Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Zinc141 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00623 | 35024308 | Acta Pharm Sin B | Proteomics and metabolic phenotyping define principal roles for the aryl hydrocarbon receptor in mouse liver. | 2021 | Details |
| A00782 | 34967199 | Asia Pac J Clin Nutr | Dietary iron and zinc intakes and nonalcoholic fatty liver disease: A meta-analysis. | 2021 | Details |
| A01316 | 34789275 | J Nanobiotechnology | A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis. | 2021 | Details |
| A01373 | 34771023 | Molecules | Zinc as a Drug for Wilson's Disease, Non-Alcoholic Liver Disease and COVID-19-Related Liver Injury. | 2021 | Details |
| A01435 | 34746842 | Curr Res Physiol | High-fat diet-associated cognitive decline: Is zinc finger protein 1 (ZPR1) the molecular connection? | 2021 | Details |
| A01935 | 34558842 | Hepatol Commun | Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort. | 2021 | Details |
| A02535 | 34337376 | Metabol Open | The role of zinc in the prevention and treatment of nonalcoholic fatty liver disease. | 2021 | Details |
| A02795 | 34237252 | Cell Metab | Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication. | 2021 | Details |
| A03145 | 34114341 | J Cell Mol Med | USP11 degrades KLF4 via its deubiquitinase activity in liver diseases. | 2021 | Details |
| A04730 | 33525359 | Int J Mol Sci | Fatty Acids and a High-Fat Diet Induce Epithelial-Mesenchymal Transition by Activating TGFβ and β-Catenin in Liver Cells. | 2021 | Details |
| A04842 | 33487290 | Clin Nutr ESPEN | The association between dietary antioxidant index (DAI) and nonalcoholic fatty liver disease (NAFLD) onset; new findings from an incident case-control study. | 2020 | Details |
| A05029 | 33404166 | Int J Clin Pract | The association of the adipokine zinc-alpha2-glycoprotein with non-alcoholic fatty liver disease and related risk factors: A comprehensive systematic review. | 2021 | Details |
| A05773 | 33125573 | Mikrochim Acta | Immobilization of cell membrane onto a glucose-Zn-based porous coordination polymer and its application to rapid screening of potentially active compounds from Vaccinium corymbosum L. leaves. | 2020 | Details |
| A05867 | 33095789 | PLoS One | Serum zinc level and hepatic fibrosis in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A06004 | 33040080 | Cell Death Dis | USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638. | 2020 | Details |
| A06129 | 32995080 | PeerJ | Association between serum and dietary antioxidant micronutrients and advanced liver fibrosis in non-alcoholic fatty liver disease: an observational study. | 2020 | Details |
| A06292 | 32939643 | Biol Trace Elem Res | Zinc Supplementation and Strength Exercise in Rats with Type 2 Diabetes: Akt and PTP1B Phosphorylation in Nonalcoholic Fatty Liver. | 2020 | Details |
| A06316 | 32932174 | J Trace Elem Med Biol | The effects of zinc supplementation on metabolic profile and oxidative stress in overweight/obese patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
| A06665 | 32789148 | Clin Nutr Res | Association between Inflammatory Biomarkers and Nutritional Status in Fatty Liver. | 2020 | Details |
| A06706 | 32774765 | World J Gastrointest Surg | Role of micronutrients in staging of nonalcoholic fatty liver disease: A retrospective cross-sectional study. | 2020 | Details |
| A06982 | 32674425 | Nutrients | Current Trends of Essential Trace Elements in Patients with Chronic Liver Diseases. | 2020 | Details |
| A07722 | 32376267 | Life Sci | Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress. | 2020 | Details |
| A07982 | 32290656 | J Agric Food Chem | Zinc Supplementation Alleviates Lipid and Glucose Metabolic Disorders Induced by a High-Fat Diet. | 2020 | Details |
| A08119 | 32240652 | Biochem Pharmacol | Pyrvinium pamoate attenuates non-alcoholic steatohepatitis: Insight on hedgehog/Gli and Wnt/β-catenin signaling crosstalk. | 2020 | Details |
