Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04653 | 33550587 | Hepatology | Heterogeneity of HSCs in a Mouse Model of NASH. | 2021 | Details |
| A04659 | 33549441 | Nutr Metab Cardiovasc Dis | Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: A single lipid center real-world experience. | 2020 | Details |
| A04660 | 33548473 | J Nutr Biochem | Tomatidine ameliorates obesity-induced nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A04661 | 33548472 | J Nutr Biochem | Dietary lycopene attenuates cigarette smoke-promoted nonalcoholic steatohepatitis by preventing suppression of antioxidant enzymes in ferrets. | 2021 | Details |
| A04667 | 33546405 | Nutrients | Effects of Long-Term DHA Supplementation and Physical Exercise on Non-Alcoholic Fatty Liver Development in Obese Aged Female Mice. | 2021 | Details |
| A04670 | 33546130 | Nutrients | Dietary Polyphenols and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04685 | 33542911 | Can J Gastroenterol Hepatol | Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice. | 2021 | Details |
| A04696 | 33536590 | Sci Rep | The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs. | 2021 | Details |
| A04698 | 33536442 | Sci Rep | Clinical implications of renin-angiotensin system inhibitors for development and progression of non-alcoholic fatty liver disease. | 2021 | Details |
| A04700 | 33535836 | Expert Rev Clin Pharmacol | An update on drug development for the treatment of nonalcoholic fatty liver disease - from ongoing clinical trials to future therapy. | 2021 | Details |
| A04713 | 33531575 | Sci Rep | High-fructose feeding does not induce steatosis or non-alcoholic fatty liver disease in pigs. | 2021 | Details |
| A04717 | 33530432 | Antioxidants (Basel) | Role of Oxidative Stress in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Implications for Prevention and Therapy. | 2021 | Details |
| A04723 | 33528280 | Scand J Clin Lab Invest | Chronic inflammation involves CCL11 and IL-13 to facilitate the development of liver cirrhosis and fibrosis in chronic hepatitis B virus infection. | 2021 | Details |
| A04725 | 33526807 | Lab Invest | NLRP3 deficiency did not attenuate NASH development under high fat calorie diet plus high fructose and glucose in drinking water. | 2021 | Details |
| A04729 | 33525493 | Cells | Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations. | 2021 | Details |
| A04730 | 33525359 | Int J Mol Sci | Fatty Acids and a High-Fat Diet Induce Epithelial-Mesenchymal Transition by Activating TGFβ and β-Catenin in Liver Cells. | 2021 | Details |
| A04734 | 33522200 | J Tradit Chin Med | Efficacy of Cigu Xiaozhi pill on non-alcoholic steatohepatitis-associated lipoapoptosis through stress-activated c-Jun N-terminal kinase signalling pathway. | 2021 | Details |
| A04745 | 33516698 | Life Sci | Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis. | 2021 | Details |
| A04752 | 33515562 | Life Sci | miR-125b promotes the NF-κB-mediated inflammatory response in NAFLD via directly targeting TNFAIP3. | 2021 | Details |
| A04760 | 33513646 | Dtsch Med Wochenschr | [The harmfulness of simple steatosis]. | 2021 | Details |
| A04763 | 33513397 | Life Sci | The influence of PM2.5 exposure on non-alcoholic fatty liver disease. | 2021 | Details |
| A04775 | 33510844 | Oxid Med Cell Longev | Phloroglucinol Strengthens the Antioxidant Barrier and Reduces Oxidative/Nitrosative Stress in Nonalcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A04776 | 33510172 | Nat Commun | CD4 derived double negative T cells prevent the development and progression of nonalcoholic steatohepatitis. | 2021 | Details |
| A04787 | 33505505 | Evid Based Complement Alternat Med | A Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology. | 2021 | Details |
| A04788 | 33505393 | Front Immunol | Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions. | 2021 | Details |
| A04799 | 33501889 | Am J Physiol Gastrointest Liver Physiol | A dietary ketone ester mitigates histological outcomes of NAFLD and markers of fibrosis in high-fat diet fed mice. | 2021 | Details |
