Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06266 | 32947564 | J Pediatr Gastroenterol Nutr | Lipidomics in Nonalcoholic Fatty Liver Disease: Exploring Serum Lipids as Biomarkers for Pediatric Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06272 | 32945408 | Mol Med Rep | Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats. | 2020 | Details |
| A06277 | 32944984 | J Food Biochem | trans-Chalcone inhibits high-fat diet-induced disturbances in FXR/SREBP-1c/FAS and FXR/Smad-3 pathways in the kidney of rats. | 2020 | Details |
| A06303 | 32935743 | Arq Gastroenterol | DISTINCT PHENOTYPE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH LOW LEVELS OF FREE COPPER AND OF CERULOPLASMIN. | 2021 | Details |
| A06305 | 32934691 | Exp Ther Med | Abnormal metabolic processes involved in the pathogenesis of non-alcoholic fatty liver disease (Review). | 2020 | Details |
| A06309 | 32933722 | Tissue Cell | Liraglutide in combination with human umbilical cord mesenchymal stem cell could improve liver lesions by modulating TLR4/NF-kB inflammatory pathway and oxidative stress in T2DM/NAFLD rats. | 2020 | Details |
| A06314 | 32932529 | Exp Clin Endocrinol Diabetes | Liver Expressed Antimicrobial Peptide 2 is Associated with Steatosis in Mice and Humans. | 2020 | Details |
| A06326 | 32928450 | J Sport Health Sci | Regular moderate aerobic exercise improves high-fat diet-induced nonalcoholic fatty liver disease via monoacylglycerol O-acyltransferase 1 pathway suppression. | 2018 | Details |
| A06335 | 32924526 | Am J Physiol Endocrinol Metab | Differences in metabolic and liver pathobiology induced by two dietary mouse models of nonalcoholic fatty liver disease. | 2020 | Details |
| A06339 | 32923658 | Cannabis Cannabinoid Res | Cannabis Extracts Affected Metabolic Syndrome Parameters in Mice Fed High-Fat/Cholesterol Diet. | 2020 | Details |
| A06347 | 32920973 | Mol Nutr Food Res | Dietary Rapeseed Oil Supplementation Reduces Hepatic Steatosis in Obese Men-A Randomized Controlled Trial. | 2020 | Details |
| A06355 | 32918742 | J Pathol | Differential TM4SF5-mediated SIRT1 modulation and metabolic signaling in nonalcoholic steatohepatitis progression. | 2020 | Details |
| A06356 | 32918399 | Environ Toxicol | Sorafenib reduces steatosis-induced fibrogenesis in a human 3D co-culture model of non-alcoholic fatty liver disease. | 2020 | Details |
| A06357 | 32916992 | Molecules | LRRK2 Regulates CPT1A to Promote β-Oxidation in HepG2 Cells. | 2020 | Details |
| A06360 | 32916379 | Nutrition | Pleiotropic ameliorative effects of ellagitannin geraniin against metabolic syndrome induced by high-fat diet in rats. | 2020 | Details |
| A06368 | 32910776 | Diabetes Care | Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes. | 2020 | Details |
| A06382 | 32905826 | Toxicology | Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro. | 2020 | Details |
| A06387 | 32899418 | Biomolecules | Hepatic Lipidomics and Molecular Imaging in a Murine Non-Alcoholic Fatty Liver Disease Model: Insights into Molecular Mechanisms. | 2020 | Details |
| A06400 | 32892668 | Expert Rev Gastroenterol Hepatol | Non-alcoholic fatty liver disease: molecular and cellular interplays of the lipid metabolism in a steatotic liver. | 2020 | Details |
| A06402 | 32892401 | Scand J Immunol | Macrophages and scavenger receptors in obesity-associated non-alcoholic liver fatty disease (NAFLD). | 2020 | Details |
| A06426 | 32884949 | J Immunol Res | Kangtaizhi Granule Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats and HepG2 Cells via AMPK/mTOR Signaling Pathway. | 2020 | Details |
| A06428 | 32884242 | Drug Des Devel Ther | Galangin Improved Non-Alcoholic Fatty Liver Disease in Mice by Promoting Autophagy. | 2020 | Details |
| A06429 | 32883523 | Biochem Biophys Res Commun | Long-term subcutaneous injection of lipopolysaccharides and high-fat diet induced non-alcoholic fatty liver disease through IKKε/ NF-κB signaling. | 2020 | Details |
| A06437 | 32881925 | PLoS One | Exchanging dietary fat source with extra virgin olive oil does not prevent progression of diet-induced non-alcoholic fatty liver disease and insulin resistance. | 2020 | Details |