| A08350 | 32146412 | Sci Total Environ | Non-linear association of serum molybdenum and linear association of serum zinc with nonalcoholic fatty liver disease: Multiple-exposure and Mendelian randomization approach. | 2020 | Details |
| A08692 | 32020523 | Biol Trace Elem Res | The Effect of Zinc Supplementation on Steatosis Severity and Liver Function Enzymes in Overweight/Obese Patients with Mild to Moderate Non-alcoholic Fatty Liver Following Calorie-Restricted Diet: a Double-Blind, Randomized Placebo-Controlled Trial. | 2020 | Details |
| A08758 | 31998789 | Biomed Res Int | Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1. | 2020 | Details |
| A08866 | 31957704 | Eur Cytokine Netw | lncRNA NEAT1 regulates fibrosis and inflammatory response induced by nonalcoholic fatty liver by regulating miR-506/GLI3. | 2019 | Details |
| A09217 | 31832925 | Biol Trace Elem Res | Effect of Zn Supplementation on Trace Element Status in Rats with Diet-Induced Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09455 | 31740790 | Cell Death Differ | Tumor suppressor ZHX2 inhibits NAFLD-HCC progression via blocking LPL-mediated lipid uptake. | 2019 | Details |
| A09581 | 31688305 | Eur J Gastroenterol Hepatol | Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A09881 | 31576092 | World J Gastroenterol | Zinc-α2-glycoprotein 1 attenuates non-alcoholic fatty liver disease by negatively regulating tumour necrosis factor-α. | 2019 | Details |
| A09998 | 31531097 | Iran J Pathol | The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A10206 | 31433263 | Nutr Cancer | Serum Nutritional Markers as Prognostic Factors for Hepatic and Extrahepatic Carcinogenesis in Japanese Patients with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10259 | 31408567 | Hepatol Res | Identification of two microRNA nodes as potential cooperative modulators of liver metabolism. | 2019 | Details |
| A10462 | 31326093 | Am J Med Sci | Association Between Index of Nutritional Quality and Nonalcoholic Fatty Liver Disease: The Role of Vitamin D and B Group. | 2019 | Details |
| A11853 | 30708053 | Nanomedicine | Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis. | 2019 | Details |
| A12078 | 30611703 | Alcohol | Effect of nanoformulated copper/zinc superoxide dismutase on chronic ethanol-induced alterations in liver and adipose tissue. | 2019 | Details |
| A13066 | 30154417 | Cell Death Dis | JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism. | 2018 | Details |
| A13368 | 30014284 | Biol Trace Elem Res | Evaluation of Plasma Trace Elements in Different Stages of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13372 | 30013137 | Nat Commun | Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis. | 2018 | Details |
| A13384 | 30006580 | Int J Obes (Lond) | Zinc alpha2 glycoprotein protects against obesity-induced hepatic steatosis. | 2018 | Details |
| A13583 | 29895370 | J Trace Elem Med Biol | Expression of zinc transporters ZIP4, ZIP14 and ZnT9 in hepatic carcinogenesis-An immunohistochemical study. | 2018 | Details |
| A14008 | 29637446 | J Physiol Biochem | Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients. | 2018 | Details |
| A14053 | 29608898 | Eur J Pharmacol | Canagliflozin protects against non-alcoholic steatohepatitis in type-2 diabetic rats through zinc alpha-2 glycoprotein up-regulation. | 2018 | Details |
| A14093 | 29590715 | Acta Clin Croat | Nutritional Status and Nutrition Quality in Patients with Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A14157 | 29560688 | Acta Gastroenterol Belg | Prevalence of fat-soluble vitamin (A, D, and E) and zinc deficiency in patients with cirrhosis being assessed for liver transplantation. | 2018 | Details |
| A14470 | 29398749 | Iran J Med Sci | Regression of Nonalcoholic Fatty Liver Disease with Zinc and Selenium Co-supplementation after Disease Progression in Rats. | 2018 | Details |
