Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Atorvastatin111 records.
Article ID | PMID | Source | Title | Publish Year | |
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A00346 | 35126843 | World J Hepatol | Is there a role of lipid-lowering therapies in the management of fatty liver disease? | 2022 | Details |
A00554 | 35048107 | Eur Heart J | Polypill for prevention of cardiovascular diseases with focus on non-alcoholic steatohepatitis: the PolyIran-Liver trial. | 2022 | Details |
A01124 | 34862975 | FASEB J | Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling. | 2022 | Details |
A02213 | 34458376 | J Immunol Res | Probiotics Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats via Gut Microbiota/FXR/FGF15 Signaling Pathway. | 2021 | Details |
A02878 | 34208774 | Int J Mol Sci | Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis. | 2021 | Details |
A03371 | 34027116 | Clin Exp Hepatol | Comparative study of the effects of Abexol and atorvastatin in patients with non-alcoholic fatty liver disease. | 2021 | Details |
A03404 | 34014280 | Dis Model Mech | Synergic effect of atorvastatin and ambrisentan on sinusoidal and hemodynamic alterations in a rat model of NASH. | 2021 | Details |
A05750 | 33132768 | ScientificWorldJournal | Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin. | 2020 | Details |
A05930 | 33072533 | Adv Pharm Bull | The Evaluation of Effective Drugs for the Treatment of Non-Alcoholic Fatty Liver Disease: A Systematic Review and Network Meta-Analysis. | 2020 | Details |
A05967 | 33059580 | Curr Vasc Pharmacol | Prevalence, Diagnosis, and Treatment with 3 Different Statins of Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis in Military Personnel. Do Genetics Play a Role? | 2021 | Details |
A06936 | 32694178 | Gut | Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites. | 2020 | Details |
A06965 | 32684739 | World J Gastroenterol | Medications in type-2 diabetics and their association with liver fibrosis. | 2020 | Details |
A07152 | 32598715 | Ter Arkh | [Evaluation of the effectiveness of differentiated therapy of non-alcoholic fatty liver disease]. | 2020 | Details |
A08211 | 32202947 | Arch Physiol Biochem | All-Trans Retinoic Acid (atRA) effectively improves liver steatosis in a rabbit model of high fat induced liver steatosis. | 2020 | Details |
A08455 | 32104276 | Exp Ther Med | Atorvastatin promotes AMPK signaling to protect against high fat diet-induced non-alcoholic fatty liver in golden hamsters. | 2020 | Details |
A09006 | 31907123 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Intervention of Catalpol on High-fat Diet Induced Nonalcoholic Fatty Liver Disease in Mice]. | 2019 | Details |
A09079 | 31882668 | Sci Rep | Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH. | 2019 | Details |
A09433 | 31752351 | Nutrients | Atorvastatin and Vitamin E Accelerates NASH Resolution by Dietary Intervention in a Preclinical Guinea Pig Model. | 2019 | Details |
A10276 | 31402538 | Liver Int | CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients. | 2019 | Details |
A11279 | 30961499 | Curr Vasc Pharmacol | Non-Alcoholic Fatty Liver Disease Treatment in Patients with Type 2 Diabetes Mellitus; New Kids on the Block. | 2020 | Details |
A11998 | 30652643 | Curr Pharm Des | The Role of Statins in the Management of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
A12474 | 30431378 | Curr Med Res Opin | Severe nonalcoholic steatohepatitis and type 2 diabetes: liver histology after weight loss therapy in a randomized clinical trial. | 2018 | Details |
A13598 | 29887885 | Adv Pharmacol Sci | Supplementation with Alpha-Tocopherol and Ascorbic Acid to Nonalcoholic Fatty Liver Disease's Statin Therapy in Men. | 2018 | Details |
A13901 | 29702089 | Chem Biol Interact | Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase. | 2018 | Details |