| A06448 | 32878529 | Pharm Biol | Cyclocarya paliurus extract attenuates hepatic lipid deposition in HepG2 cells by the lipophagy pathway. | 2020 | Details |
| A06451 | 32877694 | Pharmacol Res | Scoparone as a therapeutic drug in liver diseases: Pharmacology, pharmacokinetics and molecular mechanisms of action. | 2020 | Details |
| A06454 | 32877213 | Am J Physiol Gastrointest Liver Physiol | High-fat diet induces fibrosis in mice lacking CYP2A5 and PPARα: a new model for steatohepatitis-associated fibrosis. | 2020 | Details |
| A06458 | 32874784 | PeerJ | Gender-specific associations between apolipoprotein A1 and arterial stiffness in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A06463 | 32870526 | J Gastroenterol Hepatol | Oxidative stress and Liver X Receptor agonist induce hepatocellular carcinoma in Non-alcoholic steatohepatitis model. | 2020 | Details |
| A06478 | 32863955 | Theranostics | Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. | 2020 | Details |
| A06481 | 32863214 | Redox Biol | Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy. | 2020 | Details |
| A06483 | 32862731 | Int J Food Sci Nutr | Dietary calamondin supplementation slows the progression of non-alcoholic fatty liver disease in C57BL/6 mice fed a high-fat diet. | 2020 | Details |
| A06492 | 32856322 | J Pharm Pharmacol | Therapeutic effects of açaí seed extract on hepatic steatosis in high-fat diet-induced obesity in male mice: a comparative effect with rosuvastatin. | 2020 | Details |
| A06500 | 32850919 | Front Med (Lausanne) | Intrahepatic Expression of Fatty Acid Translocase CD36 Is Increased in Obstructive Sleep Apnea. | 2020 | Details |
| A06510 | 32848877 | Front Physiol | Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation. | 2020 | Details |
| A06512 | 32848718 | Front Pharmacol | Delivery of microRNA-33 Antagomirs by Mesoporous Silica Nanoparticles to Ameliorate Lipid Metabolic Disorders. | 2020 | Details |
| A06516 | 32846589 | Food Res Int | Monascus purpureus-fermented common buckwheat protects against dyslipidemia and non-alcoholic fatty liver disease through the regulation of liver metabolome and intestinal microbiome. | 2020 | Details |
| A06522 | 32841505 | Liver Int | Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative. | 2020 | Details |
| A06535 | 32833701 | Curr Opin Clin Nutr Metab Care | Lifestyle interventions affecting hepatic fatty acid metabolism. | 2020 | Details |
| A06559 | 32825154 | Nutrients | The Protective Effect of Myristica fragrans Houtt. Extracts Against Obesity and Inflammation by Regulating Free Fatty Acids Metabolism in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06565 | 32824277 | Int J Mol Sci | Lactobacillus Strains Alleviated Hyperlipidemia and Liver Steatosis in Aging Rats via Activation of AMPK. | 2020 | Details |
| A06568 | 32823659 | Int J Mol Sci | Gut-Pancreas-Liver Axis as a Target for Treatment of NAFLD/NASH. | 2020 | Details |
| A06570 | 32823613 | Nutrients | Ethyl Acetate Fraction of Amomum xanthioides Ameliorates Nonalcoholic Fatty Liver Disease in a High-Fat Diet Mouse Model. | 2020 | Details |
| A06577 | 32821738 | J Lipid Atheroscler | Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion. | 2020 | Details |
| A06586 | 32819566 | Biochem Biophys Res Commun | Genetic ablation of Fas-activated serine/threonine kinase ameliorates obesity-related hepatic glucose and lipid metabolic disorders via sirtuin-1 signaling. | 2020 | Details |
| A06588 | 32818571 | J Hepatol | miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder. | 2020 | Details |
| A06591 | 32816363 | FASEB J | Identification of CYP46A1 as a new regulator of lipid metabolism through CRISPR-based whole-genome screening. | 2020 | Details |
| A06597 | 32812944 | Metabol Open | Regulation of hepatic genes related to lipid metabolism and antioxidant enzymes by sodium butyrate supplementation. | 2020 | Details |
| A06599 | 32812776 | Am J Physiol Gastrointest Liver Physiol | An overview of deregulated lipid metabolism in nonalcoholic fatty liver disease with special focus on lysosomal acid lipase. | 2020 | Details |
