. | 2011 | Details |
| A52816 | 21382161 | Liver Int | Hepatic steatosis and insulin resistance are associated with severe fibrosis in patients with chronic hepatitis caused by HBV or HCV infection. | 2011 | Details |
| A52821 | 21310864 | J Nutr | Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. | 2011 | Details |
| A52823 | 21270262 | Diabetes | Hypoxia-induced intrauterine growth restriction increases the susceptibility of rats to high-fat diet-induced metabolic syndrome. | 2011 | Details |
| A52824 | 21258310 | Med Glas (Zenica) | Increased P wave dispersion in patients with liver steatosis. | 2010 | Details |
| A52826 | 21250778 | Arch Physiol Biochem | Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome? | 2011 | Details |
| A52827 | 21199519 | J Gastroenterol Hepatol | Hepatic steatosis and hepatitis C: Still unhappy bedfellows? | 2011 | Details |
| A52828 | 21194577 | Am J Med | Initial combination therapy for type 2 diabetes mellitus: is it ready for prime time? | 2011 | Details |
| A52829 | 21205225 | Basic Clin Pharmacol Toxicol | Monosodium glutamate neonatal intoxication associated with obesity in adult stage is characterized by chronic inflammation and increased mRNA expression of peroxisome proliferator-activated receptors in mice. | 2011 | Details |
| A52831 | 21178610 | Curr Opin Clin Nutr Metab Care | Fatty acid regulation of hepatic lipid metabolism. | 2011 | Details |
| A52832 | 21151924 | PLoS One | Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice. | 2010 | Details |
| A52833 | 21145849 | J Hepatol | Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. | 2010 | Details |
| A52834 | 21112030 | Best Pract Res Clin Endocrinol Metab | Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea. | 2010 | Details |
| A52839 | 21060311 | Int J Obes (Lond) | Perinatal nutrient restriction induces long-lasting alterations in the circadian expression pattern of genes regulating food intake and energy metabolism. | 2010 | Details |
| A52840 | 21036943 | Hum Mol Genet | Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance. | 2010 | Details |
| A52841 | 20980637 | J Nutr | Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs. | 2010 | Details |
| A52843 | 20961644 | J Hepatol | Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease. | 2010 | Details |
| A52845 | 20835701 | Diabetologia | Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. | 2010 | Details |
| A52846 | 20832799 | Atherosclerosis | High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits. | 2010 | Details |
| A52847 | 20824098 | PLoS One | Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. | 2010 | Details |
| A52848 | 20725711 | J Mol Med (Berl) | Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. | 2010 | Details |
| A52853 | 20670429 | Lipids Health Dis | Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats. | 2010 | Details |
| A52854 | 20649581 | Br J Pharmacol | Irbesartan treatment up-regulates hepatic expression of PPARalpha and its target genes in obese Koletsky (fa(k)/fa(k)) rats: a link to amelioration of hypertriglyceridaemia. | 2010 | Details |
| A52855 | 20625970 | Horm Metab Res | Combination therapy with nateglinide and vildagliptin improves postprandial metabolic derangements in Zucker fatty rats. | 2010 | Details |
| A52857 | 20592272 | Endocr Rev | Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk. | 2010 | Details |
| A52862 | 20536513 | Diabet Med | Do high ferritin levels confer lower cardiovascular risk in men with Type 2 diabetes? | 2010 | Details |
| A52865 | 20495737 | Rom J Morphol Embryol | Hepatocyte steatosis in patients infected with genotype 1 hepatitis C virus. | 2010 | Details |
| A52867 | 20480550 | Curr Opin Lipidol | Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein. | 2010 | Details |
| A52873 | 20376319 | PLoS One | The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity. | 2010 | Details |
| A52874 | 20361178 | Diabetologia | Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. | 2010 | Details |
| A52875 | 20340066 | Horm Metab Res | Leptin treatment during lactation programs leptin synthesis, intermediate metabolism, and liver microsteatosis in adult rats. | 2010 | Details |
| A52876 | 20336705 | Hepatology | Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study. | 2010 | Details |
| A52882 | 20110573 | Arterioscler Thromb Vasc Biol | Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice. | 2010 | Details |
| A52886 | 20021538 | J Clin Hypertens (Greenwich) | Pathogenesis and pathophysiology of the cardiometabolic syndrome. | 2009 | Details |
| A52891 | 19920214 | Am J Physiol Endocrinol Metab | Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERalpha-deficient mice. | 2009 | Details |
| A52892 | 19875992 | Obesity (Silver Spring) | The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome. | 2009 | Details |
| A52893 | 19859993 | World J Gastroenterol | Steatosis and insulin resistance in hepatitis C: a way out for the virus? | 2009 | Details |
| A52896 | 19850541 | An Pediatr (Barc) | [Fatty liver disease, insulin resistance and adiponectin in an obese pediatric population]. | 2009 | Details |
| A52897 | 19844213 | Int J Obes (Lond) | Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. | 2009 | Details |
| A52898 | 19822001 | Lipids Health Dis | A high oleic sunflower oil fatty acid esters of plant sterols mixed with dietary diacylglycerol reduces plasma insulin and body fat accumulation in Psammomys obesus. | 2009 | Details |
| A52899 | 19809411 | Am J Gastroenterol | Interaction of adipokines and hepatitis B virus on histological liver injury in the Chinese. | 2009 | Details |
| A52901 | 19796990 | Curr Opin Pharmacol | The role of mitochondria in health and disease. | 2009 | Details |
| A52902 | 19796707 | Biochim Biophys Acta | Hypothalamic lipotoxicity and the metabolic syndrome. | 2009 | Details |
| A52903 | 19796705 | Biochim Biophys Acta | Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome. | 2009 | Details |
| A52904 | 19773738 | Int J Obes (Lond) | Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. | 2009 | Details |
| A52907 | 19729476 | Am J Pathol | Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells. | 2009 | Details |
| A52909 | 19690766 | Rom J Morphol Embryol | Role of oxidative stress in the pathogenesis of chronic hepatitis C (CHC). | 2009 | Details |
| A52913 | 19631025 | Br J Nutr | Experimental rat models to study the metabolic syndrome. | 2009 | Details |
| A52914 | 19623253 | PLoS One | Humanin: a novel central regulator of peripheral insulin action. | 2009 | Details |
| A52915 | 19584878 | Obesity (Silver Spring) | Metabolic implications of dietary trans-fatty acids. | 2009 | Details |
| A52921 | 19509184 | Am J Physiol Endocrinol Metab | Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis. | 2009 | Details |
| A52922 | 19501581 | Clin Biochem | Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. | 2009 | Details |
| A52927 | 19421860 | Apoptosis | Diabetes and apoptosis: lipotoxicity. | 2009 | Details |
| A52932 | 19358089 | Exp Clin Endocrinol Diabetes | Adipose tissue dysfunction in obesity. | 2009 | Details |
| A52933 | 19357846 | Semin Immunopathol | The emerging role of the endocannabinoid system in cardiovascular disease. | 2009 | Details |