A14824 | 29217477 | Biochim Biophys Acta Mol Cell Biol Lipids | Activation of hepatic Nogo-B receptor expression-A new anti-liver steatosis mechanism of statins. | 2017 | Details |
A15054 | 29117763 | Toxicol Mech Methods | Pilose antler peptide attenuates high-fat-diet-induced liver injury. | 2017 | Details |
A15424 | 28919478 | Biochim Biophys Acta Mol Cell Biol Lipids | Atorvastatin reduces lipid accumulation in the liver by activating protein kinase A-mediated phosphorylation of perilipin 5. | 2017 | Details |
A15606 | 28815679 | Clin Exp Pharmacol Physiol | (-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease. | 2017 | Details |
A15871 | 28676027 | Curr Vasc Pharmacol | The Co-Existence of NASH and Chronic Kidney Disease Boosts Cardiovascular Risk: Are there any Common Therapeutic Options? | 2018 | Details |
A15876 | 28676019 | Curr Vasc Pharmacol | Statins: An Under-Appreciated Asset for the Prevention and the Treatment of NAFLD or NASH and the Related Cardiovascular Risk. | 2018 | Details |
A15877 | 28676018 | Curr Vasc Pharmacol | Can Serum Uric Acid Lowering Therapy Contribute to the Prevention or Treatment of Nonalcoholic Fatty Liver Disease? | 2018 | Details |
A16062 | 28587208 | Mar Drugs | Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models. | 2017 | Details |
A16109 | 28565851 | Exp Ther Med | Pharmacological management of non-alcoholic fatty liver disease: Atorvastatin versus pentoxifylline. | 2017 | Details |
A16163 | 28529649 | Theranostics | SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway. | 2017 | Details |
A16460 | 28375109 | Pak J Pharm Sci | Anti hyperlipidemic and hepatoprotective effects of native date fruit variety "Aseel" (Phoenix dactylifera). | 2016 | Details |
A17506 | 27098507 | Diabetes Metab J | Statins Increase Mitochondrial and Peroxisomal Fatty Acid Oxidation in the Liver and Prevent Non-Alcoholic Steatohepatitis in Mice. | 2016 | Details |
A19020 | 26817117 | Eksp Klin Gastroenterol | [COMPARISON OF DIFFERENT TREATMENT REGIMENS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE]. | 2015 | Details |
A19267 | 26666731 | J Ethnopharmacol | The hepatoprotective effect of the combination use of Fructus Schisandrae with statin--A preclinical evaluation. | 2015 | Details |
A19920 | 26265520 | Arch Iran Med | PolyPill for Prevention of Cardiovascular Disease in an Urban Iranian Population with Special Focus on Nonalcoholic Steatohepatitis: A Pragmatic Randomized Controlled Trial within a Cohort (PolyIran - Liver) - Study Protocol. | 2015 | Details |
A20133 | 26134926 | Expert Opin Drug Saf | Evaluating the safety of Liptruzet (ezetimibe and atorvastatin): what are the potential benefits beyond low-density lipoprotein cholesterol-lowering effect? | 2015 | Details |
A20179 | 26104139 | Histol Histopathol | Effect of diet/atorvastatin on atherosclerotic lesions associated to nonalcoholic fatty liver disease in chickens. | 2015 | Details |
A20712 | 25786512 | Liver Int | Acute atorvastatin is hepatoprotective against ischaemia-reperfusion injury in mice by modulating eNOS and microparticle formation. | 2015 | Details |
A20841 | 25697114 | Med Hypotheses | Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH. | 2015 | Details |
A21090 | 25541989 | PLoS One | LDL-migration index (LDL-MI), an indicator of small dense low-density lipoprotein (sdLDL), is higher in non-alcoholic steatohepatitis than in non-alcoholic fatty liver: a multicenter cross-sectional study. | 2014 | Details |
A21091 | 25541279 | Prostaglandins Leukot Essent Fatty Acids | Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. | 2014 | Details |
A21123 | 25528845 | Lik Sprava | [Negative effects of termination statinotherapy in patients after acute coronary event with concominent non-alcoholic steatohepatitis]. | 2014 | Details |