| A06600 | 32812775 | Am J Physiol Gastrointest Liver Physiol | Duodenal-jejunal bypass improves nonalcoholic fatty liver disease independently of weight loss in rodents with diet-induced obesity. | 2020 | Details |
| A06605 | 32810797 | J Nutr Biochem | A combined healthy strategy for successful weight loss, weight maintenance and improvement of hepatic lipid metabolism. | 2020 | Details |
| A06608 | 32810487 | Metabolism | Revealing the role of peroxisome proliferator-activated receptor β/δ in nonalcoholic fatty liver disease. | 2020 | Details |
| A06611 | 32809824 | J Med Chem | Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting. | 2020 | Details |
| A06613 | 32808114 | J Physiol Biochem | Potential roles of bone morphogenetic protein-9 in glucose and lipid homeostasis. | 2020 | Details |
| A06614 | 32808060 | Eur J Nutr | Betaine prevented high-fat diet-induced NAFLD by regulating the FGF10/AMPK signaling pathway in ApoE-/- mice. | 2020 | Details |
| A06617 | 32807146 | BMC Complement Med Ther | Regulation effects of total flavonoids in Morus alba L. on hepatic cholesterol disorders in orotic acid induced NAFLD rats. | 2020 | Details |
| A06627 | 32801462 | J Clin Biochem Nutr | Epigallocatechin-3-gallate (EGCG) attenuates non-alcoholic fatty liver disease via modulating the interaction between gut microbiota and bile acids. | 2020 | Details |
| A06631 | 32800834 | Life Sci | High fructose intake and the route towards cardiometabolic diseases. | 2020 | Details |
| A06643 | 32796650 | Metabolites | Metabolic Profiling Reveals Aggravated Non-Alcoholic Steatohepatitis in High-Fat High-Cholesterol Diet-Fed Apolipoprotein E-Deficient Mice Lacking Ron Receptor Signaling. | 2020 | Details |
| A06656 | 32791795 | Zhonghua Gan Zang Bing Za Zhi | [Construction of transmembrane 6 superfamily member 2 E167K gene knock-in mouse model by using CRISPR/Cas9 technology]. | 2020 | Details |
| A06666 | 32788910 | EXCLI J | Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-gamma gene expression. | 2020 | Details |
| A06669 | 32786868 | J Agric Food Chem | Fermented Soy Paste Alleviates Lipid Accumulation in the Liver by Regulating the AMPK Pathway and Modulating Gut Microbiota in High-Fat-Diet-Fed Rats. | 2020 | Details |
| A06670 | 32786176 | Zool Res | Assessment of mitochondrial function in metabolic dysfunction-associated fatty liver disease using obese mouse models. | 2020 | Details |
| A06671 | 32785220 | PLoS One | Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet. | 2020 | Details |
| A06674 | 32785059 | Nutrients | Metabolic Impact of Flavonoids Consumption in Obesity: From Central to Peripheral. | 2020 | Details |
| A06677 | 32783933 | Cell Rep | Activation of a Specific Gut Bacteroides-Folate-Liver Axis Benefits for the Alleviation of Nonalcoholic Hepatic Steatosis. | 2020 | Details |
| A06682 | 32781739 | Nutrients | The Root of Polygonum multiflorum Thunb. Alleviates Non-Alcoholic Steatosis and Insulin Resistance in High Fat Diet-Fed Mice. | 2020 | Details |
| A06685 | 32780887 | FASEB J | Hepatic E4BP4 induction promotes lipid accumulation by suppressing AMPK signaling in response to chemical or diet-induced ER stress. | 2020 | Details |
| A06691 | 32779442 | Cell J | Nicotinamide Phosphoribosyltransferase Knockdown Leads to Lipid Accumulation in HepG2 Cells through The SIRT1-AMPK Pathway. | 2020 | Details |
| A06694 | 32777482 | Biochim Biophys Acta Mol Cell Biol Lipids | Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions. | 2020 | Details |
| A06695 | 32777481 | Biochim Biophys Acta Mol Cell Biol Lipids | Hepatic and circulating levels of PCSK9 in morbidly obese patients: Relation with severity of liver steatosis. | 2020 | Details |
| A06697 | 32776921 | PLoS Genet | Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease. | 2020 | Details |
| A06709 | 32774148 | Mediators Inflamm | Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways. | 2020 | Details |
| A06710 | 32773176 | HPB (Oxford) | Cholecystectomy as a risk factor for non-alcoholic fatty liver disease development. | 2020 | Details |