| A04801 | 33501739 | Pediatr Obes | Association of leukocyte telomere length with obesity-related traits in Asian children with early-onset obesity. | 2021 | Details |
| A04806 | 33498684 | Plants (Basel) | Plants of the Spontaneous Flora with Beneficial Action in the Management of Diabetes, Hepatic Disorders, and Cardiovascular Disease. | 2021 | Details |
| A04818 | 33494735 | BMC Complement Med Ther | Yellow loosestrife (Lysimachia vulgaris var. davurica) ameliorates liver fibrosis in db/db mice with methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis. | 2021 | Details |
| A04820 | 33494295 | Cells | Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways. | 2021 | Details |
| A04822 | 33493657 | Pharmacol Res | Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects. | 2021 | Details |
| A04826 | 33492571 | Mol Biol Rep | Association of xenobiotic-metabolizing enzymes (GSTM1 and GSTT 1), and pro-inflammatory cytokines (TNF-α and IL-6) genetic polymorphisms with non-alcoholic fatty liver disease. | 2021 | Details |
| A04866 | 33476308 | J Clin Invest | Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis. | 2021 | Details |
| A04870 | 33474802 | Pharmacol Res Perspect | Dexmedetomidine ameliorates high-fat diet-induced nonalcoholic fatty liver disease by targeting SCD1 in obesity mice. | 2021 | Details |
| A04884 | 33467546 | Int J Mol Sci | Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis. | 2021 | Details |
| A04887 | 33465844 | Clin Mol Hepatol | Serum lipocalin-2 is a potential biomarker for the clinical diagnosis of nonalcoholic steatohepatitis. | 2021 | Details |
| A04896 | 33461969 | BMJ | Management of non-alcoholic fatty liver disease. | 2021 | Details |
| A04899 | 33460628 | Biochem Pharmacol | Prenatal dexamethasone exposure induces nonalcoholic fatty liver disease in male rat offspring via the miR-122/YY1/ACE2-MAS1 pathway. | 2021 | Details |
| A04947 | 33440736 | Nutrients | Bifidobacterium breve CNCM I-4035, Lactobacillus paracasei CNCM I-4034 and Lactobacillus rhamnosus CNCM I-4036 Modulate Macrophage Gene Expression and Ameliorate Damage Markers in the Liver of Zucker-Lepr fa/fa Rats. | 2021 | Details |
| A04951 | 33439102 | Am J Physiol Gastrointest Liver Physiol | Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. | 2021 | Details |
| A04958 | 33437901 | Hepatol Commun | Major Histocompatibility Complex Class I-Related Chain A Alleles and Histology of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A04963 | 33436955 | Sci Rep | LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH. | 2021 | Details |
| A04978 | 33429022 | Free Radic Biol Med | Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress. | 2021 | Details |
| A04981 | 33426876 | J Agric Food Chem | Anti-Inflammatory, Antioxidant, and Anti-Nonalcoholic Steatohepatitis Acylphloroglucinol Meroterpenoids from Hypericum bellum Flowers. | 2021 | Details |
| A04983 | 33426540 | J Cell Immunol | Maternal Diet Alters Trained Immunity in the Pathogenesis of Pediatric NAFLD. | 2020 | Details |
| A04986 | 33424768 | Front Endocrinol (Lausanne) | Harnessing Muscle-Liver Crosstalk to Treat Nonalcoholic Steatohepatitis. | 2020 | Details |
| A04992 | 33421970 | Turk J Med Sci | The effect of 1,25-dihydroxyvitamin D3 on liver damage, oxidative stress, and advanced glycation end products in experimental nonalcoholic- and alcoholic- fatty liver disease | 2021 | Details |
| A04997 | 33421258 | J Biochem Mol Toxicol | The protective effects of trelagliptin on high-fat diet-induced nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A05000 | 33419084 | Antioxidants (Basel) | Antioxidant and Anti-Inflammatory Effects of Korean Black Ginseng Extract through ER Stress Pathway. | 2021 | Details |
| A05003 | 33417955 | Life Sci | Sacran, a sulfated polysaccharide, suppresses the absorption of lipids and modulates the intestinal flora in non-alcoholic steatohepatitis model rats. | 2021 | Details |
| A05006 | 33414764 | Front Endocrinol (Lausanne) | FGF19 and FGF21 for the Treatment of NASH-Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human. | 2020 | Details |