A21141 | 25520429 | J Lipid Res | Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH. | 2014 | Details |
A22050 | 24850606 | Georgian Med News | [Optimization of long-term hypolipidemia treatment of patients with myocardial infarction in combination with non-alcoholic steatohepatitis]. | 2014 | Details |
A22171 | 24768901 | J Hepatol | Perilipin-5 is regulated by statins and controls triglyceride contents in the hepatocyte. | 2014 | Details |
A22668 | 24374462 | Cochrane Database Syst Rev | Statins for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. | 2013 | Details |
A22672 | 24373179 | Diabetes Obes Metab | APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome. | 2014 | Details |
A22700 | 25796814 | Wiad Lek | Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis. | 2014 | Details |
A22997 | 24127654 | Curr Med Res Opin | Are statins 'IDEAL' for non-alcoholic fatty liver disease? | 2013 | Details |
A23354 | 23847661 | Arch Med Sci | Statins and cardiovascular outcomes in elderly and younger patients with coronary artery disease: a post hoc analysis of the GREACE study. | 2013 | Details |
A23768 | 23500152 | J Hepatol | Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome. | 2013 | Details |
A24188 | 23140546 | Curr Vasc Pharmacol | The impact of smoking on cardiovascular outcomes and comorbidities in statin-treated patients with coronary artery disease: a post hoc analysis of the GREACE study. | 2013 | Details |
A24543 | 22770622 | Expert Opin Pharmacother | The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges. | 2012 | Details |
A24852 | 22432744 | J Gastroenterol Hepatol | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | Details |
A24872 | 22418885 | Semin Liver Dis | Dyslipidemia in patients with nonalcoholic fatty liver disease. | 2012 | Details |
A24973 | 22291824 | Arch Med Sci | Safety and impact on cardiovascular events of long-term multifactorial treatment in patients with metabolic syndrome and abnormal liver function tests: a post hoc analysis of the randomised ATTEMPT study. | 2011 | Details |
A24997 | 22265683 | Dig Liver Dis | Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property. | 2012 | Details |
A25203 | 22096112 | Eur J Endocrinol | Recent advances in cardiovascular aspects of polycystic ovary syndrome. | 2011 | Details |
A25299 | 21986643 | Curr Opin Lipidol | Cholesterol-lowering therapy for the treatment of nonalcoholic fatty liver disease: an update. | 2011 | Details |
A25587 | 21684478 | Arab J Gastroenterol | Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin. | 2011 | Details |
A25955 | 21269482 | Lipids Health Dis | Comparison of dietary control and atorvastatin on high fat diet induced hepatic steatosis and hyperlipidemia in rats. | 2011 | Details |
A26004 | 21218508 | Diabetes Metab Res Rev | Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia. | 2011 | Details |
A26007 | 21212755 | Am J Gastroenterol | Effect of atorvastatin, vitamin E and C on nonalcoholic fatty liver disease: is the combination required? | 2011 | Details |
A26090 | 21122807 | Toxicol Appl Pharmacol | Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment. | 2010 | Details |
A26098 | 21109302 | Lancet | Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis. | 2010 | Details |
A26248 | 20842109 | Am J Gastroenterol | Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial. | 2010 | Details |
A26602 | 20112031 | J Gastroenterol | Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH. | 2010 | Details |
A26701 | 19932590 | Biomed Pharmacother | Effect of atorvastatin and diet on non-alcoholic fatty liver disease activity score in hyperlipidemic chickens. | 2009 | Details |
A27235 | 18936912 | Naunyn Schmiedebergs Arch Pharmacol | A role for atorvastatin and insulin combination in protecting from liver injury in a model of type 2 diabetes with hyperlipidemia. | 2008 | Details |