| A14490 | 29385682 | Nutrients | Serum Antioxidant Associations with Metabolic Characteristics in Metabolically Healthy and Unhealthy Adolescents with Severe Obesity: An Observational Study. | 2018 | Details |
| A15881 | 28673968 | Proc Natl Acad Sci U S A | Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress. | 2017 | Details |
| A15934 | 28645738 | J Hepatol | Human germline hedgehog pathway mutations predispose to fatty liver. | 2017 | Details |
| A16090 | 28577233 | Biol Trace Elem Res | Zinc and Selenium Co-supplementation Reduces Some Lipid Peroxidation and Angiogenesis Markers in a Rat Model of NAFLD-Fed High Fat Diet. | 2017 | Details |
| A16548 | 28322865 | Life Sci | Palmitic acid elicits hepatic stellate cell activation through inflammasomes and hedgehog signaling. | 2017 | Details |
| A16877 | 28115335 | BMJ Open | Association between soil heavy metals and fatty liver disease in men in Taiwan: a cross sectional study. | 2017 | Details |
| A16975 | 28067590 | Biosci Biotechnol Biochem | BCL11B gene heterozygosity causes weight loss accompanied by increased energy consumption, but not defective adipogenesis, in mice. | 2017 | Details |
| A17014 | 28049265 | Asia Pac J Clin Nutr | Increased dietary zinc and vitamin B-2 is associated with increased alanine aminotransferase in Taiwanese adolescents. | 2017 | Details |
| A17118 | 27982256 | Acta Cir Bras | Effect of curcumin on visfatin and zinc-α2-glycoprotein in a rat model of non-alcoholic fatty liver disease. | 2016 | Details |
| A17428 | 27788707 | Zhonghua Gan Zang Bing Za Zhi | [Effect of JAZF1 over-expression on high-fat diet-induced non-alcoholic fatty liver disease]. | 2016 | Details |
| A17744 | 27625763 | Int J Prev Med | Intake of Nutrients, Fiber, and Sugar in Patients with Nonalcoholic Fatty Liver Disease in Comparison to Healthy Individuals. | 2016 | Details |
| A18249 | 27264075 | Mol Cell Endocrinol | Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes. | 2016 | Details |
| A18353 | 27185526 | Elife | Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis. | 2016 | Details |
| A18647 | 27016407 | Toxicol Lett | Mancozeb, a fungicide routinely used in agriculture, worsens nonalcoholic fatty liver disease in the human HepG2 cell model. | 2016 | Details |
| A18724 | 26981929 | Free Radic Res | Cu,Zn-SOD deficiency induces the accumulation of hepatic collagen. | 2016 | Details |
| A20218 | 26078820 | Oxid Med Cell Longev | Rimonabant Improves Oxidative/Nitrosative Stress in Mice with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20295 | 26041952 | J Clin Exp Hepatol | Reprint of: Nutrition in the Management of Cirrhosis and its Neurological Complications. | 2015 | Details |
| A20531 | 25906757 | J Endocrinol Invest | 1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats. | 2015 | Details |
| A20753 | 25755550 | J Clin Exp Hepatol | Nutrition in the management of cirrhosis and its neurological complications. | 2013 | Details |
| A21441 | 25316683 | JPEN J Parenter Enteral Nutr | Branched-Chain Amino Acid-Rich Supplements Containing Microelements Have Antioxidant Effects on Nonalcoholic Steatohepatitis in Mice. | 2014 | Details |
| A21897 | 24975050 | Basic Clin Pharmacol Toxicol | Effects of antihypertensive and triglyceride-lowering agents on hepatic copper concentrations in rats with fatty liver disease. | 2014 | Details |
| A22029 | 24867776 | Biol Trace Elem Res | Effect of oleic acid on the levels of eight metal ions in human hepatoma SMMC-7721 cells. | 2014 | Details |
| A22043 | 24854865 | FEBS J | Overexpression of juxtaposed with another zinc finger gene 1 reduces proinflammatory cytokine release via inhibition of stress-activated protein kinases and nuclear factor-κB. | 2014 | Details |
| A22054 | 24849253 | PLoS One | Deletion of nardilysin prevents the development of steatohepatitis and liver fibrotic changes. | 2014 | Details |
| A22761 | 24325457 | J Med Food | The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD. | 2013 | Details |