| A06713 | 32772909 | Comb Chem High Throughput Screen | Evaluation of Insulin Resistance Induced Brain Tissue Dysfunction in Obese Dams and their Neonates: Role of Ipriflavone Amelioration. | 2021 | Details |
| A06715 | 32772323 | J Endocrinol Invest | Testosterone treatment is associated with reduced adipose tissue dysfunction and nonalcoholic fatty liver disease in obese hypogonadal men. | 2020 | Details |
| A06722 | 32769877 | Medicine (Baltimore) | Protective effect of probiotics in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A06736 | 32765626 | Evid Based Complement Alternat Med | Improvement in Menopause-Associated Hepatic Lipid Metabolic Disorders by Herbal Formula HPC03 on Ovariectomized Rats. | 2020 | Details |
| A06739 | 32765301 | Front Physiol | Lipophagy Impairment Is Associated With Disease Progression in NAFLD. | 2020 | Details |
| A06746 | 32762728 | BMC Pharmacol Toxicol | Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease. | 2020 | Details |
| A06748 | 32760938 | Food Funct | Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis. | 2020 | Details |
| A06750 | 32760200 | Int J Biol Sci | Bile acids mediated potential functional interaction between FXR and FATP5 in the regulation of Lipid Metabolism. | 2020 | Details |
| A06762 | 32756704 | Food Funct | Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice. | 2020 | Details |
| A06770 | 32753923 | Diabetes Metab Syndr Obes | Therapeutic Effects of Garlic on Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Patients: A Randomized Clinical Trial. | 2020 | Details |
| A06773 | 32751983 | Biomolecules | Arachidonic Acid as an Early Indicator of Inflammation during Non-Alcoholic Fatty Liver Disease Development. | 2020 | Details |
| A06775 | 32751794 | Int J Mol Sci | Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice. | 2020 | Details |
| A06776 | 32751772 | Nutrients | Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity. | 2020 | Details |
| A06785 | 32746850 | Cell Commun Signal | The crosstalk: exosomes and lipid metabolism. | 2020 | Details |
| A06797 | 32742127 | World J Gastroenterol | Monoacylglycerol lipase reprograms lipid precursors signaling in liver disease. | 2020 | Details |
| A06806 | 32738398 | Free Radic Biol Med | Generation of sphingosine-1-phosphate by sphingosine kinase 1 protects nonalcoholic fatty liver from ischemia/reperfusion injury through alleviating reactive oxygen species production in hepatocytes. | 2020 | Details |
| A06808 | 32738331 | Toxicol Appl Pharmacol | A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters. | 2020 | Details |
| A06812 | 32738061 | Hepatology | Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children. | 2020 | Details |
| A06814 | 32737656 | Inflammation | Electroacupuncture Attenuates Liver Inflammation in Nonalcoholic Fatty Liver Disease Rats. | 2020 | Details |
| A06818 | 32736139 | J Proteomics | Identification of p115 as a novel ACSL4 interacting protein and its role in regulating ACSL4 degradation. | 2020 | Details |
| A06820 | 32734608 | J Pharm Pharmacol | HWL-088, a new and highly effective FFA1/PPARδ dual agonist, attenuates nonalcoholic steatohepatitis by regulating lipid metabolism, inflammation and fibrosis. | 2020 | Details |
| A06823 | 32733940 | Biomed Res Int | An Overview of Lipid Metabolism and Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06824 | 32733933 | Biomed Res Int | Ginsenoside Rb1 Alleviated High-Fat-Diet-Induced Hepatocytic Apoptosis via Peroxisome Proliferator-Activated Receptor γ. | 2020 | Details |
| A06843 | 32726654 | Eur J Pharmacol | Neuregulin 4 alleviates hepatic steatosis via activating AMPK/mTOR-mediated autophagy in aged mice fed a high fat diet. | 2020 | Details |
| A06850 | 32724586 | Food Sci Nutr | Extraction and structural analysis of Angelica sinensis polysaccharide with low molecular weight and its lipid-lowering effect on nonalcoholic fatty liver disease. | 2020 | Details |
| A06854 | 32721044 | FASEB J | Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease. | 2020 | Details |