| A05011 | 33411880 | Food Funct | Berbamine induced activation of the SIRT1/LKB1/AMPK signaling axis attenuates the development of hepatic steatosis in high-fat diet-induced NAFLD rats. | 2021 | Details |
| A05012 | 33410857 | Food Funct | Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling. | 2021 | Details |
| A05018 | 33409398 | Transl Gastroenterol Hepatol | Gut microbiome changes in Nonalcoholic fatty liver disease & alcoholic liver disease. | 2021 | Details |
| A05019 | 33409397 | Transl Gastroenterol Hepatol | Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). | 2021 | Details |
| A05028 | 33404223 | J Agric Food Chem | Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner. | 2021 | Details |
| A05029 | 33404166 | Int J Clin Pract | The association of the adipokine zinc-alpha2-glycoprotein with non-alcoholic fatty liver disease and related risk factors: A comprehensive systematic review. | 2021 | Details |
| A05034 | 33400402 | J Cell Mol Med | Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation. | 2021 | Details |
| A05037 | 33398776 | Hepatol Int | Elobixibat, an ileal bile acid transporter inhibitor, ameliorates non-alcoholic steatohepatitis in mice. | 2021 | Details |
| A05043 | 33396939 | Int J Mol Sci | Deletion of KLF10 Leads to Stress-Induced Liver Fibrosis upon High Sucrose Feeding. | 2020 | Details |
| A05044 | 33396535 | Int J Mol Sci | Exosomal miRNAs as Potential Biomarkers to Monitor Phosphodiesterase 5 Inhibitor Induced Anti-Fibrotic Effects on CCl4 Treated Rats. | 2020 | Details |
| A05058 | 33391254 | Front Immunol | A Mineralocorticoid Receptor Deficiency in Myeloid Cells Reduces Liver Steatosis by Impairing Activation of CD8+ T Cells in a Nonalcoholic Steatohepatitis Mouse Model. | 2020 | Details |
| A05062 | 33390939 | Front Pharmacol | Inulin Exerts Beneficial Effects on Non-Alcoholic Fatty Liver Disease via Modulating gut Microbiome and Suppressing the Lipopolysaccharide-Toll-Like Receptor 4-Mψ-Nuclear Factor-κB-Nod-Like Receptor Protein 3 Pathway via gut-Liver Axis in Mice. | 2020 | Details |
| A05067 | 33388954 | Pediatr Surg Int | The administration of hepatocyte growth factor prevents total parenteral nutrition-induced hepatocellular injury in a rat model. | 2021 | Details |
| A05080 | 33385317 | J Dig Dis | Efficacy and safety of drugs for nonalcoholic steatohepatitis. | 2021 | Details |
| A05081 | 33384662 | Front Endocrinol (Lausanne) | Chronic Inflammation in Non-Alcoholic Steatohepatitis: Molecular Mechanisms and Therapeutic Strategies. | 2020 | Details |
| A05083 | 33384552 | World J Gastroenterol | Prevalence and associated factors of obesity in inflammatory bowel disease: A case-control study. | 2020 | Details |
| A05085 | 33383448 | Int Immunopharmacol | Therapeutic potential of bicyclol in liver diseases: Lessons from a synthetic drug based on herbal derivative in traditional Chinese medicine. | 2020 | Details |
| A05094 | 33378966 | Biomed Pharmacother | Potential effects of SARS-CoV-2 on the gastrointestinal tract and liver. | 2020 | Details |
| A05124 | 33363621 | Oncol Lett | Biological effects of corosolic acid as an anti-inflammatory, anti-metabolic syndrome and anti-neoplasic natural compound. | 2020 | Details |
| A05125 | 33363517 | Front Endocrinol (Lausanne) | The Role of Thyroid Hormones and Autoantibodies in Metabolic Dysfunction Associated Fatty Liver Disease: TgAb May Be a Potential Protective Factor. | 2020 | Details |
| A05129 | 33362721 | Front Endocrinol (Lausanne) | Oxidation-Specific Epitopes in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05130 | 33362390 | World J Gastroenterol | Prevalence and risk factors of nonalcoholic fatty liver disease in patients with inflammatory bowel diseases: A cross-sectional and longitudinal analysis. | 2020 | Details |
| A05154 | 33352441 | Int Immunopharmacol | Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses. | 2020 | Details |
| A05155 | 33352229 | Pharmacol Res | Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases. | 2020 | Details |