A27469 | 18330098 | Acta Gastroenterol Belg | Statins in hepatobiliary diseases: effects, indications and risks. | 2008 | Details |
A27485 | 18302012 | Inflammation | Effects of traditional chinese medicine on endotoxin and its receptors in rats with non-alcoholic steatohepatitis. | 2008 | Details |
A27970 | 16842328 | Liver Int | Intracellular retention of hepatic serpins caused by severe hyperlipidemia. | 2006 | Details |
A28016 | 16709309 | Curr Med Res Opin | Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study. | 2006 | Details |
A28024 | 16696815 | Aliment Pharmacol Ther | A pilot study of atorvastatin treatment in dyslipemid, non-alcoholic fatty liver patients. | 2006 | Details |
A28376 | 15333967 | Indian J Gastroenterol | Efficacy of omega-3 fatty acids, atorvastatin and orlistat in non-alcoholic fatty liver disease with dyslipidemia. | 2004 | Details |
A28459 | 14585234 | Curr Treat Options Gastroenterol | Treatment of Nonalcoholic Fatty Liver Disease. | 2003 | Details |
A30133 | 32924771 | J Pharm Pract | Statin Associated Autoimmune Myonecrosis: Case Report With Delayed Onset and Treatment Challenges. | 2020 | Details |
A30156 | 32882802 | Antioxidants (Basel) | Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation. | 2020 | Details |
A36094 | 19013295 | Metabolism | Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia. | 2008 | Details |
A36711 | 17410287 | J Gastrointestin Liver Dis | Therapeutic options in non-alcoholic steatohepatitis (NASH). Are all agents alike? Results of a preliminary study. | 2007 | Details |
A37781 | 14679419 | Can J Gastroenterol | Ursodeoxycholic acid and atorvastatin in the treatment of nonalcoholic steatohepatitis. | 2003 | Details |
A43781 | 30894877 | Evid Based Complement Alternat Med | BuShenKangShuai Tablet Alleviates Hepatic Steatosis via Improving Liver Adiponectin Resistance in ApoE-/- Mice. | 2019 | Details |
A44438 | 28628040 | J Clin Invest | Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity. | 2017 | Details |
A44450 | 28596414 | Am J Physiol Gastrointest Liver Physiol | Letter to the editor: Treating nonalcoholic fatty liver disease with statins. Are all statins equal? | 2017 | Details |
A44650 | 27807313 | Hong Kong Med J | Effect of combined use of Fructus Schisandrae and statin on high-fat-diet-induced metabolic syndrome in rats. | 2016 | Details |
A44758 | 27419149 | Open Forum Infect Dis | Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus. | 2016 | Details |
A45721 | 23099228 | Dig Liver Dis | Author reply: comment to "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
A45725 | 23058851 | Dig Liver Dis | Comment to "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
A45758 | 22917635 | Dig Liver Dis | Comment on "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
A45759 | 22909420 | Dig Liver Dis | Author reply: comment to "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
A45773 | 22823912 | J Gastroenterol Hepatol | Enhancing organ pool by statins: is this the future? | 2012 | Details |
A45797 | 22686718 | Natl Med J India | Atorvastatin and antioxidants: the remedy for non-alcoholic fatty liver disease? | 2012 | Details |
A45831 | 22487461 | Dig Liver Dis | If steatosis is the atherosclerosis of the liver, are statins the "aspirin" for steatosis? | 2012 | Details |
A46272 | 19877024 | Liver Transpl | Obesity, hyperlipidemia, and metabolic syndrome. | 2009 | Details |
A46273 | 19875919 | Turk Kardiyol Dern Ars | The relationship between nonalcoholic fatty liver disease and the severity of coronary artery disease in patients with metabolic syndrome. | 2009 | Details |
A46743 | 15989845 | Med Clin (Barc) | [Medical management of primary nonalcoholic fatty liver disease]. | 2005 | Details |