| A23310 | 23875703 | Clin Sci (Lond) | Involvement of the HIF-1α and Wnt/β-catenin pathways in the protective effects of losartan on fatty liver graft with ischaemia/reperfusion injury. | 2014 | Details |
| A23495 | 23727306 | J Hepatol | Dendritic cells in liver injury and fibrosis: shortcomings and promises. | 2013 | Details |
| A23607 | 23630437 | Int J Med Sci | Status of essential trace minerals and oxidative stress in viral hepatitis C patients with nonalcoholic fatty liver disease. | 2013 | Details |
| A24016 | 23300059 | Hepatology | Hedgehog pathway and pediatric nonalcoholic fatty liver disease. | 2013 | Details |
| A24113 | 23218652 | Gastroenterol Hepatol | [Acute liver failure after bariatric surgery. A case report and literature review]. | 2012 | Details |
| A24131 | 23197979 | Gastroenterol Res Pract | Nutrition therapy for liver diseases based on the status of nutritional intake. | 2012 | Details |
| A25051 | 22213086 | Hepatology | Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease. | 2012 | Details |
| A25228 | 22076166 | Int J Clin Exp Pathol | Increased expression of zinc finger protein 267 in non-alcoholic fatty liver disease. | 2011 | Details |
| A26110 | 21077793 | Clin Chem Lab Med | Serum zinc-α2-glycoprotein concentrations in patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A26182 | 20943080 | Zhonghua Gan Zang Bing Za Zhi | [The role of heme oxygenase-1 in non-alcoholic steatohepatitis]. | 2010 | Details |
| A27416 | 18422963 | J Gastroenterol Hepatol | Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis. | 2008 | Details |
| A27543 | 18095746 | Drug Saf | Orlistat-associated adverse effects and drug interactions: a critical review. | 2008 | Details |
| A27839 | 17296492 | J Nutr Biochem | Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition. | 2007 | Details |
| A27884 | 17140767 | Nutrition | Dietary habits and nutrient intake in non-alcoholic steatohepatitis. | 2006 | Details |
| A28784 | 35006616 | Hepatology | The RSPO-LGR4/5-ZNRF3/RNF43 module in liver homeostasis, regeneration, and disease. | 2022 | Details |
| A29108 | 34545586 | Hepatology | The transcription factor zinc fingers and homeoboxes 2 alleviates NASH by transcriptional activation of phosphatase and tensin homolog. | 2022 | Details |
| A29380 | 34159305 | JHEP Rep | Novel vectors and approaches for gene therapy in liver diseases. | 2021 | Details |
| A29448 | 34052659 | Biochem Biophys Res Commun | SFPQ associated with a co-activator for PPARγ, HELZ2, regulates key nuclear factors for adipocyte differentiation. | 2021 | Details |
| A32569 | 28085645 | J Toxicol Environ Health A | A physiologically based pharmacokinetic model for the broad-spectrum antimicrobial zinc pyrithione: I. Development and verification. | 2017 | Details |
| A33459 | 25956647 | J Hazard Mater | Cement kiln dust (CKD)-filter sand permeable reactive barrier for the removal of Cu(II) and Zn(II) from simulated acidic groundwater. | 2015 | Details |
| A34957 | 22153941 | Bioorg Med Chem Lett | Lead optimisation of selective non-zinc binding inhibitors of MMP13. Part 2. | 2011 | Details |
| A35167 | 21547909 | J Pathol | Increased production of sonic hedgehog by ballooned hepatocytes. | 2011 | Details |
| A37897 | 12830008 | Hepatology | Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis. | 2003 | Details |
| A42504 | 34358714 | Cell Mol Gastroenterol Hepatol | Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling. | 2021 | Details |
| A43092 | 32590463 | Chin Med J (Engl) | Association of serum zinc-α2-glycoprotein with non-alcoholic fatty liver disease. | 2020 | Details |
| A44224 | 29342898 | Nutrients | Associations between Zinc Deficiency and Metabolic Abnormalities in Patients with Chronic Liver Disease. | 2018 | Details |
| A46909 | 34774847 | Am J Pathol | ZFP36L1 Regulates Fgf21 mRNA Turnover and Modulates Alcoholic Hepatic Steatosis and Inflammation in Mice. | 2021 | Details |