| A05157 | 33350984 | JCI Insight | Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90. | 2021 | Details |
| A05173 | 33346578 | J Pediatr Gastroenterol Nutr | Evaluation of Nonalcoholic Fatty Liver Disease in Pediatric Patients With Inflammatory Bowel Disease. | 2021 | Details |
| A05184 | 33343673 | Evid Based Complement Alternat Med | Investigation of the Synergistic Effect of Brown Sugar, Longan, Ginger, and Jujube (Brown Sugar Longan Ginger Tea) on Antioxidation and Anti-Inflammation in In Vitro Models. | 2020 | Details |
| A05187 | 33343352 | Front Pharmacol | Hepatoprotective Effect and Molecular Mechanisms of Hengshun Aromatic Vinegar on Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05190 | 33341674 | Biochem Biophys Res Commun | Hepatocyte-specific TAZ deletion downregulates p62/ Sqstm1 expression in nonalcoholic steatohepatitis. | 2020 | Details |
| A05192 | 33341045 | Biomed Pharmacother | β-patchoulene improves lipid metabolism to alleviate non-alcoholic fatty liver disease via activating AMPK signaling pathway. | 2020 | Details |
| A05193 | 33341026 | Phytomedicine | Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice. | 2020 | Details |
| A05207 | 33339155 | Antioxidants (Basel) | N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature. | 2020 | Details |
| A05212 | 33337101 | Compr Rev Food Sci Food Saf | Phytosterols and their derivatives: Potential health-promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues. | 2020 | Details |
| A05223 | 33333240 | Respir Physiol Neurobiol | Functional foods from the tropics to relieve chronic normobaric hypoxia. | 2020 | Details |
| A05226 | 33332766 | Immun Inflamm Dis | Inflammation initiates a vicious cycle between obesity and nonalcoholic fatty liver disease. | 2020 | Details |
| A05227 | 33331485 | Arq Gastroenterol | GUT MICROBIOTA, PREBIOTICS, PROBIOTICS, AND SYNBIOTICS IN GASTROINTESTINAL AND LIVER DISEASES: PROCEEDINGS OF A JOINT MEETING OF THE BRAZILIAN SOCIETY OF HEPATOLOGY (SBH), BRAZILIAN NUCLEUS FOR THE STUDY OF HELICOBACTER PYLORI AND MICROBIOTA (NBEHPM), AND BRAZILIAN FEDERATION OF GASTROENTEROLOGY (FBG). | 2021 | Details |
| A05244 | 33326684 | IUBMB Life | Combination of metformin and chlorogenic acid attenuates hepatic steatosis and inflammation in high-fat diet fed mice. | 2020 | Details |
| A05246 | 33325949 | Food Funct | Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis. | 2020 | Details |
| A05250 | 33324345 | Front Endocrinol (Lausanne) | Repression of MicroRNA-124-3p Alleviates High-Fat Diet-Induced Hepatosteatosis by Targeting Pref-1. | 2020 | Details |
| A05252 | 33323025 | AIDS Res Hum Retroviruses | Pro-Inflammatory Interleukin-18 is Associated with Hepatic Steatosis and Elevated Liver Enzymes in People with HIV Monoinfection. | 2021 | Details |
| A05253 | 33322323 | Animals (Basel) | GC-TOF-MS-Based Metabolomics Analyses of Liver and Intestinal Contents in the Overfed vs. Normally-Fed Geese. | 2020 | Details |
| A05255 | 33321448 | Complement Ther Clin Pract | Efficacy of resveratrol supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trials. | 2020 | Details |
| A05256 | 33321020 | Acta Gastroenterol Belg | Proteins involved in lipid metabolism as possible biomarkers or predisposing factors for non-alcoholic fatty liver disease. | 2020 | Details |
| A05260 | 33320545 | ACS Biomater Sci Eng | Modeling Human Nonalcoholic Fatty Liver Disease (NAFLD) with an Organoids-on-a-Chip System. | 2020 | Details |
| A05276 | 33317065 | Biomedicines | Dietary-Induced Low-Grade Inflammation in the Liver. | 2020 | Details |
| A05278 | 33315911 | PLoS One | The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension. | 2020 | Details |
| A05284 | 33312845 | Curr Treat Options Pediatr | When the beverage is sweet, how does the liver feel? | 2019 | Details |
| A05287 | 33312420 | World J Hepatol | Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo. | 2020 | Details |
| A05293 | 33310185 | Biochem Biophys Res Commun | Impaired CCR9/CCL25 signalling induced by inefficient dendritic cells contributes to intestinal immune imbalance in nonalcoholic steatohepatitis. | 2020 | Details |